
Understanding Evolutionary Relationships with
... sequence of the genes in each of these species are available for anyone in the world to access via the Internet. Why is this information important? Being able to identify the precise location and sequence of human genes will allow us to better understand genetic diseases. In addition, learning about ...
... sequence of the genes in each of these species are available for anyone in the world to access via the Internet. Why is this information important? Being able to identify the precise location and sequence of human genes will allow us to better understand genetic diseases. In addition, learning about ...
For the last three and a half billion years, evolution has been
... documentation represents the shared rules that allow the three databases to exchange data on a daily basis. The range of features to be represented is diverse, including regions which: perform a biological function, affect or are the result of the expression of a biological function, ...
... documentation represents the shared rules that allow the three databases to exchange data on a daily basis. The range of features to be represented is diverse, including regions which: perform a biological function, affect or are the result of the expression of a biological function, ...
Author`s personal copy
... Some bacteria are able to take up DNA from their general environment (transformation), including DNA that encodes resistance determinants. Resistance genes are rarely found in bacteriophages, but they can move DNA between cells (transduction), and their mechanisms for integration into host chromosom ...
... Some bacteria are able to take up DNA from their general environment (transformation), including DNA that encodes resistance determinants. Resistance genes are rarely found in bacteriophages, but they can move DNA between cells (transduction), and their mechanisms for integration into host chromosom ...
How Does Replication-Associated Mutational Pressure Influence
... Usually, DNA asymmetry analyses of genomes the W strand). In the T. pallidum genome, ∼60% of were performed on sliding windows. We have percoding sequences are located on the leading DNA formed detrended DNA walks for nucleotide composistrand. Because the walks in Figure 1a are presented in tion ana ...
... Usually, DNA asymmetry analyses of genomes the W strand). In the T. pallidum genome, ∼60% of were performed on sliding windows. We have percoding sequences are located on the leading DNA formed detrended DNA walks for nucleotide composistrand. Because the walks in Figure 1a are presented in tion ana ...
Bioinfo_primer_01
... • Molecular biology has handled on single genes and proteins, but now methods make it possible to operate on large sets simultaneously. • Information technology is an essential enabling technolgy(tool) in molecular biology. We know it as bioinformatics or biocomputing. • Bioinformatics is to a large ...
... • Molecular biology has handled on single genes and proteins, but now methods make it possible to operate on large sets simultaneously. • Information technology is an essential enabling technolgy(tool) in molecular biology. We know it as bioinformatics or biocomputing. • Bioinformatics is to a large ...
BMC Genomics
... Background: The increasing number of completely sequenced bacterial genomes allows comparing their architecture and genetic makeup. Such new information highlights the crucial role of lateral genetic exchanges in bacterial evolution and speciation. Results: Here we analyzed the twelve sequenced geno ...
... Background: The increasing number of completely sequenced bacterial genomes allows comparing their architecture and genetic makeup. Such new information highlights the crucial role of lateral genetic exchanges in bacterial evolution and speciation. Results: Here we analyzed the twelve sequenced geno ...
Antibiotic resistance genes are carried on plasmids
... nonchromosomal DNA. Like the nucleoid, the two ends of the doublestranded DNA molecule that make up a plasmid covalently bond together forming a physical circle. function: Plasmids code for synthesis of a few proteins not coded for by the nucleoid. For example, R-plasmids, found in some gram-negativ ...
... nonchromosomal DNA. Like the nucleoid, the two ends of the doublestranded DNA molecule that make up a plasmid covalently bond together forming a physical circle. function: Plasmids code for synthesis of a few proteins not coded for by the nucleoid. For example, R-plasmids, found in some gram-negativ ...
M-protein and other intrinsic virulence factors of Streptococcus
... Background: The increasing number of completely sequenced bacterial genomes allows comparing their architecture and genetic makeup. Such new information highlights the crucial role of lateral genetic exchanges in bacterial evolution and speciation. Results: Here we analyzed the twelve sequenced geno ...
... Background: The increasing number of completely sequenced bacterial genomes allows comparing their architecture and genetic makeup. Such new information highlights the crucial role of lateral genetic exchanges in bacterial evolution and speciation. Results: Here we analyzed the twelve sequenced geno ...
Expansion of tandem repeats and oligomer
... It is known that SSR constitute a large fraction of noncoding DNA and are relatively rare in protein coding sequences. SSR are of considerable practical and theoretical interest due to their high polymorphism [7]. The formation of a hairpin structure during replication [12,13] is believed to be the ...
... It is known that SSR constitute a large fraction of noncoding DNA and are relatively rare in protein coding sequences. SSR are of considerable practical and theoretical interest due to their high polymorphism [7]. The formation of a hairpin structure during replication [12,13] is believed to be the ...
1548 Tn Gene Is Borne by Composite Transposon Aminoglycoside
... Enterobacter cloacae, Escherichia coli, K. pneumoniae, Salmonella enterica, and Shigella flexneri, in which it was always associated with blaCTX-M-3 on an IncL/M plasmid. Conjugation, analysis of DNA sequences, PCR mapping, and plasmid conduction experiments indicated that the armA gene was part of ...
... Enterobacter cloacae, Escherichia coli, K. pneumoniae, Salmonella enterica, and Shigella flexneri, in which it was always associated with blaCTX-M-3 on an IncL/M plasmid. Conjugation, analysis of DNA sequences, PCR mapping, and plasmid conduction experiments indicated that the armA gene was part of ...
Lec 11 - Development of e
... controlled by a particular gene. Bateson and Punnett proposed the presence or absence theory. According to them, in a cross the character which dominates the other has a determiner, while, the recessive character has no such determiner. But all the theories were discarded by Morgan, who produced the ...
... controlled by a particular gene. Bateson and Punnett proposed the presence or absence theory. According to them, in a cross the character which dominates the other has a determiner, while, the recessive character has no such determiner. But all the theories were discarded by Morgan, who produced the ...
PDF
... in other species or Zizania-specific RNA-Seq data; 39 822 (81.8%) were found by homologs in the nr, InterProt, Swissprot and TrEMBL databases or functional classification using Gene Ontology (http://www.geneontology.org) and KEGG. To further validate the gene predictions, we used the predicted Z. la ...
... in other species or Zizania-specific RNA-Seq data; 39 822 (81.8%) were found by homologs in the nr, InterProt, Swissprot and TrEMBL databases or functional classification using Gene Ontology (http://www.geneontology.org) and KEGG. To further validate the gene predictions, we used the predicted Z. la ...
A deletion was detected on CGH microarray. The ISCN (2009)
... • Delineates deletions/ duplications more clearly – ‘what genes are in there?’ = more precise answer ...
... • Delineates deletions/ duplications more clearly – ‘what genes are in there?’ = more precise answer ...
PPT
... An important topic in microarray data mining is to bind transcriptionally modulated genes to functional pathways or how transcriptional modulation can be associated with specific biological events such as genetic disease phenotype, cell differentiation etc. However, the amount of functional annotati ...
... An important topic in microarray data mining is to bind transcriptionally modulated genes to functional pathways or how transcriptional modulation can be associated with specific biological events such as genetic disease phenotype, cell differentiation etc. However, the amount of functional annotati ...
Disease Genomics Part 2 - Medical Sciences Division
... (“virtual pull-down”). These are interaction partners for the candidate complex. (2) proteins known to be involved in disease are identified in the candidate complex, and pairwise scores of the phenotypic overlap between disease of these proteins and the candidate phenotype are assigned. (3) Based o ...
... (“virtual pull-down”). These are interaction partners for the candidate complex. (2) proteins known to be involved in disease are identified in the candidate complex, and pairwise scores of the phenotypic overlap between disease of these proteins and the candidate phenotype are assigned. (3) Based o ...
The Maintenance and Propagation of Plasmid Genes in Bacterial
... different plasmids, much of my detailed discussion will be confined to those that belong to the ColE1 family. These are small [S-10 kilobase pairs (kb)] plasmids present in multiple copies (20-40) per cell at cell division, and found in Escherichia coli and other enterobacteria (Sherratt et al., 197 ...
... different plasmids, much of my detailed discussion will be confined to those that belong to the ColE1 family. These are small [S-10 kilobase pairs (kb)] plasmids present in multiple copies (20-40) per cell at cell division, and found in Escherichia coli and other enterobacteria (Sherratt et al., 197 ...
A Hybrid Knowledge-Driver Approach to Clustering Gene
... The main limitation of many gene expression analytic approaches is the fact that they do not successfully incorporate domain knowledge about the genes into the actual process, compromising the quality of the results obtained. Once the clustering algorithm has terminated, the challenge is to validate ...
... The main limitation of many gene expression analytic approaches is the fact that they do not successfully incorporate domain knowledge about the genes into the actual process, compromising the quality of the results obtained. Once the clustering algorithm has terminated, the challenge is to validate ...
Gene Prediction
... genes based on statistical properties of the given DNA sequence. Programs are e.g. Genscan, GeneID, GENIE and FGENEH. Comparative methods: The given DNA string is compared with a similar DNA string from a different species at the appropriate evolutionary distance and genes are predicted in both sequ ...
... genes based on statistical properties of the given DNA sequence. Programs are e.g. Genscan, GeneID, GENIE and FGENEH. Comparative methods: The given DNA string is compared with a similar DNA string from a different species at the appropriate evolutionary distance and genes are predicted in both sequ ...
The Maintenance and Propagation of Plasmid Genes in Bacterial
... different plasmids, much of my detailed discussion will be confined to those that belong to the ColE1 family. These are small [S-10 kilobase pairs (kb)] plasmids present in multiple copies (20-40) per cell at cell division, and found in Escherichia coli and other enterobacteria (Sherratt et al., 197 ...
... different plasmids, much of my detailed discussion will be confined to those that belong to the ColE1 family. These are small [S-10 kilobase pairs (kb)] plasmids present in multiple copies (20-40) per cell at cell division, and found in Escherichia coli and other enterobacteria (Sherratt et al., 197 ...
nature | methods Versatile P[acman] BAC libraries for transgenesis
... and percentage of FlyBase R5.9 gene models spanned by P(acman) clones in the two BAC libraries, including 0 kb, 2 kb and 5 kb of additional sequence at the 5’ and 3’ ends of each model to account for unannotated transcribed and regulatory sequences, is shown. The redundancy of coverage of the genomi ...
... and percentage of FlyBase R5.9 gene models spanned by P(acman) clones in the two BAC libraries, including 0 kb, 2 kb and 5 kb of additional sequence at the 5’ and 3’ ends of each model to account for unannotated transcribed and regulatory sequences, is shown. The redundancy of coverage of the genomi ...
Thinking of Biology - Oxford Academic
... multicellular organism all have the same genes, but particular cell types express only some of them" (Epp Figure 1. Schematicrepresentationof some transcription, editing, and translation 1997, p. 537). He went on to say that processes, highlighting the context dependencyof the expression of gene pro ...
... multicellular organism all have the same genes, but particular cell types express only some of them" (Epp Figure 1. Schematicrepresentationof some transcription, editing, and translation 1997, p. 537). He went on to say that processes, highlighting the context dependencyof the expression of gene pro ...
Seed Germination Multiplexed Quantitative Gene Expression
... Slightly more variation was observed in the real time-qPCR analysis compared to the GeXP system. In our experience these differences between expression levels are not biologically significant and can easily arise from random variation inherent ...
... Slightly more variation was observed in the real time-qPCR analysis compared to the GeXP system. In our experience these differences between expression levels are not biologically significant and can easily arise from random variation inherent ...
Document
... • It can form a three-dimensional structure because of its ability to base-pair with itself • Some bases in RNA contain functional groups that may participate in catalysis • RNA may hydrogen-bond with other nucleic acid molecules ...
... • It can form a three-dimensional structure because of its ability to base-pair with itself • Some bases in RNA contain functional groups that may participate in catalysis • RNA may hydrogen-bond with other nucleic acid molecules ...
Adobe PDF - Boston University Physics
... of simple repeats is that they constitute a large fraction of noncoding DNA, but are relatively rare in protein coding sequences [3]. Another reason for the interest in simple sequence repeats is their possible relation to the long-range correlations found in DNA sequences: recent studies [4,5] supp ...
... of simple repeats is that they constitute a large fraction of noncoding DNA, but are relatively rare in protein coding sequences [3]. Another reason for the interest in simple sequence repeats is their possible relation to the long-range correlations found in DNA sequences: recent studies [4,5] supp ...
Distinct and stage specific nuclear factors regulate the expression of
... in erythrocyte invasion [2]. The transcriptome of intraerythrocytic developmental cycle (IDC) of PIasmodium falciparum thus resembles a "just-in-time" manufacturing process whereby transcripts are essentially produced when required. This concept has also been referred as "transcripts to go model" [3 ...
... in erythrocyte invasion [2]. The transcriptome of intraerythrocytic developmental cycle (IDC) of PIasmodium falciparum thus resembles a "just-in-time" manufacturing process whereby transcripts are essentially produced when required. This concept has also been referred as "transcripts to go model" [3 ...
Transposable element
A transposable element (TE or transposon) is a DNA sequence that can change its position within the genome, sometimes creating or reversing mutations and altering the cell's genome size. Transposition often results in duplication of the TE. Barbara McClintock's discovery of these jumping genes earned her a Nobel prize in 1983.TEs make up a large fraction of the C-value of eukaryotic cells. There are at least two classes of TEs: class I TEs generally function via reverse transcription, while class II TEs encode the protein transposase, which they require for insertion and excision, and some of these TEs also encode other proteins. It has been shown that TEs are important in genome function and evolution. In Oxytricha, which has a unique genetic system, they play a critical role in development. They are also very useful to researchers as a means to alter DNA inside a living organism.