lec#9 done by Dareen Mashaqbeh
... agonist ,it produces lower Vmax than the full agonist “ . Therefore both are potent by having similar ED50 . The difference between A and C that one of them is more potent than the other . the same goes for B and D in which B is more potent than D. -Partial agonist is utilized in specific cases . -R ...
... agonist ,it produces lower Vmax than the full agonist “ . Therefore both are potent by having similar ED50 . The difference between A and C that one of them is more potent than the other . the same goes for B and D in which B is more potent than D. -Partial agonist is utilized in specific cases . -R ...
Drug metabolism2
... Retard the metabolism and excretion of the inhibitor and coadministered drugs Prolong the action of the inhibitor and co-administered drugs→ increased pharmacological activity. ...
... Retard the metabolism and excretion of the inhibitor and coadministered drugs Prolong the action of the inhibitor and co-administered drugs→ increased pharmacological activity. ...
COMPLICATIONS AND MANAGEMENT 14 JULY 2010
... Patients rarely develop chronic liver disease after an acute severe DILI. Patients with cholestatic/mixed liver disease were more prone to developing chronic injury (9%), than those with the hepatocellular form ...
... Patients rarely develop chronic liver disease after an acute severe DILI. Patients with cholestatic/mixed liver disease were more prone to developing chronic injury (9%), than those with the hepatocellular form ...
Chapter 10
... conversion of dihydrofolic acid to THF (needed for purine synthesis in DNA) Humans obtain folic acid from diet; metabolism ...
... conversion of dihydrofolic acid to THF (needed for purine synthesis in DNA) Humans obtain folic acid from diet; metabolism ...
A. Glucocorticoid drugs
... Suppressing immunological functions and allergy a) inducing apoptosis of T and B lymphocytes b) inhibiting transcription factor activity(eg. AP1, NFB): ...
... Suppressing immunological functions and allergy a) inducing apoptosis of T and B lymphocytes b) inhibiting transcription factor activity(eg. AP1, NFB): ...
Pharmacology of Local Anesthetics
... heart failure may be unusually sensitive to these drugs. Some amides are partially excreted unchanged in the urine. ...
... heart failure may be unusually sensitive to these drugs. Some amides are partially excreted unchanged in the urine. ...
John Nagelhout
... about the use by nonanesthesiologists of propofol sedation. The short action of remimazolam may turn this dispute into a sideshow by offering the relative safety of benzodiazepine sedation combined with rapid clear-headed recovery. More interestingly, might remimazolam allow us to extend or enhance ...
... about the use by nonanesthesiologists of propofol sedation. The short action of remimazolam may turn this dispute into a sideshow by offering the relative safety of benzodiazepine sedation combined with rapid clear-headed recovery. More interestingly, might remimazolam allow us to extend or enhance ...
Steinberg – Medication Management of Behaviors in RCFEs
... Some Things (and People) Age Better Than Others ...
... Some Things (and People) Age Better Than Others ...
(2-aminoethyl) imidazole
... analgesic and anticholinergic effects，usually with side reaction like somnolence, dizzy, oral dryness. But incidence rate of gastrointestine reaction is low. Some of drugs could be applied in the treatment of insomnia. • For those aminoether with two aromatic group，the activity of Sisomer is usually ...
... analgesic and anticholinergic effects，usually with side reaction like somnolence, dizzy, oral dryness. But incidence rate of gastrointestine reaction is low. Some of drugs could be applied in the treatment of insomnia. • For those aminoether with two aromatic group，the activity of Sisomer is usually ...
Central Nervous System Depressants Community Mental Health
... some possibilities (Lehne, 2007, 182). Our brain makes substances called “endorphins” which temporarily help us by decreasing pain perception. Opioid medications and illegal drugs “fit” the in some of the same places (“mu” brain cell receptors) as our natural endorphins do. This “fit” is frequently ...
... some possibilities (Lehne, 2007, 182). Our brain makes substances called “endorphins” which temporarily help us by decreasing pain perception. Opioid medications and illegal drugs “fit” the in some of the same places (“mu” brain cell receptors) as our natural endorphins do. This “fit” is frequently ...
Document
... high levels of polymorphism These have been shown to affect the response of individuals to many drugs Codeine ...
... high levels of polymorphism These have been shown to affect the response of individuals to many drugs Codeine ...
Autonomic nervous system
... system(NS) and the endocrine system These two systems have several common properties, which include: high-level integration in the brain the ability to influence processes in distant regions of the body extensive use of negative feedback both systems use chemicals for the transmission of i ...
... system(NS) and the endocrine system These two systems have several common properties, which include: high-level integration in the brain the ability to influence processes in distant regions of the body extensive use of negative feedback both systems use chemicals for the transmission of i ...
Recognizing Drug Use in Adolescents
... cleaning solutions, gasoline, and office supplies including correction fluid, adhesives, and permanent markers. Users may have stains around the mouth, nose, or on their hands, and fumes on their clothing. Other information: Inhalants can be ingested in a variety of ways, including inhaling directly ...
... cleaning solutions, gasoline, and office supplies including correction fluid, adhesives, and permanent markers. Users may have stains around the mouth, nose, or on their hands, and fumes on their clothing. Other information: Inhalants can be ingested in a variety of ways, including inhaling directly ...
Who`s Doing What?
... impending overdose), respiratory depression, greatly reduced heart rate, and coma/death Thought to lower dopamine levels – can induce sleep, but when the user awakes, can be very aroused and active Withdrawal can be severe/difficult – may include seizures Has been used as a “date rape” drug (i ...
... impending overdose), respiratory depression, greatly reduced heart rate, and coma/death Thought to lower dopamine levels – can induce sleep, but when the user awakes, can be very aroused and active Withdrawal can be severe/difficult – may include seizures Has been used as a “date rape” drug (i ...
Blood Brain Barrier
... • Gabapentin • Ketorolac • Midazolam • Octreotide • Neostigmine • Ziconitide (Prialt)* ...
... • Gabapentin • Ketorolac • Midazolam • Octreotide • Neostigmine • Ziconitide (Prialt)* ...
NEUROMUSCULAR STRESSORS
... Less effective with prolonged use Drug holiday Hospitalize during drug holiday Adjunctive therapy with Amantadine ...
... Less effective with prolonged use Drug holiday Hospitalize during drug holiday Adjunctive therapy with Amantadine ...
young old
... dosage regimen. There is no evidence that there is any increase in pharmacodynamic sensitivity to the therapeutic effects of the cardiac glycosides; in fact, animal studies suggest a possible decrease in therapeutic sensitivity. On the other hand, there is probably an increase in sensitivity to the ...
... dosage regimen. There is no evidence that there is any increase in pharmacodynamic sensitivity to the therapeutic effects of the cardiac glycosides; in fact, animal studies suggest a possible decrease in therapeutic sensitivity. On the other hand, there is probably an increase in sensitivity to the ...
Drug interactions and lethal drug combinations
... overdosage, but when alcohol or a barbiturate is taken at the same time the suicidal attempt may be successful. Drugs which modify the function of sympathetic nerve terminals can change the pharmacological effects of other drugs acting on the system. For example, antihypertensive drugs which act by ...
... overdosage, but when alcohol or a barbiturate is taken at the same time the suicidal attempt may be successful. Drugs which modify the function of sympathetic nerve terminals can change the pharmacological effects of other drugs acting on the system. For example, antihypertensive drugs which act by ...
Chapter 9 Drugs
... • Drugs that have been approved for medical use are placed in Schedules II-V – the fact that a drug has been approved for medical uses does not change when it becomes a controlled substance ...
... • Drugs that have been approved for medical use are placed in Schedules II-V – the fact that a drug has been approved for medical uses does not change when it becomes a controlled substance ...
Drug and Alcohol Policy - Frederick Community College
... Frederick Community College is committed to an alcohol, tobacco, and drugfree learning and working environment and adheres to the responsibilities set forth in applicable local, state, and federal laws. All members of the College community, visitors, and guests are required to comply. The College pr ...
... Frederick Community College is committed to an alcohol, tobacco, and drugfree learning and working environment and adheres to the responsibilities set forth in applicable local, state, and federal laws. All members of the College community, visitors, and guests are required to comply. The College pr ...
Psychopharmacology
Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.