Gene Linkage Genetics
... the genes, located on the same chromosome, must be close enough to each other. ...
... the genes, located on the same chromosome, must be close enough to each other. ...
Gene Mapping, Linked & Unlinked Genes
... the genes, located on the same chromosome, must be close enough to each other. ...
... the genes, located on the same chromosome, must be close enough to each other. ...
Gene Section IGL (Immunoglobulin Lambda) Atlas of Genetics and Cytogenetics
... immunoglobulin lambda chains. They result from the recombination (or rearrangement), at the DNA level, of two genes: IGLV and IGLJ, with deletion of the intermediary DNA to create a rearranged IGLV-J gene. The rearranged IGLV-J gene is transcribed with one of the IGLC genes and translated into an im ...
... immunoglobulin lambda chains. They result from the recombination (or rearrangement), at the DNA level, of two genes: IGLV and IGLJ, with deletion of the intermediary DNA to create a rearranged IGLV-J gene. The rearranged IGLV-J gene is transcribed with one of the IGLC genes and translated into an im ...
Bio II Ch 19 Eukaryotic Genomes
... shortens with each round of replication and they bind to proteins that protect the ends of chromosomes from degradation and fusion with other chromosomes. ...
... shortens with each round of replication and they bind to proteins that protect the ends of chromosomes from degradation and fusion with other chromosomes. ...
The human genome. Implications for medicine and society
... of 200 to 300 bases, which can be “drawn up” from the whole of the genome with the use of a form of the polymerase chain reaction technique (electronic polymerase chain reaction, ePCR)31. Given the fact that oligonucleotide primers, necessary for PCR implementation, are unique for each STS and are p ...
... of 200 to 300 bases, which can be “drawn up” from the whole of the genome with the use of a form of the polymerase chain reaction technique (electronic polymerase chain reaction, ePCR)31. Given the fact that oligonucleotide primers, necessary for PCR implementation, are unique for each STS and are p ...
PowerPoint File, 13.82 MB
... Summary (Part II) • It is widely accepted that allelic diversity is reduced by domestication. We now know that not only alleles but entire genes can be lost during domestication • ~2,000 expressed genes present in teosinte are missing from the B73 genome. 72 of these genes are missing from all othe ...
... Summary (Part II) • It is widely accepted that allelic diversity is reduced by domestication. We now know that not only alleles but entire genes can be lost during domestication • ~2,000 expressed genes present in teosinte are missing from the B73 genome. 72 of these genes are missing from all othe ...
Genes required for Lactococcus garvieae survival in a fish host
... rescue of mutants with attenuated virulence, genomic DNA previously digested with EcoRI was religated and the ligation mixture was used for transforming E. coli DH5lpir electrocompetent cells. Transformants were selected on 26 TY agar plates containing 100 mg ampicillin ml21. Plasmid DNA was obtaine ...
... rescue of mutants with attenuated virulence, genomic DNA previously digested with EcoRI was religated and the ligation mixture was used for transforming E. coli DH5lpir electrocompetent cells. Transformants were selected on 26 TY agar plates containing 100 mg ampicillin ml21. Plasmid DNA was obtaine ...
Functional gene groups are concentrated within chromosomes
... unique position were kept. This preliminary filtering resulted in 19 287 genes. Spatial distances between genes were based on the HiC experimental data of human lymphoblastoid cell line GM06990 (25). The 3D similarity matrices normalized by (26) were used. Removal of Tandem Duplicate Genes Duplicate ...
... unique position were kept. This preliminary filtering resulted in 19 287 genes. Spatial distances between genes were based on the HiC experimental data of human lymphoblastoid cell line GM06990 (25). The 3D similarity matrices normalized by (26) were used. Removal of Tandem Duplicate Genes Duplicate ...
Transcription in Eukaryotes Eukaryotes have 3 different RNA
... •Class II promoters have cis-acting DNA elements that influence transcription but are not part of the promoter: enhancers and silencers •Trans-acting factors - proteins - act in conjunction with cis-elements. •Enhancers stimulate transcription while silencers inhibit transcription. Certain elements ...
... •Class II promoters have cis-acting DNA elements that influence transcription but are not part of the promoter: enhancers and silencers •Trans-acting factors - proteins - act in conjunction with cis-elements. •Enhancers stimulate transcription while silencers inhibit transcription. Certain elements ...
Changing Patterns of Gene Regulation in the Evolution of Arthropod
... to ask, "What are the genetic changes underlying morphological diversity?" Beginning with an integrated functioning circuit in one organism, what are the possible ways in which you could modify it to produce a viable alternative? Are there particular types of changes that occur frequently and others ...
... to ask, "What are the genetic changes underlying morphological diversity?" Beginning with an integrated functioning circuit in one organism, what are the possible ways in which you could modify it to produce a viable alternative? Are there particular types of changes that occur frequently and others ...
Lecture 7 - Pitt CPATH Project
... • Assumption: there are recognizable signals in the DNA sequence that the cell uses; it should be possible to detect these algorithmically • Many programs designed to detect these signals • These programs do work to a certain extent, the information they provide is better than nothing; high error ra ...
... • Assumption: there are recognizable signals in the DNA sequence that the cell uses; it should be possible to detect these algorithmically • Many programs designed to detect these signals • These programs do work to a certain extent, the information they provide is better than nothing; high error ra ...
Chapter 18: Altering the Genetic Message
... from one location to another in the genome, using an enzyme to cut and paste themselves into new genetic neighborhoods. We call these mobile bits of DNA transposable elements, or transposons. Transposons select their new locations at random, and are as likely to enter one segment of a chromosome as ...
... from one location to another in the genome, using an enzyme to cut and paste themselves into new genetic neighborhoods. We call these mobile bits of DNA transposable elements, or transposons. Transposons select their new locations at random, and are as likely to enter one segment of a chromosome as ...
Genome Research 17
... genes than in autosomal genes. This “fast-X effect” should be evident by an increased ratio of nonsynonymous to synonymous substitutions (dN/dS) for sex-linked genes; however, recent studies have produced mixed support for this expectation. To make an independent test of the idea of fast-X evolution ...
... genes than in autosomal genes. This “fast-X effect” should be evident by an increased ratio of nonsynonymous to synonymous substitutions (dN/dS) for sex-linked genes; however, recent studies have produced mixed support for this expectation. To make an independent test of the idea of fast-X evolution ...
Expression analysis of a chicory fructan 1‐exohydrolase gene
... approach was used to clone the 1149 nt promoter fragment of FEHIIa (Michiels et al., 2003b). After obtaining the sequence for the HE-TAIL-PCR product, two gene-speci®c primers ±1149 HindIII-for (5¢-GTAAGCTTCGCAGACCTCTATCCATATATTAGTTC-3¢) and ATGKpnI-rev (5¢-AAAGGTACCTCTTCATGATGAGTGTGTGTGTTTGG-3¢) we ...
... approach was used to clone the 1149 nt promoter fragment of FEHIIa (Michiels et al., 2003b). After obtaining the sequence for the HE-TAIL-PCR product, two gene-speci®c primers ±1149 HindIII-for (5¢-GTAAGCTTCGCAGACCTCTATCCATATATTAGTTC-3¢) and ATGKpnI-rev (5¢-AAAGGTACCTCTTCATGATGAGTGTGTGTGTTTGG-3¢) we ...
Molecular studies on an ancient gene encoding
... Eukaryotic genes, as well as a small number of prokaryotic and organellar genes, have long intervening unexpressed sequences (introns) dividing the coding sequence into pieces (exons). The existence of introns in contemporary genomes has led to several mechanistic and historical questions. The debat ...
... Eukaryotic genes, as well as a small number of prokaryotic and organellar genes, have long intervening unexpressed sequences (introns) dividing the coding sequence into pieces (exons). The existence of introns in contemporary genomes has led to several mechanistic and historical questions. The debat ...
Patterns of gene action in plant development revealed by enhancer
... Downloaded from genesdev.cshlp.org on September 22, 2011 - Published by Cold Spring Harbor Laboratory Press ...
... Downloaded from genesdev.cshlp.org on September 22, 2011 - Published by Cold Spring Harbor Laboratory Press ...
Heterogeneity of Genome and Proteome Content in Bacteria
... activity, whereas archaea and bacteria share many ...
... activity, whereas archaea and bacteria share many ...
Simulating and cleaning gene expression data using
... is dependent on the goal of the analysis. We have developed a method, RUVNaiveRidge, for the removal of unwanted variation that focuses on retrieving the true underlying gene-gene correlations, but at the cost of the specification of the absolute values of gene expression (paper in preparation).The ...
... is dependent on the goal of the analysis. We have developed a method, RUVNaiveRidge, for the removal of unwanted variation that focuses on retrieving the true underlying gene-gene correlations, but at the cost of the specification of the absolute values of gene expression (paper in preparation).The ...
T - Crime Scene
... Several loci along our DNA have been identified as possessing STRs (thanks in part to the Human Genome Project), and the DNA profiling community has selected 13 regions for identity analysis These 13 loci ALL contain 4 nucleotide (tetrameric) repeats Through population studies, the numbers and types ...
... Several loci along our DNA have been identified as possessing STRs (thanks in part to the Human Genome Project), and the DNA profiling community has selected 13 regions for identity analysis These 13 loci ALL contain 4 nucleotide (tetrameric) repeats Through population studies, the numbers and types ...
MS Word document - Sequence Ontology
... whole. This debate arose when these two groups started to think about using SO for the types and relationships in their software. Promoter causes problems for these groups. They agree that the relationship between a promoter and a transcript is different from between an exon and a transcript. This i ...
... whole. This debate arose when these two groups started to think about using SO for the types and relationships in their software. Promoter causes problems for these groups. They agree that the relationship between a promoter and a transcript is different from between an exon and a transcript. This i ...
2000 Genome Biology paper
... The finding of the X-alignment pattern between species led us to search for similar patterns within species; that is, global alignments of a genome with its own reverse complement. Of the genomes for which we found between-species X-alignments (M. tuberculosis, M. leprae, S. pyogenes, S. pneumoniae, ...
... The finding of the X-alignment pattern between species led us to search for similar patterns within species; that is, global alignments of a genome with its own reverse complement. Of the genomes for which we found between-species X-alignments (M. tuberculosis, M. leprae, S. pyogenes, S. pneumoniae, ...
Prokaryotic Evolution in Light of Gene Transfer
... recombination are not necessary steps in their reproduction, unlike in the reproduction of complex eukaryotes. As a result, early models for understanding adaptation, evolution, and speciation in these organisms often focused on clonality and periodic selection (Levin 1981). According to such models ...
... recombination are not necessary steps in their reproduction, unlike in the reproduction of complex eukaryotes. As a result, early models for understanding adaptation, evolution, and speciation in these organisms often focused on clonality and periodic selection (Levin 1981). According to such models ...
Lecture 12 - U of L Class Index
... – Guide RNAs (gRNA) could direct the insertion and deletion of UMPs over a stretch of nucleotides in the mRNA – 5’-end of gRNA is complementary to the region of pre-mRNA that requires no editing; 3’-end directs the editing of premRNA. Editing starts at 3’-end of premRNA – When editing is done, the n ...
... – Guide RNAs (gRNA) could direct the insertion and deletion of UMPs over a stretch of nucleotides in the mRNA – 5’-end of gRNA is complementary to the region of pre-mRNA that requires no editing; 3’-end directs the editing of premRNA. Editing starts at 3’-end of premRNA – When editing is done, the n ...
Transposable element
A transposable element (TE or transposon) is a DNA sequence that can change its position within the genome, sometimes creating or reversing mutations and altering the cell's genome size. Transposition often results in duplication of the TE. Barbara McClintock's discovery of these jumping genes earned her a Nobel prize in 1983.TEs make up a large fraction of the C-value of eukaryotic cells. There are at least two classes of TEs: class I TEs generally function via reverse transcription, while class II TEs encode the protein transposase, which they require for insertion and excision, and some of these TEs also encode other proteins. It has been shown that TEs are important in genome function and evolution. In Oxytricha, which has a unique genetic system, they play a critical role in development. They are also very useful to researchers as a means to alter DNA inside a living organism.