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Protein Synthesis
Protein Synthesis

... of insulin protein. Suppose a person has a mutation in his/her DNA and the first triplet for the insulin gene reads T A T instead of T A G which is the normal gene for insulin. Will the person with this mutation be diabetic? A. Yes, because any mutation will cause disease. B. Yes, because the insuli ...
PROTEIN SYNTHESIS
PROTEIN SYNTHESIS

... Types of RNA • mRNA – messenger RNA – carries copy of genetic instructions to the rest of the cell – the instructions tell the cell how to assemble the amino acids for making proteins ...
Jalview Homework
Jalview Homework

... 6. You should see all of the sequences stacked on top of each other in the window that pops up. Go to the “Web Service” option of the window and select “ClustalW Multiple Alignment”. You must be connected to the internet in order for the data to be sent to the server that will perform the multiple a ...
Protein Synthesis
Protein Synthesis

... These nucleotides are linked together to form chains or strands. ...
Slides
Slides

...  They are large molecules (few 100s to several 1000s of atoms)  They are made of building blocks (amino acids) drawn from a small “library” of 20 amino-acids  They have an unusual kinematic structure: long serial linkage (backbone) with short side-chains ...
Dairy Jepoardy 3
Dairy Jepoardy 3

... Term that describes a gene or DNA fragment known to be linked to a gene of interest. ...
第一次课件第八章
第一次课件第八章

... effective when the DNA is joined into a circle by a protein bridge. An enhancer and promoter on separate circular DNAs do not interact, but can interact when the two molecules are catenated. ...
Discovery of potent inhibitors of the epigenetic cancer target PRMT4
Discovery of potent inhibitors of the epigenetic cancer target PRMT4

File
File

... Protein Structure p.356 Proteins are made up of one or more chains of small units called amino acids.  There are 20 different amino acids.  Some chains are very long, containing 600 amino acids.  Usually proteins have an average of 100-200 amino acids. ...
E1-3 NotesProtein Synth
E1-3 NotesProtein Synth

... make proteins. 2. Transcription – where genetic info copies from DNA to RNA 3. Steps – a. RNA binds to regions of DNA that make a single gene (in eukaryotes) b. Nitrogen bases pair up (Uracil with adenine/ guanine with cytosine) c. Single strand made until single gene copied D. Products of Transcrip ...
Chapter 4 Cellular Metabolism
Chapter 4 Cellular Metabolism

... Energy: ATP is ___adenosine tri-phosphate_. It stores the energy for every reaction in the body. Where exactly is this energy stored in the ATP molecule? High chemical energy bonds Cellular Respiration: is the process that releases the energy in the chemical bonds of the energy nutrients and stores ...
EXPLORING PROTEIN STRUCTURE
EXPLORING PROTEIN STRUCTURE

... cross-linked by disulfide bonds. Source:http://www.prideofindia.net/images/nails.jpg http://opbs.okstate.edu/~petracek/2002%20protein%20structure%20function/CH06/Fig%2006-12.GIF ...
GTAC bioinformatics task 4 presentation
GTAC bioinformatics task 4 presentation

... cross-linked by disulfide bonds. Source:http://www.prideofindia.net/images/nails.jpg http://opbs.okstate.edu/~petracek/2002%20protein%20structure%20function/CH06/Fig%2006-12.GIF ...
Characterization and prediction of drug binding sites in proteins
Characterization and prediction of drug binding sites in proteins

Bio 210 Cell Chemistry Lecture 5 “Proteins and Nucleic Acids”
Bio 210 Cell Chemistry Lecture 5 “Proteins and Nucleic Acids”

bioinformatics
bioinformatics

... The study of the origin & descent of spp.and their change over time. New insight to molecular basis of disease. Investigating the function of homologs of a disease gene. Homology:two genes sharing a common evolut.history. Finding evolut.relationships between diff.forms of life. Closely related orgni ...
Biomolecules are organic molecules built and used inside of cells
Biomolecules are organic molecules built and used inside of cells

a sample task
a sample task

... amino acids in a polypeptide chain. For example, the pancreatic hormone insulin has two polypeptide chains, A and B, shown in the diagram below. Each chain has its own set of amino acids, assembled in a particular order. For instance, the sequence of the A chain starts with glycine at the N-terminus ...
MEMBRANES Fluid mosaic of phopholipid bilayer, cholesterol
MEMBRANES Fluid mosaic of phopholipid bilayer, cholesterol

... Active Transport: facilitated movement against concentration gradient Requires not only Carrier Proteins, but also E in form of ATP In what class of macromolecule is ATP ...
Document
Document

... carbohydrates the night before a game? ...
L2_Protein Structure_12_Jan
L2_Protein Structure_12_Jan

... acid polymer is neither functional nor energetically favorable  folding! ...
cytology_chemicals
cytology_chemicals

...  Both are steroids with four fused carbon rings, but they differ in the functional groups attached to the rings.  These then interact with different targets in the body. ...
document
document

... working on the structure of DNA in the 1950’s also. Using information from Chargaff, Franklin, and other scientists, they put together a 3-D model of DNA. Their model was a double helix, with Hbonded nitrogenous bases holding the strands together. The won the Nobel Prize for their work. ...
Carbon Isomers
Carbon Isomers

... – Functional units within a larger structure – Most proteins made of multiple domains that perform different parts of the protein’s function ...
Learning Objectives handouts
Learning Objectives handouts

... 2. Distinguish between monomers and polymers. 3. Draw diagrams to illustrate condensation and hydrolysis reactions. Carbohydrates Serve as Fuel and Building Material 4. Distinguish between monosaccharides, disaccharides, and polysaccharides. 5. Describe the formation of a glycosidic linkage. 6. Dist ...
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Two-hybrid screening



Two-hybrid screening (also known as yeast two-hybrid system or Y2H) is a molecular biology technique used to discover protein–protein interactions (PPIs) and protein–DNA interactions by testing for physical interactions (such as binding) between two proteins or a single protein and a DNA molecule, respectively.The premise behind the test is the activation of downstream reporter gene(s) by the binding of a transcription factor onto an upstream activating sequence (UAS). For two-hybrid screening, the transcription factor is split into two separate fragments, called the binding domain (BD) and activating domain (AD). The BD is the domain responsible for binding to the UAS and the AD is the domain responsible for the activation of transcription. The Y2H is thus a protein-fragment complementation assay.
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