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Practice Exam for Semester 2, Part II Final Exam NOTE: these are just a selection of questions related to the topics covered in Semester 2. The format on your final will be different and is not limited to the topics in these questions alone. To study for the Semester 2, Part II final you should also review your previous exams as well as the vocab cards. 14) What is the appropriate order of blood flow in a human? a) left atrium, left ventricle, pulmonary artery, pulmonary vein, right ventricle, right atrium b) right atrium, right ventricle, pulmonary artery, pulmonary vein, left atrium, left ventricle c) left ventricle, left atrium, pulmonary vein, pulmonary artery, right atrium, right ventricle d) right atrium, right ventricle, pulmonary vein, pulmonary artery, left ventricle, left atrium 15) Oxygen must be delivered efficiently for cellular respiration to occur. There are several means by which organisms have evolved to allow this to occur. One example of efficient oxygen uptake is counter-current exchange in the gills of fish. The following diagram shows this: a) What letter represents blood that has the HIGHEST amount of oxygen? ____ b) What letter represents water that has the HIGHEST amount of oxygen? ____ Another way in which oxygen uptake can be maximized is how hemoglobin changes structure in response to the environmental conditions. Suppose you have the following data: Partial Pressure of O2 (mm Hg) 10 30 40 55 70 Number of oxygens carried 0 1 2 3 4 c) Draw a graph on the right that shows the binding capabilities of hemoglobin. Be sure to label each axis properly. Label the curve "normal". d) pH can also affect hemoglobin binding. Why would this be important to an organism (especially related to oxygen delivery) for the pH to change hemoglobin binding capabilities? _____________ ________________________________________________________________________________ e) On the graph, draw where you would expect to find hemoglobin that has been exposed to an acidic environment. Label the curve "acidic". f) Describe another method (or structure) by which an animal will maximize the amount of oxygen that their respiratory systems can take up? _____________________________________________ ________________________________________________________________________________ 16) Insulin released from the pancreas will have all the following effects on the body (circle the appropriate level for each statement) a) INCREASE or DECREASE in glycogen formation b) INCREASE or DECREASE in blood sugar levels 17) Land animals convert ammonia to either uric acid or urea. This requires energy. What are two reasons that this is advantageous to a land animal (despite being energetically expensive)? 1-_______________________________________________________________________________ _________________________________________________________________________________ 2-_______________________________________________________________________________ _________________________________________________________________________________ 18) The human kidney's function is to produce concentrated urine. The kidney is made up of approximately one million nephrons to help this occur. A diagram of a nephron is below. a) On the diagram, circle where the concentration of salt in the extracellular environment will be HIGHEST. b) On the diagram write "ADH" where you will find a large amount of ADH receptors. c) Alcohol will inhibit ADH receptors. Will this cause an INCREASE or DECREASE in water reabsorption by the kidney. 1) The diagram to the right shows one part of the photosynthesis reactions. a) How many PGAL molecules does it take to construct one glucose? ____ b) Would the reaction of NADPH -> NADP+ + H+ be EXOTHERMIC or ENDOTHERMIC? c) Explain your answer to (b) ___________ ____________________________________ ____________________________________ d) If you made only the reactions of the Calvin Cycle in a test tube with an unlimited amount of ATP and NADPH, would you expect to see any production of oxygen? YES or NO e) Explain your answer to (d) ____________ _____________________________________ _____________________________________ 2) Rubisco is known to grab oxygen, rather than carbon dioxide in a reaction known as photorespiration. This is inefficient for the cell. Some plants have adapted mechanisms to prevent photorespiration. A diagram of this adaptation is below: a) Mark an "X" where you would find the enzyme Rubisco. b) If the Bundle-sheath cell is not permeable to oxygen or carbon dioxide, then how does the carbon dioxide get into the bundle-sheath cell? __________ ___________________________________________ ___________________________________________ c) If a plant had the cells seen to the right, would you expect to see a stomates open during the day? YES or NO d) Explain your answer to (c) __________________ ___________________________________________ 3) You are off to your first prom date with a bouquet of flowers. Your mom had the flowers in water until just before you left. You take them out of the water, and put them in the car. About 30 minutes later, you arrive to pick up your date and give your date the flowers, who goes ahead and puts them in water. After the dance, your date looks at the flowers and they have wilted. Explain why the flowers have wilted, even though your date put them in water. _________________________________________________________ _______________________________________________________________________________________ _______________________________________________________________________________________ 4) Explain why water is necessary for sugar transport to occur effectively in a plant. __________________ _______________________________________________________________________________________ _______________________________________________________________________________________ 5) The diagram to the right shows the evolution of plants over the past 500 million years. a) What is more closely related to a conifer: A FLOWERING PLANT or A FERN b) What are two specific advantages that vascular plants have that nonvascular plants don't have? 1-____________________________ ______________________________ 2-____________________________ ______________________________ c) On the diagram, add two lines to show how monocots and dicots fit into this phylogeny. 6) The diagram to the right is the life cycle of a fern. a) Match the capital letters in the diagram to each of following three processes: FERTILIZATION, MEIOSIS, MITOSIS. A_____________ B_____________ C_____________ b) Is the zygote considered HAPLOID or DIPLOID? c) Circle one of the diagrams that represent a SPOROPHYTE. d) Put a square around one of the diagrams that represent a GAMETOPHYTE. e) If the diploid cell has 44 chromosomes, then how many chromosomes does the egg in this diagram have? ______ 7) A research team led by Dr. I.M. Sealy recently discovered the drug Caltizar. Caltizar causes Calcium Ion Channels to open permanently. A biology grad student isolates some giant squid neurons to study Caltizar. Upon adding the Caltizar to the neurons, the grad student notices that the neuron intially causes the next neuron to fire. a) Explain why the drug causes the next neuron to fire. ___________________________________ ________________________________________________________________________________ b) After this initial firing, the giant squid neuron no longer causes the next neuron to fire. Explain why this might be. _________________________________________________________________ _________________________________________________________________________________ 8) Researchers are trying to understand the molecular mechanisms of how memory works. One hypothesis is that an enzyme crosses the synapse from the postsynaptic neuron to the presynaptic neuron. This enzyme may cause potassium channels to close in the presynaptic neuron. a) Would the closure of potassium channels in the axon terminal INCREASE or DECREASE the amount of Ca2+ entering the axon terminal when an action potential is received. ________________ b) Explain your answer to (a) ________________________________________________________ ________________________________________________________________________________ 9) As a neurologist, you observe several patients with abnormal muscle tissues or synapses. For each of the scenarios, please answer the predicted result (compared to a normal patient) a) A patient with a wider than normal synapse between the motor neuron and muscle cell membrane. -Would this patient have muscle contractions that are SLOWER, NORMAL, or FASTER (circle one) -Explain your answer _______________________________________________________________ _________________________________________________________________________________ b) A patient has a troponin complex that is mutated so that when bound to Ca2+, it doesn't move tropomyosin. -Would this patient have muscle contractions that are SLOWER, NORMAL, or FASTER (circle one) -Explain your answer _______________________________________________________________ _________________________________________________________________________________ 10) Which order is appropriate for a portion of the path of sperm in a male? a) prostate gland, vas deferens, urethra c) testicle, bladder, seminal vesicle b) testicle, vas deferens, urethra d) scrotum, testicle, oviduct 11) Which order do developmental stages proceed in? a) cleavage, gastrulation, organogenesis b) gastrulation, cleavage, organogenesis c) cleavage, organogenesis, gastrulation d) gastrulation, organogenesis, cleavage 12) When a woman becomes pregnant, her body receives the proper hormonal signals to maintain the proper environment for the embryo. Which of the following does NOT occur when a woman becomes pregnant? a) a surge of LH and FSH causes ovulation to occur b) the corpus luteum is maintained and continues to produce progesterone c) the endometrium remains thick d) HCG is released by the embryo 13) You take a sample of mesoderm tissue from a developing frog embryo to study it. Which of the following is NOT a tissue or organ that develops from mesoderm? a) cardiac muscle c) skin b) bones d) blood 19) Interferon is a part of your non-specific immune system. It prevents the replication of viral DNA and protein. The specific immune system will also respond to a viral infection. For each of the following statements, state where it is part of the HUMORAL (H) response, or the CELL MEDIATED (C) response or BOTH (B) ___ Involves MHC molecules ___ Involves Antibodies ___ Macrophages consume antigen ___ Killer T cells secrete perforin ___ Memory B cells are made ___ Involves antigens 20) Below is a chart showing the immune response compared to time. Please draw in the two lines to show how the immune response would compare between the first exposure to a certain antigen, to the second exposure to that same antigen. Immune Response First Exposure Second Exposure 21) Aspirin inhibits the action of platelets. Because of this, individuals who are about to undergo surgery are advised against taking any aspirin. Which of the following will be most likely to occur if a surgery patient takes aspirin? a) blood vessels become weaker and will break more easily b) blood will not be able to clot properly c) blood will become thicker and flow slower d) blood pressure increases QUESTION 7 You are studying the cellular respiration in a mouse cell. Using the diagram below, answer the following questions. 7a) What is the net yield of ATP per glucose in glycolysis? _______ 7b) Suppose an inhibitor for the enzyme that catalyzes Step 5 is added. This inhibitor binds to location remote from the active site. What kind of inhibitor is this-- competitive or noncompetitive? ________________ 7c) What molecule will build up as a result of this inhibitor? __________________________ 7d) Suppose a cell is depleted of oxygen. What metabolic process will it begin after glycolysis? ______________ ____________________________________________ 7e)What is the purpose of this pathway? ___________ ___________________________________________ 7f) Is the cell in this problem a prokaryotic cell or a eukaryotic cell? _____________________________ 7g) What are two differences between prokaryotes and eukaryotes. _________________________________ ___________________________________________ QUESTION 8 DNP (Dinitrophenol) causes pores to form in the membrane of the mitochondria. 8a) What effect (if any) would this have on ATP production? Explain your answer. _________________________ ____________________________________________________________________________________________ ____________________________________________________________________________________________ 8b) What effect (if any) would adding DNP have on oxygen usage by the cell (the most immediate effect)? _______________________________________________________________________________________________ _______________________________________________________________________________________________ 8c) You discover a new drug called "Blockaid". Blockaid binds to the "stalk" of ATP synthase to prevent protons from passing through. If you add Blockaid to a cell, what would the effect (in any) on ATP production be? Explain your answer. ________________________________________________________________________________________ _______________________________________________________________________________________________ QUESTION 9 Cellular respiration is necessary for cells to survive. The following diagram shows one of the parts of this process. 9a) This diagram shows: (circle one) A) Glycolysis B) Citric Acid Cycle C) Fermentation D) Pyruvate Oxidation 9b) Suppose there was a mutation in the enzyme "fumarase", causing it to become nonfunctional. What molecule would build up in the cell? ________ 9c) Could a cell that had this mutation still produce any ATP? Circle One Yes or No 9d) Explain your answer to (c) _______________________________________________________________________________________________ _______________________________________________________________________________________________ The next two diagrams show oxidative phosphorylation (also known as the electron transport chain). 9e) In an active cell, where would you find a HIGHER pH? (circle one) A) Inner Membrane Space B) Matrix 9f) Explain your answer to (e) _______________________________________________________________________________________________ _______________________________________________________________________________________________ Cyanide binds to and inhibits Cytochrome a3 (labeled cyt a3) in the right diagram above. Suppose your cells have been poisoned by cyanide. 9g) 10 minutes after poisoning, would you expect the levels of ATP to be HIGHER or LOWER than cells that haven't been poisoned. ________________________ 9h) Explain your answer to (g) _____________________________________________________________________ _______________________________________________________________________________________________ 9i) 10 minutes after poisoning, would you expect the levels of NADH to be HIGHER or LOWER than cells that haven't been poisoned. _______________________ j) Explain your answer to (i) _______________________________________________________________________________________________ _______________________________________________________________________________________________ k) Name one difference between cellular respiration of prokaryotes and eukaryotes. ___________________________ _______________________________________________________________________________________________ l) A yeast cell may produce ATP by which of the following methods: (check all that apply) ___ Glycolysis ___ Alcoholic Fermentation ___ Lactic Acid Fermentation ___ Cellular Respiration m) Why does a cell breakdown sugar using multiple steps? (why doesn't it breakdown the sugar in just one big step?) ______________________________________________________________________________________________ ______________________________________________________________________________________________