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Genomics * Reading What we Can*t See
Genomics * Reading What we Can*t See

... The snippets of DNA were then lined up shortest to longest, and the color reflects the last base added (A, T, G, or C) ...
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... Vertebrates can live well without them: the puffer fish, for example, has a genome with very few of these repeats. In humans, most of them derive from transposable elements, parasitic stretches of DNA that replicate and insert a copy of themselves at another site. But now almost all the different fa ...
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... • Highly repetitive DNA is more abundant in larger genomes but there is no direct correlation between the amount of highly repetitive DNA and genome size. • Much of highly repetitive DNA in most species including humans, is present in the regions of chromosomes that flank the centromeres (centromeri ...
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... Epigenetics is also visibly at work when individuals survive famine. There have been several great famines in recorded history during which pregnant women survived and gave birth to apparently healthy offspring. Because the surviving mothers were forced to adapt to lowered food intake, they carried ...
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AP Biology Review Sheet for Chapters 18,19, and 20 Test (Test on

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... head form, how are the parts of a flower arranged • They are master switch genes which activate/regulate other genes needed for formation of body structures • Hox genes provide positional information in animal embryos ...
view PDF - Children`s Hospital of Wisconsin
view PDF - Children`s Hospital of Wisconsin

... determine all of our features such as eye color and hair color. Genes work by instructing cells to make proteins; it is the proteins that carry out the functions of the cell. Change in genes cause genetic disorders. For example, changes in one gene give rise to cystic fibrosis (CFTR) while changes ...
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Genomics - FSU Biology - Florida State University
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The Genetics of Bacteria and Their Viruses

... • Bacteria contain a wide variety of transposable elements (as do all other organisms studied to date) • The smallest and simplest are insertion sequences, or IS elements, which are 1–3 kb in length and encode the transposase protein required for transposition and one or more additional proteins tha ...
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Epigenetics 101 - Nationwide Children`s Hospital

... make an imprint on genes, that can then be passed from one generation to the next ...
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Introduction to Next-Generation Sequence analysis

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Complementary DNA Sequencing: Expressed Sequence Tags and

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Post-transcriptional Gene Silencing (PTGS)
Post-transcriptional Gene Silencing (PTGS)

... • Theory: by introducing an antisense gene (or asRNA) into cells, the asRNA would “zip up” the complementary mRNA into a dsRNA that would not be translated • The “antisense effect” was highly variable, and in light of the discovery of RNAi, asRNA probably inhibited its target by inducing RNAi rather ...
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- Cal State LA - Instructional Web Server

... City of Hope Dr. Steven Smith Dr. Kristofer Munson Dr. Jarrod Clark Dr. Taras Schevchuck ...
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Transposable element



A transposable element (TE or transposon) is a DNA sequence that can change its position within the genome, sometimes creating or reversing mutations and altering the cell's genome size. Transposition often results in duplication of the TE. Barbara McClintock's discovery of these jumping genes earned her a Nobel prize in 1983.TEs make up a large fraction of the C-value of eukaryotic cells. There are at least two classes of TEs: class I TEs generally function via reverse transcription, while class II TEs encode the protein transposase, which they require for insertion and excision, and some of these TEs also encode other proteins. It has been shown that TEs are important in genome function and evolution. In Oxytricha, which has a unique genetic system, they play a critical role in development. They are also very useful to researchers as a means to alter DNA inside a living organism.
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