• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Pan-genomics: Unmasking the gene diversity hidden in the bacteria
Pan-genomics: Unmasking the gene diversity hidden in the bacteria

... within the same species is astonishing. As stated above, the sum of the shared and strain unique genes across all the compared genomes is called pan-genome, which in turn can be divided in core genome and accessory genome. In some cases, like the S. agalactiae, there is a predicted chance to get new ...
14–3 Human Molecular Genetics
14–3 Human Molecular Genetics

... Genetically engineered virus Slide 19 of 24 Copyright Pearson Prentice Hall ...
III. Mechanisms contributing to antibody diversity
III. Mechanisms contributing to antibody diversity

... of DNA along the chromosome b) Making proper exons from these segments requires rearranging and rejoining the segments to form immunoglobulin gene sequences C. L chain gene organization 1. Three genes code for each immunoglobulin L chain a) Two gene segments encode the variable domain of the human  ...
Reverse Genetics -
Reverse Genetics -

... - Yeast, mouse ES cells – standard practice possible because of high recombination rate B) Repair of induced double stand break (DSB) - HR repair of DSB from exogenous template to give KO or replacement. - Nonhomologous end joining (NHEJ) to give deletion (or insertion) 1) Transposable element excis ...
BLAST_and_Genome_Browser_tutorial
BLAST_and_Genome_Browser_tutorial

... Genome browser is a dynamic graphical display of several features identified from rice as well as from maize, sorghum, barley and wheat that were mapped on the rice genome. Some of these features are sequenced genetic markers, ESTs, cDNAs, CDSs, genes, insertion and repeat elements. The browser is a ...
Exam II
Exam II

... b. Using the features of this system, give an example of a genetic test that would show cis dominance. That is, describe a diploid strain for this region and describe the result that would show cis dominance. Be sure to explain what is meant by cis dominance. (You can add a reporter gene, as needed. ...
Bacterial Genomics
Bacterial Genomics

... Thermal tolerance?? GC basepairs (with 3 H-bonds) are stronger than are AT basepairs, so high GC genomes would seem to be less prone to denaturing at higher temperatures ...
Genotypic Frequency of Calpastatin Gene in Lori Sheep By PCR-RFLP Method
Genotypic Frequency of Calpastatin Gene in Lori Sheep By PCR-RFLP Method

... and in skeletal muscle. Calpastatin is expressed at a higher level of activity then the calpains themselves. Of the five domains, the N-terminal leader (L) domain does not appear to have any calpains inhibitory activity, but maybe involved in targeting or intracellular localization (Takano et al. 19 ...
Document
Document

... Mutations can arise as a consequence of misincorporation during replication ...
Slide 1
Slide 1

... – selectively bred stock, dogs, and other animals. ...
Mutations Worksheet
Mutations Worksheet

... If a substitution changes the amino acid, it’s called a MISSENSE point mutation. If a substitution does not change the amino acid, it’s called a SILENT point mutation. If a substitution changes the amino acid to a “stop,” it’s called a NONSENSE point mutation. Complete the boxes below. Classify each ...
PPT
PPT

... • Mechanistically predicting relationships between different data types is very difficult • Empirical mappings are important • Functions from Genome to Phenotype stands out in importance G is the most abundant data form - heritable and precise. F is of greatest interest. DNA ...
pGLO Lab
pGLO Lab

... 2. Describe how you could use two LB/agar plates, some E. coli and some ampicillin to determine how E. coli cells are affected by ampicillin. 3. What would you expect your experimental results to indicate about the effect ampicillin has on E. coli? Genetic transformation involves the insertion of so ...
DNA cloning
DNA cloning

... Producing Clones of Cells Carrying Recombinant Plasmids • Several steps are required to clone the hummingbird β-globin gene in a bacterial plasmid – The hummingbird genomic DNA and a bacterial plasmid are isolated – Both are cut with the same restriction enzyme – The fragments are mixed, and DNA li ...
Document
Document

... leukemia, cancers, and many other genetically-related conditions. • The map also revealed several hundred previously unknown genes. • With the signal (exon) to noise (intron) ratio being so low (meaning more noise to hide the signal) in the human genome, it will be challenging to completely identify ...
Laboratory 2: How do you begin to clone a gene?
Laboratory 2: How do you begin to clone a gene?

... red fluorescent protein gene in bacteria Educational (students will be able to): • Identify the common characteristics of plasmids • Explain how plasmids are used as vectors in gene cloning/expression • Describe the function of restriction enzymes • Explain restriction enzymes are used to create rec ...
emboj7601722-sup
emboj7601722-sup

... isolated by screening λ Fix II 129/SvJ mouse genomic DNA library with probes which correspond to 3’ and 5’ UTR of mouse UbC cDNA and restriction mapped. We designed knockout construct by replacing 2.2 kb UbC coding region with a 1.4 kb fragment containing enhanced green fluorescent protein (GFP) and ...
Untitled
Untitled

... architect’s plan. The double helix has become a cultural icon, not to mention lazy advertising shorthand for ‘Ooh, science!’ But while the language of genetics has infiltrated the public consciousness, a genuine understanding of what our genes are and what they do has not. Most biology textbooks de ...
Practise Midterm Exam
Practise Midterm Exam

... In the genomic DNA sequence shown above, draw boxes around the exons. ...
Analysis of ATP Synthase Genes within Elizabethkingia anophelis R26
Analysis of ATP Synthase Genes within Elizabethkingia anophelis R26

... Elizabethkingia anophelis, a gram negative bacteria, is responsible for causing human disease in dozens of people across the US per year and is quite resistive to many antibiotics. By looking at similar, specific genes within the bacteria, we aim to better understand Elizabethkingia anophelis R26. F ...
Population Genetics and a Study of Speciation Using Next
Population Genetics and a Study of Speciation Using Next

... levels (i.e., transcribed more times into RNA molecules) than others, and these differences in RNA abundance are reflected in the population of cDNA. If the researchers had directly sequenced this cDNA, they would have recovered sequences from highly expressed genes many times before observing sequen ...
gene therapy - muhammad1988adeel
gene therapy - muhammad1988adeel

ppt_I
ppt_I

... • 22,287 'gene loci‘ defined, consisting of 19,599 protein-coding genes in the human genome and 2,188 DNA additional segments ‘predicted’ to be protein-coding genes – 1183 genes ‘were born’ in the last 60-100 My – ~ 30 genes ‘died’ in a similar time period ...
genetically
genetically

... • Recently was considered that the enzyme is coded by the gene with two alleles (non-functional is recessive) • Molecular analysis shown more than 50 alleles in the locus • Most alleles has not phenotypic effect • 8 alleles in homozygotic conditions have enzyme activity 1 – 50% from the norm. ...
Genetics Final Review - Valhalla High School
Genetics Final Review - Valhalla High School

... homes may vary in height, weight, and intelligence. The most probable explanation for these differences is that 1. original genes of each twin increased in number as they developed ...
< 1 ... 212 213 214 215 216 217 218 219 220 ... 445 >

Genome editing

Genome editing, or genome editing with engineered nucleases (GEEN) is a type of genetic engineering in which DNA is inserted, replaced, or removed from a genome using artificially engineered nucleases, or ""molecular scissors."" The nucleases create specific double-stranded break (DSBs) at desired locations in the genome, and harness the cell’s endogenous mechanisms to repair the induced break by natural processes of homologous recombination (HR) and nonhomologous end-joining (NHEJ). There are currently four families of engineered nucleases being used: Zinc finger nucleases (ZFNs), Transcription Activator-Like Effector Nucleases (TALENs), the CRISPR/Cas system, and engineered meganuclease re-engineered homing endonucleases.It is commonly practiced in genetic analysis that in order to understand the function of a gene or a protein function one interferes with it in a sequence-specific way and monitors its effects on the organism. However, in some organisms it is difficult or impossible to perform site-specific mutagenesis, and therefore more indirect methods have to be used, such as silencing the gene of interest by short RNA interference (siRNA) . Yet gene disruption by siRNA can be variable and incomplete. Genome editing with nucleases such as ZFN is different from siRNA in that the engineered nuclease is able to modify DNA-binding specificity and therefore can in principle cut any targeted position in the genome, and introduce modification of the endogenous sequences for genes that are impossible to specifically target by conventional RNAi. Furthermore, the specificity of ZFNs and TALENs are enhanced as two ZFNs are required in the recognition of their portion of the target and subsequently direct to the neighboring sequences.It was chosen by Nature Methods as the 2011 Method of the Year.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report