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news and views Mechanics of the ribosome
news and views Mechanics of the ribosome

... on a surer footing, and promise much more. At this resolution, a-helices (spirals) in the protein structures can be readily fitted to the electron-density maps of the subunits, as can most double-helical segments (around twothirds) of the rRNA’s structure. Moreover, known three-dimensional structure ...
Yeast a Mighty Tiny Fungus
Yeast a Mighty Tiny Fungus

... bacteria. Like plants and animals, fungi are eukaryotic organisms, meaning that their cells contain a nucleus and membrane-bound organelles such as mitochondria. Fungi have some features similar to plants: They don’t move around and their cells have cell walls. Like animals, fungi have no chlorophyl ...
Higher Expression Level and Lower Toxicity of Genetically Spliced
Higher Expression Level and Lower Toxicity of Genetically Spliced

... a phospholipase C (PLC) mediated pathway (9). Therefore, it can be suggested that removing amino acids 114-135 could effectively lower, if not inhibit, the toxicity of NSP4 for two reasons: first, via disrupting the correct functional conformation and oligomerization of the protein and second, via b ...
C2006/F2402 `07
C2006/F2402 `07

... A-1. Inhibition of Nedd4 could be used for: (up regulation of Na+ transport) (down regulation of Na+ transport) (both) (neither). A-2. Endocytosis of ENaC is probably triggered by (binding of ENaC to its receptor) (binding of ENaC to its ligand) (covalent modification of ENaC) (binding of ENaC to it ...
Vp-1  Neurospora crassa circadian clock in chemostat culture
Vp-1 Neurospora crassa circadian clock in chemostat culture

... transmitters of the pheromone signal during mating partner recognition in filamentous fungi and yeasts. U. maydis encodes four G-alpha-subunits (gpa1−4). Since the only G-alpha-subunit knockout (gpa3) which is defective in cell fusion can be “reverted“ by cAMP supplementation, we hypothesized that t ...
Supplementary materials
Supplementary materials

... derived cladogram (i.e., figure 3) reflected the degree of similarity among organisms in expressed orthologous proteins under the conditions tested. Scoring the proteins according to an alternative scheme that reflected the fact that the more peptides per protein detected the more certain it is that ...
Schizosaccharomyces pombe Git1 Is a C2
Schizosaccharomyces pombe Git1 Is a C2

... somehow otherwise required for Gpa2-mediated activation of adenylate cyclase. In this study, we describe the cloning and characterization of the git11 gene. Surprisingly, while the other proteins of the S. pombe glucose/cAMP pathway have obvious homologs in other eukaryotes, Git1 is only distantly r ...
Genetic Research Produces a More Nutritious
Genetic Research Produces a More Nutritious

... nology, Dr. Marceline Egnin has developed a Earth, is a good candidate for space travel because it transgenic sweet potato that has dramatically enhas high levels of carbohydrates and minerals and hanced levels of protein and essential amino acids. therefore is a good source of energy. Also, the lea ...
Powerpoint
Powerpoint

... • Have the emergent properties of an organism as judged by its protein content been influenced by the environment? • Will do this by consideration of the metallomes of a broad range of species • The metallomes can only be deduced by consideration of the protein structures to which the metal is coval ...
N - KIAS
N - KIAS

... Volume 43, Issue 4, pages 465-475, 17 APR 2001 DOI: 10.1002/prot.1058 http://onlinelibrary.wiley.com/doi/10.1002/prot.1058/full#fig5 ...
DNA to Protein Overview
DNA to Protein Overview

... mentioned, bioMEMS are used in the biomedical field for analyzing specific biomolecules in a sample (e.g., the home pregnancy test and insulin monitoring) and for delivering minute amount of drugs (e.g., insulin delivery). In addition, MEMS technology and nanotechnology are used to develop the biome ...
Membrane Structure and Function
Membrane Structure and Function

... ion pumps?_____________________________________ transporters?____________________________________ Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings ...
bimat.org
bimat.org

... within the mineralized composite during formation of the molluscan shell and pearl. We have cloned and characterized the cDNA coding for Lustrin A, a newly described matrix protein from the nacreous layer of the shell and pearl produced by the abalone, Haliotis rufescens, a marine gastropod mollusc. ...
File
File

... • Asymmetric carbons bond to four different groups. • Molecules with asymmetric carbons can exist in two mirror-image configurations called enantiomers or stereoisomers. • Enantiomers can be as either D- or L-isomers. • Sugars can have many asymmetric carbons, but are designated D- or L- according t ...
search_2009
search_2009

... • The first round of PSI-BLAST is a standard protein-protein BLAST search. The program builds a position-specific scoring matrix (PSSM or profile) from an alignment of the sequences returned with Expect values better (lower) than the inclusion threshold (default=0.005). • The PSSM will be used to ev ...
Foldrec_2010 - Center for Biological Sequence Analysis
Foldrec_2010 - Center for Biological Sequence Analysis

... 160 GHPRAHFLDADPGFVHSDGTISH--HDMYDYLHLSRLGY ...
Identification of the tRNA-binding Protein Arc1p as a Novel Target of
Identification of the tRNA-binding Protein Arc1p as a Novel Target of

... blots and is not identical to one of the known biotinylated yeast proteins. After affinity purification on monomeric avidin, the biotinylated protein was identified as Arc1p. Using 14C-labeled biotin, the cofactor was shown to be incorporated into Arc1p by covalent and alkalistable linkage. Similar ...
Fact Sheet
Fact Sheet

... natural protein-containing foods are allowed in the diet. For infants, breast milk or regular infant formula is given in precise amounts. As the baby grows and can eat solid foods, the breast milk or regular infant formula will be removed from the diet and the propiogenic amino acids will come from ...
The monocarboxylate transporter family
The monocarboxylate transporter family

... in carbohydrate, fat, and amino acid metabolism and must be rapidly transported across the plasma membrane of cells (1, 2). Transport is mediated by proton-linked monocarboxylate transporters (MCTs), four of which (MCTs1–4) have been characterized in detail and will be the major focus of this review ...
The Genome of Methanosarcina mazei
The Genome of Methanosarcina mazei

... Methanobacterium thermoautotrophicum strain ∆H) (39 genes) (Smith et al., 1997). This difference is attributed to greater than three tRNAs for ten amino acids in M. mazei. Recently, it was described that TAG is an in-frame codon in the monomethylamine methyltransferase of M. barkeri (Paul et al., 20 ...
Disruption of CEP290 microtubule/membrane-binding domains
Disruption of CEP290 microtubule/membrane-binding domains

The plastid division proteins, FtsZ1 and FtsZ2, differ in their
The plastid division proteins, FtsZ1 and FtsZ2, differ in their

... with the presence of long filaments (Figure 1E). In contrast, FtsZ1 overexpression did not affect the growth rate during the first 2 h after induction. A decrease in growth rate was only observed after 3 h of protein induction, with the formation of multinucleate cells (Figure 1D), similar to cells ...
A simple calculus for proteins and cells
A simple calculus for proteins and cells

... µ −→ should have been larger than that of Definition 2 because of the presence of membranes. The transition relation preserve well-formedness of solutions. µ ...
Genes encoding putative effector proteins of the type III secretion
Genes encoding putative effector proteins of the type III secretion

07_Lecture_Presentation
07_Lecture_Presentation

...  Cells recognize each other by binding to molecules, often containing carbohydrates, on the extracellular surface of the plasma membrane  Membrane carbohydrates may be covalently bonded to lipids (forming glycolipids) or more commonly to proteins (forming glycoproteins)  Carbohydrates on the exte ...
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Magnesium transporter

This page links directly from the magnesium in biological systems page.Magnesium transporters are proteins that transport magnesium across the cell membrane. All forms of life require magnesium, yet the molecular mechanisms of Mg2+ uptake from the environment and the distribution of this vital element within the organism are only slowly being elucidated.In bacteria, Mg2+ is probably mainly supplied by the CorA protein and, where the CorA protein is absent, by the MgtE protein. In yeast the initial uptake is via the Alr1p and Alr2p proteins, but at this stage the only internal Mg2+ distributing protein identified is Mrs2p. Within the protozoa only one Mg2+ transporter (XntAp) has been identified. In metazoa, Mrs2p and MgtE homologues have been identified, along with two novel Mg2+ transport systems TRPM6/TRPM7 and PCLN-1. Finally, in plants, a family of Mrs2p homologues has been identified along with another novel protein, AtMHX.
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