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innate adaptive - El Corte Inglés
innate adaptive - El Corte Inglés

... tolerance involving both innate and adaptive immune pathways. • Multiple triggers are likely to be involved in disease initiation and perpetuation. • Continuous exposure to excess nucleic acid containing material amplifies the disease process. • Chronic inflammation can set up aberrant activation pa ...
Glomerular diseases
Glomerular diseases

... phase)  localized anaphylaxis = atopy (asthma, hay fever, eczema, hives) systemic anaphylaxis – circulatory shock, dyspnea, laryngospasm Ts activity  Type II: cytotoxic Cell-mediated cytotoxicity requires prior binding of antibodies to target cells ...
Ch.40 - Jamestown School District
Ch.40 - Jamestown School District

...  Asthma - a chronic respiratory disease where the air passages become narrower than normal  It causes wheezing, coughing, & difficulty in breathing  Asthma attacks can be triggered by infections, exercise, stress, etc. ...
Differentially Expressed Gene Therapy for the Early Detection of
Differentially Expressed Gene Therapy for the Early Detection of

... cases of T-LGL leukemia are usually treated with combination chemotherapy. Current research suggests that LGL leukemia is likely an antigen driven event. However, independent of the factors involved in the initiation of this disease, the final effect is the emergence of a lymphoproliferative disorde ...
Thyroid Autoimmune Diseases
Thyroid Autoimmune Diseases

... • Family history of thyroid disease. • HLA gene polymorphism (DR3,DR4, DR5). • CTLA-4 *gene polymorphism (cytotoxic Tlymphocyte associated protein) result in reduced negative regulation of T-cells. • Most common in middle-aged, starts in adulthood. • Woman to men ratio is 5-10: 1. • Associated with ...
If you Google Auto-Immune disease, you`ll find that it is a process
If you Google Auto-Immune disease, you`ll find that it is a process

... was going through extreme hills and valleys. His wife questioned him about stress at work and they frequently fought over things that ‘bothered him’ that previously were never an issue in their 9 years of marriage. Robert refused to go to counseling but did agree to a visit to the family doctor. Aft ...
Immunology
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... In a class of diseases known as autoimmune disorders, the body's immune system attacks its own tissues ...
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Activated PI3K Syndrome: PIK3R1 Disease Fact Sheet

... Effector T cell—A type of immune system cell that performs the functions of an immune response such as cell killing and cell activation. There are several different subtypes, each with a specific role. Gene—A unit of heredity that is transferred from parent to child. Genes are made up of DNA. Immune ...
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... (b) occurs when the immune system attacks the body’s own pathogens (c) occurs when the immune system fails to recognize the body’s own molecules as belonging to the person (d) occurs when the immune system fails to recognize foreign molecules as belonging to the person 28. Types 1 diabetes (a) attac ...
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Clustering of anti-GBM..., McAdoo and Pusey - Spiral

... serologically confirmed, reported in the same era21,22. Other specific infectious associations with antiGBM disease, however, have not been reported, and the precise mechanisms via which infection might initiate disease are not defined. It is conceivable that non-specific inflammation at the time of ...
Vaccination in autoimmune diseases
Vaccination in autoimmune diseases

... Infections and vaccinations are often associated with the development of autoimmune diseases (AID). Infections may trigger AID via antigen-specific (molecular mimicry) or antigen-nonspecific mechanisms (bystander activation). By contrast, a protective role of infections has also been proposed. The h ...
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Regents Biology Jonas Salk Developed first vaccine against polio

... Cell A is a white blood cell engulfing disease-causing organisms. 3. Cell A is a cancer cell produced by the immune system and it is helping to prevent disease. 4. Cell A is protecting bacteria so they can reproduce without being destroyed by predators. ...
Immunology Basics 1 - 8 Oct 2015
Immunology Basics 1 - 8 Oct 2015

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Nutritional Diseases - Extension Veterinary Medicine

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KIDNEY DAMAGE IN AUTOIMMUNE DISEASES
KIDNEY DAMAGE IN AUTOIMMUNE DISEASES

... glomerulonephritis (focal or diffuse, and membranoproliferative) have been reported in primary Sjögren’s syndrome. In such cases the possibility of overlap with systemic lupus should be considered (6). Rheumatoid arthritis Although early studies described a condition called rheumatoid glomerulonephr ...
Role of coconut oil in regulating autoimmune disorders
Role of coconut oil in regulating autoimmune disorders

... known as an autoimmune disorder. During this disorder our own immune system is not able to figure out the difference between good tissue and bad tissue and in this confusion it also attacks and destroys the healthy body tissues. There are 80+ autoimmune disorders [2]. Autoimmune problems leads to a ...
PDF - Bentham Open
PDF - Bentham Open

... Translational Medicine and Therapeutics, and 4Bone & Joint Research Unit, Queen Mary University of London, EC1M 6BQ London, United Kingdom; E-mail: [email protected] This study reveals the therapeutic efficacy and mechanisms of action of the ginger species Halia Bara, or Zingiber officinale Roscoe var. ...
Immunology 2
Immunology 2

... This is a new proposed type of hypersensitivity and involves antibodies binding to hormone receptors which results in the gland over-secreting that hormone. E.g.  Graves Disease: Hyperthyroidism, antibody acts as TSH (thyroid stimulating hormone). ...
Commenatry case
Commenatry case

... • unlike the other immune-mediated cytopenias that can be seen in patients with thymoma, the cytopenia associated with Good’s syndrome does not improve with glucocorticoids or Immunosuppressive therapy ...
Organ-specific Autoimmune Disease: A Deficiency of
Organ-specific Autoimmune Disease: A Deficiency of

... It is well appreciated that organ-specific autoimmune diseases run in families, but that within a family one member may have type 1 diabetes, another autoimmune thyroid disease, and another multiple sclerosis (1). What causes clustering of different autoimmune diseases along genetic lines, and what ...
The Immune Response
The Immune Response

... • The T-cells then bind to B-cells causing them to divide and produce plasma cells and memory B cells • Plasma cells secrete antibodies • Memory B cells and antibodies stay in the bloodstream and attack and mark the antigens quickly for destruction by macrophages the next time they enter the body • ...
Vaccines Largest Cause of Insulin
Vaccines Largest Cause of Insulin

... milk were about 50% less likely to develop proteins that are associated with type 1 diabetes. Thus, Akerblom postulates, cow's milk may cause diabetes in genetically at-risk kids. Other studies have already found that infants fed cow's milk are no more likely to develop the disease than infants who ...
1 - What a Year!
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... Lyme disease is one of many autoimmune diseases thought to develop by the mimicry of a self-protein. What are some other examples of such autoimmune diseases? The HLA-DR4 allele has been implicated in other autoimmune diseases such as rheumatoid arthritis. How else does this allele affect the body? ...
Possible Applications Basic overview
Possible Applications Basic overview

... known cure, there is a growing and urgent need for more specific and effective therapeutics. Researchers from Trinity College Dublin have discovered a novel method of suppressing the induction of a specific subtype of T cell responses in vivo, which are fundamental players in autoimmune and inflamma ...
Pediatric Infectious Disease Learning Objectives
Pediatric Infectious Disease Learning Objectives

... Cultural, ethnic, and socioeconomic factors also affect personal and family traits and behaviors, with varying effects on child rearing practices. Recognition of and respect for difference are important. The physician’s primary obligation is to promote the best interest of the patient. Students have ...
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Autoimmunity

Autoimmunity is the system of immune responses of an organism against its own cells and tissues. Any disease that results from such an aberrant immune response is termed an autoimmune disease. Prominent examples include Celiac disease, diabetes mellitus type 1, Sarcoidosis, systemic lupus erythematosus (SLE), Sjögren's syndrome, Churg-Strauss Syndrome, Hashimoto's thyroiditis, Graves' disease, idiopathic thrombocytopenic purpura, Addison's Disease, rheumatoid arthritis (RA), Polymyositis (PM), and Dermatomyositis (DM). Autoimmune diseases are very often treated with steroids.The misconception that an individual's immune system is totally incapable of recognizing self antigens is not new. Paul Ehrlich, at the beginning of the twentieth century, proposed the concept of horror autotoxicus, wherein a ""normal"" body does not mount an immune response against its own tissues. Thus, any autoimmune response was perceived to be abnormal and postulated to be connected with human disease. Now, it is accepted that autoimmune responses are an integral part of vertebrate immune systems (sometimes termed ""natural autoimmunity""), normally prevented from causing disease by the phenomenon of immunological tolerance to self-antigens. Autoimmunity should not be confused with alloimmunity.
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