A unique pattern of intrastrand anomalies in base
... become unscrambled and ligated in the orthodox order in conjunction with IES removal from polytene chromosomes. The polytene chromosomes are then fragmented, and ∼95% or more of the original micronuclear DNA sequence complexity is eliminated. These eliminated sequences are the spacers in micronuclea ...
... become unscrambled and ligated in the orthodox order in conjunction with IES removal from polytene chromosomes. The polytene chromosomes are then fragmented, and ∼95% or more of the original micronuclear DNA sequence complexity is eliminated. These eliminated sequences are the spacers in micronuclea ...
The antimicrobial resistance pattern of cultured human
... by differences in the core genomes of bacteria, archaea and eukarya. 2 Within archaea and bacteria, metabolic processes are different, and the cell walls of archaea are different from those of bacteria, thus explaining why some antibiotics effective against bacteria are not effective against archae ...
... by differences in the core genomes of bacteria, archaea and eukarya. 2 Within archaea and bacteria, metabolic processes are different, and the cell walls of archaea are different from those of bacteria, thus explaining why some antibiotics effective against bacteria are not effective against archae ...
Original Article:
... septicaemia. Bacteraemic infections often develop from the resident S. aureus flora located in the anterior nares of the patient. The understanding of the biological nature of S. aureus colonization is still limited, and most studies of the nasal carriage presume that individuals are colonized by a ...
... septicaemia. Bacteraemic infections often develop from the resident S. aureus flora located in the anterior nares of the patient. The understanding of the biological nature of S. aureus colonization is still limited, and most studies of the nasal carriage presume that individuals are colonized by a ...
slides - ARUP.utah.edu - The University of Utah
... May uncover copy number changes of unclear clinical significance Will not detect copy number changes in regions of the genome that are not on the array platform (chip) ...
... May uncover copy number changes of unclear clinical significance Will not detect copy number changes in regions of the genome that are not on the array platform (chip) ...
Navigating the HapMap - Oxford Academic
... likely to become a standard for assessing genetic diversity in human populations, against which additional communities are also likely to be characterized. Three years after the launch of the project, genotyping of 4.6 million SNPs is complete and a number of tools are now offering an integrated vie ...
... likely to become a standard for assessing genetic diversity in human populations, against which additional communities are also likely to be characterized. Three years after the launch of the project, genotyping of 4.6 million SNPs is complete and a number of tools are now offering an integrated vie ...
Prediction and Validation of Gene-Disease Associations
... diseases by looking for pairs of human diseases and model phenotypes that share a higher than expected number of orthologous genes. In this way, a number of new, and often surprising, model systems were found for human diseases. For instance, the human neural crest related developmental disorder Waa ...
... diseases by looking for pairs of human diseases and model phenotypes that share a higher than expected number of orthologous genes. In this way, a number of new, and often surprising, model systems were found for human diseases. For instance, the human neural crest related developmental disorder Waa ...
Tamarindus indica L. patterns of diversity from the genetic to the
... species recorded in tamarind niche plots was scored using binary approach; presence (1) and absence (0) in all the 187 plots inventoried. Each plot was grouped by its habitat type and country of collection. A table of regional species list and their respective frequencies among all plots per habitat ...
... species recorded in tamarind niche plots was scored using binary approach; presence (1) and absence (0) in all the 187 plots inventoried. Each plot was grouped by its habitat type and country of collection. A table of regional species list and their respective frequencies among all plots per habitat ...
ACEMBL System:
... protein assemblies play an important role in all these biological phenomena. In addition, other processes, e.g. entry of viruses into human cells, also critically hinge on multiple proteins or protein complexes5. Moreover, various prokaryotic microorganisms, with E.coli being the prototypical workho ...
... protein assemblies play an important role in all these biological phenomena. In addition, other processes, e.g. entry of viruses into human cells, also critically hinge on multiple proteins or protein complexes5. Moreover, various prokaryotic microorganisms, with E.coli being the prototypical workho ...
Nomenclature of Transposable Elements in Prokaryotes
... individual differences in base sequence and which might have undergone mutations or rearrangements in the laboratory (seeIV. E) . There is presently no advantage to giving each IS2 in a different location a specific as well as a generic name. Such a designation would provide no additional informatio ...
... individual differences in base sequence and which might have undergone mutations or rearrangements in the laboratory (seeIV. E) . There is presently no advantage to giving each IS2 in a different location a specific as well as a generic name. Such a designation would provide no additional informatio ...
Horizontal Gene Transfer between Bacteria
... (donor to recipient) between closely related or distantly related organisms; may be accompanied by expression of the introduced genetic material. ‘Transfer’ refers to translocation of genetic material into a cell, followed by stable integration into the recipient genome, including autonomously-repli ...
... (donor to recipient) between closely related or distantly related organisms; may be accompanied by expression of the introduced genetic material. ‘Transfer’ refers to translocation of genetic material into a cell, followed by stable integration into the recipient genome, including autonomously-repli ...
PROFILES OF TETRACYCLINE RESISTANT BACTERIA IN THE
... commensal bacteria associated with many retail foods. Subsequently, the question is whether these foodborne ART bacteria through daily food consumption are responsible for the prevalence of ART bacteria in human digestive ecosystems. To address this issue, the ART bacteria profiles in fecal samples ...
... commensal bacteria associated with many retail foods. Subsequently, the question is whether these foodborne ART bacteria through daily food consumption are responsible for the prevalence of ART bacteria in human digestive ecosystems. To address this issue, the ART bacteria profiles in fecal samples ...
Star Method for MSA and Its Parallelization
... One of the most promising architecture of processors to handle this complexity is Graphical Processing Unit (GPU). The GPU was designed formerly for graphics accelerator on personal computers and game consoles, but now has been developed to run general-purpose computing for many purposes, such as nu ...
... One of the most promising architecture of processors to handle this complexity is Graphical Processing Unit (GPU). The GPU was designed formerly for graphics accelerator on personal computers and game consoles, but now has been developed to run general-purpose computing for many purposes, such as nu ...
The complete inventory of the yeast Saccharomyces cerevisiae P
... genome sequencing and had not been previously characterized by specific mutant phenotypes. In this paper, these 16 yeast P-type ATPases have been clustered in 6 different families, using the phylogenetic relations determined by the PHYLIP program (Fig. 1). The prediction of the transmembrane topolog ...
... genome sequencing and had not been previously characterized by specific mutant phenotypes. In this paper, these 16 yeast P-type ATPases have been clustered in 6 different families, using the phylogenetic relations determined by the PHYLIP program (Fig. 1). The prediction of the transmembrane topolog ...
Unequal Crossing Over Locus by KIR Cutting Edge: Expansion of the
... The KIR genes map to 19q13.4 where they are arranged in a head to tail fashion spanning a region of roughly 150 Kb (12, 13). KIR genes are generally 80 –90% identical, whereas allelic variants of a single KIR gene tend to differ by 2% or less (14, 15). Except for a unique 14-kb sequence in the cente ...
... The KIR genes map to 19q13.4 where they are arranged in a head to tail fashion spanning a region of roughly 150 Kb (12, 13). KIR genes are generally 80 –90% identical, whereas allelic variants of a single KIR gene tend to differ by 2% or less (14, 15). Except for a unique 14-kb sequence in the cente ...
Genome-wide association studies for complex traits: consensus
... large in the design of case–control studies. The first is sample size, and with this issue the consensus view is clear: the more samples the better1,34,35,38. The initial wave of GWA studies has shown that, with rare exceptions, the effect sizes resulting from common SNP associations are modest, and ...
... large in the design of case–control studies. The first is sample size, and with this issue the consensus view is clear: the more samples the better1,34,35,38. The initial wave of GWA studies has shown that, with rare exceptions, the effect sizes resulting from common SNP associations are modest, and ...
Restriction Enzyme digestion of DNA
... endonucleases (RE), digest DNA by breaking bonds only within a specific short sequence of bases. These base sequences usually ran in size from 48 base pairs but can be as long as 23 base pairs. • Restriction endonucleases confer an adaptive advantage on bacteria by digesting foreign DNA usually from ...
... endonucleases (RE), digest DNA by breaking bonds only within a specific short sequence of bases. These base sequences usually ran in size from 48 base pairs but can be as long as 23 base pairs. • Restriction endonucleases confer an adaptive advantage on bacteria by digesting foreign DNA usually from ...
genome-tree-final - Gerstein Lab Publications
... (Swofford et al., 1996). Additional information (clickable trees, plots, etc.) is available from http://bioinfo.mbb.yale.edu/genome/trees. ...
... (Swofford et al., 1996). Additional information (clickable trees, plots, etc.) is available from http://bioinfo.mbb.yale.edu/genome/trees. ...
Ensembl Introduction
... • Joint project between EBI and Sanger • Funded primarily by the Wellcome Trust, additional funding by EMBL, NIH-NIAID, EU, BBSRC and MRC • Team of ca. 40 people, led by Ewan Birney (EBI) and Tim Hubbard (Sanger) ...
... • Joint project between EBI and Sanger • Funded primarily by the Wellcome Trust, additional funding by EMBL, NIH-NIAID, EU, BBSRC and MRC • Team of ca. 40 people, led by Ewan Birney (EBI) and Tim Hubbard (Sanger) ...
Applied and Environmental Microbiology
... and L. ivanovii (1, 18) are considered as pathogens. The pathogenicity is closely associated with a virulence gene cluster, although other genes like those coding for internalines are implicated in pathogenesis too (16). Like L. monocytogenes and L. ivanovii, L. seeligeri also carries a virulence ge ...
... and L. ivanovii (1, 18) are considered as pathogens. The pathogenicity is closely associated with a virulence gene cluster, although other genes like those coding for internalines are implicated in pathogenesis too (16). Like L. monocytogenes and L. ivanovii, L. seeligeri also carries a virulence ge ...
A novel DNA modification by sulphur
... Correlation of the Dnd phenotype with such DNA modification prompted us to look for other organisms that might have a similar modification system. A first attempt was made by analysing the DNA of selected microbes, plants and animals but only the DNA of Mycobacterium smegmatis and Streptomyces acrim ...
... Correlation of the Dnd phenotype with such DNA modification prompted us to look for other organisms that might have a similar modification system. A first attempt was made by analysing the DNA of selected microbes, plants and animals but only the DNA of Mycobacterium smegmatis and Streptomyces acrim ...
GENtle, a free multi-purpose molecular biology tool
... 2 Abstract A result of modern techniques in molecular biology, especially DNA sequencing, is the exponentially growing amount of available data. Besides giant, specialized databases, which are accessible over the Internet, all work groups in the field of molecular biology today need to handle, modif ...
... 2 Abstract A result of modern techniques in molecular biology, especially DNA sequencing, is the exponentially growing amount of available data. Besides giant, specialized databases, which are accessible over the Internet, all work groups in the field of molecular biology today need to handle, modif ...
Molecular diagnostics of infectious diseases
... original specimen; identification of organisms in pure cultures or from isolated colonies is usually easier than detection of organism in a direct specimen. DNA probes facilitate the identification of infectious agents that do not grow rapidly. Additionally, this technique allows for the diagnosis o ...
... original specimen; identification of organisms in pure cultures or from isolated colonies is usually easier than detection of organism in a direct specimen. DNA probes facilitate the identification of infectious agents that do not grow rapidly. Additionally, this technique allows for the diagnosis o ...
Control of Chromosome Pairing and Genome Evolution in Disomic
... maintained intact (with no further recombination) over selfing generations, so it is a “permanent” recombinant progeny. 96 monosomic progenies were recovered from this cross and the genetic map of this population serves as a control because recombination is essentially normal in the absence of Ph1. ...
... maintained intact (with no further recombination) over selfing generations, so it is a “permanent” recombinant progeny. 96 monosomic progenies were recovered from this cross and the genetic map of this population serves as a control because recombination is essentially normal in the absence of Ph1. ...
Metagenomics
Metagenomics is the study of genetic material recovered directly from environmental samples. The broad field may also be referred to as environmental genomics, ecogenomics or community genomics. While traditional microbiology and microbial genome sequencing and genomics rely upon cultivated clonal cultures, early environmental gene sequencing cloned specific genes (often the 16S rRNA gene) to produce a profile of diversity in a natural sample. Such work revealed that the vast majority of microbial biodiversity had been missed by cultivation-based methods. Recent studies use either ""shotgun"" or PCR directed sequencing to get largely unbiased samples of all genes from all the members of the sampled communities. Because of its ability to reveal the previously hidden diversity of microscopic life, metagenomics offers a powerful lens for viewing the microbial world that has the potential to revolutionize understanding of the entire living world. As the price of DNA sequencing continues to fall, metagenomics now allows microbial ecology to be investigated at a much greater scale and detail than before.