Endoplasmic reticulum–mitochondria contacts: function of the junction
... microtubules by factors that associate with the microtubule motor kinesin 1. In the case of mitochondria, this occurs through kinesin 1 binding to the cytoplasmic protein MILTON, which in turn binds MIRO on the outer mitochondrial membrane. MIRO is important for mitochondrial movement. Less is known ...
... microtubules by factors that associate with the microtubule motor kinesin 1. In the case of mitochondria, this occurs through kinesin 1 binding to the cytoplasmic protein MILTON, which in turn binds MIRO on the outer mitochondrial membrane. MIRO is important for mitochondrial movement. Less is known ...
PDF - Oxford Academic - Oxford University Press
... SDPpred does not require information about the 3D protein structure, which instead can be used at the post-processing step to validate the predictions. There are also other approaches for comparative analysis of protein subfamilies. One of these methods, called DIVERGE (17) takes into account the di ...
... SDPpred does not require information about the 3D protein structure, which instead can be used at the post-processing step to validate the predictions. There are also other approaches for comparative analysis of protein subfamilies. One of these methods, called DIVERGE (17) takes into account the di ...
Structural Mechanisms for Regulation of Membrane
... illustrate the remarkable degree to which Rab GEFs have evolved not only to recognize different Rab substrates but also to facilitate nucleotide exchange through largely unrelated structural mechanisms. The 17 kDa protein Mss4 and its yeast ortholog Dss4 were among the first Rab GEFs identified (62, ...
... illustrate the remarkable degree to which Rab GEFs have evolved not only to recognize different Rab substrates but also to facilitate nucleotide exchange through largely unrelated structural mechanisms. The 17 kDa protein Mss4 and its yeast ortholog Dss4 were among the first Rab GEFs identified (62, ...
Filip Jagodzinski - WWU Computer Science Faculty Web Pages
... Computer Architecture (CS312), Software Engineering Mobile Apps (CS498), Modeling (CS298). ...
... Computer Architecture (CS312), Software Engineering Mobile Apps (CS498), Modeling (CS298). ...
Biochemical and physiological bases for utilization
... day of birth until seven days of age, and suggested that the endogenous synthesis of arginine is important for the animal’s optimal growth and development particularly ...
... day of birth until seven days of age, and suggested that the endogenous synthesis of arginine is important for the animal’s optimal growth and development particularly ...
Provitamin A Accumulation in Cassava (Manihot
... PCR-amplified PSY region. The presence of Asp at position 191, replacing the conserved Ala, was decisive for carotenoid accumulation (see Supplemental Table 2 online). ...
... PCR-amplified PSY region. The presence of Asp at position 191, replacing the conserved Ala, was decisive for carotenoid accumulation (see Supplemental Table 2 online). ...
Interaction of the endothelial nitric oxide synthase with the CAT
... or not a single CAT-1 intracellular domain is sufficient to mediate the interaction. eNOS–CAT-1 association has been proposed as an explanation for the ‘arginine paradox’ [5]. The arginine paradox arises from the observation that, while the K m of eNOS for arginine is in the range 3–5 µM [7,8], the ...
... or not a single CAT-1 intracellular domain is sufficient to mediate the interaction. eNOS–CAT-1 association has been proposed as an explanation for the ‘arginine paradox’ [5]. The arginine paradox arises from the observation that, while the K m of eNOS for arginine is in the range 3–5 µM [7,8], the ...
Benzoate mediates the simultaneous repression of anaerobic 4
... cells were used as inoculum (data not shown). A notable observation is the unaltered utilization hierarchy with the ternary mixture, i.e. benzoate over succinate and 4methylbenzoate, mirroring the preferences observed with respective binary mixtures (Figure 1a–c). Transcript and protein dynamics (te ...
... cells were used as inoculum (data not shown). A notable observation is the unaltered utilization hierarchy with the ternary mixture, i.e. benzoate over succinate and 4methylbenzoate, mirroring the preferences observed with respective binary mixtures (Figure 1a–c). Transcript and protein dynamics (te ...
integumentary amino acid transport and metabolism in the apodous
... steady-state concentration of ["CJglycine in the animals was three times that of the incubation medium suggesting the presence of a transport mechanism capable of transferring the amino acid against a concentration gradient. During exposure to 1 /IM ["CJglycine in artificial seawater medium, for per ...
... steady-state concentration of ["CJglycine in the animals was three times that of the incubation medium suggesting the presence of a transport mechanism capable of transferring the amino acid against a concentration gradient. During exposure to 1 /IM ["CJglycine in artificial seawater medium, for per ...
Introduction - ART
... functions in eukaryotes through its covalent conjugation to other intracellular proteins. Substrates marked with a polymer of ubiquitins (a polyubiquitin chain) are selectively targeted to a multisubunit ATP-dependent protease known as the 26 proteasome (Hershko et al., 1998), whereas certain substr ...
... functions in eukaryotes through its covalent conjugation to other intracellular proteins. Substrates marked with a polymer of ubiquitins (a polyubiquitin chain) are selectively targeted to a multisubunit ATP-dependent protease known as the 26 proteasome (Hershko et al., 1998), whereas certain substr ...
Structural studies on lysosomal proteins
... the protein structure in a way that cannot be compensated by other amino acids. Enzyme enhancement therapy with chemical chaperones is a novel treatment for LSDs and has shown potential also for Pompe disease. In this study, the stabilisation capacity of potential chemical chaperones for GAA were te ...
... the protein structure in a way that cannot be compensated by other amino acids. Enzyme enhancement therapy with chemical chaperones is a novel treatment for LSDs and has shown potential also for Pompe disease. In this study, the stabilisation capacity of potential chemical chaperones for GAA were te ...
Diagnosis and Rectification of Arrested Fermentations
... intolerance. Causes of Fermentation Arrest The process of fermentation has been extensively studied in the yeast Saccharomyces. There are many known causes of arrest of fermentation. The role of these factors in arrest has been confirmed in laboratory studies and in bench scale grape juice fermentat ...
... intolerance. Causes of Fermentation Arrest The process of fermentation has been extensively studied in the yeast Saccharomyces. There are many known causes of arrest of fermentation. The role of these factors in arrest has been confirmed in laboratory studies and in bench scale grape juice fermentat ...
Characterization of the Cytosolic Proteins Involved in the Amoeboid
... The amoeboid sperm of Ascaris crawl through a cycle of protrusion, adhesion, and retraction, similar to that seen in conventional actin-based cells. However, instead of actin, these cells power their movement through modulation of the major sperm protein (MSP) cytoskeleton. MSP forms dense filament ...
... The amoeboid sperm of Ascaris crawl through a cycle of protrusion, adhesion, and retraction, similar to that seen in conventional actin-based cells. However, instead of actin, these cells power their movement through modulation of the major sperm protein (MSP) cytoskeleton. MSP forms dense filament ...
nitrogen assimilation and global regulation in escherichia coli
... occurs is not stated. A hybrid hypothesis is that glutamine accumulation prevents Ntr gene expression until glutamate starvation stops metabolism and growth. In any case, the arguments are complex and subject to several untested assumptions (35). It is possible that the explanation for the Asm− phen ...
... occurs is not stated. A hybrid hypothesis is that glutamine accumulation prevents Ntr gene expression until glutamate starvation stops metabolism and growth. In any case, the arguments are complex and subject to several untested assumptions (35). It is possible that the explanation for the Asm− phen ...
Protein Similarity Score - Santa Clara Law Digital Commons
... are, the more likely it is that they will be functional equivalents. However, in many cases substantial variations between sequences are tolerated without giving rise to any substantial difference in threedimensional conformation or function.1 2 In naturally-occurring proteins, for instance, sequenc ...
... are, the more likely it is that they will be functional equivalents. However, in many cases substantial variations between sequences are tolerated without giving rise to any substantial difference in threedimensional conformation or function.1 2 In naturally-occurring proteins, for instance, sequenc ...
Metabolic flux profiling of recombinant protein secreting Pichia
... Growth and product formation of recombinant P. pastoris strains There are only few physiological studies on the potential impact of recombinant protein production on the core metabolism of P. pastoris, particularly for those cases where the product is secreted [9, 15]. The aim of our study was to q ...
... Growth and product formation of recombinant P. pastoris strains There are only few physiological studies on the potential impact of recombinant protein production on the core metabolism of P. pastoris, particularly for those cases where the product is secreted [9, 15]. The aim of our study was to q ...
Identification of proteins localized to the contractile vacuole of
... The spongiome is a fluid storing compartment in Paramecium (Allen 2000) and function as collecting ducts to accumulate excess water in Dictyostelium (Du et al. 2008). The second compartment of the contractile vacuole, the bladder, expands as a reservoir for water storage (Rohloff and Docampo 2008) a ...
... The spongiome is a fluid storing compartment in Paramecium (Allen 2000) and function as collecting ducts to accumulate excess water in Dictyostelium (Du et al. 2008). The second compartment of the contractile vacuole, the bladder, expands as a reservoir for water storage (Rohloff and Docampo 2008) a ...
dravhandling-hafte - DUO
... destinations. In this pathway, proteins travel from the endoplasmic reticulum (ER) through the Golgi apparatus to the plasma membrane, or to endosomes and lysosomes. The transport of proteins between membrane compartments of the secretory pathway takes place in a sequential manner involving both coa ...
... destinations. In this pathway, proteins travel from the endoplasmic reticulum (ER) through the Golgi apparatus to the plasma membrane, or to endosomes and lysosomes. The transport of proteins between membrane compartments of the secretory pathway takes place in a sequential manner involving both coa ...
![Basic region of residues 228-231 of protein kinase CK1[alpha] is](http://s1.studyres.com/store/data/015745345_1-81da768c37e720623b4b1898472e2f2e-300x300.png)
Basic region of residues 228-231 of protein kinase CK1[alpha] is
... in these assays was produced by 35S labeling through an in vitro transcription-translation system or by allowing CK1a to autophosphorylate with 32P. Alternatively, the presence of active CK1a bound to axin on the sepharose beads can be assayed by determining its capacity to phosphorylate a specific ...
... in these assays was produced by 35S labeling through an in vitro transcription-translation system or by allowing CK1a to autophosphorylate with 32P. Alternatively, the presence of active CK1a bound to axin on the sepharose beads can be assayed by determining its capacity to phosphorylate a specific ...
The evolution of silicon transporters in diatoms
... average coverage across the predicted exons. If coverage did not decrease across an open reading frame with a predicted intron, it was considered part of the open reading frame. Gene models were extended to the first in-frame methionine and the last in-frame stop codon within the transcribed region ...
... average coverage across the predicted exons. If coverage did not decrease across an open reading frame with a predicted intron, it was considered part of the open reading frame. Gene models were extended to the first in-frame methionine and the last in-frame stop codon within the transcribed region ...
Modulation of the Antigenic Peptide Transporter TAP by
... C-terminal truncations of the identified peptide were probed with hybridoma supernatant (Figure 2). A linear epitope was identified corresponding to the very last five C-terminal amino acid residues of TAP1 ( 744 ADAPE 748 ) (Figure 2(b) and (c)). Here, the binding efficiency was fully preserved whe ...
... C-terminal truncations of the identified peptide were probed with hybridoma supernatant (Figure 2). A linear epitope was identified corresponding to the very last five C-terminal amino acid residues of TAP1 ( 744 ADAPE 748 ) (Figure 2(b) and (c)). Here, the binding efficiency was fully preserved whe ...
The Activity of a Developmentally Regulated Cysteine Proteinase Is
... release and extracellular organization. Nevertheless, little is known about the molecular events related to cyst wall biogenesis in Giardia. Among the components of the cyst wall there are two proteins that we have previously identified and characterized: CWP1 (26 kDa) and CWP2 (39 kDa). Expression ...
... release and extracellular organization. Nevertheless, little is known about the molecular events related to cyst wall biogenesis in Giardia. Among the components of the cyst wall there are two proteins that we have previously identified and characterized: CWP1 (26 kDa) and CWP2 (39 kDa). Expression ...
A cellular backline: specialization of host membranes for defence
... and location of callose synthesis in response to pathogen penetration. Another scenario which has implicated membrane composition in callose deposition is the production of lipase by the pathogen Fusarium graminarum. Production of the lipase reduces callose deposition during pathogen infection of sp ...
... and location of callose synthesis in response to pathogen penetration. Another scenario which has implicated membrane composition in callose deposition is the production of lipase by the pathogen Fusarium graminarum. Production of the lipase reduces callose deposition during pathogen infection of sp ...