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PowerPoint-Präsentation
PowerPoint-Präsentation

... progress towards efficient gene isolation and genomic sequencing in barley Mission statement Barley (Hordeum vulgare L.) was one of the first domesticated cereal grains, originating in the Fertile Crescent over 10,000 years ago. Barley ranks fifth in worldwide crop production and is widely cultivate ...
Lecture 27
Lecture 27

... to the cytoplasm. These processes are coupled in the nucleus so that only properly processed mRNAs are exported to the cytoplasm •The role of introns is still controversial but the favored hypothesis is that they arose early in evolution and allowed recombination between mini-genes. They have been a ...
LETTER Insertion DNA Promotes Ectopic Recombination during
LETTER Insertion DNA Promotes Ectopic Recombination during

... DNAs that are comprised of one or more gene members may act as ‘‘bridges’’ to homogenize nucleotide diversity among nonallelic members. On the other hand, exchange events of genetic information from nonallelic locations will introduce novel nucleotide variations into new loci. An asymmetric arrangem ...
Large-Scale High-Resolution Orthology Using Gene Trees
Large-Scale High-Resolution Orthology Using Gene Trees

... and Orthology Two genes in two species are orthologous if they derive from one gene in their last common ancestor • Orthologous genes are likely to have the same function • Much stronger than “tend to have similar function” ...
Review-Session-8-Pseudoallelism
Review-Session-8-Pseudoallelism

... Bx is an enhancer that causes expression of Ubx at the anterior part of T3. pbx is an enhancer that causes expression Ubx of the posterior part of T3. What would the following heterozygotes from the complementation test look like? ubx/ bx: anterior part of the haltere is now a wing ubx/pbx: posterio ...
Supplementary methods
Supplementary methods

... pair identity. This mRNA encodes the PSG4 (pregnancy specific beta-1-glycoprotein 4) gene that is annotated as containing two immunoglobulin C-2 type regions, thus the reduced base pair identity is most likely due to haplotype differences. The RefSeq mRNA for this locus, NM_002780, aligns at nearly ...
genome - Microme
genome - Microme

... TrEMBL contains functional annotations which often come from automatic procedures only: ‘IPMed?’ is used for proteins that may have an experimentally validated function. ...
View ePoster - 2015 AGU Fall Meeting
View ePoster - 2015 AGU Fall Meeting

... methyl-coenzyme M reductase alpha subunit (mcrA). PmoA genes of Type II methanotrophs were found three times more than Type I methanotrophs. A pmoA gene sequence represents 42% of the library matches only and is identical to a putative protein sequence annotated on Ca. D. audaxviator genome, but fur ...
Text S1. Predicted Functional RNAs Within Coding Regions
Text S1. Predicted Functional RNAs Within Coding Regions

... were determined as described with the “Saccharomyces cerevisae Gene Annotation”. EvoFold predictions from the phastCons blocks were then screened using the RNAz program [6]. These two programs make predictions in fundamentally different ways (see Table S3 and Figures S1-S3). To objectively determine ...
Permanent draft genome of Thermithiobaclillus tepidarius DSM
Permanent draft genome of Thermithiobaclillus tepidarius DSM

... gene libraries from the Roman Baths and have isolated a number of strains to date, indicating that Thermithiobacillus spp. are no more difficult to isolate than other sulfur-oxidising autotrophs and may thus simply be rare or confined to rare ecosystems. It forms white colonies of 2–5 mm diameter in ...
Designing Molecular Machines·
Designing Molecular Machines·

... of the sequence of a disease-causing gene without knowing where the gene is. This is because genes are the blueprints for proteins, and if an aberrant or malfunctioning protein can be tied to a disease, then biologists can work backward from the protein to deduce what the gene looked like that gave ...
Document
Document

... Seeks to achieve a mutual understanding of the definition and meaning of any word used. thus we are able to support cross-database queries. Members agree to provide database access via these common terms to gene product annotations and associated sequences. TJL-2004 ...
Genes and causation
Genes and causation

... Crick’s work, has succeeded brilliantly in mapping sequences of DNA to those of amino acids in proteins, but not in explaining phenotype inheritance. Whether we start from DNA or protein sequences, the question is still there. It lies in the complexity of the way in which the DNA and proteins are us ...
Tracing Our Unicellular Ancestors Tracing Our
Tracing Our Unicellular Ancestors Tracing Our

... indeed have observed some type of differentiation in C. owczarzaki, such as “the formation of resistant cystic cells, alternating with its common phase as an amoeboid adhered to substrate and with multiple filopodia”. Alex de Mendoza, the other first author of the paper and also a PhD student with R ...
The ATM repair pathway inhibits RNA polymerase I transcription in
The ATM repair pathway inhibits RNA polymerase I transcription in

... when and how much of a gene product will be produced. ...
Five Genes Help Form a Face
Five Genes Help Form a Face

... nine landmarks on the face. The distances between different pairs of landmarks in a given face were traits for the team to evaluate—for example, the spacing between the eyes or the distance from the tip of the nose to its base Live Chat: New Treasures in the Genome Thursday 3 p.m. EDT As part of the ...
Genome Organization
Genome Organization

... particular, through movement of transposable elements. • Evidence is accumulating for the importance of lateral transfer in fungi, animal, and plant evolution. ...
Organisation of the human genome and our tools for
Organisation of the human genome and our tools for

... other polypeptides, the functional endpoint of this process: the protein. As stated earlier, as a result of the variation produced during evolution the size of the genome (and our genes) has expanded compared with more simple organisms. Only 2% of the DNA sequence information in the human genome is ...
news story - Cambridge Machine Learning Group
news story - Cambridge Machine Learning Group

... easier said than done. To cure it, you have to know how it works. To do that, you have to understand what makes malaria parasites similar to or different from one another. And to achieve that, you have to know where to look. Which takes us from the world’s worst malaria hotspots to the unlikely sett ...
Communication
Communication

...  Cut out of chromosomes  Made by “reverse transcription” of mRNA ...
Complete genome sequence of an M1 strain of Streptococcus
Complete genome sequence of an M1 strain of Streptococcus

... genomes present on one side. A replication termination protein and ter site have not been identified at this time. However, a putative dif-like termination sequence, identical to that found in many bacteria, including Escherichia coli, is found starting at base pair 929,320, roughly at the point opp ...
The Map-based Sequence of the Rice Genome
The Map-based Sequence of the Rice Genome

... the fully sequenced dicot plant model Arabidopsis thaliana. We generated 370 Mb of finished sequence, representing 95% coverage of the genome and virtually all of the euchromatic regions, as listed in Table 1. * A total of 37,544 non-transposable-element-related protein-coding sequences were detecte ...
Bioprospecting of Genes and Allele Mining
Bioprospecting of Genes and Allele Mining

... bio-prospecting began when prehistoric people noticed that one plant root tasted better than another, or some plants could be used as medicines to treat various human diseases. ...
TRPGR: Sequencing the barley gene-space
TRPGR: Sequencing the barley gene-space

... in the US commitment to the international effort to physically map and sequence the barley “gene space”. Another important preliminary step towards sequencing the large genome of barley is to obtain a glimpse to the genome structure and how it compares to other related sequenced genomes. As barley i ...
Biological Basis for Gene Hunting
Biological Basis for Gene Hunting

... 4 A phenomenon related to transposition is the mobile genetic element or transposon first described by Barbara McClintock in 1950. ...
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Transposable element



A transposable element (TE or transposon) is a DNA sequence that can change its position within the genome, sometimes creating or reversing mutations and altering the cell's genome size. Transposition often results in duplication of the TE. Barbara McClintock's discovery of these jumping genes earned her a Nobel prize in 1983.TEs make up a large fraction of the C-value of eukaryotic cells. There are at least two classes of TEs: class I TEs generally function via reverse transcription, while class II TEs encode the protein transposase, which they require for insertion and excision, and some of these TEs also encode other proteins. It has been shown that TEs are important in genome function and evolution. In Oxytricha, which has a unique genetic system, they play a critical role in development. They are also very useful to researchers as a means to alter DNA inside a living organism.
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