• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Pituitary Hormones
Pituitary Hormones

... - MOA Unclear, its effects believed to be mediated through IGFs (Somatomedins) which are formed in the liver , kidneys, muscles and other tissues - GH stimulates growth of soft tissues and bones - ↑ lipolysis - ↑ gluconeogenesis & ↓ glucose utilization (diabetogenic effect) - PRL-like activity ...
Neuropharmacology I Parkinson`s Disease and Movement
Neuropharmacology I Parkinson`s Disease and Movement

... (wearing off and dyskinesias) New DA agonists are now used as primary therapy in many patients, especially ...
No Slide Title
No Slide Title

... spirit of a 1999 report from the Institute of Medicine, a unit of the National Academy of Sciences. “The institute was appropriately cautious in its endorsement of marijuana. It said the active ingredients of marijuana appeared useful for treating pain, nausea and the severe weight loss associated w ...
Week 8
Week 8

...  Hallucinations  Delusions  Thought disorder  Social withdrawal ...
Pharmacology Tutoring for Sedative Hypnotics and Antiemetics
Pharmacology Tutoring for Sedative Hypnotics and Antiemetics

... Which of the following is true of the mechanisms of barbiturates and benzodiazepines in terms of GABA channel opening? a. Barbiturates increase frequency while benzodiazepines increase duration of ...
What Is the Role of Neurotransmitter Systems in Cortical Seizures?
What Is the Role of Neurotransmitter Systems in Cortical Seizures?

... influencing these receptors are not so serious as those of antagonists of ionotropic glutamate receptors therefore their therapeutic index is better (Doherty and Dingledine 2002, Moldrich et al. 2003). Again, individual drugs act at different sites of ionotropic and/or metabotropic glutamate recepto ...
PSYCHOPHARMACOLOGY
PSYCHOPHARMACOLOGY

... BZ (benzodiazepines) ...
Typical antipsychotic drugs
Typical antipsychotic drugs

... Aetiology and pathogenesis ...
adrenergic system - lec-4 2008
adrenergic system - lec-4 2008

... The plasma concentration of a B adrenoceptor blocking drugs have a complex relation ship with there effects , first order kinetic usually apply to elimination of the drug from the plasma. But there decline in the receptor block is zero order Most B adrenoceptor blocking drugs can be: 1- given orally ...
181lec11
181lec11

...  Only short-term tolerance to LSD, no withdrawal, dependence or addiction  LSD not lethal at very high doses  Cross tolerance for hallucinogenic effect  Focus on 5-HT systems (structural similarity) ...
Dear Notetaker - Home Sign In Page
Dear Notetaker - Home Sign In Page

... receptors: need to add Tropicamide to get these effects o Increased effect with LA due to better absorption o Sympathetic tone varies in different people, is decreased in older people o Decreased effect in dark irides o Even 1/8% can rarely cause angle closure o Counteracts miotics, can be used in 2 ...
Newer Unregulated Drugs
Newer Unregulated Drugs

... are concentrated rather than raw plant material, at different levels of potency. Currently legal in UK. Made controlled drug in 2015 Linked to deaths in Europe. Reported to be strong and long acting. Has cropped up in numerous tablet designs sold as Ecstasy Substituted molecule based on JWH-018 (one ...
Autonomic Nervous System
Autonomic Nervous System

... mood inappropriation, paranoia (persecution mania) and hallucinations (voices) and Negative symptoms: withdrawal from society, flattened emotional responses, defect in selective attention (can’t distinguish between important and insignificant) Affects up to 1% of population, high suicide rate (10%) ...
userfiles/140/my files/powerpoint presentations/social_drugs_nmhs
userfiles/140/my files/powerpoint presentations/social_drugs_nmhs

... After 1 yr heart attack risk is 1/2 that of a smoker After 10 yrs lung cancer risk is 1/2 that of a smoker ...
chronic pain
chronic pain

... dysphoria. Delta receptors modulate mu receptor activity. Sigma receptors provide little to no analgesia. They are responsible for many of the adverse effects associated with opioids (dysphoria, hallucinations, respiratory and vasomotor stimulation). Some investigators classify sigma receptors as ph ...
Al Tmimi - Cardiovascular active medications tekst
Al Tmimi - Cardiovascular active medications tekst

... Inotropy means contraction of the heart muscles. This occurs when the actin and myosin (proteins) interact to each other. This reaction will be prevented by the action of two other proteins, troponin and tropomyocin. When intracellular calcium concentration is increased, contraction of the myocardiu ...
• • • • •
• • • • •

... • Aldosterone is a very powerful mineralocorticoid, but it has a week glucocorticoid activity. • Its release from the adrenal cortex is controlled by the renin-angiotensin system. • It acts on collecting tubules causing reabsorption of sodium, bicarbonate & water. Potassium & H + are lost in the uri ...
563 kB - recent advances remifentanil mgmc
563 kB - recent advances remifentanil mgmc

... • flumazenil is a specific benzodiazepine receptor antagonist • primarily available by injection only, • It reverses the effects of benzodiazepines by competitive inhibition at the benzodiazepine binding site on the GABA A receptor. ...
Antiemetic drugs
Antiemetic drugs

... – Domperidone; it does not cross the blood-brain barrier and therefore lacks the neurologic side effects of metoclopramide • Phenothiazine – Sedation, Hyperprolactinemia, Postural hypotension – Extrapyramidal effects e.g. dystonia and dyskinesia ...
Slide 1
Slide 1

... • Feedback regulation • Endocrine disorders: – Deficiency, or – Excess • Mechanisms of action • Uses of hormones /analogs: – Diagnostic use – Therapeutic use ...
The Autonomic Nervous System
The Autonomic Nervous System

... • Their duration of action is shorter than that of atropine. ...
Adrenergic Drugs - Nursing Pharmacology
Adrenergic Drugs - Nursing Pharmacology

... Salmeterol is appropriate for prevention of bronchospasms. Fluticasone is a corticosteroid that is not effective for acute bronchospasms. Advair Diskus is used for daily maintenance, not acute exacerbations. ...
Pharmacology 3a – Cholinomimetics
Pharmacology 3a – Cholinomimetics

... A cholinomimetic drug is one that mimics the action of acetylcholine. They are clinically important because they act on post-ganglionic muscarinic receptors. s NB:  ACh is of no therapeutic use as it does not differentiate between nicotinic and muscarinic receptors and is rapidly degraded  Nicotin ...
drugs acting on the respiratory system bronchial asthma
drugs acting on the respiratory system bronchial asthma

... preferable for the relief of acute attack of bronchial asthma. - Administered by inhalation or subcutaneously. Side effects include arrhythmia and worsening of angina pectoris, increase blood pressure, tremors etc. Contraindication: - hypertension, arrhythmia, 2- Ephedrine: compared to epinephrine, ...
On the Discovery and Development of Pimavanserin
On the Discovery and Development of Pimavanserin

... While screening numerous typical and atypical APDs, we discovered that most of the atypical APDs, including clozapine, had one activity in common which separated them from the typical antipsychotic agents. They were potent and fully efficacious inverse 5-HT2A agonists [25] and they were less or much ...
< 1 ... 45 46 47 48 49 50 51 52 53 ... 76 >

Cannabinoid receptor antagonist



The discovery of the endogenous cannabinoid system led to the development of CB1 receptor antagonists. The first cannabinoid receptor antagonist, rimonabant, was described in 1994. Rimonabant blocks the CB1 receptor selectively and it has been shown to decrease food intake and regulate body-weight gain. The prevalence of obesity worldwide is increasing dramatically and has a great impact on public health. The lack of efficient and well-tolerated drugs to cure obesity has led to an increased interest in research and development of cannabinoid antagonists. Cannabidiol, a naturally occurring cannabinoid, is a non-competitive CB1/2 antagonist.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report