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Gastrointestinal Disorders and Medication Management Drugs for
Gastrointestinal Disorders and Medication Management Drugs for

... o Diarrhea with magnesium based products o Constipation with aluminum & calcium based products o May contain Simethicone, an anti-gas agent Dosing o 1-3 hours pc & hs o Follow with water o Space antacids 1-2 hours apart from other medications Cautious Use o Electrolyte imbalance o Renal insufficienc ...
Analgesic Drugs
Analgesic Drugs

... \ plasma protein binding predominantly inactivated in the liver by conjugation to active or inactive metabolites & are excreted in the urine or bile Most Opiods have a volume of distribution several times greater than total body water. Total clearance similar to hepatic blood flow. Entero- hepatic c ...
AODA Day 9 Cocaine and Inhalants
AODA Day 9 Cocaine and Inhalants

... heart rate, breathing rate, and 6. Your _____ temperature all go up, at the same time when body ___________ using cocaine, which may cause you to die, even on the first try. ...
Alcohol and Drug Related Disorders
Alcohol and Drug Related Disorders

... Intoxication – a reversible, substance specific set of symptoms related to using a particular substance. The person must display clinically significant maladaptive behaviors or personality changes. Intoxication is not diagnosed when someone simply ingests a substance that has the desired effect and ...
(1)
(1)

... • It induces several CYP 450 iso enzymes • Thus enhances its own metabolism as well as of other drugs including: Warfarin, OCPs, Corticosteroids, Anti-fungal drugs, Digitoxin, Protease inhibitors, NRTIs, etc. Increase dose; alternative method ...
Neuron and Nervous System Review Guide
Neuron and Nervous System Review Guide

... Neural Communication Neurotransmitters: chemical messengers that traverse the synaptic gaps between neurons Agonist – mimic neurotransmitters Example: Morphine mimics endorphins Antagonist – block neurotransmitters Example: Poison blocks muscle movement Acetylcholine (Ach) – Enables muscle action, l ...
Drugs Used in the Treatment of Gastrointestinal Diseases
Drugs Used in the Treatment of Gastrointestinal Diseases

... Clinical Uses of (PPIs) : Gastroesophageal Reflux (GERD): The most effective agents in all forms of EGRD Nonulcer Dyspepsia: Modest activity.10-20% more beneficial than a placebo Stress- Related Gastritis: Oral immediate- release omeprazole administered by nasogastric tube. For patients without a n ...
6GuN8Qo9Dfp1QZDN8ubBtuHr_F8SNcwjgzjV3UndOuNh4gNcd
6GuN8Qo9Dfp1QZDN8ubBtuHr_F8SNcwjgzjV3UndOuNh4gNcd

... 27. The symptoms of BPH are caused by a. pressure exerted by the prostate gland on urethra b. relaxation of bladder muscles c. shrinkage of the prostate gland d. relaxation of the prostate gland muscles e. non of the above 28. Which of the following TCA is used in the treatment of nocturnal enuresis ...
GENERAL PRINCIPLES OF CLINICAL PHARMACOLOGY
GENERAL PRINCIPLES OF CLINICAL PHARMACOLOGY

... meperidine, pentazocine, morphine) are absorbed intact from the small intestine and transported first via the portal system to the liver, where they undergo extensive metabolism. This process has been called a first-pass effect. Some orally administered drugs (eg, clonazepam, chlorpromazine) are mor ...
Pharmacokinetics
Pharmacokinetics

... extra layer of cells surrounding them (glial cells). However, fever/inflammation can make the membrane more permeable to other drugs ...
local anesthetics - Website of Neelay Gandhi
local anesthetics - Website of Neelay Gandhi

... 3. In nerve root, B and sensory C fibers blocked before A fibers  pain>sensation>motor (Pain fibers fire faster and have shorter AP duration therefore more susceptable to actions of LA 4. In PERIPHERAL nerve buncles, MOTOR neurons are on the OUTSIDE 5. In EXTREMITIES, afferent SENSORY fibers are at ...
2nd Lecture 1433
2nd Lecture 1433

... The extent to which the ligand/drug is capable of binding and remained bound to receptor.  High Affinity – the ligand binds well and remains bound long enough to activate the receptor.  Low Affinity – the ligand binds less well and may not remain bound long enough to activate the receptor. ...
Opioids The term opium comes from the Greek opos meaning juice
Opioids The term opium comes from the Greek opos meaning juice

... (goose bumps), sweating, nausea, vomiting and insomnia occur, along with psychological symptoms such as anxiety and dysphoria that often trigger renewed consumption. Other symptoms of withdrawal are diarrhea, tachycardia, high blood pressure and joint and muscle pain. Many opioid addicts repeatedly ...
MINISTRY OF HEALTH OF UZBEKISTAN
MINISTRY OF HEALTH OF UZBEKISTAN

... If, within 2-4 weeks of blood pressure can not be reduced to the desired level using medium-dose β-blocker, should not increase the dose of the drug, but to add a thiazide diuretic (hydrochlorothiazide, indapamide, chlorthalidone), dihydropyridine calcium channel blocker (amlodipine, nifedipine, fel ...
Treatments for Diabetes Mellitus
Treatments for Diabetes Mellitus

... • The correct mechanism for the action of TZD is still not know but drugs such as rosiglitazone and pioglitazone are on the market and shown effective in patients. • Like any drug these agents have side effects such as weight gain and an increase in subcutaneous fat mass. • For most patients, weight ...
Neuraxial Opioid-Induced Pruritus: A Review
Neuraxial Opioid-Induced Pruritus: A Review

... Morphine produces part of its analgesic effect through the release of serotonin.  There are dense concentration of serotonin receptors in the dorsal part of spinal cord & the nucleus of spinal tract of the trigeminal nerve in the medulla, in which opioid receptor density is also high.  These obser ...
3316 - Isomer Design
3316 - Isomer Design

... Health Canada Santé Canada ...
priorities for systematic reviews
priorities for systematic reviews

... (Technical) disinfectants should be moved as they have nothing to do with use on the skin. 17. Gastrointestinal drugs In line with the policy of using single drug products, antacids are listed as either aluminium salts or magnesium salts. In my opinion this is a drug class where there is a rationale ...
Assessing the Evidence: What Science Has To Say About the Prescribing
Assessing the Evidence: What Science Has To Say About the Prescribing

... Source: Ho, B. “Progressive structural brain abnormalities and their relationship to clinical outcome.” Arch Gen Psych 60 (2003):585-94. Andreasen, N. “Longitudinal changes in neurocognition during the first decade of schizophrenia illness.” International Congress on Schizophrenia Research (2005):34 ...
Drugs
Drugs

L8-drugs affecting breast milk and lactation
L8-drugs affecting breast milk and lactation

... woman are detectable in milk. • The concentration of drugs achieved in breast milk is usually low (< 1 %). • However, even small amounts of some drugs may be of significance for the suckling child. • There are many pharmacokinetic and pharmacodynamics changes in pediatrics. ...
drugs - Bio-Guru
drugs - Bio-Guru

... (CNS), where it affects the centers for thought processes and coordination • In low doses it may appear to increase a person’s confidence (Uninhibited behavior) • Higher doses cause irritability (anger), sadness (crying) • Extremely high doses can be poisonous - fatal ...
new-ff-Benzodiazepines-
new-ff-Benzodiazepines-

... physical dependence and tolerance which are treated by gradual withdrawal. Mechanism of Action Anxiolytics produce their effects by enhancing the GABAnergic transmission via an increase in chloride conductance. GABA is the major inhibitory neurotransmitter in CNS. GABAA receptors are ligand-gated ch ...
ppt - Department of Public Health Pharmacology & Tox.
ppt - Department of Public Health Pharmacology & Tox.

... Adverse effects, toxicity and drug interactions • Barbiturates decrease absorption and antifungal activity of Griseofulvin. • Griseofulvin is a microsomal enzyme inducer and promotes the biotransformation of concurrently administered drugs. • The combined use of ketoconazole and griseofulvin may le ...
Temple, Nahata et al. Drug Safety 2004
Temple, Nahata et al. Drug Safety 2004

... Options for Antidepressant Therapy • TCAs may be no better than placebo and may cause anticholinergic and cardiac ADEs • Higher risk of death with overdose • SSRIs appear effective; initiate low dose, titrate slow, adhere to avoid too low/high conc., monitor ...
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Psychopharmacology



Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.
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