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Theoretical study of primary reaction of Pseudozyma
Theoretical study of primary reaction of Pseudozyma

... performed on these states in order to compute KIEs for substitution on key atoms C1, O1 and O2. Analysis of results listed in Table 3 shows that isotopic substitution of C1 and O2 does not render differences between TS1 and TS3. Obviously, the change in orbital hybridization of these two atoms in st ...
Unit5C - OCCC.edu
Unit5C - OCCC.edu

... Example: Write the complete ionic and net ionic equations for the reaction. Which element is oxidized? What is the oxidizing ...
Chapter 8
Chapter 8

... • Potential energy is energy that matter possesses because of its location or structure • Chemical energy is potential energy available for release in a chemical reaction • Energy can be converted from one form to another Animation: Energy Concepts Copyright © 2008 Pearson Education, Inc., publishin ...
Metabolism of lipids
Metabolism of lipids

... II II R-C-CH2-C-S-CoA + CoA + CO2 • reduction with NADPH, etc. ...
6.2 Assimilation of inorganic nitrogen
6.2 Assimilation of inorganic nitrogen

...  Nitrogenase activity is inhibited by ammonia and under starvation conditions with a low EC.  Ammonia switch – quick and reversible inhibition by ammonia : Ammonia accumulation An arginine residue of azoferredoxin is bound with ADP-ribose from NAD+.  The nitrogenase complex is inactive with ADP- ...
Cellular Respiration WebQuest
Cellular Respiration WebQuest

... 3. THINK: ATP provides the body with energy. Give 3 examples of how ATP is used in organisms. ...
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... across a membrane • Voltage is created by differences in the distribution of positive and negative ions • ~ -50 to -200 mV (minus indicates that the inside of the cell is negative relative to the outside) → membrane potential favors the passive transport of cations into the cell and anions out of th ...
Oxygen and the Growth and Metabolism of
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... Eflects of changes in culture Eh During anaerobic growth of Clostridium acetobutylicum in the glucose +casein hydrolysate basal medium, the culture E h was in the range - 250 to - 400 mV. These reducing conditions were very rapidly established by the inoculum if the medium was first made anaerobic b ...
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... o AMP SynthesisAspartate serves as an amino donor to make adenosine monophosphate ( two steps: add the entire aspartate then cleave it off leaving the amino) o GMP synthesisIMP Dehydrogenase to make Xanthosine monopphospate and then glutamine is used as an amino group donor that replaces the carbo ...
chapter 1 introduction: themes in the study of life
chapter 1 introduction: themes in the study of life

... • Contains DNA that is segregated from the rest of the cell. DNA is organized with proteins into chromosomes that are located within the nucleus, the largest organelle of most cells. • Cytoplasm surrounds the nucleus and contains various organelles of different functions • Some cells have a tough ce ...
BE100a - Interchim
BE100a - Interchim

... Aerobic cellular respiration, a process requiring the use of oxygen, is the most efficient form of ATP production. ATP can also be produced anaerobically, without the presence of oxygen. Oxidative metabolism begins with the breakdown of organic nutrients such as carbohydrates, sugars, proteins, vita ...
A Strongly Inwardly Rectifying K+ Channel that Is Sensitive to ATP
A Strongly Inwardly Rectifying K+ Channel that Is Sensitive to ATP

... possibility of cloning ATP-sensitive inwardly rectifying Kt channels, and two cDNA clones have been reported to give rise to weakly rectifying K+ channels sensitive to ATP (Ashford et al., 1994; Inagaki et al., 1995). Here we report the cloning and expression of a strongly rectifying Kt channel from ...
modelling human energy conversion and metabolism
modelling human energy conversion and metabolism

... processes. For instance, tissue hypoxia may be caused by great exertion rather than by ischaemia or tumour growth. Other examples are dehydration, high body temperatures caused by exertion rather than fever, and high blood lactate levels caused by physical exertion rather than hypoxia or shock [1]. ...
Energy and Metabolism - McGraw Hill Higher Education
Energy and Metabolism - McGraw Hill Higher Education

... to convert matter from a more ordered, less stable form to a less ordered, but more stable form. For this reason, the second law is sometimes called “time’s arrow.” Looking at the photographs in figure 6.3, you could put the pictures into correct sequence using the information that time had elapsed ...
BIOCHEMISTRY NATIONAL BOARD EXAM REVIEW
BIOCHEMISTRY NATIONAL BOARD EXAM REVIEW

... The following questions (1-243) are from nine National Dental Board Examinations in Biochemistry-Physiology from 1978-1998. 1998 is the latest board exam released by the American Dental Association. This compilation of questions is intended to show the format, the subject areas generally covered, an ...
biochemistry national board exam review
biochemistry national board exam review

... The following questions (1-243) are from nine National Dental Board Examinations in Biochemistry-Physiology from 1978-1998. 1998 is the latest board exam released by the American Dental Association. This compilation of questions is intended to show the format, the subject areas generally covered, an ...
Gluconeogenesis Glycogen metabolism
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Chapter 4 PowerPoint
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... ALEK and phloem loading from the hollow petioles of adult Ricinus leaves (M BAKER, 1977). In our own laboratory l!TovaCmY and ULLRICH-EBERIUS found correlations between membrane potential and active glucose transport in fronds of the angiosperm water plant Lemna gibba (fig. 5). We have also -sucrose ...
Detoxikace endogenních a exogenních látek
Detoxikace endogenních a exogenních látek

...  in humans: ~60 isoenzymes; the most abundant: CYP3A4  monooxygenases: RH + O2 + NADPH + H+ ROH + H2O + NADP+  Electrons from NADPH+H+ are transferred to NADPHcytochrome P450 reductase, then to cytochrome P450 and to oxygen → one oxygen atom is inserted into the substrate  They metabolize not o ...
Metabolism
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... • Coenzyme that transfers hydrogen ions and electrons within cells. • Hydrogen atoms are frequently removed from nutrient substrates in bioenergetic pathways (along with their high energy electrons) • The Hydrogen atoms must be continuously picked up by the carrier molecules in order for glycolysis ...
Cfe Higher Biology Metabolism and Survival
Cfe Higher Biology Metabolism and Survival

... pass through the membrane, for example, a protein channel found in the plasma membrane allows chloride ions (Cl - ) to cross the membrane. • Carrier (pump) proteins - as the name suggests, carrier proteins bind to specific molecules or ions temporarily, enabling them to cross the membrane. This invo ...
Mitochondrial Functions in Mood Disorders
Mitochondrial Functions in Mood Disorders

... dative stress and/or altered calcium homeostasis [25]. An excess of glutamate in the synapse [26] leads to an excess of cytosolic calcium, which produces overactivity of calcium-depend‐ ent enzymes and an overload of mitochondria by calcium; it leads to cytoskeletal degrada‐ tion, protein malformati ...
Cfe Higher Biology Metabolism and Survival
Cfe Higher Biology Metabolism and Survival

... pass through the membrane, for example, a protein channel found in the plasma membrane allows chloride ions (Cl - ) to cross the membrane. • Carrier (pump) proteins - as the name suggests, carrier proteins bind to specific molecules or ions temporarily, enabling them to cross the membrane. This invo ...
Unit 2 - eduBuzz.org
Unit 2 - eduBuzz.org

... A catabolic reaction releases energy through the breakdown of a large molecule into smaller units (cellular respiration is a good example of this). An anabolic reaction uses energy to build small molecules into large ones, such as the synthesis of a protein from amino acids. Many of the pathways are ...
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Oxidative phosphorylation



Oxidative phosphorylation (or OXPHOS in short) is the metabolic pathway in which the mitochondria in cells use their structure, enzymes, and energy released by the oxidation of nutrients to reform ATP. Although the many forms of life on earth use a range of different nutrients, ATP is the molecule that supplies energy to metabolism. Almost all aerobic organisms carry out oxidative phosphorylation. This pathway is probably so pervasive because it is a highly efficient way of releasing energy, compared to alternative fermentation processes such as anaerobic glycolysis.During oxidative phosphorylation, electrons are transferred from electron donors to electron acceptors such as oxygen, in redox reactions. These redox reactions release energy, which is used to form ATP. In eukaryotes, these redox reactions are carried out by a series of protein complexes within the inner membrane of the cell's mitochondria, whereas, in prokaryotes, these proteins are located in the cells' intermembrane space. These linked sets of proteins are called electron transport chains. In eukaryotes, five main protein complexes are involved, whereas in prokaryotes many different enzymes are present, using a variety of electron donors and acceptors.The energy released by electrons flowing through this electron transport chain is used to transport protons across the inner mitochondrial membrane, in a process called electron transport. This generates potential energy in the form of a pH gradient and an electrical potential across this membrane. This store of energy is tapped by allowing protons to flow back across the membrane and down this gradient, through a large enzyme called ATP synthase; this process is known as chemiosmosis. This enzyme uses this energy to generate ATP from adenosine diphosphate (ADP), in a phosphorylation reaction. This reaction is driven by the proton flow, which forces the rotation of a part of the enzyme; the ATP synthase is a rotary mechanical motor.Although oxidative phosphorylation is a vital part of metabolism, it produces reactive oxygen species such as superoxide and hydrogen peroxide, which lead to propagation of free radicals, damaging cells and contributing to disease and, possibly, aging (senescence). The enzymes carrying out this metabolic pathway are also the target of many drugs and poisons that inhibit their activities.
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