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FATS - Typepad
FATS - Typepad

... MEAT, FISH, BEANS DAIRY (EGGS, CHEESE, MILK) MILK – YEICH!!!!!!!!!!!!!!!! ALL FOR BUILDING, REPAIRING, ACTING AS ENZYMES, BRINGING NUTRIENTS IN TO THE CELL ...
electrophoresis_power_point
electrophoresis_power_point

... molecules on the basis of their charge and size. The charged macromolecules migrate across a span of gel because they are placed in an electrical field. The gel acts as a sieve to to retard the passage of molecules according to their size and shape. ...
Gene Section NONO  non-POU  domain  containing,  octamer- binding
Gene Section NONO non-POU domain containing, octamer- binding

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Table S6: Domains present in the primary network generated from

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Simple Sugars
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pdbe.org
pdbe.org

... is unusual, but this residue is conserved throughout the Als family. The residue seems to be essential to the structure of Als9-2 as well as its function as engineering mutations to this residue caused the protein to misfold or not express at all. It is clear from View 3 that the binding cavity is m ...
organic molecules webquest
organic molecules webquest

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organic macromolecules webquest
organic macromolecules webquest

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Protein Quality Control Mechanisms and Protein

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Biochemistry I, Spring Term 2001 - Second Exam answer key
Biochemistry I, Spring Term 2001 - Second Exam answer key

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Disparate proteins use similar architectures to damage membranes

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GluR-A C-terminal 10 residues constitute a binding motif

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Richards, F.M. The Protein Folding Problem. Scientific American, pp
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Computational Molecular Biology 2012
Computational Molecular Biology 2012

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Gene Section PTPN21 (protein tyrosine phosphatase, non- receptor type 21)
Gene Section PTPN21 (protein tyrosine phosphatase, non- receptor type 21)

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Medical School Biochemistry
Medical School Biochemistry

... MOST APPROPRIATE ANSWER ...
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Western blot



The western blot (sometimes called the protein immunoblot) is a widely used analytical technique used to detect specific proteins in a sample of tissue homogenate or extract. It uses gel electrophoresis to separate native proteins by 3-D structure or denatured proteins by the length of the polypeptide. The proteins are then transferred to a membrane (typically nitrocellulose or PVDF), where they are stained with antibodies specific to the target protein. The gel electrophoresis step is included in western blot analysis to resolve the issue of the cross-reactivity of antibodies.There are many reagent companies that specialize in providing antibodies (both monoclonal and polyclonal antibodies) against tens of thousands of different proteins. Commercial antibodies can be expensive, although the unbound antibody can be reused between experiments. This method is used in the fields of molecular biology, immunogenetics and other molecular biology disciplines. A number of search engines, such as CiteAb, Antibodypedia, and SeekProducts, are available that can help researchers find suitable antibodies for use in western blotting.Other related techniques include dot blot analysis, immunohistochemistry and immunocytochemistry where antibodies are used to detect proteins in tissues and cells by immunostaining, and enzyme-linked immunosorbent assay (ELISA).The method originated in the laboratory of Harry Towbin at the Friedrich Miescher Institute. The name western blot was given to the technique by W. Neal Burnette and is a play on the name Southern blot, a technique for DNA detection developed earlier by Edwin Southern. Detection of RNA is termed northern blot and was developed by George Stark at Stanford.
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