• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
final exam in kje-2004
final exam in kje-2004

... Sequence homology: a conclusion about the common ancestry of sequences. The conclusion is based on the similarity between a pair of sequences. There is never a degree of homology. Sequence similarity: a quantitative measure between two sequences in an alignment. The similarity can be presented as fo ...
$doc.title

... transcription,  translation  and  DNA  replication.    The  approach  is  to  discuss  in  detail   the   players   involved   and   their   roles   in   each   of   the   processes.     The   major   mechanisms  by  which  bacteria  reg ...
Published Version  - Queen Mary University of London
Published Version - Queen Mary University of London

Genetic Engineering: How and why scientists manipulate DNA in
Genetic Engineering: How and why scientists manipulate DNA in

... homozygous dominant or heterozygous If unknown is homozygous dominant, all offspring will show dominant trait If unknown is heterozygous, some will show dominant trait, some show recessive trait Complete Problem Solving Lab 13.1 p.339 ...
An Investigation into the Genomic Evolution of the Histone Gene
An Investigation into the Genomic Evolution of the Histone Gene

... conversion - have been documented to occur, and are understood in molecular detail, but their role in concerted evolution is primarily based on theoretical and/or mathematical models with limited data from actual genome sequence to support them. It is the hypothesis of this research that if unequal ...
Phylogeny
Phylogeny

... Note: the COG functional annotation that we encountered early in the course approximately follows this same idea, only it considers more than two species. ...
Types of Chromosome Mutations
Types of Chromosome Mutations

... Inversion, deletion, duplication, and translocation can place a gene next to heterochromatin. Refer to Figure 12-23, Griffiths et al., 2015. ...
Alignment of mRNA to genomic DNA Sequence
Alignment of mRNA to genomic DNA Sequence

Unit 3 Problem Set Unit3_ProblemSet
Unit 3 Problem Set Unit3_ProblemSet

... 1. If a particular gene has a sequence that is 21% A (among A, C, G, and T), what percent can be deduced to be made up of G? 2. DNA has many properties that allowed us to isolate it in lab. For each property listed, describe how we exploited that property in the DNA isolation. a) VERY long b) Negati ...
Supplementary Materials and Methods
Supplementary Materials and Methods

... applied to the same dataset (not shown). Concerned that the whole genome duplication (WGD) may have affected our prediction of orthologs within the lineage including S. cerevisiae, S. castellii and C. glabrata,59 we filtered 9 groups of orthologous genes (from our alignment of 139) that are affected ...
What is a gene?
What is a gene?

... contributed one of the pair. Members of the pair could be identical (homozygous) or different (heterozygous). Mendel's factors were presumed to be particulate such that during gamete formation, each gamete received only one of the pair (segregation) and the segregation of different pairs of factors ...
BACTERIAL TRANSFORMATION Lab 15
BACTERIAL TRANSFORMATION Lab 15

... 3. Predict the results of a controlled transformation experiment using antibiotic resistance plasmids. 4. Demonstrate sterile technique for handling nonpathogenic as well as pathogenic microorganisms. ...
Slides - Barley World
Slides - Barley World

... wheat. Loss of parental genes and fragments was demonstrated in synthetic wheat allopolyploids, their relatives and their later generations.  The mechanism of gene-region loss in wheat appears to be intrastrand recombination between long terminal repeats of retrotransposable elements. ...
DNA Technology Notes
DNA Technology Notes

AG2010 lecture 1_basic genetics
AG2010 lecture 1_basic genetics

... Things to keep in mind before it’s too late • Homework accounts for half of the total grade and help you study for prelim (genetics prelim). • Often times drawings with concise explanations are really welcomed. • Grant/grant/grant…start early. • Homework due dates will be noticed on website. • Quest ...
DNA replication limits…
DNA replication limits…

... Incorrectly paired nucleotides that still remain following mismatch repair become permanent mutations after the next cell division. This is because once such mistakes are established, the cell no longer recognizes them as errors. Consider the case of wobble-induced replication errors. When these mis ...
HW3 - solutions
HW3 - solutions

... Cellular component – annotations of genes by the location of the protein they code to in the cell. For example – cell membrane. Biological process – annotations of genes by the pathway or process the proteins they code to take a role in. For example – biological adhesion. Molecular function – annota ...
Journal of Biotechnology
Journal of Biotechnology

... Gene per gene comparison in two genomes of B. amyloliquefaciens was performed using BLASTp algorithm implementation in the blastall.exe NCBI executable file (Madden, 2002). It was assumed that the genes in two B. amyloliquefaciens genomes showing the best alignment score and e-value below 0.0001 were ...
GENESIS: genome evolution scenarios
GENESIS: genome evolution scenarios

... the most common rearrangements are inversions (also called reversals in bioinformatics), where—from a mathematical point of view—a section of the genome is excised, reversed in orientation and re-inserted. Biologically, inversions can be caused by replication errors. But also large-scale duplication ...
File
File

... Goal 4: Learner will develop an understanding of the unity and diversity of life. 4.01 Analyze the classification of organisms according to their evolutionary relationships. (Historical development and changing nature of classification systems, similarities and differences between eukaryotic and pro ...
CILJANA MUTAGENEZA I GENETSKI MARKERI U SELEKCIJI SVINJA
CILJANA MUTAGENEZA I GENETSKI MARKERI U SELEKCIJI SVINJA

... the original unmutated template as well as the mutant strand. The mutants may also be counter-selected due to presence of mismatch repair system which favors the methylated template DNA. Many approaches have since now been developed to improve the efficiency of mutagenesis. A large number of SDM are ...
Molecular taxonomy,use of modern methods in the identification of a
Molecular taxonomy,use of modern methods in the identification of a

... agarose gel electrophoresis fails to efficiently resolve fragments that are more than 50,000 bases long, new methods have recently been developed that separate the very large fragments generated by enzymes that cut at rare sites. RFLP technique is regarded as the most sensitive method for strain ide ...
revision notes - Victoria University
revision notes - Victoria University

... The centromeres DO NOT separate at Metaphase 1 and double chromosomes (each with two chromatids) move towards each pole at Anaphase 1. In the second division cycle. All cells (gametes) are now haploid (half the usual chromosomal complement). As a result, many of the chromosomes present in the four h ...
Eliminate unnecessary lanes in gels
Eliminate unnecessary lanes in gels

... purposes of generating mutations. Given that in three months and as many different preparations of competent cells we only generated 3 transformants… Such a tragedy… ...
Class4_Synthetic_Genetics
Class4_Synthetic_Genetics

... -claimed that there are five times as many “negative” genetic interactions for essential genes when compared to non-essential genes -however, the cause of this may be due to the fact that the TET strains were very sick (and they were not quantitatively assessing the growth of the double mutant by co ...
< 1 ... 208 209 210 211 212 213 214 215 216 ... 445 >

Genome editing

Genome editing, or genome editing with engineered nucleases (GEEN) is a type of genetic engineering in which DNA is inserted, replaced, or removed from a genome using artificially engineered nucleases, or ""molecular scissors."" The nucleases create specific double-stranded break (DSBs) at desired locations in the genome, and harness the cell’s endogenous mechanisms to repair the induced break by natural processes of homologous recombination (HR) and nonhomologous end-joining (NHEJ). There are currently four families of engineered nucleases being used: Zinc finger nucleases (ZFNs), Transcription Activator-Like Effector Nucleases (TALENs), the CRISPR/Cas system, and engineered meganuclease re-engineered homing endonucleases.It is commonly practiced in genetic analysis that in order to understand the function of a gene or a protein function one interferes with it in a sequence-specific way and monitors its effects on the organism. However, in some organisms it is difficult or impossible to perform site-specific mutagenesis, and therefore more indirect methods have to be used, such as silencing the gene of interest by short RNA interference (siRNA) . Yet gene disruption by siRNA can be variable and incomplete. Genome editing with nucleases such as ZFN is different from siRNA in that the engineered nuclease is able to modify DNA-binding specificity and therefore can in principle cut any targeted position in the genome, and introduce modification of the endogenous sequences for genes that are impossible to specifically target by conventional RNAi. Furthermore, the specificity of ZFNs and TALENs are enhanced as two ZFNs are required in the recognition of their portion of the target and subsequently direct to the neighboring sequences.It was chosen by Nature Methods as the 2011 Method of the Year.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report