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rajiv gandhi university of health sciences
rajiv gandhi university of health sciences

... property which is responsible for its therapeutic benefits against anxiety and depression.[2] Opipramol also acts as a low to moderate affinity antagonist for the D2, 5HT2, H1, H2, and muscarinic acetylcholine receptors. H1 and H2 receptor antagonism account for its antihistamine effects, and muscar ...
possible implications for pharmacotherapy of Alzheimer`s
possible implications for pharmacotherapy of Alzheimer`s

guidelines on emergency control of the acutely
guidelines on emergency control of the acutely

... 7. PROCYCLIDINE (5mg IM) injection must be available for acute dystonias. Repeat, if necessary, after 20 minutes. Maximum dose 20mg in 24 hours. 8. Avoid phenothiazines or other antipsychotics in acute alcohol withdrawal. There are separate guidelines for nonemergency alcohol withdrawal and detoxifi ...
Mental Illness
Mental Illness

... In psychotics, the disturbance of the mind is so great there may be a disintegration of the personality. They are unaware of anything being wrong and lose touch with reality. During acute attacks, odd behaviour occurs. This condition is generally not a reaction to circumstances and frequently no ext ...
Electronic Structure Based Classification of Neurotransmitters and
Electronic Structure Based Classification of Neurotransmitters and

... neurological or psychiatric symptoms and result in disease. Examples for disorders associated with the defects in neurotransmission are 1) Alzheimer’s disease caused by reduced synthesis of the neurotransmitter acetylcholine; and 2) Parkinson’s disease caused by the insufficient formation and action ...
Dangers Of Malpractice
Dangers Of Malpractice

... clear drugs out of the body, and the output of the heart begin to decrease. Since most people in their 30s or 40s are not given many prescription drugs, these changes alone do not usually lead to a large number of drug induced medical problems. Many of the adverse reactions discussed in this book, h ...
Controversial Feelings about Dopamine Receptors
Controversial Feelings about Dopamine Receptors

... vertebrate central nervous system (CNS) as well as the peripheral nervous system (PNS). The neurotransmitter dopamine (DA), a precursor of noradrenaline and adrenaline, is one of the main endogenous catecholamine ligand for DA receptors. Dopamine is a neuromodulator that is synthesized in neural and ...
Designer - RTI International
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Alkaloids * Natural nitrogenous secondary metabolites from plants
Alkaloids * Natural nitrogenous secondary metabolites from plants

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456 PHG

... 5- Steroids: are derivatives of cyclopentanophenanthrene e.g., estrogens, androgens, cholesterol, ergosterol. 6- Alkaloids: they are nitrogenous, crystalline or oily compounds. Usually basic in nature e.g., atropine, morphine, quinine, cocaine and reserpine. 7- Peptide hormones: these are active pri ...
Local Anaesthesia
Local Anaesthesia

... The first and most potent local anaesthetic agent, rarely used because of the problems of misuse. It is unique in it is ability to produce intense vasoconstriction. Half life 30 minutes. Dosage: Used as topical 4 – 10% solution  Maximum dose is 1.5 mg/kg – 100mg max.  Used intranasally during apic ...
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Pharmacokinetics and pharmacodynamics

... the same and all trough concentrations are the same • Happens when a drug is given repeatedly • The amount of drug being administered equals the amount of drug being eliminated • After the time of one half life has passed, the peak and trough concentrations are 50% of what they will be when they ach ...
Psychopharmacology
Psychopharmacology

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Dopamine 2016 - Intrinsic Activity

... What enables the human nervous system to acquire language and speech and which genetic candidates might have contributed to this capacity? Two human-specific amino acid substitutions in the transcription factor FOXP2 are outstanding candidates, given that they might have been positively selected dur ...
Tecfidera (dimethyl fumarate)
Tecfidera (dimethyl fumarate)

... - low levels of white blood cells (lymphopenia, leucopenia) in the blood. Reduced white blood cells could mean your body is less able to fight an infection. If you have a serious infection (such as pneumonia) - proteins (albumin) in urine - increase in levels of liver enzymes (ALT, AST) in the blood ...
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Side Effects of Vasodilator Therapy

... in the central nervous system decrease peripheral resistance. However, their primary pharmacological site of action is not at the vascular smooth muscle and are thus not considered as vasodilating antihypertensive drugs in this discussion. Direct acting vasodilating agents include hydralazine, minox ...
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SSRI`s - Seroxat User Group

... conjunction with a specific antibody against 5-hydroxytryptophan (5HTP) and found that 5-hydroxytryptamine (serotonin) was depleted by reserpine treatment. Their findings suggest that the targeted neurons synthesized more 5HTP by a process apparently stimulated by reserpine. (Fujimiya M, et al. Hist ...
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What do Medical Students need to know about

... choice exams ( MCQs) are often unreliable and measure only factual knowledge. • Problem solving MCQs give a better assessment * OSCE’s ( Objective Structured Clinical Exams) can be useful but station size is usually limited ...
A STUDY TO EVALUATE THE EFFECT OF SPARFLOXACIN ON PENTOBARBITONE... SLEEP IN MICE
A STUDY TO EVALUATE THE EFFECT OF SPARFLOXACIN ON PENTOBARBITONE... SLEEP IN MICE

Perphenazine Fact Sheet - The Main Line Center for the Family
Perphenazine Fact Sheet - The Main Line Center for the Family

... Perphenazine may induce bothersome side effects known as extrapyramidal symptoms. These are neurological disturbances caused by antipsychotics (or a neurological disorder) in the area of the brain that controls motor coordination. When disruption occurs in a particular area of the brain, it can prod ...
The Neurobiology of Addiction
The Neurobiology of Addiction

... glutamate signaling has been recognized recently as an important response to numerous drugs of abuse including amphetamines, benzodiazepines, cocaine, ethanol, nicotine, and opiates (for review, see Cunha-Oliveira et al. 2008; Kalivas et al. 2009; Koob 2003). Disruption of normal glutamate transmiss ...
MSR for 07 12 12 no methadone
MSR for 07 12 12 no methadone

... group vs 11% in the placebo group (all got behavioral treatment) Better abstinence rates with 7 day lead in ...
The anti-infectives
The anti-infectives

... pseudomembranous colitis. HEPATOTOXICITY can occur if the drug is taken in high doses with other hepatotoxic drugs. ◦ CNS- confusion, abnormal thinking and uncontrollable emotions. ◦ Hypersensitivity reactions ...
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Psychopharmacology



Psychopharmacology (from Greek ψῡχή, psȳkhē, ""breath, life, soul""; φάρμακον, pharmakon, ""drug""; and -λογία, -logia) is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior.The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain.Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their receptors is referred to as ""drug action"", and the widespread changes in physiological or psychological function is referred to as ""drug effect"". These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical synthesis in the laboratory.
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