Molecualr Biology and Evolution
... Parsimony and some distance analyses of the nifK amino acid sequences provide support for vertical descent of nzyK, but other distance trees provide support for the lateral transfer of the gene. Bootstrap support was found for both hypotheses in all trees; the nifK data do not definitively favor one ...
... Parsimony and some distance analyses of the nifK amino acid sequences provide support for vertical descent of nzyK, but other distance trees provide support for the lateral transfer of the gene. Bootstrap support was found for both hypotheses in all trees; the nifK data do not definitively favor one ...
Gene as the unit of genetic material - E
... of larger cell size than cell number. This increased size does offer some commercial advantages. Important triploid plants include, some potatoes, bananas, watermelons and Winesap apples. All of these crops must be propagated asexually. Examples of tetraploids are alfalfa, coffee, peanuts and McInt ...
... of larger cell size than cell number. This increased size does offer some commercial advantages. Important triploid plants include, some potatoes, bananas, watermelons and Winesap apples. All of these crops must be propagated asexually. Examples of tetraploids are alfalfa, coffee, peanuts and McInt ...
Divergent evolution of oxidosqualene cyclases in plants
... OSC genes (Inagaki et al., 2011). One of these (Os02g04710 ⁄ OsOSC2) encodes cycloartenol synthase (CS), while a further two (Os11g08569 ⁄ OsOSC7 and Os11g18194 ⁄ OsOSC8) have been shown to synthesize the triterpenes, parkeol and achilleol B, respectively, in Saccharomyces cerevisiae GIL77 (Ito et a ...
... OSC genes (Inagaki et al., 2011). One of these (Os02g04710 ⁄ OsOSC2) encodes cycloartenol synthase (CS), while a further two (Os11g08569 ⁄ OsOSC7 and Os11g18194 ⁄ OsOSC8) have been shown to synthesize the triterpenes, parkeol and achilleol B, respectively, in Saccharomyces cerevisiae GIL77 (Ito et a ...
D. melanogaster - GEP Community Server
... Retrieve the sequences of the initial exons from the Transcript Details tab of the Gene Record Finder Use placement of the flanking exons to reduce the size of the search region if possible Increase sensitivity of nucleotide searches Change Program Selection to blastn Change Word size to 7 Change Ma ...
... Retrieve the sequences of the initial exons from the Transcript Details tab of the Gene Record Finder Use placement of the flanking exons to reduce the size of the search region if possible Increase sensitivity of nucleotide searches Change Program Selection to blastn Change Word size to 7 Change Ma ...
A process for analysis of microarray comparative genomics
... and low log-ratios [6-9]. These software methods can be broadly categorised into smoothing or segmentation algorithms. The smoothing algorithms use information from a number of genes locally to assign the log2(Cy3/Cy5), whereas the segmentation algorithms define the set of genes. It has been shown w ...
... and low log-ratios [6-9]. These software methods can be broadly categorised into smoothing or segmentation algorithms. The smoothing algorithms use information from a number of genes locally to assign the log2(Cy3/Cy5), whereas the segmentation algorithms define the set of genes. It has been shown w ...
Printable version - Chromosome 18 Registry and Research Society
... each chromosome has a waistband constriction somewhere along its length. This is called a centromere and it makes the chromosomes look as if they have a long and a short arm. The convention is that the chromosome is always oriented with the short arm on top. You will also see that this particular ka ...
... each chromosome has a waistband constriction somewhere along its length. This is called a centromere and it makes the chromosomes look as if they have a long and a short arm. The convention is that the chromosome is always oriented with the short arm on top. You will also see that this particular ka ...
Divergent evolution of oxidosqualene cyclases in plants
... OSC genes (Inagaki et al., 2011). One of these (Os02g04710 ⁄ OsOSC2) encodes cycloartenol synthase (CS), while a further two (Os11g08569 ⁄ OsOSC7 and Os11g18194 ⁄ OsOSC8) have been shown to synthesize the triterpenes, parkeol and achilleol B, respectively, in Saccharomyces cerevisiae GIL77 (Ito et a ...
... OSC genes (Inagaki et al., 2011). One of these (Os02g04710 ⁄ OsOSC2) encodes cycloartenol synthase (CS), while a further two (Os11g08569 ⁄ OsOSC7 and Os11g18194 ⁄ OsOSC8) have been shown to synthesize the triterpenes, parkeol and achilleol B, respectively, in Saccharomyces cerevisiae GIL77 (Ito et a ...
A molecular method for assessing meiofauna diversity in marine
... 1991). The 18S rRNA gene is used to determine interphylum relationships among metazoans (Field et al. 1988), but can also be used to infer intraphylum phylogenetic relationships (Blaxter, et al. 1998). As a ribosomal RNA gene, 18S rDNA contains variable regions as well as highly conserved regions (H ...
... 1991). The 18S rRNA gene is used to determine interphylum relationships among metazoans (Field et al. 1988), but can also be used to infer intraphylum phylogenetic relationships (Blaxter, et al. 1998). As a ribosomal RNA gene, 18S rDNA contains variable regions as well as highly conserved regions (H ...
Slide 1
... human leukocyte antigen (HLA) loci on the short arm of chromosome 6. Age at onset, clinical features, and course of the disease are described. Although the mean age of onset was 34 years in this family, in 6 of 41 affected individuals onset was below 15 years of age and was accompanied by the unique ...
... human leukocyte antigen (HLA) loci on the short arm of chromosome 6. Age at onset, clinical features, and course of the disease are described. Although the mean age of onset was 34 years in this family, in 6 of 41 affected individuals onset was below 15 years of age and was accompanied by the unique ...
Plant centromeres: structure and control Eric J Richards and R Kelly
... few plant centromere regions which have been at least partially physically mapped. The size of the regions encompassing the centromere-associated repeats is large. For example, the maize B centromere region is estimated to be at least 9 Mbp in size [31•]. Even Arabidopsis, with its relatively small ...
... few plant centromere regions which have been at least partially physically mapped. The size of the regions encompassing the centromere-associated repeats is large. For example, the maize B centromere region is estimated to be at least 9 Mbp in size [31•]. Even Arabidopsis, with its relatively small ...
Nucleotide sequence and genome organization of foot-and
... 94 % of the FMDV genome indicating that the size of the FMDV genome is about 8500 nucleotides, i.e. 500 nucleotides longer than estimated from sizinggets by (17). This size correction is also supported by the sizing and the partial sequence analysis of cDNA copies that cover the as yet uncloned 5'-t ...
... 94 % of the FMDV genome indicating that the size of the FMDV genome is about 8500 nucleotides, i.e. 500 nucleotides longer than estimated from sizinggets by (17). This size correction is also supported by the sizing and the partial sequence analysis of cDNA copies that cover the as yet uncloned 5'-t ...
Snímek 1
... (5) meiotic elimination in some species is counter-balanced by processes of drive at mitosis, mainly in the gametophytes, and less frequently at meiosis (equilibrium frequencies in populations) (6) neutral effects; negative and quantitative effects on the phenotype when present in high numbers (redu ...
... (5) meiotic elimination in some species is counter-balanced by processes of drive at mitosis, mainly in the gametophytes, and less frequently at meiosis (equilibrium frequencies in populations) (6) neutral effects; negative and quantitative effects on the phenotype when present in high numbers (redu ...
Detecting a Transposon in Corn
... independently, but Ds depends on Ac for transposition. She showed that transposons may inactivate gene expression by inserting into a gene, or may reactivate expression by jumping out. Thus, McClintock explained color variegations, such as speckled kernels, that had intrigued botanists for centuries ...
... independently, but Ds depends on Ac for transposition. She showed that transposons may inactivate gene expression by inserting into a gene, or may reactivate expression by jumping out. Thus, McClintock explained color variegations, such as speckled kernels, that had intrigued botanists for centuries ...
Site specific insertion of a type I rDNA dement into a unique
... resulting Hindlll fragments, 8a/5 and 8a/6 are shown on the physical map. The 12.5Kb EcoRI fragment has been re-cloned into pBR322 and Figure 2 shows digests of this recombinant plasmid, pMB8a, with a number of restriction endonucleases. The right hand panel of Figure 2 shows a Southern hybridisatio ...
... resulting Hindlll fragments, 8a/5 and 8a/6 are shown on the physical map. The 12.5Kb EcoRI fragment has been re-cloned into pBR322 and Figure 2 shows digests of this recombinant plasmid, pMB8a, with a number of restriction endonucleases. The right hand panel of Figure 2 shows a Southern hybridisatio ...
the x chromosome in population genetics
... in which it is being studied (BOX 1; TABLE 1). In this context, what does the mammalian X chromosome look like? In many respects, it looks very similar to an autosome, which is not surprising given its history. The two sex chromosomes, the X and the Y, diverged from a single autosome ~300 million ye ...
... in which it is being studied (BOX 1; TABLE 1). In this context, what does the mammalian X chromosome look like? In many respects, it looks very similar to an autosome, which is not surprising given its history. The two sex chromosomes, the X and the Y, diverged from a single autosome ~300 million ye ...
Transgenic Plastids in Basic Research and Plant Biotechnology
... to effective inhibition of plastid protein biosynthesis by spectinomycin (an aminoglycoside antibiotic speci®cally blocking translation on prokaryotic-type 70 S ribosomes). A successfully transformed chloroplast expresses the spectinomycin-resistance gene, aadA, thus allowing for continued cell and ...
... to effective inhibition of plastid protein biosynthesis by spectinomycin (an aminoglycoside antibiotic speci®cally blocking translation on prokaryotic-type 70 S ribosomes). A successfully transformed chloroplast expresses the spectinomycin-resistance gene, aadA, thus allowing for continued cell and ...
Consistent risk group-associated differences in human
... differences between sequences of the genes were moderately correlated (around 0.30). Surprisingly, when only silent changes were counted, the correlations dropped almost to zero, indicating that the evolution towards independence was more advanced in the silent than in the non-silent positions. This ...
... differences between sequences of the genes were moderately correlated (around 0.30). Surprisingly, when only silent changes were counted, the correlations dropped almost to zero, indicating that the evolution towards independence was more advanced in the silent than in the non-silent positions. This ...
Full Text PDF - Mary Ann Liebert, Inc. publishers
... These expression domains are believed to remain insulated from neighboring sequences and are thought to include all regulatory elements that are necessary for their correct gene expression (Fig. 1). They are frequently represented as chromatin fibers in the form of loops whose ends remain attached t ...
... These expression domains are believed to remain insulated from neighboring sequences and are thought to include all regulatory elements that are necessary for their correct gene expression (Fig. 1). They are frequently represented as chromatin fibers in the form of loops whose ends remain attached t ...
array CGH - Unique The Rare Chromosome Disorder Support Group
... missing or duplicated. At present we only understand the role of a small minority of genes and their association with particular clinical features. However, where a gene’s association with a particular clinical feature is known, it can be informative for the care and monitoring of your child’s healt ...
... missing or duplicated. At present we only understand the role of a small minority of genes and their association with particular clinical features. However, where a gene’s association with a particular clinical feature is known, it can be informative for the care and monitoring of your child’s healt ...
Evolution of antifreeze glycoprotein gene from a trypsinogen gene in
... sizes besides the eight originally described have been subsequently identified (12, 13). Collectively they are maintained at very high circulatory levels of 30–35 mgyml (6, 10). Notothenioid AFGPs are encoded by large gene families in which each member gene encodes a large polyprotein precursor cont ...
... sizes besides the eight originally described have been subsequently identified (12, 13). Collectively they are maintained at very high circulatory levels of 30–35 mgyml (6, 10). Notothenioid AFGPs are encoded by large gene families in which each member gene encodes a large polyprotein precursor cont ...
An In Silico Investigation Into the Discovery of Novel Cis
... Several potential cis-regulatory motifs were identified in this investigation and one in particular that was common to both PAX7 and PAX3 and also to NF1, could have implications for the role of PAX7 in Alveolar Rhabdomyosarcoma and may be the cornerstone to more exciting, unique scientific investig ...
... Several potential cis-regulatory motifs were identified in this investigation and one in particular that was common to both PAX7 and PAX3 and also to NF1, could have implications for the role of PAX7 in Alveolar Rhabdomyosarcoma and may be the cornerstone to more exciting, unique scientific investig ...
Handout - 6 - CM - Outline Genomic Model for HL7 V2
... This panel code does not carry values in its OBX-5 It defines the structure within the LOINC data base. It will not be included in the message since we are planning to use OBX-4 content to define the hierarchy rather than by nested OBRs The code for the CWE is the ID specified for the variant in the ...
... This panel code does not carry values in its OBX-5 It defines the structure within the LOINC data base. It will not be included in the message since we are planning to use OBX-4 content to define the hierarchy rather than by nested OBRs The code for the CWE is the ID specified for the variant in the ...
Getting Started
... humans and computers. necessary for high-throughput “omics” datasets allows data sharing across databases ...
... humans and computers. necessary for high-throughput “omics” datasets allows data sharing across databases ...
Human genome
The human genome is the complete set of nucleic acid sequence for humans (Homo sapiens), encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. Human genomes include both protein-coding DNA genes and noncoding DNA. Haploid human genomes, which are contained in germ cells (the egg and sperm gamete cells created in the meiosis phase of sexual reproduction before fertilization creates a zygote) consist of three billion DNA base pairs, while diploid genomes (found in somatic cells) have twice the DNA content. While there are significant differences among the genomes of human individuals (on the order of 0.1%), these are considerably smaller than the differences between humans and their closest living relatives, the chimpanzees (approximately 4%) and bonobos. Humans share 50% of their DNA with bananas.The Human Genome Project produced the first complete sequences of individual human genomes, with the first draft sequence and initial analysis being published on February 12, 2001. The human genome was the first of all vertebrates to be completely sequenced. As of 2012, thousands of human genomes have been completely sequenced, and many more have been mapped at lower levels of resolution. The resulting data are used worldwide in biomedical science, anthropology, forensics and other branches of science. There is a widely held expectation that genomic studies will lead to advances in the diagnosis and treatment of diseases, and to new insights in many fields of biology, including human evolution.Although the sequence of the human genome has been (almost) completely determined by DNA sequencing, it is not yet fully understood. Most (though probably not all) genes have been identified by a combination of high throughput experimental and bioinformatics approaches, yet much work still needs to be done to further elucidate the biological functions of their protein and RNA products. Recent results suggest that most of the vast quantities of noncoding DNA within the genome have associated biochemical activities, including regulation of gene expression, organization of chromosome architecture, and signals controlling epigenetic inheritance.There are an estimated 20,000-25,000 human protein-coding genes. The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further. Protein-coding sequences account for only a very small fraction of the genome (approximately 1.5%), and the rest is associated with non-coding RNA molecules, regulatory DNA sequences, LINEs, SINEs, introns, and sequences for which as yet no function has been elucidated.