• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Cloning and Sequencing of DNA from a Plasmid Library
Cloning and Sequencing of DNA from a Plasmid Library

... cytochrome c7 protein sequence data are being used to investigate cd and c7 cytochromes. Degenerate probe HEM1B, based on 7 amino acids including the heme 1 binding site of cytochrome c7 found in G. metallireducens hybridized with a clone containing a 1.83 kb insert (GenBank accession AY167567). Thi ...
The CENTRAL DOGMA in Biology:
The CENTRAL DOGMA in Biology:

... compounds that have “side chains” that make the protein fold into complicated shapes. There are ______ different amino acids (the human body can make some amino acids, others must obtained from food).  A typical protein may contain __________________ or more amino acids.  Each protein has its own ...
Plasma membrane
Plasma membrane

... Tonicity : the ability of a solution to cause a cell to gain or lose water - Isotonic: no net movement of water across the membrane (normal). - Hypertonic : the cell loses water to its environment (crenation). - Hypotonic : the cell gains water from its environment (lysis). ...
Operon
Operon

... metabolite that triggers transcription of the lac operon. Unlike allolactose, the sulfur (S) atom creates a chemical bond which is non-hydrolyzable by the cell, preventing the cell from "eating up" or degrading the inductant. IPTG induces activity of betagalactosidase, an enzyme that promotes lactos ...
1 Which of structures below stands for D
1 Which of structures below stands for D

... bridges) and the formation of a new set of intersubunit interactions. This change3 in subunit interactions initiates a change in conformation of the non-oxygenated subunits. The net result of these conformational changes is to greatly increase the affinity for oxygen of these hemoglobin subunits. 4. ...
Ch 5 Activity List File
Ch 5 Activity List File

... 9. Identify an ester linkage and describe how it is formed. 10. Distinguish between saturated and unsaturated fats. 11. Name the principal energy storage molecules of plants and animals. 12. Distinguish between a protein and a polypeptide. 13. Explain how a peptide bond forms between two amino acids ...
國立嘉義大學九十二學年度
國立嘉義大學九十二學年度

... (1) Differences in sizes of DNA fragments (RFLPs). (2) Footprinting. (3) Site directed mutations. (4) DNA with proteins bound moves slower in gel electrophoresis. (5) More than one of these is important in using DNA for forensic identification. 4. The following is useful for determining which amino ...
How life works
How life works

... particular cell type they are fixed (except some pluripotent cells). It was always thought that what genes were expressed was written into your DNA as well – your DNA set what genes you have and which would be expressed. The only change could come from random mutations. But recent developments sugge ...
lecture 1
lecture 1

... Chain of nucleotides has alternating sugar and phosphate components, called the “sugarphosphate backbone.” Nitrogenous bases stick off backbone at regular intervals. ...
Unit 1 Ch. 1, 17, 18. WHAT IS BIOLOGY?
Unit 1 Ch. 1, 17, 18. WHAT IS BIOLOGY?

... b Initiation, the first stage of translating mRNA, will start when an initiator tRNA binds to a small ribosomal subunit. ...
슬라이드 1
슬라이드 1

...  weak interaction  Hydrophobic interaction between nonpolar side chains  Hydrogen bond between polar side chains and peptide bonds ...
Gene Expression
Gene Expression

... function of the protein.  The DNA code holds the key for the sequence of amino acids for each protein. ...
protein - The Robinson Group – University of Nottingham
protein - The Robinson Group – University of Nottingham

... experimental approaches to the analysis of protein folding kinetics and the application of site-directed mutagenesis. A range of experimental spectroscopic techniques will be introduced to probe protein structure and stability based on secondary structure and tertiary interactions and to probe the n ...
Lecture 6
Lecture 6

... c. There exist two cycles: replication and translation  they form one big cycle IV. DNA a. Only one proper base pairing: G-C, A-T b. Fourth degree interaction by hydrogen bonds c. Replication: two copies, same info, constraints on the process exist d. Need ATP to have process proceed V. Conclusion ...
Serum Total Protein
Serum Total Protein

Folds
Folds

... a protein of 100 aa may have 20100 possible sequences/conformations, but an estimate says that there are only ~1000 folds in nature (we know a few hundreds of them so far); if we consider only the # of human genes (even without splice variants) there should be more than ~30,000 individual conformati ...
Protein Structure
Protein Structure

... Linus Pauling defined the two main protein secondary structures in the 1950s: alpha helix and beta sheet. – There are other related structures: for instance, the alpha helix has hydrogen bonds between the backbone –NH group of one alpha-carbon to the backbone C=O group of the alpha-carbon 4 residues ...
Proteins
Proteins

... • If the non-amino acid part of the protein is important to its function, it is called a prosthetic group. • Large organic molecules (vitamins) comjugated to proteins are coenzymes. • Be familiar with the terms: glycoprotein, lipoprotein, nucleoprotein, phosphoprotein, metalloprotein, hemoprotein, f ...
How Genes Are Regulated
How Genes Are Regulated

... • Describe how prokaryotic gene expression occurs at the transcriptional level • Understand that eukaryotic gene expression occurs at the epigenetic, transcriptional, post-transcriptional, translational, and post-translational levels For a cell to function properly, necessary proteins must be synthe ...
Dna Mutations
Dna Mutations

... • change to a codon to one that encodes a different amino acid and cause a small change in the protein produced • change a codon to one that encodes the same amino acid and causes no change in the protein produced. These are called silent mutations. • change an amino-acid-coding codon to a single "s ...
NUTRITIONAL REGULATIN OF GROWTH
NUTRITIONAL REGULATIN OF GROWTH

... after being deprived of nutrients will deposit more fat If fed a low level of nutrition late in production, then they will produce leaner carcasses Figure 11.9 and table 11.6 & 7 ...
Estimating the Recovery Kinetics of tER Sites
Estimating the Recovery Kinetics of tER Sites

... Through fluorescence recovery after photobleaching (FRAP) imaging techniques the rate proteins attached to specific genes transfer between tER sites is observable, allowing one to infer protein kinetics and behaviors. It is important to estimate a function accurately describing the recovery kinetics ...
Detailed characterization of the interactions between hepatitis C virus and host proteins.
Detailed characterization of the interactions between hepatitis C virus and host proteins.

... between HCV and host will determine the outcome of the viral infection. To characterize these processes in details, several novel viral-host interactions have been identified through yeast-twohybrid screen, proteomic and bioinformatic approaches. For the first part of the project, we aim to determin ...
Name Date Ch 3. Carbon and the Molecular Diversity of Life
Name Date Ch 3. Carbon and the Molecular Diversity of Life

... 25. What types of environments can affect the protein structure? What happens to the protein when they are exposed to these environments? ...
Influenza A H3N2 (A/Perth/16/2009) Hemagglutinin / HA
Influenza A H3N2 (A/Perth/16/2009) Hemagglutinin / HA

... AI451697; ha; ihj; nmf4; sph; Spna-1; Spna1 ...
< 1 ... 404 405 406 407 408 409 410 411 412 ... 466 >

Two-hybrid screening



Two-hybrid screening (also known as yeast two-hybrid system or Y2H) is a molecular biology technique used to discover protein–protein interactions (PPIs) and protein–DNA interactions by testing for physical interactions (such as binding) between two proteins or a single protein and a DNA molecule, respectively.The premise behind the test is the activation of downstream reporter gene(s) by the binding of a transcription factor onto an upstream activating sequence (UAS). For two-hybrid screening, the transcription factor is split into two separate fragments, called the binding domain (BD) and activating domain (AD). The BD is the domain responsible for binding to the UAS and the AD is the domain responsible for the activation of transcription. The Y2H is thus a protein-fragment complementation assay.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report