File produced at level 10
... We do not yet know exactly how phospholipid bilayers are deformed during this process to allow membrane topology rearrangement. Curiously, researchers who made yeast strains with fluorescently tagged Dnm1 found that not all the protein in the cell associates with mitochondria (Otsuga et al. 1998; Se ...
... We do not yet know exactly how phospholipid bilayers are deformed during this process to allow membrane topology rearrangement. Curiously, researchers who made yeast strains with fluorescently tagged Dnm1 found that not all the protein in the cell associates with mitochondria (Otsuga et al. 1998; Se ...
CELLULAR ADAPTATION TO AMINO ACID AVAILABILITY:
... D. Ron’s group has identified a signalling pathway for regulating gene expression in mammals that is homologous to the wellcharacterised yeast general control response to amino acid deprivation (Harding et al. 2000). Its components include (figure 3) the mammalian homologue of the GCN2 kinase, the i ...
... D. Ron’s group has identified a signalling pathway for regulating gene expression in mammals that is homologous to the wellcharacterised yeast general control response to amino acid deprivation (Harding et al. 2000). Its components include (figure 3) the mammalian homologue of the GCN2 kinase, the i ...
Intestinal peptidases form functional complexes with the neutral
... Protein complexes containing APN and other brush-border peptide hydrolases have been isolated from intestinal brush-border membranes using Blue native electrophoresis [19], but these did not seem to contain membrane transporters. There is also evidence of a role for intestinal microvillar micro-doma ...
... Protein complexes containing APN and other brush-border peptide hydrolases have been isolated from intestinal brush-border membranes using Blue native electrophoresis [19], but these did not seem to contain membrane transporters. There is also evidence of a role for intestinal microvillar micro-doma ...
The Effects of Whey Protein and Leucine Supplementation
... of the resistance training program (8,9). For example, recent studies have shown that an increase in the volume of resistance training from one set to two or more sets results in the recruitment of additional motor units and, therefore, greater neuromuscular adaptations, strength gains, and hypertro ...
... of the resistance training program (8,9). For example, recent studies have shown that an increase in the volume of resistance training from one set to two or more sets results in the recruitment of additional motor units and, therefore, greater neuromuscular adaptations, strength gains, and hypertro ...
Succinate Dehydrogenase of Saccharomyces cerevisiae
... The catalytic activity of succinate dehydrogenase is modulated both by post translational phosphorylation/acetylation and active site inhibition. For example, phosphorylation of the Sdh1 subunit leads to attenuate activity of SDH. The activity of this enzyme may be also modulated by Krebs cycle inte ...
... The catalytic activity of succinate dehydrogenase is modulated both by post translational phosphorylation/acetylation and active site inhibition. For example, phosphorylation of the Sdh1 subunit leads to attenuate activity of SDH. The activity of this enzyme may be also modulated by Krebs cycle inte ...
Comparative genomic analysis of carbon and nitrogen assimilation
... are indicated at the top of each panel and amplification product sizes are indicated at the bottom of each panel. ...
... are indicated at the top of each panel and amplification product sizes are indicated at the bottom of each panel. ...
The Tobacco Mosaic Virus 126-Kilodalton Protein
... represent 5# and 3# untranslated regions, rectangular boxes represent open reading frames, and arrowed rectangles represent promoter sequences. Promoter-gene-terminator constructs for particle bombardment (D) or agroinfiltration (A, B, C, D) studies and TMV constructs for virus infection studies (E ...
... represent 5# and 3# untranslated regions, rectangular boxes represent open reading frames, and arrowed rectangles represent promoter sequences. Promoter-gene-terminator constructs for particle bombardment (D) or agroinfiltration (A, B, C, D) studies and TMV constructs for virus infection studies (E ...
2.3.3 Protein and amino acid metabolism
... universal fuels, for other tissues. This enables the liver to accommodate dietary amino acid disposal within the bounds of its oxygen consumption. In an adult in nitrogen balance, the daily dietary amino acid intake must be oxidized in a 24-h period. If the liver were too efficient in the clearance ...
... universal fuels, for other tissues. This enables the liver to accommodate dietary amino acid disposal within the bounds of its oxygen consumption. In an adult in nitrogen balance, the daily dietary amino acid intake must be oxidized in a 24-h period. If the liver were too efficient in the clearance ...
A Directed Mutagenesis Screen in Drosophila
... normally functions to inhibit Hh signaling. This becomes obvious as the ptc loss-of-function phenotype in Drosophila embryos is identical to the phenotype caused by overexpression of hh (Ingham 1993). In fact, ptc encodes the only protein yet known to bind the Hh protein directly (Stone et al. 1996) ...
... normally functions to inhibit Hh signaling. This becomes obvious as the ptc loss-of-function phenotype in Drosophila embryos is identical to the phenotype caused by overexpression of hh (Ingham 1993). In fact, ptc encodes the only protein yet known to bind the Hh protein directly (Stone et al. 1996) ...
Mistranslation and its control by tRNA synthetases
... oligonucleotide substrates that contain only a few base pairs from the end of the acceptor arm are robust substrates, provided they encode G:U [41]. Because the G:U base pair is distinct from and distal to the anticodon triplet of the code, the relationship between alanine and the nucleotide triplet ...
... oligonucleotide substrates that contain only a few base pairs from the end of the acceptor arm are robust substrates, provided they encode G:U [41]. Because the G:U base pair is distinct from and distal to the anticodon triplet of the code, the relationship between alanine and the nucleotide triplet ...
Translocation of Globin Fusion Proteins across the Endoplasmic
... demonstrated that normally cytosolic proteins can be redirected to the endoplasmic reticulum lumen by a signal sequence, that translocation can be uncoupled from translation, and that amino-terminal signal sequences have the intrinsic ability to direct translocation of both amino and carboxyl flanki ...
... demonstrated that normally cytosolic proteins can be redirected to the endoplasmic reticulum lumen by a signal sequence, that translocation can be uncoupled from translation, and that amino-terminal signal sequences have the intrinsic ability to direct translocation of both amino and carboxyl flanki ...
... Choice A: Briefly describe the molecular basis of the hydrophobic effect and indicate its role in the stability of folded proteins. Choice B: Briefly describe conformational entropy and indicate its role in the stability of folded proteins. Choice C: Briefly describe the role of van der Waals forces ...
Mucolipin 1 channel activity is regulated by protein kinase A
... activity. The stimulatory effect of H89 on MCOLN1 function was not observed when Ser557 and Ser559 were mutated to alanine residues, indicating that these two residues are essential for PKAmediated negative regulation of MCOLN1. This paper presents the first example of regulation of a member of the ...
... activity. The stimulatory effect of H89 on MCOLN1 function was not observed when Ser557 and Ser559 were mutated to alanine residues, indicating that these two residues are essential for PKAmediated negative regulation of MCOLN1. This paper presents the first example of regulation of a member of the ...
Modeling Root Zone Effects on Preferred Pathways for the Passive
... Figure 1). In addition, the model root is further discretized along the longitudinal axis with the height of each compartment reflecting the height of an individual cell. Hence, the height of each compartment varies across the EZ (see Figure 1B). For simplicity we assume axial symmetry. Therefore, t ...
... Figure 1). In addition, the model root is further discretized along the longitudinal axis with the height of each compartment reflecting the height of an individual cell. Hence, the height of each compartment varies across the EZ (see Figure 1B). For simplicity we assume axial symmetry. Therefore, t ...
Photoreceptor Membrane Proteins, Phototransduction, and Retinal
... Although ultrastructural features of ROS had been described in considerable detail by the early 1970s, relatively few studies dealt directly with the molecular composition of this lightsensitive organelle. This was due largely to the lack of a pure, well-characterized ROS preparation and to technica ...
... Although ultrastructural features of ROS had been described in considerable detail by the early 1970s, relatively few studies dealt directly with the molecular composition of this lightsensitive organelle. This was due largely to the lack of a pure, well-characterized ROS preparation and to technica ...
Nutrition to Support Recovery from Endurance Exercise: Optimal
... Carbohydrate intake is crucial to enhance muscle and liver glycogen stores after high-intensity, carbohydratebased exercise. The rate of muscle glycogen resynthesis is generally greatest during the initial È1 h after exercise and is facilitated by the contraction-induced recruitment of GLUT-4 transp ...
... Carbohydrate intake is crucial to enhance muscle and liver glycogen stores after high-intensity, carbohydratebased exercise. The rate of muscle glycogen resynthesis is generally greatest during the initial È1 h after exercise and is facilitated by the contraction-induced recruitment of GLUT-4 transp ...
Plasma membrane repair in plants
... or proof for membrane repair mechanisms have been discovered in plants. However, Arabidopsis SYT1 is now the first plant synaptotagmin demonstrated to participate in Ca2+-dependent repair of membranes. This suggests a conservation of membrane repair mechanisms between animal and plant cells. Plasma ...
... or proof for membrane repair mechanisms have been discovered in plants. However, Arabidopsis SYT1 is now the first plant synaptotagmin demonstrated to participate in Ca2+-dependent repair of membranes. This suggests a conservation of membrane repair mechanisms between animal and plant cells. Plasma ...
Catalytic and transport cycles of ABC exporters
... observed [13,14]. Thus the TMDs of importers and exporters cannot be easily interchanged in models of transport. It is best to consider the coupling mechanisms of these proteins in three distinct groups on the basis of their structures [15,16]. (i) ABC export‑ ers, which are found in all kingdoms of ...
... observed [13,14]. Thus the TMDs of importers and exporters cannot be easily interchanged in models of transport. It is best to consider the coupling mechanisms of these proteins in three distinct groups on the basis of their structures [15,16]. (i) ABC export‑ ers, which are found in all kingdoms of ...
Posttranslational Protein Modiications in Plant
... regulation of plant metabolism by PTMs, in particular for enzymes in primary metabolism (Calvin cycle, glycolysis, and respiration) and the C4 shuttle accommodating photosynthesis in C4 plants (Table III). As will be evident, most of these classic examples involve regulation by (de)phosphorylation, ...
... regulation of plant metabolism by PTMs, in particular for enzymes in primary metabolism (Calvin cycle, glycolysis, and respiration) and the C4 shuttle accommodating photosynthesis in C4 plants (Table III). As will be evident, most of these classic examples involve regulation by (de)phosphorylation, ...
CHEMICAL SYNTHESIS OF PROTEINS : A TOOL FOR PROTEIN
... functional features of the proteins refers to the modification of their chemical structure. In this regard, the chemical synthesis of proteins appears a key tool, as it allows the unlimited modification of a polypeptide chain with any kind and number of labels. The last decade has seen the introduct ...
... functional features of the proteins refers to the modification of their chemical structure. In this regard, the chemical synthesis of proteins appears a key tool, as it allows the unlimited modification of a polypeptide chain with any kind and number of labels. The last decade has seen the introduct ...
Lo, Frederick: Three Recently Developed Algorithms for Aligning Distantly Related Proteins
... situation that can often occur for distantly related proteins. Jaroszewski, Li, and Godzik present two general methods for generating sets of suboptimal alignments, then demonstrate that a hybrid of the general methods returns better sets of suboptimal alignments. The immediately apparent problem is ...
... situation that can often occur for distantly related proteins. Jaroszewski, Li, and Godzik present two general methods for generating sets of suboptimal alignments, then demonstrate that a hybrid of the general methods returns better sets of suboptimal alignments. The immediately apparent problem is ...
