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Interaction between the 5-HT system and the basal ganglia
Interaction between the 5-HT system and the basal ganglia

... PD, but it does not stop the progression of the disease. Moreover, long-term administration of L-DOPA induces motor complications, known as L-DOPA induced dyskinesias (LID), which have been related to adaptive changes of the serotonergic system. For example, a recent publication revealed that patien ...
Substance dependence trauma - Georgia School of Addiction
Substance dependence trauma - Georgia School of Addiction

... • Within the brain this chemical is associated with mood - a person's overall state of mind, how they feel about themselves and the external world at a point in time. • A lack of serotonin in the brain is associated with depression, which is why drugs called SSRIs (selective serotonin reuptake inhib ...
The Neurobiology of Depression
The Neurobiology of Depression

... Fatigue or loss of energy great effort trying to identify the genes at fault. So far, Feelings of worthlessness or excessive or inappropriate guilt though, those genes have evadIndecisiveness or diminished ability to think or concentrate ed discovery, perhaps because a predisposition to depression R ...
File - Wk 1-2
File - Wk 1-2

... interstitial fluid (and may undergo another circuit of the system) and are therefore not eliminated or they undergo passive tubular reabsorption back into the urine, but this process requires a lot of energy and is largely inefficient  Drugs bound to plasma proteins (most commonly albumin) cannot f ...
曹永孝
曹永孝

... The chemical transmitter dopamine is formed from the precursors tyrosine and L-dopa and is stored in vesicles. In the treatment of Parkinson's disease, L-dopa is given, and is converted to dopamine. This compensates for the patient's lack of dopamine. Dopamine nerve pathways in the brain. Arvid Carl ...
How Alcohol Enters the Body
How Alcohol Enters the Body

... probably believe that you are functioning better than you really are. ( * —As of July, 2004 ALL states had passed .08 BAC Per Se Laws. The final one takes effect in August of 2005.) 0.10 — 0.125 BAC: impairment of motor coordination and loss of good judgment. Speech may be slurred; balance, vision, ...
Chapter 8 Cholinoceptor
Chapter 8 Cholinoceptor

Sample letter to specialist: Managing acute pain in patients
Sample letter to specialist: Managing acute pain in patients

... This patient is currently receiving methadone daily, prescribed by myself. People on methadone tend to be more pain sensitive than those not on long-term opioid agonist maintenance, due to a down-regulation of their endogenous opioid receptors. Acetaminophen and NSAIDs are compatible with methadone ...
No Slide Title
No Slide Title

... • Antihistamine – One of the first effective ...
presentation source - NAU jan.ucc.nau.edu web server
presentation source - NAU jan.ucc.nau.edu web server

... percentage of the drug is changed from the original mother compound into some intermediate metabolite. All of the drug then passes out into the systemic circulation as 1) the intact drug plus its 2) changed intermediates. ...
Amphetamines Addiction
Amphetamines Addiction

OPTION D: CORE ENVIRONMENTAL CHEMISTRY
OPTION D: CORE ENVIRONMENTAL CHEMISTRY

Similarities and Differences Between Brand Name and
Similarities and Differences Between Brand Name and

... Generic and brand name drugs have identical active ingredients, and generic drugs must meet Health Canada’s standards for bioequivalence. Bioequivalent drug formulations have the same bioavailability; that is, the same rate and extent of absorption. New drug formulations must meet standards set by H ...
What is a Clinical Pharmacist?
What is a Clinical Pharmacist?

... Augmented Renal Clearance Younger patients (<50 yrs old) with “normal” renal function and some type of inflammatory response Especially with fluid loads or pressors ...
Effects of the histamine H3 receptor antagonist ABT
Effects of the histamine H3 receptor antagonist ABT

... Background: The strong correlation between central histaminergic and cholinergic pathways on cognitive processes has been reported extensively. However, the role of histamine H3 receptor mechanisms interacting with nicotinic mechanisms has not previously been extensively investigated. Methods: The c ...
Cholinergics and Anticholinergics
Cholinergics and Anticholinergics

... urinary system to promote urination  Results in contraction of the detrusor muscle and relaxation of the urinary sphincter to facilitate emptying of the urinary bladder ...
Urine drug screening Urine drug screens
Urine drug screening Urine drug screens

... the blood level to be too low to be detected. Drug metabolism may also affect detection. Opioids are ...
Postgraduate Course ERS Copenhagen 2005 The side
Postgraduate Course ERS Copenhagen 2005 The side

... without significant side-effects. There is also an opposing view that most patients with TB complete their treatment without serious adverse effects. What is the truth? Modern anti-TB chemotherapy regimens have been in use for >30 years. However, the frequency of severe complications is not well kno ...
MARIJUANA One of the world`s oldest known drugs
MARIJUANA One of the world`s oldest known drugs

... - labeling effects as “pleasant” e. Because of this learning process: - first time user - does not achieve euphoric “stoned” or “high” of repeat user ...
Club Drugs: MDMA, Gamma-Hydroxybutyrate (GHB)
Club Drugs: MDMA, Gamma-Hydroxybutyrate (GHB)

... and loss of consciousness. Effects occur about 30 minutes after ingestion, peak at two hours, and may last up to eight to 12 hours. The effects are much greater with the concurrent ingestion of alcohol or other sedating drugs. Some users experience hypotension, dizziness, confusion, visual disturban ...
baclofen
baclofen

... Myoclonus • The drugs used to treat myoclonus generally possess anticonvulsant properties), usually by enhancing gamma-aminobutyric (GABA) inhibitory activity. • Electrophysiologic evidence suggests that antimyoclonic drugs may exert different actions on the sequence of events responsible for myocl ...
outline27982 - American Academy of Optometry
outline27982 - American Academy of Optometry

... history of trusted performance. They act by binding to the GABA receptor, thus potentiating its affinity for GABA, which is the predominant inhibitor neurotransmitter of the brain. Leadings BZDs are alprazolam/Xanax, clonazepam/Klonopin, diazepam/Valium, and lorazepam/Ativan. e. Physical dependence ...
Chapter 12- Enemy Agents
Chapter 12- Enemy Agents

... ibuprofen (non-steroidal anti-inflammatory drugs, or NSAIDs), are readily available and widely used by Warfighters, who call these medications “Vitamin M.” Vitamin M refers to “Motrin.” These drugs are found in most medicine cabinets and in a medic’s pack to treat pain, reduce fever, and/or inflamma ...
presentation
presentation

... • Antihistamine – One of the first effective ...
05. Antimycobacterial drugs
05. Antimycobacterial drugs

... concurrently with other drugs when therapy with primary agents is ineffective or contraindicated. ...
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Psychopharmacology



Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.
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