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Metzenberg, R.L. and J. Grotelueschen
Metzenberg, R.L. and J. Grotelueschen

... 1985. 82:2067-2071; Metzenberg and Grotelueschen, 1987. Fungal Genetics Newsl. 34:3944). The following data include the previous scorings of two crosses from the 1987 article and contains new data on the same two crosses from our own lab, and from others. As noted in the 1987 article, 38 segregants ...
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Big data mining yields novel insights on cancer
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... neighboring genes on a chromosome with consistently higher or lower coefficients in one PC (Fig. 1c). This approach is based on the finding that coordinated aberrations in expression for nearby genes suggest the presence of SCNAs8. The association of PCs with SCNAs was only observed in human samples ...
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Metagenomics



Metagenomics is the study of genetic material recovered directly from environmental samples. The broad field may also be referred to as environmental genomics, ecogenomics or community genomics. While traditional microbiology and microbial genome sequencing and genomics rely upon cultivated clonal cultures, early environmental gene sequencing cloned specific genes (often the 16S rRNA gene) to produce a profile of diversity in a natural sample. Such work revealed that the vast majority of microbial biodiversity had been missed by cultivation-based methods. Recent studies use either ""shotgun"" or PCR directed sequencing to get largely unbiased samples of all genes from all the members of the sampled communities. Because of its ability to reveal the previously hidden diversity of microscopic life, metagenomics offers a powerful lens for viewing the microbial world that has the potential to revolutionize understanding of the entire living world. As the price of DNA sequencing continues to fall, metagenomics now allows microbial ecology to be investigated at a much greater scale and detail than before.
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