Figure 15 - GEP Community Server
... header) is selected and the diagram will only show the motif instances that were used to construct each motif. Because we have previously specified in our search parameters that we expect to find zero or one instance of each motif within each sequence, each sequence in the block diagram will contain ...
... header) is selected and the diagram will only show the motif instances that were used to construct each motif. Because we have previously specified in our search parameters that we expect to find zero or one instance of each motif within each sequence, each sequence in the block diagram will contain ...
High-Resolution Single-Copy Gene Fluorescence in Situ
... In a previous study, we found that three-dimensional (3-D) FISH, which is known to preserve the nuclear architecture and chromatin morphology, is not suitable for single-copy gene mapping on maize pachytene chromosomes. Chen et al. (2000) demonstrated that a mild squash procedure produced high-quali ...
... In a previous study, we found that three-dimensional (3-D) FISH, which is known to preserve the nuclear architecture and chromatin morphology, is not suitable for single-copy gene mapping on maize pachytene chromosomes. Chen et al. (2000) demonstrated that a mild squash procedure produced high-quali ...
Article The Pseudoautosomal Regions of the U/V Sex
... expansion of the SDR, and an extensive PAR may be preserved. This may be expected to occur, for example, in organisms with a low level of phenotypic sexual dimorphism (e.g., Ahmed et al. 2014) or where SA selection has been resolved by alternative processes such as the evolution of sex-biased gene e ...
... expansion of the SDR, and an extensive PAR may be preserved. This may be expected to occur, for example, in organisms with a low level of phenotypic sexual dimorphism (e.g., Ahmed et al. 2014) or where SA selection has been resolved by alternative processes such as the evolution of sex-biased gene e ...
E.coli
... sequence and can fish for it Other times we know the amino acid sequence and can work backward, but with degeneracy (64 codons, 20 aa’s) Typically use at least 17mers to guarantee that the don’t get random association Probes derived from a different species are heterologous With big eukaryotic genes ...
... sequence and can fish for it Other times we know the amino acid sequence and can work backward, but with degeneracy (64 codons, 20 aa’s) Typically use at least 17mers to guarantee that the don’t get random association Probes derived from a different species are heterologous With big eukaryotic genes ...
Identification and Analysis of Arabidopsis Expressed Sequence
... Sequencing of the Arabidopsis genome has led to the identification of thousands of new putative genes based on the predicted proteins they encode. Genes encoding tRNAs, ribosomal RNAs, and small nucleolar RNAs have also been annotated; however, a potentially important class of genes has largely esca ...
... Sequencing of the Arabidopsis genome has led to the identification of thousands of new putative genes based on the predicted proteins they encode. Genes encoding tRNAs, ribosomal RNAs, and small nucleolar RNAs have also been annotated; however, a potentially important class of genes has largely esca ...
Multiple Mechanisms Contribute to Lateral Transfer of an
... (20 mg/ml), and kanamycin (30 mg/ml) supplemented the culture medium. The LB sucrose plates were prepared by adding 5% sucrose to LB agar plates. Acinetobacter sp. DS002 strains were grown in M9 medium containing filter-sterilized benzoate (5 mM) as a carbon source. Exconjugants of Acinetobacter sp. ...
... (20 mg/ml), and kanamycin (30 mg/ml) supplemented the culture medium. The LB sucrose plates were prepared by adding 5% sucrose to LB agar plates. Acinetobacter sp. DS002 strains were grown in M9 medium containing filter-sterilized benzoate (5 mM) as a carbon source. Exconjugants of Acinetobacter sp. ...
Chapter 15
... • Offspring with a phenotype matching one of the parental phenotypes are called parental types • Offspring with nonparental phenotypes (new combinations of traits) are called recombinant types, or recombinants • A 50% frequency of recombination is observed ...
... • Offspring with a phenotype matching one of the parental phenotypes are called parental types • Offspring with nonparental phenotypes (new combinations of traits) are called recombinant types, or recombinants • A 50% frequency of recombination is observed ...
Diploidization of meiosis in autotetraploids
... in progress even though the polyploidization event probably occurred about thirty million years ago [22]. Furthermore, even within a single species, there can be differences in diploidization rate between lines that have existed at the tetraploid level for the same amount of time [14,20]••. This pro ...
... in progress even though the polyploidization event probably occurred about thirty million years ago [22]. Furthermore, even within a single species, there can be differences in diploidization rate between lines that have existed at the tetraploid level for the same amount of time [14,20]••. This pro ...
LESSON 4 Understanding Genetic Tests to Detect BRCA1
... 19. Tell students that one of the tools in the bioinformatics toolkit they will be using is called BLAST – Basic Local Alignment Search Tool. BLAST can be used to compare the sequences of two or more proteins or nucleic acid molecules, or to compare a single sequence to a collection of sequences in ...
... 19. Tell students that one of the tools in the bioinformatics toolkit they will be using is called BLAST – Basic Local Alignment Search Tool. BLAST can be used to compare the sequences of two or more proteins or nucleic acid molecules, or to compare a single sequence to a collection of sequences in ...
Part 3 - Bioinformatics.ca
... How does Segway work? • Goal is to segment the genome into sub-classes. In each case, the tools identify certain data properties that subsets of the genome. Based on the groupings, the presence of known features (e.g. transcription start regions) is scored to suggest the functional meaning of the c ...
... How does Segway work? • Goal is to segment the genome into sub-classes. In each case, the tools identify certain data properties that subsets of the genome. Based on the groupings, the presence of known features (e.g. transcription start regions) is scored to suggest the functional meaning of the c ...
投影片 1 - cmcmurillo
... the brother/sister of the nucleus donor. The identity of the clone is unclear. ...
... the brother/sister of the nucleus donor. The identity of the clone is unclear. ...
File
... Normal female cells contain 46 chromosomes, 23 received from the mother via the egg and 23 from the father via the sperm. The 46 chromosomes consist of 22 homologous pairs of autosomes (chromosomes that do not determine the sex of the organism ) and 2 Xchromosomes that are sex-determining . Normal m ...
... Normal female cells contain 46 chromosomes, 23 received from the mother via the egg and 23 from the father via the sperm. The 46 chromosomes consist of 22 homologous pairs of autosomes (chromosomes that do not determine the sex of the organism ) and 2 Xchromosomes that are sex-determining . Normal m ...
An Approximate Approach to DNA Denaturation
... helix involved in this bond disruption are low frequency collective motion of the entire macromolecule. A detailed theory or description of melting of such a system is quite different from t h a t of a small molecule with a much simpler dynamics. The major motion involving the H-bonds is the so-call ...
... helix involved in this bond disruption are low frequency collective motion of the entire macromolecule. A detailed theory or description of melting of such a system is quite different from t h a t of a small molecule with a much simpler dynamics. The major motion involving the H-bonds is the so-call ...
The viriosphere, diversity, and genetic exchange within phage
... and siphoviruses also occurred. However, given the vast diversity of phages in seawater, and that only a tiny fraction of potential hosts have been cultured, cultureindependent methods have been used to estimate the genetic variation in natural virus communities. In particular, advances in technique ...
... and siphoviruses also occurred. However, given the vast diversity of phages in seawater, and that only a tiny fraction of potential hosts have been cultured, cultureindependent methods have been used to estimate the genetic variation in natural virus communities. In particular, advances in technique ...
Multifactorial Traits
... alcoholism has the same problem. Are these characteristics—writing talent, obesity, and alcoholism—inherited or learned? Or are they a combination of nature (genetics) and nurture (the environment)? Most of the traits and medical conditions mentioned so far in this book are singlegene characteristic ...
... alcoholism has the same problem. Are these characteristics—writing talent, obesity, and alcoholism—inherited or learned? Or are they a combination of nature (genetics) and nurture (the environment)? Most of the traits and medical conditions mentioned so far in this book are singlegene characteristic ...
Demarcation of coding and non-coding regions of DNA using linear
... my eccentric ideas and has made the different ramifications of Signal Processing so easy to me by the depth of knowledge he possesses of them. His intuition and keen discernment have always kindled my mind to enlightenment. His memorable advice, given on 21 January, 2005 at 3:15 PM, "On the road of ...
... my eccentric ideas and has made the different ramifications of Signal Processing so easy to me by the depth of knowledge he possesses of them. His intuition and keen discernment have always kindled my mind to enlightenment. His memorable advice, given on 21 January, 2005 at 3:15 PM, "On the road of ...
PraderWilli syndrome resulting from an unbalanced translocation
... While no clear genotype–phenotype correlations have been demonstrated in PWS caused by unbalanced translocations, two recent reports illustrate the tendency toward expanded phenotypes in these cases (21, 22). To our knowledge, only one instance of an unbalanced translocation (5;15) has been reported ...
... While no clear genotype–phenotype correlations have been demonstrated in PWS caused by unbalanced translocations, two recent reports illustrate the tendency toward expanded phenotypes in these cases (21, 22). To our knowledge, only one instance of an unbalanced translocation (5;15) has been reported ...
Genetics and Genomics
... 2. Y-linked (holandric) Inheritance ......................................................................................... 3. Sex influenced inheritance .................................................................................................. 4. Sex limited inheritance .................. ...
... 2. Y-linked (holandric) Inheritance ......................................................................................... 3. Sex influenced inheritance .................................................................................................. 4. Sex limited inheritance .................. ...
Lecture PPT - Carol Lee Lab
... among which the rapidly evolving KRAB-zinc finger genes are markedly over-represented. KRAB-zinc fingers have on average accumulated more amino acid differences between humans and chimpanzees than other genes, indicating that they may have contributed disproportionately to the phenotypic differences ...
... among which the rapidly evolving KRAB-zinc finger genes are markedly over-represented. KRAB-zinc fingers have on average accumulated more amino acid differences between humans and chimpanzees than other genes, indicating that they may have contributed disproportionately to the phenotypic differences ...
PDF - Molecular Cytogenetics
... that can arise following mitotic errors in normal cells. In addition there are also cases where a new lineage emerged from multiple trisomic or monosomic rescue events in altered cells [14–17]. The possibility of independent rescue events occurring in a single individual lineage is supported by the ...
... that can arise following mitotic errors in normal cells. In addition there are also cases where a new lineage emerged from multiple trisomic or monosomic rescue events in altered cells [14–17]. The possibility of independent rescue events occurring in a single individual lineage is supported by the ...
The biased nucleotide composition of the HIV genome: a constant
... and the untranslated 5’ leader RNA are less A-rich than the pol gene (Table 2). The stability of the base composition over time also holds when examining smaller genome fragments, e.g. from the gag or pol genes, and is even true for highly variable genes such as env. The intriguing question is then: ...
... and the untranslated 5’ leader RNA are less A-rich than the pol gene (Table 2). The stability of the base composition over time also holds when examining smaller genome fragments, e.g. from the gag or pol genes, and is even true for highly variable genes such as env. The intriguing question is then: ...
Slide - Gerstein Lab
... information associated with these molecules, on a large-scale. • Bioinformatics is a practical discipline with many applications. ...
... information associated with these molecules, on a large-scale. • Bioinformatics is a practical discipline with many applications. ...
Open access article
... We have established tools for forward and reverse genetic analysis of the legume Lotus (Lotus japonicus). A structured population of M2 progeny of 4,904 ethyl methanesulfonate-mutagenized M1 embryos is available for single nucleotide polymorphism mutation detection, using a TILLING (for Targeting In ...
... We have established tools for forward and reverse genetic analysis of the legume Lotus (Lotus japonicus). A structured population of M2 progeny of 4,904 ethyl methanesulfonate-mutagenized M1 embryos is available for single nucleotide polymorphism mutation detection, using a TILLING (for Targeting In ...
Production of Recombinant Molecules
... vector that contained these segments of DNA: 1. 2 regions homologous to the sheep COL1A1 gene. This gene encodes Type 1 collagen. (Its absence in humans causes the inherited disease osteogenesis imperfecta.) This locus was chosen because fibroblasts secrete large amounts of collagen and thus one wou ...
... vector that contained these segments of DNA: 1. 2 regions homologous to the sheep COL1A1 gene. This gene encodes Type 1 collagen. (Its absence in humans causes the inherited disease osteogenesis imperfecta.) This locus was chosen because fibroblasts secrete large amounts of collagen and thus one wou ...
Human genome
The human genome is the complete set of nucleic acid sequence for humans (Homo sapiens), encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. Human genomes include both protein-coding DNA genes and noncoding DNA. Haploid human genomes, which are contained in germ cells (the egg and sperm gamete cells created in the meiosis phase of sexual reproduction before fertilization creates a zygote) consist of three billion DNA base pairs, while diploid genomes (found in somatic cells) have twice the DNA content. While there are significant differences among the genomes of human individuals (on the order of 0.1%), these are considerably smaller than the differences between humans and their closest living relatives, the chimpanzees (approximately 4%) and bonobos. Humans share 50% of their DNA with bananas.The Human Genome Project produced the first complete sequences of individual human genomes, with the first draft sequence and initial analysis being published on February 12, 2001. The human genome was the first of all vertebrates to be completely sequenced. As of 2012, thousands of human genomes have been completely sequenced, and many more have been mapped at lower levels of resolution. The resulting data are used worldwide in biomedical science, anthropology, forensics and other branches of science. There is a widely held expectation that genomic studies will lead to advances in the diagnosis and treatment of diseases, and to new insights in many fields of biology, including human evolution.Although the sequence of the human genome has been (almost) completely determined by DNA sequencing, it is not yet fully understood. Most (though probably not all) genes have been identified by a combination of high throughput experimental and bioinformatics approaches, yet much work still needs to be done to further elucidate the biological functions of their protein and RNA products. Recent results suggest that most of the vast quantities of noncoding DNA within the genome have associated biochemical activities, including regulation of gene expression, organization of chromosome architecture, and signals controlling epigenetic inheritance.There are an estimated 20,000-25,000 human protein-coding genes. The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further. Protein-coding sequences account for only a very small fraction of the genome (approximately 1.5%), and the rest is associated with non-coding RNA molecules, regulatory DNA sequences, LINEs, SINEs, introns, and sequences for which as yet no function has been elucidated.