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Smooth endoplasmic reticulum
Smooth endoplasmic reticulum

... The replenishment of OAA in the TCA cycle under these conditions is by the carboxylation of pyruvate with CO2 in a reaction catalyzed by the enzyme pyruvate carboxylase. This is an energy-requiring reaction which is driven by ATP hydrolysis. Pyruvate carboxylase is located in the mitochondrial matri ...
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... 33. You are treating a patient who exhibits extreme sensitivity to UV light. You supect a form of xeroderma pigmentosa. You ask about any other incidences of light sensitivity in the family, and learn that this is the first incident observed. Which of the following statements is TRUE? A. The trait m ...
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... 12. Role of Cobalamin in Amino Acid Catabolism Pernicious anemia is caused by impaired absorption of vitamin B12. What is the effect of this impairment on the catabolism of amino acids? Are all amino acids equally affected? (Hint: see Box 17–2.) Answer The catabolism of the carbon skeletons of valin ...
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... and betaine containing compounds [13,14] have also been found in wild fungi. Many biological active enzymes [15], including peroxidases [16], haloperoxidases [17], and others [18] have been isolated from different fungi and used in the chemical science and industry [19]. Mushrooms are the fungi that ...
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... III. De Novo Synthesis of Fatty Acids • A large proportion of the fatty acids used by the body is supplied by the diet. • Carbohydrates, protein, and other molecules obtained from the diet in excess of the body's needs for these compounds can be converted to fatty acids, which are stored as triacyl ...
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... Once absorbed into body, can be stored temporarily as triglycerides or split into glycerol and three fatty acids which then are catabolized -->energy released by enzymatic breakage of bonds --> some work done and the rest lost as heat ...
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Ketosis



Ketosis /kɨˈtoʊsɨs/ is a metabolic state where most of the body's energy supply comes from ketone bodies in the blood, in contrast to a state of glycolysis where blood glucose provides most of the energy. It is characterised by serum concentrations of ketone bodies over 0.5 millimolar, with low and stable levels of insulin and blood glucose. It is almost always generalized with hyperketonemia, that is, an elevated level of ketone bodies in the blood throughout the body. Ketone bodies are formed by ketogenesis when liver glycogen stores are depleted (or from metabolising medium-chain triglycerides). The main ketone bodies used for energy are acetoacetate and β-hydroxybutyrate, and the levels of ketone bodies are regulated mainly by insulin and glucagon. Most cells in the body can use both glucose and ketone bodies for fuel, and during ketosis, free fatty acids and glucose synthesis (gluconeogenesis) fuel the remainder.Longer-term ketosis may result from fasting or staying on a low-carbohydrate diet, and deliberately induced ketosis serves as a medical intervention for intractable epilepsy. In glycolysis, higher levels of insulin promote storage of body fat and block release of fat from adipose tissues, while in ketosis, fat reserves are readily released and consumed. For this reason, ketosis is sometimes referred to as the body's ""fat burning"" mode.
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