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Sex & Death: Introduction to the Philosophy of Biology
Sex & Death: Introduction to the Philosophy of Biology

... • Disadvantage of viewing genes as ‘difference makers’ is that it becomes unclear whether they have an independent reality as a gene ...
Ch19EukaryoticGeneControl - Environmental
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families and function.pptx

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... Results in a contig library with ~97% genome coverage (the missing 3% is composed mostly of repeated DNA sequence). ...
lytic cycle - Cloudfront.net
lytic cycle - Cloudfront.net

... FROM THE SURROUNDING ENVIRONMENT, THE BACTERIUM NO LONGER NEEDS TO MAKE ITS OWN TRYPTOPHAN. IN THIS CASE, RISING LEVELS OF TRPTOPHAN INDUCE SOME TRYPTOPHAN TO REACT WITH THE INACTIVE REPRESSOR AND MAKE IT ACTIVE. HERE TRPTOPHAN IS ACTING AS A COREPRESSOR. THE ACTIVE REPRESSOR NOW BINDS TO THE OPERAT ...
BioSc 231 Exam 5 2005
BioSc 231 Exam 5 2005

... A. chromosomal DNA which has been isolated from a donor organism. B. complementary DNA that is generated by using reverse transcriptase to make DNA from mRNA. C. cloned DNA that has been introduced into a cloning vector. D. cut DNA that has been digested with a restriction endonuclease for use in a ...
What is a gene?
What is a gene?

... Transcription factors, defined here specifically as proteins containing domains that suggest sequencespecific DNA-binding activities, are classified based on the presence of 50+ conserved domains. Links to resources that provide information on mutants available, map positions or putative functions f ...
The Secret of How Life Works - The Biotechnology Institute
The Secret of How Life Works - The Biotechnology Institute

... the right recipe, it starts to read it. It chugs down the long DNA chain like a train on a track. When it meets a stop sign (stop codon), it has reached the end of the recipe. This DNA track is made of four chemical bases—adenine, cytosine, guanine, and thymine—which are known by their initials A, C ...
protein processing
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... Due only to COMBINATORIAL diversity In practice, some H + L combinations do not occur as they are unstable Certain V and J genes are also used more frequently than others. There are other mechanisms that add diversity at the junctions between genes - JUNCTIONAL diversity GENERATES A POTENTIAL B-CELL ...
Lecture#7 - Eukaryote gene structure and regulation.
Lecture#7 - Eukaryote gene structure and regulation.

... The biochemistry of intron splicing is well understood and involves the lariat model. For some genes (most) the processed mature mRNA is the same product each time. ...
ab initio - Ware Lab
ab initio - Ware Lab

... From its domestication 8,000 years ago in Central America to its position today as the world’s leading harvested grain, Zea mays has played an important role in human civilization, providing food, animal feed, and biofuel. Maize also enjoys a long and distinguished history as a model organism owing ...
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... In this lab, the microarray used is a commercial gene chip. Each spot on the slide (or microarray) is a single stranded DNA sequence from a different human gene. Scientists originally used a gene chip that contained 6,187 genes, one gene per spot. In the minimicroarray you view in this activity, the ...
Intelligent DNA Chips: Logical Operation of Gene Expression
Intelligent DNA Chips: Logical Operation of Gene Expression

... 4. DCN seqs are simultaneously applied to a DNA chip with DNA strands encoding Boolean formulae 5. The complementary marker sequences fluorescently tagged are applied to the DNA chip after the logical evaluation and annealed to marker in the DNA chip which remain single-stranded. 6. * Color: truth-v ...
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... Objection #2: Why Sequence the Junk? • ~2% of the human genome codes for polypeptides, – why not sequence the 6o million bases that “make something”. ...
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... Objection #2: Why Sequence the Junk? • ~2% of the human genome codes for polypeptides, – why not sequence the 6o million bases that “make something”. ...
Creating mutant flies
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Using Data from the Human Genome Project in
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... too demanding for most high school students, tools used to access the data have improved to the point where they can easily be used by students. This past Spring, I used a "scavenger hunt" approach to the Genome for students in my college freshman biology classes at Brown. I've modified the approach ...
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Learning objectives: • Define the terms `Gene` and `Chromosome

... !  Genes act as ...
SMCarr passport for UPS
SMCarr passport for UPS

... function, but the expanded alleles are dominant and the normal alleles are recessive. ›  ??? Underlying cause unknown, but may be due to abnormal protein products coded by the TNE genes = form insoluble aggregates within nerve cells. 2.  Haploinsufficiency: Heterozygote phenotype; ~50% reduction in ...
Evolution of genomes
Evolution of genomes

... Mutations on a global scale On the scale of the whole genome, several types of mutations are known to have occurred. For our purposes, the most interesting phenomena are gene duplications and genome rearrangements. Another important effect of evolution on a global scale is the existence of highly r ...
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Transposable element



A transposable element (TE or transposon) is a DNA sequence that can change its position within the genome, sometimes creating or reversing mutations and altering the cell's genome size. Transposition often results in duplication of the TE. Barbara McClintock's discovery of these jumping genes earned her a Nobel prize in 1983.TEs make up a large fraction of the C-value of eukaryotic cells. There are at least two classes of TEs: class I TEs generally function via reverse transcription, while class II TEs encode the protein transposase, which they require for insertion and excision, and some of these TEs also encode other proteins. It has been shown that TEs are important in genome function and evolution. In Oxytricha, which has a unique genetic system, they play a critical role in development. They are also very useful to researchers as a means to alter DNA inside a living organism.
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