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... MASCC No Routine Prophylaxis ...
Pharmacology and the Nursing Process, 4th ed. Lilley/Harrington
Pharmacology and the Nursing Process, 4th ed. Lilley/Harrington

Antidepressants and neuroleptic
Antidepressants and neuroleptic

... Correct answer = A. Because of its potent antimuscarinic activity, amitriptyline should not be given to patients with glaucoma because of the risk of acute increases in ocular pressure. The other antidepressants all lack antagonist activity at the muscarinic receptor. ...
Slide ()
Slide ()

Document
Document

... and vomiting.43,44 Several lines of evidence suggest that antagonism of 5-HT binding to 5-HT3 receptors on vagal afferents constitutes the predominant mechanism by which the 5-HT3 antagonists exert their antiemetic effect.39,45 During the past two decades, multiple studies have suggested that substa ...
Drugs for respiratory system
Drugs for respiratory system

... mechanism for clearing foreign material and secretions from the airway. In some conditions, such as inflammation or neoplasia, the cough reflex may become inappropriately stimulated and in such cases, antitussive drugs may be used. ...
The Fluorine Boom Continues as Benefits Become More Widespread
The Fluorine Boom Continues as Benefits Become More Widespread

... are concerned fluorine is usually more lipophilic than hydrogen, which makes the fluorinated compounds more fat soluble. This allows them to partition into membranes more easily and they have higher bioavailability. Several examples in the recent literature show that molecules useful as pharmaceutic ...
351 Pharmacology PNS 5th Lecture F
351 Pharmacology PNS 5th Lecture F

GABA Receptor Agonists for Treatment of Bronchoconstrictive
GABA Receptor Agonists for Treatment of Bronchoconstrictive

... • Many patients are not successfully treated using the inhaled glucocorticosteroids and/or bagonists normally used in asthma • Inhaled drugs are more difficult to administer, especially for children • Corticosteroids take several weeks to become effective; benefits wear off quickly without continued ...
The importance of residence and recognition time of drug
The importance of residence and recognition time of drug

... CADD SAR/QSAR ...
Time to Sleep Anesthesia Pharmacology Review
Time to Sleep Anesthesia Pharmacology Review

... H) Adverse Effects and Contraindications: Most significant concern is respiratory ...
SERIES ‘‘GENETICS OF ASTHMA AND COPD IN THE POSTGENOME ERA’’
SERIES ‘‘GENETICS OF ASTHMA AND COPD IN THE POSTGENOME ERA’’

... for HIV entry into macrophages, individuals who are homozygous for the CCR5 D 32 variant lack one of the key cell surface HIV receptors and thus are relatively resistant to the development of AIDS following HIV exposure [4]. The remaining common form of polymorphism occurs as a result of variable nu ...
Kinetics of metoclopramide effects on human 5
Kinetics of metoclopramide effects on human 5

... including general anesthetics and cannabinoids [3-51. 5-HT3 receptors are located in components that play a major role in the modulation of nausea and emesis [6,7]. Metoclopramide has been in use as an antiemetic and prokinetic agent for many years. The drug is known for its D, (dopamine,) receptor ...
PSYCHOPHARMACOLOGY
PSYCHOPHARMACOLOGY

Pharmacologyonline 3: 7-22 (2011) Newsletter Tamboli et al.
Pharmacologyonline 3: 7-22 (2011) Newsletter Tamboli et al.

... contributes to the complex action of lobeline. Thus, the effects of lobeline on N-methyl-D-aspartate (NMDA), serotonin and NE release may be attributed to the complex action of lobeline. All of this suggests that nicotine and lobeline act on nAChR via a non-common CNS mechanism. Thus, the pharmacolo ...
Antipsychotics
Antipsychotics

...  More effective than typical agents with regard to negative symptoms  Much lower incidence of parkinsonian symptoms and anticholinergic effects than typical agents  TD does occur but at much lower incidence  Elevated risk of metabolic side effects ...
The behavioral pharmacology of hallucinogens
The behavioral pharmacology of hallucinogens

... assessing mechanisms of action of these drugs that informs their subjective effects in man would be especially useful. The main methodology presently employed in this regard is drug discrimination. In a typical discrimination task, an animal is trained to emit one response during experimental sessio ...
GABA - the Houpt Lab
GABA - the Houpt Lab

... Give patients DOPA to boost DA synthesis ...
2,5-Dimethoxy-4-methylphenyl
2,5-Dimethoxy-4-methylphenyl

... serotonin receptors, (a) it displays about a 1000-fold selectivity for 5-HT2 versus 5-HTlc sites and (b)it has been used as a “5-HT2-selective”antagonist. Because spiperone is a behaviorally disruptive agent, it is not suitable for use in drug-discrimination studies. Using the spiperone molecule as ...
Antipsychotic Drugs
Antipsychotic Drugs

... General View • Classification: anti-schizophrenic drugs (antipsychotic drugs or neuroleptics), antimanic drug, antidepressants or antianxiolytics. • Pharmacologically, they are characterised as dopamine receptor antagonists, though many of them also act on other targets, particularly 5-HT receptors ...
Drug acting on autonomic and central nervous systems
Drug acting on autonomic and central nervous systems

... norepinephrine from adrenergic neurons. The drug can increase blood pressure by both vasoconstriction and cardiac stimulation and it will relax bronchiolar smooth muscle. Ephedrine is used orally in many cough and cold preparations for its decongenstant activity. Ephedrine will pass through blood-br ...
What is schizophrenia
What is schizophrenia

... ineffective for vomiting induced by stimulating vestibules of ears (motion sickness). effective for nausea and vomiting, ...
Ch 4 lec 1
Ch 4 lec 1

... Dose-Response Curve – a graph of the magnitude of an effect of a drug as a function of the amount of drug ...
Psychology 250 - Rio Hondo College
Psychology 250 - Rio Hondo College

... • Attack the enzymes responsible for the deterioration of NTs in the synaptic cleft ...
Anti-platelet agents
Anti-platelet agents

... • Is not a very effective antithrombotic drug • Dipyridamole also has a vasodilatory effect and should be used with caution in patients with severe coronary artery disease; chest pain may be aggravated in patients with underlying coronary artery disease who ...
< 1 ... 73 74 75 76 77 78 79 80 81 ... 107 >

NK1 receptor antagonist

Neurokinin 1 (NK1) antagonists are a novel class of medications that possesses unique antidepressant, anxiolytic, and antiemetic properties. The discovery of neurokinin 1 (NK1) receptor antagonists was a turning point in the prevention of nausea and vomiting associated with cancer chemotherapy.An example of a drug in this class is aprepitant. Chemotherapy-induced emesis appears to consist of acute and delayed phases. So far, the acute phase emesis responds to 5-HT3 antagonists while the delayed phase remains difficult to control. The discovery and development of NK1 receptor antagonists have elicited antiemetic effect in both acute and especially in delayed phases of emesis.The first registered clinical use of NK1 receptor antagonists was the treatment of emesis, associated with cancer chemotherapy.
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