De Novo Pyrimidine Nucleotide Synthesis Mainly
... 1982; Jund et al., 1988; Mitterbauer et al., 2002). FUR4 belongs to the Nucleobase:Cation Symporter1 (NCS1) family of transport proteins, also known as purine-related transporters (Saier et al., 2009; www.tcdb.org). The closest Arabidopsis homolog to this protein is encoded by At5g03555. The deduced ...
... 1982; Jund et al., 1988; Mitterbauer et al., 2002). FUR4 belongs to the Nucleobase:Cation Symporter1 (NCS1) family of transport proteins, also known as purine-related transporters (Saier et al., 2009; www.tcdb.org). The closest Arabidopsis homolog to this protein is encoded by At5g03555. The deduced ...
Docking Studies in Target Proteins Involved in Antibacterial Action
... aureus, and TopoIV and DHPS from Streptococcus pneumonia. The protein structures used in this work for IARS and Ddl were from Thermus thermophilus, although the best targets would be from S. aureus or Mycobacterium tuberculosis (also available in PDB). However, it was not possible to validate the do ...
... aureus, and TopoIV and DHPS from Streptococcus pneumonia. The protein structures used in this work for IARS and Ddl were from Thermus thermophilus, although the best targets would be from S. aureus or Mycobacterium tuberculosis (also available in PDB). However, it was not possible to validate the do ...
ch9 FA 11 - Cal State LA
... – GDP-bound tubulin can release only from “plus” end – GDP-bound tubulin cannot release from “minus” end or from central region ...
... – GDP-bound tubulin can release only from “plus” end – GDP-bound tubulin cannot release from “minus” end or from central region ...
- Warwick WRAP
... These findings were confirmed by transient expression of HA-tagged TIP3;1 [26]. Moreover, addition of an N-glycosylation sequon to a luminal loop of TIP3;1 resulted in the protein being glycosylated, but the N-linked glycan remained sensitive to endoglycosidase H (endo H) digestion. This further ind ...
... These findings were confirmed by transient expression of HA-tagged TIP3;1 [26]. Moreover, addition of an N-glycosylation sequon to a luminal loop of TIP3;1 resulted in the protein being glycosylated, but the N-linked glycan remained sensitive to endoglycosidase H (endo H) digestion. This further ind ...
Isolation, Cloning, and Sequencing of the Salmonella typhimurium dd1A Gene with Purification and Characterization of its Product, D-Alanine:D-Alanine Ligase (ADP Forming).
... fragile strain. Further investigation by these (Miyakawa et al., 1972) and other authors (Lugtenberg & van Schijndel-van Dam, 1973) indicated that the defect in the strain was in D-Ala-D-Ala ligase, as alanine racemase activity was normal in cell extracts and exogenous [14C]~-Ala-~-Ala was incorpora ...
... fragile strain. Further investigation by these (Miyakawa et al., 1972) and other authors (Lugtenberg & van Schijndel-van Dam, 1973) indicated that the defect in the strain was in D-Ala-D-Ala ligase, as alanine racemase activity was normal in cell extracts and exogenous [14C]~-Ala-~-Ala was incorpora ...
Endocytosis-like protein uptake in the bacterium Gemmata
... immunogold labeling of high-pressure frozen cells to investigate whether the internalized GFP was associated with any specific intracellular structures. Gold particles indicating presence of GFP in the paryphoplasm were often seen lining vesicle-like entities ca. 50–200 nm wide bounded by a single bi ...
... immunogold labeling of high-pressure frozen cells to investigate whether the internalized GFP was associated with any specific intracellular structures. Gold particles indicating presence of GFP in the paryphoplasm were often seen lining vesicle-like entities ca. 50–200 nm wide bounded by a single bi ...
composition changes with age of plaque
... The pH rise factor in saliva (sialin) which is a basic peptide containing Arg. It accelerate glucose uptake by salivary organisms, increase acid production & the formation of CO2 & base. The effect is obvious at low sugar conc. At high sugar conc. (>.5%) the effect is masked by increased acid produc ...
... The pH rise factor in saliva (sialin) which is a basic peptide containing Arg. It accelerate glucose uptake by salivary organisms, increase acid production & the formation of CO2 & base. The effect is obvious at low sugar conc. At high sugar conc. (>.5%) the effect is masked by increased acid produc ...
3 - Dr. Jerry Cronin
... • Na+-K+ pump works as antiporter – Pumps against Na+ and K+ gradients to maintain high intracellular K+ concentration and high extracellular Na+ concentration • Maintains electrochemical gradients essential for functions of muscle and nerve tissues • Allows all cells to maintain fluid volume ...
... • Na+-K+ pump works as antiporter – Pumps against Na+ and K+ gradients to maintain high intracellular K+ concentration and high extracellular Na+ concentration • Maintains electrochemical gradients essential for functions of muscle and nerve tissues • Allows all cells to maintain fluid volume ...
Liprin-α Functions - University of Oregon (SPUR)
... • Is the GAP domain necessary for synapse development? ...
... • Is the GAP domain necessary for synapse development? ...
Protein Sorting to the Storage Vacuoles of Plants: A Critical Appraisal
... of evidence now points to the presence of multiple functionally distinct vacuolar compartments, some existing side by side in the same cell. As a consequence, the plant Golgi apparatus is faced with the problem of recognizing proteins destined for lytic and storage vacuoles and segregating them indi ...
... of evidence now points to the presence of multiple functionally distinct vacuolar compartments, some existing side by side in the same cell. As a consequence, the plant Golgi apparatus is faced with the problem of recognizing proteins destined for lytic and storage vacuoles and segregating them indi ...
投影片 1
... Although prominent FRAT/GBP exhibits limited homology with Axin, the binding sites on GSK3 for FRAT/GBP and Axin may overlap to prevent the effect of FRAT/GBP to stabilize b-catenin in Wnt pathway. Using a yeast two-hybrid screen, we identified a novel protein, GSK3b interaction protein (GSKIP), whi ...
... Although prominent FRAT/GBP exhibits limited homology with Axin, the binding sites on GSK3 for FRAT/GBP and Axin may overlap to prevent the effect of FRAT/GBP to stabilize b-catenin in Wnt pathway. Using a yeast two-hybrid screen, we identified a novel protein, GSK3b interaction protein (GSKIP), whi ...
Chapter 3 PowerPoint - Hillsborough Community College
... • Secondary active transport – Depends on ion gradient that was created by primary active transport system – Energy stored in gradients is used indirectly to drive transport of other solutes • Low Na+ concentration that is maintained inside cell by Na+-K+ pump strengthens sodium’s drive to want to e ...
... • Secondary active transport – Depends on ion gradient that was created by primary active transport system – Energy stored in gradients is used indirectly to drive transport of other solutes • Low Na+ concentration that is maintained inside cell by Na+-K+ pump strengthens sodium’s drive to want to e ...
PathogenBioinformatics
... source providing the most current scientific literature on Listeria. Chain Link provides sources for purchasing the strains and microarrays. Click on Path Info. Here you will see information about the organism and associated references in outline format. As you scroll down, you will find a table und ...
... source providing the most current scientific literature on Listeria. Chain Link provides sources for purchasing the strains and microarrays. Click on Path Info. Here you will see information about the organism and associated references in outline format. As you scroll down, you will find a table und ...
UMCG
... Surface of L. mexicana* GAPDH with NAD bound. •Note: Leishmania mexicana GAPDH is ~77% sequence identical to Trypanosoma brucei GAPDH and all residues in the region of interest are identical in these two pathogenic “Trypanosomatids”. So these two enzymes are used interchangeably. ...
... Surface of L. mexicana* GAPDH with NAD bound. •Note: Leishmania mexicana GAPDH is ~77% sequence identical to Trypanosoma brucei GAPDH and all residues in the region of interest are identical in these two pathogenic “Trypanosomatids”. So these two enzymes are used interchangeably. ...
Automatically Extracting Structured Information from Biomedical Text University of Texas at Austin
... Other recent studies have identified human cyclin D1 (PRAD1) as a putative G1 cyclin and candidate proto-oncogene. However, the specific enzymatic activities and, hence, the precise biochemical mechanisms through which cyclins function to govern cell cycle progression remain unresolved. In the prese ...
... Other recent studies have identified human cyclin D1 (PRAD1) as a putative G1 cyclin and candidate proto-oncogene. However, the specific enzymatic activities and, hence, the precise biochemical mechanisms through which cyclins function to govern cell cycle progression remain unresolved. In the prese ...
SLC_ABCs_2013 - Jianhai Du Lab @ West Virginia University
... The SLC gene nomenclature system was originally established in the 1990s by Matthias Hediger in collaboration with Phyllis McAlpine, the first chair of the HGNC, and has since been maintained and extended in collaboration with Elspeth Bruford who now leads the HGNC. In 2004, a special mini-review ser ...
... The SLC gene nomenclature system was originally established in the 1990s by Matthias Hediger in collaboration with Phyllis McAlpine, the first chair of the HGNC, and has since been maintained and extended in collaboration with Elspeth Bruford who now leads the HGNC. In 2004, a special mini-review ser ...
AHM1, a Novel Type of Nuclear Matrix–Localized
... structure between helices II and III and solvent-accessible residues are indicated with (#) and (•), respectively. Conserved residues (⬎50% in the alignment) are highlighted, and related residues (hydrophobic or basic) are in boldface. Asterisks denote the ends of proteins. Amino acid positions of t ...
... structure between helices II and III and solvent-accessible residues are indicated with (#) and (•), respectively. Conserved residues (⬎50% in the alignment) are highlighted, and related residues (hydrophobic or basic) are in boldface. Asterisks denote the ends of proteins. Amino acid positions of t ...
Protein aggregation in bacteria: the thin boundary
... binding to certain sensor dye molecules such as Congo red and thioflavin-T and as mentioned above cross-b-sheet structure (Garcı́a-Fruitós et al., 2005). The degree of bsheet organization is, however, variable in the different aggregate forms, and the highest degree of order is commonly thought to ...
... binding to certain sensor dye molecules such as Congo red and thioflavin-T and as mentioned above cross-b-sheet structure (Garcı́a-Fruitós et al., 2005). The degree of bsheet organization is, however, variable in the different aggregate forms, and the highest degree of order is commonly thought to ...
Part A: Amino Acids and Peptides
... Name one possible peptide sideproduct that would form if the protein simply activated both ends of the three amino acids shown above. ...
... Name one possible peptide sideproduct that would form if the protein simply activated both ends of the three amino acids shown above. ...
FTIR Analysis of Protein Structure
... experiment carried out at pH 6.04 and 25°C are show in Figure 10a. To see which elements of secondary structure were affected the most during this experiment, Figure 11 plots the relative intensity of each peak as a function of time along with assignments for each. A logarithmic scale is used for ti ...
... experiment carried out at pH 6.04 and 25°C are show in Figure 10a. To see which elements of secondary structure were affected the most during this experiment, Figure 11 plots the relative intensity of each peak as a function of time along with assignments for each. A logarithmic scale is used for ti ...
Chapter 15. Recognition of foreign molecules by the immune system
... a lesser extent Ser415) promotes CD4 internalization. These residues are exposed in the complex, but the dileucine internalization motif is buried (leucines 413 and 414) (A). (B) The structured region of the CD8 complex is more modest; it consists of the Lck hairpin (red) and a 9-residue segment of ...
... a lesser extent Ser415) promotes CD4 internalization. These residues are exposed in the complex, but the dileucine internalization motif is buried (leucines 413 and 414) (A). (B) The structured region of the CD8 complex is more modest; it consists of the Lck hairpin (red) and a 9-residue segment of ...
PROTEIN METABOLISM
... these aminotransferases,leak from the injured heart cells into the bloodstream. Measurements of the blood serum concentrations of the two aminotransferases by the SGPT and SGOT tests (S for serum)—and of another enzyme, creatine kinase, by the SCK test— can provide information about the severity of ...
... these aminotransferases,leak from the injured heart cells into the bloodstream. Measurements of the blood serum concentrations of the two aminotransferases by the SGPT and SGOT tests (S for serum)—and of another enzyme, creatine kinase, by the SCK test— can provide information about the severity of ...
Membrane Proteins: Capturing the signal | eLife
... existence of this signal peptide (Blobel and Dobberstein, 1975), and the signal recognition particle (SRP), which actively targets the proteins to the endoplasmic reticulum, was also eventually identified (Walter and Blobel, 1981a). The SRP is thought to bind to and protect the signal peptide (which ...
... existence of this signal peptide (Blobel and Dobberstein, 1975), and the signal recognition particle (SRP), which actively targets the proteins to the endoplasmic reticulum, was also eventually identified (Walter and Blobel, 1981a). The SRP is thought to bind to and protect the signal peptide (which ...