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The enemy within: ricin and plant cells
The enemy within: ricin and plant cells

... plants whose ribosomes are sensitive to their endogenous RIPs, and is presumably a strategy to prevent these toxins from accidentally reaching the cytosol (Bonness et al., 1994). Most of these RIPs are, in fact, targeted into the ER lumen and sorted to the protein storage vacuoles, like ricin, or de ...
Study of Alternative Functions of the Mitochondrial Protein Bak
Study of Alternative Functions of the Mitochondrial Protein Bak

... The structures of non-activated Bak and Bax resemble that of other prosurvival proteins: globular structures composed of 9 α-helices. Within a bundle of 7 amphipathic (consisting of both hydrophobic and hydrophilic parts) helices resides the hydrophobic α5 helix. At the Cterminus, the remaining α9 a ...
Gonococcal outer-membrane protein PIB
Gonococcal outer-membrane protein PIB

... those from other serovars reveals that sequence variations occur in two discrete regions of the molecule centred on residues 1% (Varl) and 237 (Var2). A series of peptides spanning the amino acid sequence of the protein were synthesized on solid-phase supports and reacted with a panel of monoclonal ...
proposal-aug25
proposal-aug25

... hundreds of new consensus sequences that were not previously recognized as short linear motifs. Within these clusters, we have 30 unknown consensus sequences with 20 or more conserved examples in the yeast proteome. Although many of the novel consensus sequences identified by the cluster analysis mi ...
Protein quality of linseed for growing broiler chicks
Protein quality of linseed for growing broiler chicks

Towards the storage metabolome: profiling the barley vacuole
Towards the storage metabolome: profiling the barley vacuole

... are found in locations other than those they were thought to operate for example hexokinase proteins have been found in the nucleus whilst the sucrose synthase has been localized to the mitochondria (Subbaiah et al., 2006; Cho et al., 2007). These observations thus render such predictions of metabol ...
Analyzing Effects of Naturally Occurring Missense Mutations
Analyzing Effects of Naturally Occurring Missense Mutations

The role of multifunctional M1 metallopeptidases
The role of multifunctional M1 metallopeptidases

... † Background Metallopeptidases of the M1 family are found in all phyla (except viruses) and are important in the cell cycle and normal growth and development. M1s often have spatiotemporal expression patterns which allow for strict regulation of activity. Mutations in the genes encoding M1s result i ...
PROTEIN METABOLISM
PROTEIN METABOLISM

... the general nature of the genetic code came from many types of experiments, including genetic experiments on the effects of deletion and insertion mutations. Inserting or deleting one base pair (shown here in the mRNA transcript) alters the sequence of triplets in a nonoverlapping code; all amino ac ...
MICROSTRUCTURE OF PROTEIN BODIES IN MARAMA BEAN SPECIES
MICROSTRUCTURE OF PROTEIN BODIES IN MARAMA BEAN SPECIES

... of spherical globoids from many legumes showed that they are rich sources of P, K, Ca and Mg (Lott and Buttrose, 1978; Lott, 1981). These minerals were found in high concentration in marama beans (Table 3), probably originated mainly from the globoid sites. Most soya protein bodies did not contain g ...
Translocation of proteins across the cell envelope of Gram
Translocation of proteins across the cell envelope of Gram

... Translocation takes place through a con¢ned aqueous channel composed of a set of integral membrane proteins [24,25]. The general architecture of this channel is conserved among bacteria, archaea and eukaryotes [26]. In addition, the channel proteins provide a binding site for cytoplasmic components ...
Journal of Agricultural and Food Chemistry
Journal of Agricultural and Food Chemistry

... Gorinstein et al., 1996). There also are investigations showing comparisons among soybean, oats, and amaranth in relation to nutritional, structural, and functional properties (Gorinstein, 1993; Marcone and Yada, 1992; Segura-Nieto et al., 1994). To date, there is no information on the relative stab ...
Article Lateral Gene Transfer and Gene
Article Lateral Gene Transfer and Gene

... is compartmentalized within these organelles, and ATP is generated via ASCT and SCS; however, in organisms that contain mitosomes, pyruvate-metabolizing enzymes and hydrogenase operate in the cytosol, and the cytosolic activity of ACS generates ATP (M€uller et al. 2012). Hydrogenosomes have been fou ...
Transcript - UAB School of Optometry
Transcript - UAB School of Optometry

... a. Amino acids form Schiff bases which play a very important role in biology, and side chains have unique reactions. XIV. SPECTROSCOPIC PROPERTIES [S44] a. Aromatic amino acids absorb UV light at a maximum around 280 nm. i. Can use this to detect proteins, so when purifying proteins or when looking ...
Full Text  - Journal of Pharmaceutical, Chemical and
Full Text - Journal of Pharmaceutical, Chemical and

... has not been published in the literature. In the present study, an ANR gene was isolated from G. biloba leaves by PCR method. Sequence analysis indicated that the cDNA of GbANR was 1597 bp containing a 1023 bp open reading frame (ORF) encoding 340 amino acids. Homology analysis showed that the deduc ...
Protein sorting at the ER–Golgi interface
Protein sorting at the ER–Golgi interface

... to transmembrane domains in the ER and concentrates them to ERES from where they are efficiently transported to the Golgi via COP​II vesicles. Rer1 and Erv14 bind their clients in a regulated manner, capturing cargoes in one compartment and releasing them in another before they return to their origi ...
The TACC proteins: TACC-ling microtubule dynamics and
The TACC proteins: TACC-ling microtubule dynamics and

NSPKU
NSPKU

... baby will be given a special Phe-free formula until the levels of Phe fall back to normal levels (usually within a few days). Step 2: Once the levels of Phe are under control a small restricted amount of breastmilk will be given along with the Phe free formula to provide the limited Phe essential fo ...
The Golgi-Localized Arabidopsis Endomembrane
The Golgi-Localized Arabidopsis Endomembrane

... signal of EMP12 trapped several post-Golgi membrane proteins within the Golgi apparatus in a gain-of-function analysis using transiently expressed Arabidopsis protoplasts. It seems that these targeting features of EMP12 are conserved among the plant EMPs for their correct targeting to the Golgi appa ...
Archaea
Archaea

...  Chemoorganotrophy and chemolithotrophy ▪ With the exception of methanogenesis, bioenergetics and intermediary metabolism of Archaea are similar to those found in Bacteria - Glucose metabolism : EMP or slightly modified Entner-Doudoroff pathway ...
GPCR–G fusion proteins
GPCR–G fusion proteins

... non-fused A1 receptor co-expressed with the different Gi/Go-proteins16. Unexpectedly, marked differences have been observed for the coupling of the b2AR to GsaS and GsaL. Specifically, the b2AR fused to GsaL shows the properties of constitutive activity, whereas the b2AR fused to GsaS does not1,4,5. ...
Autophagy in Plasmodium, a multifunctional pathway?
Autophagy in Plasmodium, a multifunctional pathway?

... while Atg13 appears absent. The C-terminal Atg13-binding domain is also missing from PfAtg1. It contains several potential Atg8interacting motifs, which mediate Atg1 binding to Atg8 in an Atg13independent manner in yeast and humans [32]. PfVps34 exists in P. falciparum and is one of the better-chara ...
Hamster Placental Lactogen-ll Contains a Structural Feature Unique
Hamster Placental Lactogen-ll Contains a Structural Feature Unique

... 900 bp which was also sequenced. The composite nucleotide sequence for the three cDNAs is shown in Fig. 1. The overlapping portions of the cDNAs differed only in the starting point for the poly(A) tail; it follows nucleotide 850 for two of the cDNAs and nucleotide 857 for the third. The composite se ...
Proteomic Analysis of the Arabidopsis Nucleolus Suggests Novel
Proteomic Analysis of the Arabidopsis Nucleolus Suggests Novel

... involved in DNA replication and gene expression (Lamond and Earnshaw, 1998). The most prominent nuclear subcompartment is the nucleolus, which is the site of transcription and processing of ribosomal RNAs (rRNAs), and their assembly into ribosomal subunits before export to the cytoplasm (Olsen et al ...
The significance of biochemical and molecular sample integrity in
The significance of biochemical and molecular sample integrity in

... were obtained from the Stanley Foundation Brain Bank [12]. In a first experiment 16 mice were randomly divided into four groups (Table 1). The first group was sacrificed by focused microwave irradiation (Muromachi Kikai, Tokyo, Japan), 1.4 s at 4.5–5 kW (control group). Three groups of animals were ...
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Magnesium transporter

This page links directly from the magnesium in biological systems page.Magnesium transporters are proteins that transport magnesium across the cell membrane. All forms of life require magnesium, yet the molecular mechanisms of Mg2+ uptake from the environment and the distribution of this vital element within the organism are only slowly being elucidated.In bacteria, Mg2+ is probably mainly supplied by the CorA protein and, where the CorA protein is absent, by the MgtE protein. In yeast the initial uptake is via the Alr1p and Alr2p proteins, but at this stage the only internal Mg2+ distributing protein identified is Mrs2p. Within the protozoa only one Mg2+ transporter (XntAp) has been identified. In metazoa, Mrs2p and MgtE homologues have been identified, along with two novel Mg2+ transport systems TRPM6/TRPM7 and PCLN-1. Finally, in plants, a family of Mrs2p homologues has been identified along with another novel protein, AtMHX.
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