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supervised-i
supervised-i

... Neighbors within distance d get to vote (no matter how many there are) distance = d ...
The HAT2 Homeodomain-Like Transcription Factor Family
The HAT2 Homeodomain-Like Transcription Factor Family

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Mendelian Genetics - Marion County Public Schools
Mendelian Genetics - Marion County Public Schools

... meiosis. Result is missing or extra chromosomes attached where they should not be. One example is Down’s syndrome (nondisjunction of chromosome #21) 4. Disjunction - separation of the chromosomes, although not always accurately, which can also lead to genetic defects. ** If disjunction fails to occu ...
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Canadian Journal of Microbiology

... on indicator plates containing X-Gal (5-bromo-4-chloro-3indolyl-β-D-galactopyranoside) and IPTG (isopropyl-β-Dthiogalactopyranoside), were picked, resuspended in 80 µL of Tris–EDTA buffer, and boiled for 10 min. Subsequently, cells were centrifuged for 5 min at 13 700g, and supernatants (1 µL) were ...
DNA Replication
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Recombinant DNA Technology

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Phage
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Biochemical and functional characterization of Plasmodium

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results and discussion discussion

... 4.3 SCREENING OF METAGENOMIC LIBRARY FOR SALT TOLERANT CLONES Gene enrichment strategies have been used to target the active salt tolerance clones from pond water microbial community. Enriched in LB ampicillin broth and 4%, 5% or 6% NaCl, the amplified pond water metagenomic library clones were sele ...
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Molecular Cloning, Sequencing, and Expression of the Glutamine

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Effects of Genic Base Composition on Growth Rate in G+C

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GRADE 11F: Biology 4
GRADE 11F: Biology 4

... Assuming this DNA was coding for an enzyme, discuss the possible outcome of this base change with students. For example, the incorrect amino acid in the protein may result in the incorrect shape of the active site of the enzyme. (The tertiary shape of the protein/enzyme may be altered: see Unit 10FB ...
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STEM-ED Genetics pathway

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Arabinose induction - Olympic High School Home Page
Arabinose induction - Olympic High School Home Page

... Questions about procedure • What is meant by a “control plate”? • What purpose does a control serve? ...
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Genomic library



A genomic library is a collection of the total genomic DNA from a single organism. The DNA is stored in a population of identical vectors, each containing a different insert of DNA. In order to construct a genomic library, the organism's DNA is extracted from cells and then digested with a restriction enzyme to cut the DNA into fragments of a specific size. The fragments are then inserted into the vector using DNA ligase. Next, the vector DNA can be taken up by a host organism - commonly a population of Escherichia coli or yeast - with each cell containing only one vector molecule. Using a host cell to carry the vector allows for easy amplification and retrieval of specific clones from the library for analysis.There are several kinds of vectors available with various insert capacities. Generally, libraries made from organisms with larger genomes require vectors featuring larger inserts, thereby fewer vector molecules are needed to make the library. Researchers can choose a vector also considering the ideal insert size to find a desired number of clones necessary for full genome coverage.Genomic libraries are commonly used for sequencing applications. They have played an important role in the whole genome sequencing of several organisms, including the human genome and several model organisms.
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