Prospective diagnostic analysis of copy number variants using SNP
... healthy individuals, de novo occurrence and/or presence in previously reported syndromes associated with ID and ASD: a de novo triplication of the 15q11–q12 region in a male subject (family 772), a deletion of the 9p24 region in a female (family 15) and a deletion of 3q29 in a male (family 1315) (Fi ...
... healthy individuals, de novo occurrence and/or presence in previously reported syndromes associated with ID and ASD: a de novo triplication of the 15q11–q12 region in a male subject (family 772), a deletion of the 9p24 region in a female (family 15) and a deletion of 3q29 in a male (family 1315) (Fi ...
the evolution of genomic base composition in bacteria
... model to describe the evolution of GC content over time. A Brownian-motion model describes a random walk in continuous time over a continuous state space, where future states depend only on the current state of the system (Taylor and Karlin 1998). In mathematical terms, we assume that GC content fol ...
... model to describe the evolution of GC content over time. A Brownian-motion model describes a random walk in continuous time over a continuous state space, where future states depend only on the current state of the system (Taylor and Karlin 1998). In mathematical terms, we assume that GC content fol ...
Further genetic evidence suggesting a role for the
... Osteoporosis is a highly heritable trait that appears to be influenced by multiple genes. Genome-wide linkage studies have highlighted the chromosomal region 3p14-p21 as a quantitative trait locus for BMD. We have previously published evidence suggesting that the ARHGEF3 gene from this region is asso ...
... Osteoporosis is a highly heritable trait that appears to be influenced by multiple genes. Genome-wide linkage studies have highlighted the chromosomal region 3p14-p21 as a quantitative trait locus for BMD. We have previously published evidence suggesting that the ARHGEF3 gene from this region is asso ...
Hd6, a rice quantitative trait locus involved in photoperiod
... series of genes and show continuous variation in progeny. Many efforts have been made to map such genes, known as quantitative trait loci (QTLs), because of their biological and agronomic importance. The development of a high-density linkage map based on DNA markers made it possible to map QTLs with ...
... series of genes and show continuous variation in progeny. Many efforts have been made to map such genes, known as quantitative trait loci (QTLs), because of their biological and agronomic importance. The development of a high-density linkage map based on DNA markers made it possible to map QTLs with ...
REVIEW ARTICLE Gene cassettes
... account for a significant proportion of the antibioticresistance genes found in Gram-negative bacteria of the Enterobacteriaceae family and the genus Psezldomonas. For most antibiotics, several quite distinct resistance genes are found, and in some cases the mechanism by which resistance is conferre ...
... account for a significant proportion of the antibioticresistance genes found in Gram-negative bacteria of the Enterobacteriaceae family and the genus Psezldomonas. For most antibiotics, several quite distinct resistance genes are found, and in some cases the mechanism by which resistance is conferre ...
Structural and Functional Studies of Insertion Element IS200
... The nucleotide sequence of the insertion element 15200 has been determined partially, including the junctions between the element and the host chromosome at the insertion site, At most, two bases (A-A) are found repeated at the junctions and could be duplications of host sequences generated by the i ...
... The nucleotide sequence of the insertion element 15200 has been determined partially, including the junctions between the element and the host chromosome at the insertion site, At most, two bases (A-A) are found repeated at the junctions and could be duplications of host sequences generated by the i ...
Ribosome Profiling
... technique has been developed, known as Ribosome profiling (RP). RP is defined as a genome wide mapping of nucleotides on mRNA occupied by ribosomes during translation at a specific time. Generally polysome profiling is used to distinguish mRNA molecules involved in active translation from the non-tr ...
... technique has been developed, known as Ribosome profiling (RP). RP is defined as a genome wide mapping of nucleotides on mRNA occupied by ribosomes during translation at a specific time. Generally polysome profiling is used to distinguish mRNA molecules involved in active translation from the non-tr ...
PPTX - Bioinformatics.ca
... • To test for under-enrichment of “black”, test for overenrichment of “red”. • The EASE score used by DAVID subtracts one from the observed overlap between gene list and gene set to ensure >1 from the list is in the gene set. • Need to choose “background population” appropriately, e.g., if only port ...
... • To test for under-enrichment of “black”, test for overenrichment of “red”. • The EASE score used by DAVID subtracts one from the observed overlap between gene list and gene set to ensure >1 from the list is in the gene set. • Need to choose “background population” appropriately, e.g., if only port ...
Genetics of Bacteriophage P22. II. Gene Order and Gene Function.
... tests are nearly useless; liquid tests have been carried out on many combinations of mutants in these genes. The method is exactly the same as the standard cross (see below) except that an appropriate nonpermissive host is used. In cases involving ts mutants, the test is carried out at 40 °. In most ...
... tests are nearly useless; liquid tests have been carried out on many combinations of mutants in these genes. The method is exactly the same as the standard cross (see below) except that an appropriate nonpermissive host is used. In cases involving ts mutants, the test is carried out at 40 °. In most ...
Journal of Bacteriology
... plant products as well as the R. trifolii nodDABC genes, which are functionally exchangeable with those of R. leguminosarum (3, 4, 19), were required for the production of these factors. Remarkably, autoclaved supernatant fluids of very dense cultures of a Sym plasmid-cured R. trifolii strain induce ...
... plant products as well as the R. trifolii nodDABC genes, which are functionally exchangeable with those of R. leguminosarum (3, 4, 19), were required for the production of these factors. Remarkably, autoclaved supernatant fluids of very dense cultures of a Sym plasmid-cured R. trifolii strain induce ...
The Ubiquitous Nature of Epistasis in Determining Susceptibility to
... all transcriptional complexes. The third group is comprised of proteins that interact with activators and repressors to enhance their effects. As discussed by Martinez [2002], it is cooperative protein-protein and protein-DNA interactions that are critical for the regulation of transcription by pro ...
... all transcriptional complexes. The third group is comprised of proteins that interact with activators and repressors to enhance their effects. As discussed by Martinez [2002], it is cooperative protein-protein and protein-DNA interactions that are critical for the regulation of transcription by pro ...
PersPecTIves - Ralf Sommer
... One reverse genetics technology that has been used extensively in evo–devo in recent years to overcome technical limitations is RNAi. Although RNAi is becoming increasingly accessible, it is not easily transferable to every organism, and even in C. elegans, in which it was originally described, it d ...
... One reverse genetics technology that has been used extensively in evo–devo in recent years to overcome technical limitations is RNAi. Although RNAi is becoming increasingly accessible, it is not easily transferable to every organism, and even in C. elegans, in which it was originally described, it d ...
based methods in the environment and hospital patients
... • 56% of isolates were MRSA & represented ITS- types 1,3,4,5,16 & 17. Screen for these? • ITS-type 6 predominated clinical samples with MRSA representatives found in both environmental isolates and environmental samples. Screen for these also? • Different ITS-types were colonizing the environment co ...
... • 56% of isolates were MRSA & represented ITS- types 1,3,4,5,16 & 17. Screen for these? • ITS-type 6 predominated clinical samples with MRSA representatives found in both environmental isolates and environmental samples. Screen for these also? • Different ITS-types were colonizing the environment co ...
Genomic Sequence Data - G3: Genes | Genomes | Genetics
... the sequencing of novel viral genomes from metagenomic datasets and the targeted assembly of genes-of-interest from whole-genome datasets. The motivation for PRICE was to facilitate the assembly of individual genomes of interest using complex, shotgun, metagenomic datasets, derived from virtually a ...
... the sequencing of novel viral genomes from metagenomic datasets and the targeted assembly of genes-of-interest from whole-genome datasets. The motivation for PRICE was to facilitate the assembly of individual genomes of interest using complex, shotgun, metagenomic datasets, derived from virtually a ...
Annotation mapping functions
... Are you surprised about the result? The four arguments pre.from, pre.to, post.from and post.to corresponds directly to the from and to arguments in translate, with ”pre” for the translation before mapping and ”post” for the translation after mapping. In this example we used the org.Hs.eg.db to map t ...
... Are you surprised about the result? The four arguments pre.from, pre.to, post.from and post.to corresponds directly to the from and to arguments in translate, with ”pre” for the translation before mapping and ”post” for the translation after mapping. In this example we used the org.Hs.eg.db to map t ...
Origin and Distribution of Calvin Cycle Fructose and
... could be the active holoenzyme; however, post-translational processing cannot be ruled out. ...
... could be the active holoenzyme; however, post-translational processing cannot be ruled out. ...
Analyzing microRNA Data and Integrating microRNA with Gene
... For this tutorial, microRNA from 3 brain samples and 3 heart samples were quantified using the Affymetrix GeneChip® miRNA 1.0 array. The same sample set was also processed on GeneChip® Human Gene 1.0 ST arrays for mRNA expression. Data and associated files for this tutorial can be downloaded by sele ...
... For this tutorial, microRNA from 3 brain samples and 3 heart samples were quantified using the Affymetrix GeneChip® miRNA 1.0 array. The same sample set was also processed on GeneChip® Human Gene 1.0 ST arrays for mRNA expression. Data and associated files for this tutorial can be downloaded by sele ...
Introduction: - Statistical Science
... optimistic results when assessing significance. This may lead to too many sets passing an FDR cutoff of 0.25. For example, the table shows the differences between phenotype label and gene tag permutations for the Gender dataset example. The large number of gene sets passing the test using gene tag p ...
... optimistic results when assessing significance. This may lead to too many sets passing an FDR cutoff of 0.25. For example, the table shows the differences between phenotype label and gene tag permutations for the Gender dataset example. The large number of gene sets passing the test using gene tag p ...