Protein Secondary Structure
... What terminates an -helix? Statistically, a very high percentage (~60%) of helices are terminated by a single amino acid, Proline: ...
... What terminates an -helix? Statistically, a very high percentage (~60%) of helices are terminated by a single amino acid, Proline: ...
Protein Sequence and Structural Similarity
... Data Organelle nucleus, mitochondria, etc... (Proteomics) Which proteins are being produced in Nucleus which cells/tissues when? Which modified forms are present? ...
... Data Organelle nucleus, mitochondria, etc... (Proteomics) Which proteins are being produced in Nucleus which cells/tissues when? Which modified forms are present? ...
A Comparative Genomic Method for Computational
... – 9mers resembling binding site occur frequently in E. coli genome – not all sites matching consensus are actually bound by DnaA (ftsAQ) – some experimentally conserved binding sites differ from consensus – known DnaA regulated genes not functionally related (replication, lipid synthesis, house keep ...
... – 9mers resembling binding site occur frequently in E. coli genome – not all sites matching consensus are actually bound by DnaA (ftsAQ) – some experimentally conserved binding sites differ from consensus – known DnaA regulated genes not functionally related (replication, lipid synthesis, house keep ...
Immunodetection of the expression of microsomal proteins encoded
... disease termed type 1b glycogen storage disease. The cDNA encoding a liver transporter for glucose 6-phosphate was cloned and was found to be mutated in patients suffering from glycogen storage disease 1b. While related mRNAs have been described in liver and other tissues, the encoded protein(s) has ...
... disease termed type 1b glycogen storage disease. The cDNA encoding a liver transporter for glucose 6-phosphate was cloned and was found to be mutated in patients suffering from glycogen storage disease 1b. While related mRNAs have been described in liver and other tissues, the encoded protein(s) has ...
- blogs@NTU
... confirming the sensitivity of our approach, the purity of the vesicles and its ability to detect novel protein interactions. Vesicle tethering components of the SYP61 compartment A variety of proteins with a role in membrane trafficking were identified in the isolated SYP61 compartment, including YI ...
... confirming the sensitivity of our approach, the purity of the vesicles and its ability to detect novel protein interactions. Vesicle tethering components of the SYP61 compartment A variety of proteins with a role in membrane trafficking were identified in the isolated SYP61 compartment, including YI ...
H 2 O Reabsorption
... ~70% of Filtrate is – Small plasma proteins reabsorbed in PCT – Some urea and uric acid Na+ is actively reabsorbed: First – simple diffusion: Then – 1o active transport: ...
... ~70% of Filtrate is – Small plasma proteins reabsorbed in PCT – Some urea and uric acid Na+ is actively reabsorbed: First – simple diffusion: Then – 1o active transport: ...
Membrane Protein Expression in Cell
... continuous development of new applications significantly promotes the distribution of this technology. Membrane protein synthesis by cell-free expression does not appear to be restricted by origin, size or topology of the target, and its global application is therefore a highly valuable characterist ...
... continuous development of new applications significantly promotes the distribution of this technology. Membrane protein synthesis by cell-free expression does not appear to be restricted by origin, size or topology of the target, and its global application is therefore a highly valuable characterist ...
Leishmania Flagellum
... the tip of the flagellum [33]. Its main constituents are two structurally related proteins, PFR1 and PFR2 [33,34], which, as other cytoskeleton-associated proteins, remain insoluble after treatment with non-ionic detergents [35,36]. When expressed as fusion proteins with GFP at their N-terminus, PFR ...
... the tip of the flagellum [33]. Its main constituents are two structurally related proteins, PFR1 and PFR2 [33,34], which, as other cytoskeleton-associated proteins, remain insoluble after treatment with non-ionic detergents [35,36]. When expressed as fusion proteins with GFP at their N-terminus, PFR ...
BCL-2 Family Proteins: Critical Checkpoints of Apoptotic
... : gateway to the mitochondrial pathway of apoptosis 1. BAX and BAK fail to release cytochrome c 2. Activation of BAX AND BAK during apoptosis 3. Unlike BAX, BAK monomers are integrated into the MOM 4. Mitochondrial intramembranous homo-oligomerization of BAX & BAK is a prime candidate mechanism of M ...
... : gateway to the mitochondrial pathway of apoptosis 1. BAX and BAK fail to release cytochrome c 2. Activation of BAX AND BAK during apoptosis 3. Unlike BAX, BAK monomers are integrated into the MOM 4. Mitochondrial intramembranous homo-oligomerization of BAX & BAK is a prime candidate mechanism of M ...
Assembly and maintenance of the sarcomere night and day
... kinase domain, and also serves as a molecular spring.16 The N-terminus of titin spans the Z-disc and contains several small motifs termed z-repeats of 45 amino acids each, sandwiched between flanking regions containing Ig domains.17,18 Linking this region to GFP demonstrated that the z-repeats play ...
... kinase domain, and also serves as a molecular spring.16 The N-terminus of titin spans the Z-disc and contains several small motifs termed z-repeats of 45 amino acids each, sandwiched between flanking regions containing Ig domains.17,18 Linking this region to GFP demonstrated that the z-repeats play ...
The effect of pH on the digestion of proteins in vitro by pepsin
... It is evident from our results that all the proteins studied were most rapidly digested at pHs near z and that, although some proteolysis occurred at pH 4, there was no indication of a second peak of proteolytic activity at pH 3-5-4. There is general agreement that pepsin causes optimal proteolysis ...
... It is evident from our results that all the proteins studied were most rapidly digested at pHs near z and that, although some proteolysis occurred at pH 4, there was no indication of a second peak of proteolytic activity at pH 3-5-4. There is general agreement that pepsin causes optimal proteolysis ...
y. Cell Set. Suppl. ¡1, 1-11 (1989) Printed in
... mitochondrial RNAs and a few (13 in humans) of the mitochondrial proteins. All the other hundreds of mitochondrial proteins, and probably also several mitochondrial RNAs, are encoded by nuclear genes and imported into the mitochondria. In spite of their genetic semi-autonomy, mitochondria are thus p ...
... mitochondrial RNAs and a few (13 in humans) of the mitochondrial proteins. All the other hundreds of mitochondrial proteins, and probably also several mitochondrial RNAs, are encoded by nuclear genes and imported into the mitochondria. In spite of their genetic semi-autonomy, mitochondria are thus p ...
Does a backwardly read protein sequence have a unique native state?
... the capping properties of helical termini (Presta and Rose, 1988; Richardson and Richardson, 1988). The first helix is fairly well capped at the N-terminus by Asnl2, and the Cterminus by His 19. The second helix N-cap Asn26-Glu25Glu26 is perfect, while the C-cap is marked only by the Lys36 residue. ...
... the capping properties of helical termini (Presta and Rose, 1988; Richardson and Richardson, 1988). The first helix is fairly well capped at the N-terminus by Asnl2, and the Cterminus by His 19. The second helix N-cap Asn26-Glu25Glu26 is perfect, while the C-cap is marked only by the Lys36 residue. ...
Plant organelle proteomics
... achieved. These methods are often referred to as shotgun proteomics. One such approach, MudPIT (multidimensional protein identification technology [20]), involves a solution phase digestion of proteins to peptides and then multi-dimensional chromatographic separation of peptides before mass spectrom ...
... achieved. These methods are often referred to as shotgun proteomics. One such approach, MudPIT (multidimensional protein identification technology [20]), involves a solution phase digestion of proteins to peptides and then multi-dimensional chromatographic separation of peptides before mass spectrom ...
Strain TrpC TrpB TrpA
... polarity on TrpB and TrpA as in (B). However, this mutant reverts (regains TrpC activity) so this explanation is very unlikely). 4). One could consider an insertion mutation in trpC that also causes polarity. The fact that it does revert indicates that it could be an insertion. Since mutant #1 does ...
... polarity on TrpB and TrpA as in (B). However, this mutant reverts (regains TrpC activity) so this explanation is very unlikely). 4). One could consider an insertion mutation in trpC that also causes polarity. The fact that it does revert indicates that it could be an insertion. Since mutant #1 does ...
2.2 Membrane Structure and Functions
... and other components of one half of the lipid bilayer differ from those that make up the other half of the bilayer. This reflects the differences in the functions performed by each half of the membrane. For example, a range of glycolipids and carbohydrate groups attach to proteins on the external hal ...
... and other components of one half of the lipid bilayer differ from those that make up the other half of the bilayer. This reflects the differences in the functions performed by each half of the membrane. For example, a range of glycolipids and carbohydrate groups attach to proteins on the external hal ...
A Few Good Domains
... (Soluble NSF Attachment protein [SNAP] Receptors). SNARE proteins are believed to mediate most, if not all, cellular membrane fusion events. Most SNAREs are Cterminally anchored integral membrane proteins capable of entering into a coiled-coil interaction with other SNARE proteins. All SNARE protein ...
... (Soluble NSF Attachment protein [SNAP] Receptors). SNARE proteins are believed to mediate most, if not all, cellular membrane fusion events. Most SNAREs are Cterminally anchored integral membrane proteins capable of entering into a coiled-coil interaction with other SNARE proteins. All SNARE protein ...
Molecular Components of the Signal Sequence that Function in the
... One of the characteristic phenotypes exhibited by strains carrying the 42-1 fusion is related to the inability of the cell to export the LamB-LacZ hybrid protein efficiently. When cells containing this gene fusion are grown in the presence of maltose to induce high-level synthesis of the hybrid prot ...
... One of the characteristic phenotypes exhibited by strains carrying the 42-1 fusion is related to the inability of the cell to export the LamB-LacZ hybrid protein efficiently. When cells containing this gene fusion are grown in the presence of maltose to induce high-level synthesis of the hybrid prot ...
The Structure and Topology of Protein Serine/Threonine
... by four invariant aspartate residues and a non-conserved Glu residue (Figure 86.2b) [19]. These residues are situated at the top of the central -sandwich that forms a shallow channel suitable for the dephosphorylation of phosphoserine- and phosphothreonine-containing proteins. Six water molecules c ...
... by four invariant aspartate residues and a non-conserved Glu residue (Figure 86.2b) [19]. These residues are situated at the top of the central -sandwich that forms a shallow channel suitable for the dephosphorylation of phosphoserine- and phosphothreonine-containing proteins. Six water molecules c ...