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Basic amino acid in the pathogenesis of caries
Basic amino acid in the pathogenesis of caries

... acids, 9 of them regularly present, and the others found occasionally. Liappis and Hildebrand (6 ) determined free amino acids in saliva in relation to caries, but did not find any significant quali­ tative or quantitative differences in the concen­ trations of individual free amino acids. A study o ...
ref. #28 of the TIBS article
ref. #28 of the TIBS article

... of dog pancreas microsomes, and MGD values were obtained by determining the number of residues between a given reference residue at the lumenal end of the TMH and the glycosylation acceptor Asn needed to get half-maximal glycosylation. Calibration: the phage M13 coat protein We have shown that the N ...
Coevolution theory of the genetic code at age thirty
Coevolution theory of the genetic code at age thirty

... and Trp share UGN codons because they were both derived from Ser is supported by homology between biosynthetic enzymes for Cys and Trp.(74) In addition, it is known that tRNAdependent pretran syntheses could come to be replaced in time by evolved tRNA-independent reactions, e.g. the synthesis of Gln ...
Document
Document

... Also, the contribution of the different parts to whole body protein changes over time with an increasing contribution of the carcass and of whole blood, and a decreasing contribution of offals[2]. Although hair represents only a small fraction of whole body protein, its high Cys content results in t ...
`Hybrid Protein Model`for optimally defining 3D protein structure
`Hybrid Protein Model`for optimally defining 3D protein structure

... the PBs is 0.58 Å. The 16 PBs are labeled by letters from a to p. PB m is the prototype of the central α-helix and d the prototype of the central β-sheet. PBs a to c primarily represent β-sheet N-caps and e and f , C-caps; g to j are specific to coils, k and l to the N-caps, and n to p to the C-cap ...
Purine metabolism - mustafaaltinisik.org.uk
Purine metabolism - mustafaaltinisik.org.uk

... XDP + YTP ...
amino-acids - ChemConnections
amino-acids - ChemConnections

Evolution - Amino Acid wksht
Evolution - Amino Acid wksht

all plant protein - frequently asked questions
all plant protein - frequently asked questions

... • Endurance Athlete: 1.2-1.4 g/kg body weight • Strength Athlete: 1.2-1.7 g/kg body weight Some athletes prefer to supplement their diet with whey protein because it is more rapidly emptied from the stomach resulting in a faster rise in plasma amino acids and protein synthesis. This characteristic m ...
Theranostics Evolution- and Structure
Theranostics Evolution- and Structure

... describing the relationship between non-synonymous SNPs (nsSNPs) and the diseases associated with them. Although most variations in protein sequence are predicted to have little or no effect on protein function, some nsSNPs are known to be associated with disease. These disease-associated nsSNPs hav ...
(De)regulation of key enzyme steps in the shikimate pathway and
(De)regulation of key enzyme steps in the shikimate pathway and

... Prephenate dehydratase (PDT), chorismate mutase (CM) and 3-deoxy-D-arabino-7-heptulosonate 7-phosphate (DAHP) synthase are key regulatory enzymes in aromatic amino acid biosynthesis in the actinomycete Amycolatopsis methanolica. Deregulated, feedback-control-resistant mutants were isolated by incuba ...
Structure of human cystathionine synthase: a
Structure of human cystathionine synthase: a

... group of Cys52 and the Ne2 atom of His65 axially coordinate the iron in the heme. This result con®rms an earlier ®nding that the 5th and 6th coordination positions of the heme are a thiolate and a nitrogenous group, respectively (Omura et al., 1984). Unlike the globins or cytochrome c peroxidase, th ...
AlgPred: prediction of allergenic proteins and mapping of
AlgPred: prediction of allergenic proteins and mapping of

... used as an input vector of dimension 20 for training and testing of SVM (33–35). The performance of SVM-based methods has been optimized by tuning SVM parameters, in order to achieve maximum accuracy with nearly equal sensitivity and specificity. As shown in Table 1, we achieved accuracy around 85% ...
Mutational effects on protein structure and function Jonas Carlsson Link¨
Mutational effects on protein structure and function Jonas Carlsson Link¨

... The amyloid formation of IAPP (islet amyloid polypeptide) is strongly connected to diabetes and has been studied using both molecular dynamics and Monte Carlo energy minimization. The effects of mutations on the amount and speed of amyloid formation were investigated using three approaches. Applying ...
Amino Acid Oxidation, the Production of Urea, and Amino Acid
Amino Acid Oxidation, the Production of Urea, and Amino Acid

... cycle and the α-ketoglutarate that results enters the TCA Cycle followed by gluconeogenesis with the resulting glucose being sent back to the tissues (very likely possibility). Alanine from the tissues is transported into the liver mitochondrial matrix where it is transaminated with αketoglutarate a ...
Chloroplast phosphoglycerate kinase from Euglena gracilis
Chloroplast phosphoglycerate kinase from Euglena gracilis

... pcpPGK4, was completely sequenced. It contained an open reading frame (ORF) of 3000 bp which encoded three consecutive PGK proteins (Fig. 2). As the cDNA clone was not complete at the 5¢-end, no transit peptide and only the C-terminal part of the first PGK segment were found. The two subsequent PGK p ...
Limits of adaptation to high dietary protein intakes
Limits of adaptation to high dietary protein intakes

... not suf®cient criterion. In addition there is the need to determine the extent to which the demand for a critical range of functions has been satis®ed. For the system as a whole the demand side is determined by the pattern and rate of protein synthesis and the utilisation of amino acids for other me ...
Bioinformatics of proteins: Sequence, structure and the `symbiosis
Bioinformatics of proteins: Sequence, structure and the `symbiosis

COMPUTATIONAL PERSPECTIVE IN THE STRUCTURAL STABILITY OF ‘ALL­ALPHA’  PROTEINS: THE N­H...Π INTERACTIONS 
COMPUTATIONAL PERSPECTIVE IN THE STRUCTURAL STABILITY OF ‘ALL­ALPHA’  PROTEINS: THE N­H...Π INTERACTIONS 

... have  carried  out  data  base  analysis  to  establish  the  stability  of  proteins. A  folded protein is stabilized by a number of  noncovalent  interactions such as hydrophobic interactions, hydrogen bonds,  salt  bridges,  and  cation‐aromatic  interactions  1,2.  In  addition,  there  has  bee ...
Full Text  - Journal of Pharmaceutical, Chemical and
Full Text - Journal of Pharmaceutical, Chemical and

... Ginkgo biloba leaves mainly contain these two physiological active ingredients: flavonoids and terpene lactones. Flavonoids have an important role in regulating plant growth and development. Anthocyanidin reductase is a key enzyme involved in the flavonoids biosynthesis. Based on the EST sequence, t ...
Understanding nature`s catalytic toolkit
Understanding nature`s catalytic toolkit

... by all of the other residues in the active site and the rest of the enzyme, and not only by the residues with which they interact directly. The functions of secondary residues The simplest of the functions performed by secondary interactions is orientation. Making bonds between residues restricts th ...
Protein quality of linseed for growing broiler chicks
Protein quality of linseed for growing broiler chicks

... for total amino acids for diets containing linseed to compared to SBM diet. The response of individual amino acids to inclusion level of linseed was linear (P<0.001). The TTTR values followed a similar trend than that found for apparent retention. In conclusion, utilization of linseed protein by bro ...
Repeat proteins challenge the concept of structural domains
Repeat proteins challenge the concept of structural domains

... correlate with biological activities and many modern proteins can be described as composed by novel ‘domain arrangements’ [2]. For globular proteins, this fact facilitates the description, evolution and construction of single amino acid chains that comprise a set of integrated biological functions, ...
Site-directed mutagenesis of key amino acids in the active site of
Site-directed mutagenesis of key amino acids in the active site of

... N, A, B, B’ and C (Fig. 1) (SKOV et al., 2001). Domains A, B and C are characteristic of family 13 whereas the two additional domains, N and B’, are unique. Domain A (residues 98–184, 261–395 and 461–550) is the characteristic (β/α)8 -barrel catalytic domain. In the α-amylase family, the conserved c ...
How Translocons Select Transmembrane Helices
How Translocons Select Transmembrane Helices

... found in all organisms that is directly responsible for inserting α-helical proteins into membranes TM: transmembrane MD: molecular dynamics ...
< 1 ... 17 18 19 20 21 22 23 24 25 ... 190 >

Ribosomally synthesized and post-translationally modified peptides

Ribosomally synthesized and post-translationally modified peptides (RiPPs), also known as ribosomal natural products, are a diverse class of natural products of ribosomal origin. Consisting of more than 20 sub-classes, RiPPs are produced by a variety of organisms, including prokaryotes, eukaryotes, and archaea, and they possess a wide range of biological functions.As a consequence of the falling cost of genome sequencing and the accompanying rise in available genomic data, scientific interest in RiPPs has increased in the last few decades. Because the chemical structures of RiPPs are more closely predictable from genomic data than are other natural products (e.g. alkaloids, terpenoids), their presence in sequenced organisms can, in theory, be identified rapidly. This makes RiPPs an attractive target of modern natural product discovery efforts.
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