Jürgen Sühnel 3D Structures of Biological Macromolecules
... • Repeat this procedure to locate all of the helical regions in the sequence. • Scan through the peptide and identify a region where 3 out of 5 of the residues have a value of P(b-sheet) > 100. That region is declared as a beta-sheet. Extend the sheet in both directions until a set of four contiguou ...
... • Repeat this procedure to locate all of the helical regions in the sequence. • Scan through the peptide and identify a region where 3 out of 5 of the residues have a value of P(b-sheet) > 100. That region is declared as a beta-sheet. Extend the sheet in both directions until a set of four contiguou ...
Functional and structural roles of parasite-specific inserts in the bifunctional S-adenosylmethionine decarboxylase/ornithine
... AdoMetDClODC were expressed as Strep-Tag fusion proteins as described in Chapter 3, section 3.2.2 (Krause, et al., 2000; Miiller, et al., 2000; Wrenger, et al., 2001). Mutant forms of PfAdoMetDC/ODC with individual deletion of the parasite-specific inserts, as well as single and combined insert dele ...
... AdoMetDClODC were expressed as Strep-Tag fusion proteins as described in Chapter 3, section 3.2.2 (Krause, et al., 2000; Miiller, et al., 2000; Wrenger, et al., 2001). Mutant forms of PfAdoMetDC/ODC with individual deletion of the parasite-specific inserts, as well as single and combined insert dele ...
and related proteins three-dimensional structure in a large family of
... (Siezen et al., 1991). Greer (1990) coined the term “structurally conserved regions,” or SCRs, to describe common regions of proteins belonging to the same family, based on the superposition of their 3D structures. Similarly, he used the term “variable regions,” or VRs, to describe those regions whe ...
... (Siezen et al., 1991). Greer (1990) coined the term “structurally conserved regions,” or SCRs, to describe common regions of proteins belonging to the same family, based on the superposition of their 3D structures. Similarly, he used the term “variable regions,” or VRs, to describe those regions whe ...
Molecules of Life - Morgan Community College
... What Determines Protein Conformation? • In addition to primary structure, physical and chemical conditions can affect conformation • Alternations in pH, salt concentration, temperature, or other environmental factors can cause a protein to unravel • This loss of a protein’s native conformation is c ...
... What Determines Protein Conformation? • In addition to primary structure, physical and chemical conditions can affect conformation • Alternations in pH, salt concentration, temperature, or other environmental factors can cause a protein to unravel • This loss of a protein’s native conformation is c ...
Topology Prediction of Membrane Proteins
... All polar amide and carbonyl groups in the backbone are hydrogen bonded internally within the helix. This lowers the cost of transferring polar entities into the hydrocarbon interior and makes the conformation energetically stable. Another stabilizing factor is the enrichment of aromatic residues (T ...
... All polar amide and carbonyl groups in the backbone are hydrogen bonded internally within the helix. This lowers the cost of transferring polar entities into the hydrocarbon interior and makes the conformation energetically stable. Another stabilizing factor is the enrichment of aromatic residues (T ...
Lehninger-Principles-of-Biochemistry-Nelson-5th-Edition-1
... What is the underlying, organizing biochemical principle that results in the chemical similarity of virtually all living things? Given this biochemical similarity, how is the structural and functional diversity of living things possible? Ans: Living things are composed primarily of macromolecules, p ...
... What is the underlying, organizing biochemical principle that results in the chemical similarity of virtually all living things? Given this biochemical similarity, how is the structural and functional diversity of living things possible? Ans: Living things are composed primarily of macromolecules, p ...
Ch 5 Biomolc Strc & Fxn
... • These trans fats may contribute more than saturated fats to cardiovascular disease!! • Humans & mammals store fat in adipose cells • The major function of fats is energy storage • Adipose tissue also cushions vital organs and insulates the body Copyright © 2008 Pearson Education, Inc., publishing ...
... • These trans fats may contribute more than saturated fats to cardiovascular disease!! • Humans & mammals store fat in adipose cells • The major function of fats is energy storage • Adipose tissue also cushions vital organs and insulates the body Copyright © 2008 Pearson Education, Inc., publishing ...
Lecture 5 Tues 4-11-06
... a. Differ from Mt because they are surrounded by only a single membrane, do not contain DNA or ribosomes, & acquire all their proteins by selective import from the cytosol b. Post-translational mechanism of protein import like that of the nucleus Does not involve unfolding of the cargo Involves a so ...
... a. Differ from Mt because they are surrounded by only a single membrane, do not contain DNA or ribosomes, & acquire all their proteins by selective import from the cytosol b. Post-translational mechanism of protein import like that of the nucleus Does not involve unfolding of the cargo Involves a so ...
PLoS Pathogens
... Despite several commonalities, T3SEs are evolutionarily diverse and highly variable in their distribution, both within and among species [9]. Their intimate interactions with host factors expose them to very strong selective pressures [15,16] resulting in their rapid evolutionary turnover [17,18]. G ...
... Despite several commonalities, T3SEs are evolutionarily diverse and highly variable in their distribution, both within and among species [9]. Their intimate interactions with host factors expose them to very strong selective pressures [15,16] resulting in their rapid evolutionary turnover [17,18]. G ...
3.2 Breeding of corn line DAS-40278-9
... quizalofop-P-ethyl. This has been achieved through the introduction of the aad-1 gene, from Sphingobium herbicidovorans, expressing the enzyme aryloxyalkanoate dioxygenase (AAD-1). In conducting a safety assessment of food derived from herbicide-tolerant corn line DAS-40278-9, a number of criteria h ...
... quizalofop-P-ethyl. This has been achieved through the introduction of the aad-1 gene, from Sphingobium herbicidovorans, expressing the enzyme aryloxyalkanoate dioxygenase (AAD-1). In conducting a safety assessment of food derived from herbicide-tolerant corn line DAS-40278-9, a number of criteria h ...
The Secrets To Youthful Nutrition
... to stay. Leading clinical nutritionists (I was fortunate enough to study under one of the leading authorities in GI research, Dr. Anthony Leeds) have actively researched low GI diets and have proven that it has many positive medical benefits, such as reducing adultonset diabetes and heart disease. A ...
... to stay. Leading clinical nutritionists (I was fortunate enough to study under one of the leading authorities in GI research, Dr. Anthony Leeds) have actively researched low GI diets and have proven that it has many positive medical benefits, such as reducing adultonset diabetes and heart disease. A ...
Divergence and Convergence in Enzyme Evolution
... the inositol ring with a likely involvement of a phosphohistidine intermediate (29), whereas mycosporine glycine synthetase has a 4-deoxygadusol substrate that contains a hydroxyl group attached to an aromatic ring (30). These examples reveal substantial plasticity of the ATP-grasp fold that allows ...
... the inositol ring with a likely involvement of a phosphohistidine intermediate (29), whereas mycosporine glycine synthetase has a 4-deoxygadusol substrate that contains a hydroxyl group attached to an aromatic ring (30). These examples reveal substantial plasticity of the ATP-grasp fold that allows ...
blast
... • Primer BLAST – uses Primer3 to design PCR primers • Genomic BLAST – for alignments against completed genomes • VecScreen – for detecting cloning vector contamination in sequenced data. see last weeks handout for rest of them ...
... • Primer BLAST – uses Primer3 to design PCR primers • Genomic BLAST – for alignments against completed genomes • VecScreen – for detecting cloning vector contamination in sequenced data. see last weeks handout for rest of them ...
Chapter 3 - GEOCITIES.ws
... notes!)_____________________________________________ ___________________________________________________ ___________________________________________________ ___________________________________________________ ___________________________________________________ Organisms ...
... notes!)_____________________________________________ ___________________________________________________ ___________________________________________________ ___________________________________________________ ___________________________________________________ Organisms ...
High Resolution Two-Dimensional Electrophoresis of Proteins*
... detected and quantified by autoradiography. The reproducibility of the separation is sufficient to permit each spot on surface of the gel. Isoelectric focusing and a discontinuous SDS’ gel system (1) were chosen because of the high resolution of each one separation to be matched with a spot on a dif ...
... detected and quantified by autoradiography. The reproducibility of the separation is sufficient to permit each spot on surface of the gel. Isoelectric focusing and a discontinuous SDS’ gel system (1) were chosen because of the high resolution of each one separation to be matched with a spot on a dif ...
Soy Protein Based Green Composite: A Review
... causing the protein to precipitate out of aqueous solution [14]. It has been found that the soy protein could not form a film at or near its isoelectric point (pH 4.5) due to the coagulation. However, proteins can be denatured and unfolded at pH values away from their isoelectric point, thus exposin ...
... causing the protein to precipitate out of aqueous solution [14]. It has been found that the soy protein could not form a film at or near its isoelectric point (pH 4.5) due to the coagulation. However, proteins can be denatured and unfolded at pH values away from their isoelectric point, thus exposin ...
Selective Amino Acid-Type Labeling(continued)
... undesired amino acids (also called as “isotope scrambling”).3 This happens due to metabolic conversion of one amino acid to another in the bio-synthetic pathway of the cell. The problem becomes more severe for amino acids higher up or intermediates in the metabolic pathway such as Asp, Glu and Gln ( ...
... undesired amino acids (also called as “isotope scrambling”).3 This happens due to metabolic conversion of one amino acid to another in the bio-synthetic pathway of the cell. The problem becomes more severe for amino acids higher up or intermediates in the metabolic pathway such as Asp, Glu and Gln ( ...
A Novel Role for Vitamin K1 in a Tyrosine Phosphorylation
... type III and immunoglobulin motifs common to extracellular matrix proteins, neural cell adhesion molecules, and cell surface receptors with tyrosine kinase or phosphatase activities (13, 14). It is believed that these RTKs may be bifunctional, acting both as cell adhesion proteins and as components ...
... type III and immunoglobulin motifs common to extracellular matrix proteins, neural cell adhesion molecules, and cell surface receptors with tyrosine kinase or phosphatase activities (13, 14). It is believed that these RTKs may be bifunctional, acting both as cell adhesion proteins and as components ...
Safety Assessment of Soy Proteins and Peptides as Used in
... 71 kDa) and β (ca 50 kDa). The 11S globulin is a hexamer, and is made up of five different subunits, each of which consists of an acidic subunit A (ca 35 kDa) and a basic subunit B (ca 20 kDa), linked by a disulfide bond. The 11S globulin was found to dissociate into 2S, 3S or 7S forms in solutions ...
... 71 kDa) and β (ca 50 kDa). The 11S globulin is a hexamer, and is made up of five different subunits, each of which consists of an acidic subunit A (ca 35 kDa) and a basic subunit B (ca 20 kDa), linked by a disulfide bond. The 11S globulin was found to dissociate into 2S, 3S or 7S forms in solutions ...
What are Membranes?
... Ankyrin is anchored in the membrane by a covalently bound palmitoyl side chain (see Figure 11-14). Spectrin, a long, filamentous protein, is cross-linked at junctional complexes containing actin. A network of cross-linked spectrin molecules attached to the cytoplasmic face of the plasma membrane sta ...
... Ankyrin is anchored in the membrane by a covalently bound palmitoyl side chain (see Figure 11-14). Spectrin, a long, filamentous protein, is cross-linked at junctional complexes containing actin. A network of cross-linked spectrin molecules attached to the cytoplasmic face of the plasma membrane sta ...
Research Communications
... a degradation product of fermentation or not, we compared the HPTLC fingerprint (see Supplementary Data VII online) of methanolic extract of starting materials of pippalyasava with the methanolic extract of the fermented pippalyasava. The HPTLC fingerprint confirmed that the compound benzoic acid wa ...
... a degradation product of fermentation or not, we compared the HPTLC fingerprint (see Supplementary Data VII online) of methanolic extract of starting materials of pippalyasava with the methanolic extract of the fermented pippalyasava. The HPTLC fingerprint confirmed that the compound benzoic acid wa ...
Interactome
In molecular biology, an interactome is the whole set of molecular interactions in a particular cell. The term specifically refers to physical interactions among molecules (such as those among proteins, also known as protein-protein interactions) but can also describe sets of indirect interactions among genes (genetic interactions). Mathematically, interactomes are generally displayed as graphs.The word ""interactome"" was originally coined in 1999 by a group of French scientists headed by Bernard Jacq. Though interactomes may be described as biological networks, they should not be confused with other networks such as neural networks or food webs.