Evolution of an ancient protein function involved in
... For dividing animal cells to generate and maintain organized tissues, the mitotic spindle must be oriented relative to the position of surrounding cells (Morin and Bellaı̈che, 2011; Gillies and Cabernard, 2011; Lu and Johnston, 2013; Cabernard and Doe, 2009; Williams et al., 2011). Cells that orient ...
... For dividing animal cells to generate and maintain organized tissues, the mitotic spindle must be oriented relative to the position of surrounding cells (Morin and Bellaı̈che, 2011; Gillies and Cabernard, 2011; Lu and Johnston, 2013; Cabernard and Doe, 2009; Williams et al., 2011). Cells that orient ...
E-mail: - HAL
... Many research groups have designed fragment libraries or structural alphabets to try to describe the local structural features of known protein structures more accurately.17-29 These libraries or alphabets correspond to finite sets of protein structural fragments. They can be differentiated accordin ...
... Many research groups have designed fragment libraries or structural alphabets to try to describe the local structural features of known protein structures more accurately.17-29 These libraries or alphabets correspond to finite sets of protein structural fragments. They can be differentiated accordin ...
Protein and DNA sequence determinants of
... evolutionary adaptation to extreme conditions. Together these results provide a complete picture of how compositions of proteomes and genomes in prokaryotes adjust to the extreme conditions of the environment. ...
... evolutionary adaptation to extreme conditions. Together these results provide a complete picture of how compositions of proteomes and genomes in prokaryotes adjust to the extreme conditions of the environment. ...
In-vitro Protein Production for Structure Determination with the Rapid
... genomes of Mycoplasma pneumoniae and Mycoplasma genitalium or structural homologs from other organisms. To achieve this goal, the Berkeley Structural Genomics Center is developing high-throughput methods for protein expression for use in X-ray and NMR structure determination. In collaboration with R ...
... genomes of Mycoplasma pneumoniae and Mycoplasma genitalium or structural homologs from other organisms. To achieve this goal, the Berkeley Structural Genomics Center is developing high-throughput methods for protein expression for use in X-ray and NMR structure determination. In collaboration with R ...
Experimental Analysis of the Rice Mitochondrial
... provide an in-depth proteome of rice shoot mitochondria covering both soluble and integral membrane proteins. Quantitative comparisons of mitochondria purified by density gradients and after further surface charge purification have been used to ensure that the proteins identified copurify with mitoc ...
... provide an in-depth proteome of rice shoot mitochondria covering both soluble and integral membrane proteins. Quantitative comparisons of mitochondria purified by density gradients and after further surface charge purification have been used to ensure that the proteins identified copurify with mitoc ...
Acquisition of 1,000 eubacterial genes physiologically transformed a
... groups (Fig. 2C) reveals that merely four eubacterial imports (three predicted membrane proteins and a glycosyl transferase) can be traced to their common ancestor, and that these are present in at most 6 of the 22 descendant genomes. Whereas 124 imports can be traced to the Ms/Mc/Mm common ancestor ...
... groups (Fig. 2C) reveals that merely four eubacterial imports (three predicted membrane proteins and a glycosyl transferase) can be traced to their common ancestor, and that these are present in at most 6 of the 22 descendant genomes. Whereas 124 imports can be traced to the Ms/Mc/Mm common ancestor ...
Table S1 Genes with similar expression patterns in Qing2
... Alanine transaminase (glutamic pyruvic transaminase); involved in alanine biosynthetic and catabolic processes; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies ...
... Alanine transaminase (glutamic pyruvic transaminase); involved in alanine biosynthetic and catabolic processes; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies ...
Expanding the Genetic Code with Unnatural Amino Acids
... Proteins are linear polymers of amino acids. They can contact one another and other macromolecules to form complexes, and some proteins are more rigid while others are flexible. In addition, the sequence of amino acids determines the folding of the protein, which is necessary for the protein's funct ...
... Proteins are linear polymers of amino acids. They can contact one another and other macromolecules to form complexes, and some proteins are more rigid while others are flexible. In addition, the sequence of amino acids determines the folding of the protein, which is necessary for the protein's funct ...
Organelle origins: Energy-producing symbionts
... would have occured many times. It seems more likely that hydrogenosomes are, in fact, highly reduced and modified descendants of mitochondria. A second possibility is that two or more independent endosymbiotic events occurred, one giving rise to the trichomonad hydrogenosomes and the other the mitoc ...
... would have occured many times. It seems more likely that hydrogenosomes are, in fact, highly reduced and modified descendants of mitochondria. A second possibility is that two or more independent endosymbiotic events occurred, one giving rise to the trichomonad hydrogenosomes and the other the mitoc ...
Analysis of TETRAKETIDE a-PYRONE
... Figure 1. Developmental Expression of TKPR1 and TKPR2 Proteins. (A) Protein extracts from different plant tissues were immunoblotted with polyclonal antibodies raised against each recombinant protein. Expression levels in roots (R), leaves (L), stems (S), flower buds (FB), and siliques (Si) were com ...
... Figure 1. Developmental Expression of TKPR1 and TKPR2 Proteins. (A) Protein extracts from different plant tissues were immunoblotted with polyclonal antibodies raised against each recombinant protein. Expression levels in roots (R), leaves (L), stems (S), flower buds (FB), and siliques (Si) were com ...
Engineering of factors determining alpha-amylase and
... CGTases which have a more bulky aromatic residue (Tyr or Phe) at this position, which is highly conserved. Characterization of the F196G mutant CGTase of T. thermosulfurigenes EM1 revealed that, for unknown reasons, apart from the F196G mutation, domain E as well as a part of domain D had become del ...
... CGTases which have a more bulky aromatic residue (Tyr or Phe) at this position, which is highly conserved. Characterization of the F196G mutant CGTase of T. thermosulfurigenes EM1 revealed that, for unknown reasons, apart from the F196G mutation, domain E as well as a part of domain D had become del ...
Proteomics of
... strongly predominate over their monomeric forms in boar seminal plasma. These interactions facilitate the formation of aggregated forms of proteins in the seminal plasma and probably the arrangement and remodeling of sperm coating proteins. It is interesting that the heparin-binding activity of aggr ...
... strongly predominate over their monomeric forms in boar seminal plasma. These interactions facilitate the formation of aggregated forms of proteins in the seminal plasma and probably the arrangement and remodeling of sperm coating proteins. It is interesting that the heparin-binding activity of aggr ...
Review Antibody flexibility observed in antigen binding and its
... Antibodies are well-known proteins that defend against bacterial and viral infections. At the molecular level, antibodies in solution are flexible and exist in populations of different structures with different energy levels which are important for antigen binding and immunological functions. In the ...
... Antibodies are well-known proteins that defend against bacterial and viral infections. At the molecular level, antibodies in solution are flexible and exist in populations of different structures with different energy levels which are important for antigen binding and immunological functions. In the ...
Evolution of Function in Protein Superfamilies, from a Structural
... evolutionary relationships hidden at the sequence level, since protein structure is conserved even after all trace of sequence similarity disappears. Detailed comparisons of unknown gene products with structural relatives will reveal regions of conservation and variation, and will guide experiments ...
... evolutionary relationships hidden at the sequence level, since protein structure is conserved even after all trace of sequence similarity disappears. Detailed comparisons of unknown gene products with structural relatives will reveal regions of conservation and variation, and will guide experiments ...
Preparing and Analyzing Expressed Sequence Tags (ESTs) Library
... 2.3. Sequence Analysis. For analysis of the raw EST data, the low-quality, adapter, and the vector sequences were removed with Phred software [14, 15] (CodonCode Corp., Dedham, MA). The remaining EST sequences were reprocessed by using “cross-match” program which is application of Phrap for the vect ...
... 2.3. Sequence Analysis. For analysis of the raw EST data, the low-quality, adapter, and the vector sequences were removed with Phred software [14, 15] (CodonCode Corp., Dedham, MA). The remaining EST sequences were reprocessed by using “cross-match” program which is application of Phrap for the vect ...
Amino Acids And Protein Ppt
... They form about 30% of total body proteins. • There are more than 20 types of collagens, the most common type is collagen I which constitutes about 90% of cell collagens. • Structure of collagen: three helical polypeptide chains (trimeric) twisted around each other forming triplet-helix molecule. • ...
... They form about 30% of total body proteins. • There are more than 20 types of collagens, the most common type is collagen I which constitutes about 90% of cell collagens. • Structure of collagen: three helical polypeptide chains (trimeric) twisted around each other forming triplet-helix molecule. • ...
Recombinant expression and characterisation of monofunctional S-
... apparent Michaelis constant for ornithine was found to be 52 J.1M and crosshybridisation studies with mouse OOC antibodies suggested some structural differences in comparison with the mammalian enzyme (Assara( et al., 1988). Muller et al. (2000) provided conclusive data that both malarial decarboxyl ...
... apparent Michaelis constant for ornithine was found to be 52 J.1M and crosshybridisation studies with mouse OOC antibodies suggested some structural differences in comparison with the mammalian enzyme (Assara( et al., 1988). Muller et al. (2000) provided conclusive data that both malarial decarboxyl ...
Protein structural class prediction using predicted secondary
... which determines its function. Structure prediction is an important area of research since it helps one to understand or discover the function of unknown proteins. Details of the 3D structures of proteins are very complicated, irregular, and expensive to determine. Researchers try to find out overa ...
... which determines its function. Structure prediction is an important area of research since it helps one to understand or discover the function of unknown proteins. Details of the 3D structures of proteins are very complicated, irregular, and expensive to determine. Researchers try to find out overa ...
Interactome
In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.