Mechanism of the Inhibitory Action of Linoleic Acid on
... glycerol auxotroph of S. aureus suggested that free linoleic acid, rather than lipid containing this acid, inhibits growth. Linoleic acid probably inhibits growth by increasing the permeability of the bacterial membrane as a result of its surfactant action, and the presence of the PC plasmid increas ...
... glycerol auxotroph of S. aureus suggested that free linoleic acid, rather than lipid containing this acid, inhibits growth. Linoleic acid probably inhibits growth by increasing the permeability of the bacterial membrane as a result of its surfactant action, and the presence of the PC plasmid increas ...
Bile-Acid Sequestrants: Glucose-Lowering Mechanisms - HAL
... Even though no difference was found in the size of the total bile acid pool, the contribution of specific bile acid species to the pool was altered in T2D. Thus, the pool of the secondary bile acid DCA was elevated as was the DCA input rate, whereas the CDCA pool decreased [8]. The CA pool was unch ...
... Even though no difference was found in the size of the total bile acid pool, the contribution of specific bile acid species to the pool was altered in T2D. Thus, the pool of the secondary bile acid DCA was elevated as was the DCA input rate, whereas the CDCA pool decreased [8]. The CA pool was unch ...
Effect of Nicotinamide on Proliferation, Differentiation, and Energy
... Nicotinamide, the amide derivative of vitamin B3, is the precursor for the coenzyme nicotinamide adenine dinucleotide (NAD+). Nicotinamide is involved in a wide range of biological processes that include energy production; fatty acid, cholesterol, and steroid biosynthesis; signal transduction; and m ...
... Nicotinamide, the amide derivative of vitamin B3, is the precursor for the coenzyme nicotinamide adenine dinucleotide (NAD+). Nicotinamide is involved in a wide range of biological processes that include energy production; fatty acid, cholesterol, and steroid biosynthesis; signal transduction; and m ...
PRESCRIBING INFORMATION
... estriol determinations which use enzymatic hydrolysis are unaffected by formaldehyde. Formaldehyde causes falsely elevated 17-hydroxycorticosteroid levels when the Porter-Silber method is used and falsely decreases 5-hydroxy-indoleacetic acid (5H1AA) levels by inhibiting colour development when nitr ...
... estriol determinations which use enzymatic hydrolysis are unaffected by formaldehyde. Formaldehyde causes falsely elevated 17-hydroxycorticosteroid levels when the Porter-Silber method is used and falsely decreases 5-hydroxy-indoleacetic acid (5H1AA) levels by inhibiting colour development when nitr ...
J B , Mar. 2004, p. 1531–1536 Vol. 186, No. 5
... Materials. The crtE (GGDP synthase), crtB (phytoene synthase), and crtI (phytoene desaturase) genes are from Erwinia uredovora, as described elsewhere (21, 27). crtM (diapophytoene synthase) and crtN (diapophytoene desaturase) are from Staphylococcus aureus (25, 27). Bacillus stearothermophilus farn ...
... Materials. The crtE (GGDP synthase), crtB (phytoene synthase), and crtI (phytoene desaturase) genes are from Erwinia uredovora, as described elsewhere (21, 27). crtM (diapophytoene synthase) and crtN (diapophytoene desaturase) are from Staphylococcus aureus (25, 27). Bacillus stearothermophilus farn ...
Multi-Organ Contribution to the Metabolic Plasma Profile Using
... such as baseline correction, chromatogram alignment, time-window setting and multivariate curve resolution (MCR) [12] were performed using custom scripts. Automatic peak detection and mass spectrum deconvolution with ChromaTof software were performed using a peak width set to 2 s. For the identifica ...
... such as baseline correction, chromatogram alignment, time-window setting and multivariate curve resolution (MCR) [12] were performed using custom scripts. Automatic peak detection and mass spectrum deconvolution with ChromaTof software were performed using a peak width set to 2 s. For the identifica ...
Long-chain fatty acids increase basal metabolism
... LC fatty acids increase resting heat rate. The rate of heat production of small isolated cardiac muscle preparations, an indicator of basal metabolism, was measured at high resolution with a microcalorimetric technique. Figure 3 shows a representative example of the effect of oleate (C18:1) on resti ...
... LC fatty acids increase resting heat rate. The rate of heat production of small isolated cardiac muscle preparations, an indicator of basal metabolism, was measured at high resolution with a microcalorimetric technique. Figure 3 shows a representative example of the effect of oleate (C18:1) on resti ...
Lysine Inhibition of in vivo Homocitrate Synthesis in
... blue in 95 yoethanol. This indicator reveals acids as yellow spots on a blue background. By the combination of scanning and spraying, radioactive acids were detected. Homocitric lactone, citric acid, a-ketoglutaric acid and succinic acid were spotted as standards. For co-chromatography, the ether ex ...
... blue in 95 yoethanol. This indicator reveals acids as yellow spots on a blue background. By the combination of scanning and spraying, radioactive acids were detected. Homocitric lactone, citric acid, a-ketoglutaric acid and succinic acid were spotted as standards. For co-chromatography, the ether ex ...
Effect on cell surface hydrophobicity and susceptibility of
... studies have shown that the anti-microbial activity of these medicinal plants is too low to kill microbes or to inhibit their growth in animal tissues, their actions must be based on other mechanisms [20]. In this study, we have shown that CSH of H. pylori, as measured by SAT, can be modulated by me ...
... studies have shown that the anti-microbial activity of these medicinal plants is too low to kill microbes or to inhibit their growth in animal tissues, their actions must be based on other mechanisms [20]. In this study, we have shown that CSH of H. pylori, as measured by SAT, can be modulated by me ...
C 2 R
... 87 were compared. In most cases Phe87, was mutated to amino acids with small nonpolar side chains (Gly, Ala, Leu, Ile, Val), whereas only two uncharged polar amino acids (Ser, Tyr) were evaluated. Dependent on the substrate tested and the enzyme template, the type of mutation of Phe87 has differenti ...
... 87 were compared. In most cases Phe87, was mutated to amino acids with small nonpolar side chains (Gly, Ala, Leu, Ile, Val), whereas only two uncharged polar amino acids (Ser, Tyr) were evaluated. Dependent on the substrate tested and the enzyme template, the type of mutation of Phe87 has differenti ...
The Citric Acid Cycle
... There is no net conversion of acetate (also from fatty acids and amino acids) to any of the citric acid cycle intermediate, thus neither to carbohydrates. Net conversion of acetate to four-carbon citric acid cycle intermediates occurs via the glyoxylate cycle, occurring in plants, certain inverteb ...
... There is no net conversion of acetate (also from fatty acids and amino acids) to any of the citric acid cycle intermediate, thus neither to carbohydrates. Net conversion of acetate to four-carbon citric acid cycle intermediates occurs via the glyoxylate cycle, occurring in plants, certain inverteb ...
The outer frontier: the importance of lipid metabolism in the skin
... certain antimicrobial peptides and certain amphiphilic lipids, particularly sphingosine and free fatty acids, decrease the growth of microbes, thereby reducing infection (3). Acidification of the SC The low pH of the SC is an important contributor to antimicrobial defense. That the surface of the sk ...
... certain antimicrobial peptides and certain amphiphilic lipids, particularly sphingosine and free fatty acids, decrease the growth of microbes, thereby reducing infection (3). Acidification of the SC The low pH of the SC is an important contributor to antimicrobial defense. That the surface of the sk ...
Journal of Bacteriology
... sufficient to prevent lysis (Fig. 2). The Dalanyl-D-alanine adding enzyme of strain TKL-46 has a low activity in vitro, and it is temperature-sensitive (Fig. 3). The in vitro activity of the L-alanine adding enzyme of strain H-1119 at 30 C is about 5% of that of the wild type. We suppose that this a ...
... sufficient to prevent lysis (Fig. 2). The Dalanyl-D-alanine adding enzyme of strain TKL-46 has a low activity in vitro, and it is temperature-sensitive (Fig. 3). The in vitro activity of the L-alanine adding enzyme of strain H-1119 at 30 C is about 5% of that of the wild type. We suppose that this a ...
MORINGA OLEIFERA IN SILICO Research Article
... experimentation have been applied to therapeutic context and advanced tools have been harnessed to transform information about molecular mechanisms and targets into therapies directed against disease [6]. Targeted studies, which seek to understand the basic chemistry and physiology of a disease, see ...
... experimentation have been applied to therapeutic context and advanced tools have been harnessed to transform information about molecular mechanisms and targets into therapies directed against disease [6]. Targeted studies, which seek to understand the basic chemistry and physiology of a disease, see ...
Malo-ethanolic fermentation in Saccharomyces and
... been established and requires more in-depth physiological studies. In addition, the putative mae1p protein did not contain a N-terminal membrane-targeting signal, but the existence of an internal membrane signal motif was suggested (Grobler et al. 1995). Proton flux studies with Sch. pombe during L-m ...
... been established and requires more in-depth physiological studies. In addition, the putative mae1p protein did not contain a N-terminal membrane-targeting signal, but the existence of an internal membrane signal motif was suggested (Grobler et al. 1995). Proton flux studies with Sch. pombe during L-m ...
The Tricarboxylic Acid Cycle in Thiobacillus
... & Hoare (I 969) we were unable to detect the a-ketoglutarate dehydrogenase in Thiobacillus denitrijicans. We also failed to demonstrate this enzyme in cell-free extracts from Thiobacillus-A2 when grown autotrophically. Our results further indicate that the absence of a-ketoglutarate dehydrogenase ca ...
... & Hoare (I 969) we were unable to detect the a-ketoglutarate dehydrogenase in Thiobacillus denitrijicans. We also failed to demonstrate this enzyme in cell-free extracts from Thiobacillus-A2 when grown autotrophically. Our results further indicate that the absence of a-ketoglutarate dehydrogenase ca ...
initial rates for many enzymatic reactions exhibit bell
... -must only start measuring after lag period is completed but before [S] becomes limiting for the E under study -essential that the coupling E used never becomes rate-limiting so that the measured rate is always determined by the activity of the E under study -efficiency of coupling E will depend on ...
... -must only start measuring after lag period is completed but before [S] becomes limiting for the E under study -essential that the coupling E used never becomes rate-limiting so that the measured rate is always determined by the activity of the E under study -efficiency of coupling E will depend on ...
Determinants of blood pH in health and disease
... removed or destroyed. These principles may seem very basic indeed, but they are often overlooked in the analysis of clinical acid–base physiology, leading to incorrect conclusions. For example, a hyperchloremic metabolic acidosis can only be brought about in two ways. First, Cl– ions can be added to ...
... removed or destroyed. These principles may seem very basic indeed, but they are often overlooked in the analysis of clinical acid–base physiology, leading to incorrect conclusions. For example, a hyperchloremic metabolic acidosis can only be brought about in two ways. First, Cl– ions can be added to ...
Production of long chain alcohols and alkanes upon coexpression of
... † Electronic supplementary information (ESI) available: Supplementary Table S1. See DOI: 10.1039/c5mb00268k ...
... † Electronic supplementary information (ESI) available: Supplementary Table S1. See DOI: 10.1039/c5mb00268k ...
Relationship between Human Adipose Tissue Agouti and - Zen-Bio
... metabolism, may represent a peripheral mechanism for agouti in the development of obesity. Consistent with this, although transgenic mice expressing agouti only in adipose tissue did not become obese, hyperinsulinemia in these mice produced by either daily insulin injection (Mynatt et al. 1997) or s ...
... metabolism, may represent a peripheral mechanism for agouti in the development of obesity. Consistent with this, although transgenic mice expressing agouti only in adipose tissue did not become obese, hyperinsulinemia in these mice produced by either daily insulin injection (Mynatt et al. 1997) or s ...
Answers - U of L Class Index
... High levels of ketone bodies lead to ketosis, a condition characterized by acidosis (a drop in blood pH values), and characterized by excessive urination and strong thirst. Diabetics are unable to metabolize glucose and break down large amount of fats, which give high levels of acetyl CoA resulting ...
... High levels of ketone bodies lead to ketosis, a condition characterized by acidosis (a drop in blood pH values), and characterized by excessive urination and strong thirst. Diabetics are unable to metabolize glucose and break down large amount of fats, which give high levels of acetyl CoA resulting ...
AFLUID June 47/6 - AJP
... whereas aspartate in a concentration up to 10 mM did not have any effect. With all AA except Arg and Asp a significant increase in Gm was observed, with a peak increase ranging from 7 6 4 (Phe, 50 mM) to 65 6 25% (Ala, 1 mM). The maximal depolarization and conductance increase obtained with differen ...
... whereas aspartate in a concentration up to 10 mM did not have any effect. With all AA except Arg and Asp a significant increase in Gm was observed, with a peak increase ranging from 7 6 4 (Phe, 50 mM) to 65 6 25% (Ala, 1 mM). The maximal depolarization and conductance increase obtained with differen ...
Sample pages 1 PDF
... enteropeptidase is necessary to start the reaction. This activation mechanism is common for most serine proteases and serves to prevent autodigestion of the pancreas. ...
... enteropeptidase is necessary to start the reaction. This activation mechanism is common for most serine proteases and serves to prevent autodigestion of the pancreas. ...
Intestinal Protein digestion in vitro Assay
... • CNCPS feed library has a set digestibility for the Protein B1 and B2 fractions (formerly B2 and B3 fractions) • Some changes in nomenclature have occurred: we abandon the use of Trichloroacetic acid or Tungstic acid precipitation for describing NPN and Soluble true protein in the feed library. • T ...
... • CNCPS feed library has a set digestibility for the Protein B1 and B2 fractions (formerly B2 and B3 fractions) • Some changes in nomenclature have occurred: we abandon the use of Trichloroacetic acid or Tungstic acid precipitation for describing NPN and Soluble true protein in the feed library. • T ...