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... is higher after drug treatment Red -- expression of the gene is lower after drug treatment ...
16. Nuclear gene organization
16. Nuclear gene organization

...  snRNAs: small nuclear RNAs involved in pre-mRNA splicing o i.e. U1, U2, U4, U6 snRNAs  snoRNAs: small nucleolar RNAs involved in rRNA processing  many other genes 3. Gene families  most genes code for proteins  most genes contain introns, some do not o histones, interferons, heat shock protein ...
Bacterial Comparative Genomics
Bacterial Comparative Genomics

... • When you ask, does strain A have gene X?... • What you are really asking is, does strain A have an ortholog of gene X? (where gene X is characterized in another strain) • If two genes are orthologs, that does not imply they have same function, but they often do • If two genes are paralogs, they ha ...
Lecture-TreeOfLife
Lecture-TreeOfLife

... Fig. 1. Two methods for assessing LGT in bacterial genomes, applied to available quartets of closely related, fully sequenced bacterial taxa. The reference topology, based on SSU rRNA, is shown in the upper left, with taxon names listed in the rows below. The yellow box contains the numbers of gen ...
Ghost in Your Genes Response
Ghost in Your Genes Response

... IB Biology NOVA: Ghost in Your Genes ...
Abstract - Anil Jegga - Cincinnati Children`s Hospital
Abstract - Anil Jegga - Cincinnati Children`s Hospital

pdf format publicity flyer for the proceedings
pdf format publicity flyer for the proceedings

... Chloroplasts and mitochondria are energy-converting organelles of eukaryotic cells. They also contain small, specialised, functional genomes. While their genetic and energy-converting systems are evidently bacterial in origin, most genes for chloroplast and mitochondrial components now reside in the ...
In situ - University of Evansville Faculty Web sites
In situ - University of Evansville Faculty Web sites

... • Consecutive high-resolution genetic and physical maps culminate in the complete DNA sequence. • Sequencing strategies depend upon the size of the genome and the distribution of its repetitive sequences. • Assembly of sequences is done clone by clone or by whole genome assembly, or both. • Computat ...
Concept Check Questions with answers
Concept Check Questions with answers

... programs that identify overlapping regions. ...
In situ - University of Evansville Faculty Web sites
In situ - University of Evansville Faculty Web sites

... • Consecutive high-resolution genetic and physical maps culminate in the complete DNA sequence. • Sequencing strategies depend upon the size of the genome and the distribution of its repetitive sequences. • Assembly of sequences is done clone by clone or by whole genome assembly, or both. • Computat ...
II. Transposable Elements in Bacteria Transposable Elements are
II. Transposable Elements in Bacteria Transposable Elements are

... events that may lead to DNA deletions, sequence inversions, or fusion of separate DNA molecules. For example, homologous recombination between copies of the same IS element in a conjugal plasmid and the bacterial chromosome leads to formation of Hfr strains, as shown below. ...
doc - FSU Biology
doc - FSU Biology

... Prokaryotic Biology; MCB 4403 ...
450 Mbp genome of rice, Oryza sativa
450 Mbp genome of rice, Oryza sativa

... contributed to this effort, including two large companies, Syngenta and Monsanto, who produced WGS drafts, a WGS draft by a Chinese genome center, and detailed clone-by-clone efforts by the Japanese. Several conclusions are worth noting: A. Despite about at least 200 Myr divergence between these two ...
Slide 1
Slide 1

... • #1: Students design and perform experiments, make observations, formulate hypothesis about identity of unknowns, and predict gene content • #2: Statistical analysis, such as bootstrapping in phylogenetic tree construction; requires quantitative reasoning • #3: Compare phylogenetic trees with those ...
Institute for Animal Health
Institute for Animal Health

... Institute for Animal Health Comparative analyses ...
Bioinformatics - Oxford Academic
Bioinformatics - Oxford Academic

ISVEE/181 Molecular characterization of indigenous peste des petits
ISVEE/181 Molecular characterization of indigenous peste des petits

... Pakistan1National Veterinary Laboratory, Islambad, Pakistan ...
MEDG505.Yeast.testbed.05
MEDG505.Yeast.testbed.05

... • Testbed for genomic technologies – Genome sequenced (4/96) relatively less complex – Ability to assess biological relevance of the data ...
Gene Hunting
Gene Hunting

... Vibrio cholerae recovered directly from patient specimens • Methodology ...
BINF6201/8201: Molecular Sequence Analysis
BINF6201/8201: Molecular Sequence Analysis

Rapid Evolution in the Human Genome
Rapid Evolution in the Human Genome

... lineage-specific evolution: a phylogenetic hidden Markov model (phylo-HMM) and a likelihood ratio test (LRT). The phylo-HMM works well for identifying relatively ancient events, while the LRT is much more powerful at the leaves of a phylogeny (e.g. the human lineage). Using this LRT, we identified 2 ...
Slide 1
Slide 1

... 1. Washington State University, 2. Cotton Incorporated, 3. USDA-ARS ...
Genomic and gene expression profiling in malignant hematology
Genomic and gene expression profiling in malignant hematology

... assays in malignant hematology. Microarrays are high throughput tools that have evolved during the past decade. These allow for dissection of all known genes in malignant cells at genomic or transcriptional level in a single experiment. The human genome contains approximately 23,000 protein-coding g ...
Assembling and Annotating the Draft Human Genome
Assembling and Annotating the Draft Human Genome

... – Being inserted from another chromosome since dog/human common ancestor (breaking synteny). – High rate of mutation (Ka/Ks ratio). • Robert Baertsch at UCSC has produced a processed ...
Genomic Annotation
Genomic Annotation

... Only ~15% of known mammalian genes have 1 exon Many pseudogenes are mRNA’s that have been retro-transposed back into the genome; many of these will appear as single exon genes Increase vigilance for signs of a pseudogene for any single exon gene Alternatively, there may be missing exons ...
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Pathogenomics

Pathogen infections are among the leading causes of infirmity and mortality among humans and other animals in the world. Until recently, it has been difficult to compile information to understand the generation of pathogen virulence factors as well as pathogen behaviour in a host environment. The study of Pathogenomics attempts to utilize genomic and metagenomics data gathered from high through-put technologies (e.g. sequencing or DNA microarrays), to understand microbe diversity and interaction as well as host-microbe interactions involved in disease states. The bulk of pathogenomics research concerns itself with pathogens that affect human health; however, studies also exist for plant and animal infecting microbes.
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