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Analysis of expressed sequence tags from Cryptomeria japonica
Analysis of expressed sequence tags from Cryptomeria japonica

... the male partner in sexual reproduction, but also because it serves as a good model for investigations of cell growth and morphogenesis. A hybridization kinetics analysis of [ 3H]cDNA with poly(A)+ RNA revealed that between 20,000 and 24,000 different mRNA sequences are present in pollen of Tradesca ...
Posttranslational Protein Modiications in Plant
Posttranslational Protein Modiications in Plant

... Posttranslational modifications (PTMs) of proteins greatly expand proteome diversity, increase functionality, and allow for rapid responses, all at relatively low costs for the cell. PTMs play key roles in plants through their impact on signaling, gene expression, protein stability and interactions, ...
Posttranslational Protein Modiications in Plant
Posttranslational Protein Modiications in Plant

... Posttranslational modifications (PTMs) of proteins greatly expand proteome diversity, increase functionality, and allow for rapid responses, all at relatively low costs for the cell. PTMs play key roles in plants through their impact on signaling, gene expression, protein stability and interactions, ...
Insights into antibody catalysis: Structure of an oxygenation
Insights into antibody catalysis: Structure of an oxygenation

... Data Collection. Data sets were collected at - 165°C (Fabhapten) and 4°C (free Fab) using an R-AXIS II detector system mounted on a Rigaku RU-200 x-ray generator (50 kV and 100 mA). The reflections were indexed using DENZO 1.3.0 (written by Z. Otwinowski) and merged/scaled using the programs ROTAVAT ...
EXPRESSION OF EQUIVALENT CLONOTYPES IN BALB/c
EXPRESSION OF EQUIVALENT CLONOTYPES IN BALB/c

... structures at undetectable levels. For experiments involving induced antibodies, such as these, TLC is used in our laboratory only qualitatively to differentiate acidic and amide residues as the results are difficult to quantitate. All positions in these sequencer runs were initially analyzed by GC ...


Function of ribosomes and glutamyl-tRNA isoacceptors
Function of ribosomes and glutamyl-tRNA isoacceptors

... shown that ribosomes from regenerating muscle retain the increased activity which has been found for polysomes (as compared with controls) and that this increased activity is not abolished by salt washing of the ribosomes. Further, the increased activity appears to be due to a relatively higher effi ...
The role of multifunctional M1 metallopeptidases
The role of multifunctional M1 metallopeptidases

... of M1s require an active catalytic domain for function (Albiston et al., 2004; Peer et al., 2009). For example, M1 membrane association, trafficking to the plasma membrane, and M1-mediated trafficking of proteins to the plasma membrane require active catalytic domains (Ofner and Hooper, 2002; Albist ...
Chapter 5 - Red Hook Central Schools
Chapter 5 - Red Hook Central Schools

... Proteins have many structures, resulting in a wide range of functions • Proteins account for more than 50% of the dry mass of most cells. • Protein functions include structural support, storage, transport, cellular communications, movement, defense against foreign substances, and organic catalysts ...
The Structure and Function of Large Biological Molecules
The Structure and Function of Large Biological Molecules

...  Each cell has thousands of different macromolecules  Macromolecules vary among cells of an organism, vary more within a species, and vary even more between species  A huge variety of polymers can be built from a small set of monomers ...
Biology - Kenyon College
Biology - Kenyon College

Drug-excipient interaction and its importance in dosage form
Drug-excipient interaction and its importance in dosage form

food derived from insect-protected, glufosinate ammonium
food derived from insect-protected, glufosinate ammonium

... to be a healthy oil as it contains predominantly unsaturated fatty acids. Cottonseed oil has been in common use since the middle of the nineteenth century (Jones and King 1990, 1993) and achieved GRAS (Generally Recognised As Safe) status under the United States Federal Food Drug and Cosmetic Act be ...
Chloroplast phosphoglycerate kinase from Euglena gracilis
Chloroplast phosphoglycerate kinase from Euglena gracilis

... almost identical proteins of 423 amino acids that differ in only one residue. Asp422 of the second PGK protein (and also of the identical C-terminal fragment of the first unit) was replaced by Asn in the third PGK protein at the 3¢ end. At the nucleotide level sequence identity of the PGK segments is ...
Word - Food Standards Australia New Zealand
Word - Food Standards Australia New Zealand

Protein Structure Prediction Based on Neural Networks
Protein Structure Prediction Based on Neural Networks

... and knowledge of a protein’s 3D structure improves the analysis of protein functions, particularly for drug design [2]. Being aware of the 3D structure of a protein enables pharmacologists to select a binding protein to moderate its functions. Pharmacologists may choose a drug which is easy to synt ...
HIV-1 Vpr-chloramphenicol acetyltransferase fusion proteins
HIV-1 Vpr-chloramphenicol acetyltransferase fusion proteins

... 88CAT, were specifically detected in the corresponding cell lysates (Figure 1b, upper left panel, lanes 2–8). The molecular weight of the different Vpr-CAT fusion proteins ranged between approximately 29 kDa and 35 kDa. Analysis of viral lysates indicates that Vpr-CAT fusion proteins R1-42CAT, R1-80 ...
Green Fluorescent Protein
Green Fluorescent Protein

... variants are more enhanced than the wild type GFP and the result is that more fluorescence can be seen in mammalians. These variants can be used as reporter genes in order to learn about protein interactions, timing of cell cycle events, and much more. ...
Darnell, JC, Warren, ST and Darnell, RB: The fragile X mental retardation protein, FMRP, recognizes G-quartets. Mental Retardation and Developmental Disabilities Research Reviews 10:49-52 (2004).
Darnell, JC, Warren, ST and Darnell, RB: The fragile X mental retardation protein, FMRP, recognizes G-quartets. Mental Retardation and Developmental Disabilities Research Reviews 10:49-52 (2004).

... sites. This was shown by the significant number of putative G-quartets picked up by the RNABob program [Eddy; 2001; Gautheret et al., 1990] cited in Darnell et al. [2001] that did not bind FMRP when tested. It is likely that they do not fold into G-quartets because of competing structures in the RNA ...
Griffith_155
Griffith_155

... weights calculated from the sequences of the enzymes (e.g., 34,466 for the B. cereus PI-PLC). The value is higher than that observed by gel filtration ...
exam1ans_2007
exam1ans_2007

... iii) Briefly explain the effect of pH on the binding affinity. Your answer should clearly indicate how the interaction between the aminobenzene and the Fab fragment changes as a function of pH and how this affects the measured KD. You can assume that the pKa values of the aminobenzene and the sidech ...
Chromosomal rearrangements and protein globularity changes in
Chromosomal rearrangements and protein globularity changes in

... associated with high morbidity and mortality (Erhabor, Adewole & Ogunlade, 2006; Bidstrup et al., 2002). In parts of the world where the incidence of TB is high, TBM may occur in more than 10% of TB cases, especially among children and HIV infected individuals (Ige, Sogaolu & Ogunlade, 2005). The pa ...
Improving penicillin biosynthesis in Penicillium chrysogenum
Improving penicillin biosynthesis in Penicillium chrysogenum

... levels. More recently, also genetic engineering was introduced in strain improvement programs. These efforts have primarily focused on increasing the levels of (or introducing new) enzymes in the product pathway and on engineering of primary metabolism. At present, there is an urgent need for the de ...
Towards a Semantic W..
Towards a Semantic W..

Protein kinases of the human malaria parasite Plasmodium
Protein kinases of the human malaria parasite Plasmodium

... group respectively, whereas the C. elegans genome encodes 85 CK1-related genes. With the exception of the plant A. thaliana, all eukaryotes whose kinome has been characterised, from yeast to man, belong to the Opisthokonta phylogenetic group. As depicted in Fig. 1, this lineage represents only one s ...
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Interactome



In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.
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