Download Cardiff International School Dhaka (CISD) Lost Class Make Up

Cardiff International School Dhaka (CISD)
Lost Class Make Up Assignment
Class: A2/A3
Subject: Chemistry
Date: 22nd (Sunday)-28th (Saturday) March 2015
Total Mark- 20
Instructions: All of your assignment must be done in A4 size paper. Mention your Name,
Class, Roll and Section clearly on the top sheet of your assignment.
Submission Deadline: Saturday 28th March 10.00 AM to the respective subject teacher. The
deadline is strict.
Name:.................................................................................................................................................
Class: .........................Roll: ........................ Sec: .................. Teacher: ......................................
Sunday-Saturday
22-28 March 2015
Lesson:
28.8 Genetic Mutations
Task:
Study –
i. Explanation of genetic mutations
ii. Sickle-cell anaemia
iii. Cystic fibrosis
iv. Modification of protein structure
Worksheet/Exercise:
Q1. Three levels of protein structure are primary, secondary and tertiary.
a) Describe the primary structure of a typical protein containing one polypeptide chain.
Name the type of chemical bonding involved in the primary structure of a protein.
[4]
b) Name 2 types of protein secondary structure. For each type give a named example and its
location in the cell.
Describe the bonding that stabilizes these secondary structures.
[8]
c) Describe four different types of interactions that maintain the tertiary structure of a
protein.
For each type of interaction give an explanation how the attractive forces arise.
[8]
Text Book/Reference Book:
Chemistry Coursebook, Page No. 430 - 432, Chapter – 28
Answer Keys:
Q1. a) The primary structure of a protein is the level of protein structure which refers to the
specific sequence of amino acids. When two amino acids are in such a position that the
carboxyl groups of each amino acid are adjacent to each other, they can be combined by
undergoing a dehydration reaction which results in the formation of a peptide bond. Amino
acids in a polypeptide (protein) are linked by peptide bonds that begin with the N-terminal
with a free amino group and ends at C-terminal with a free carboxyl group.
Chemical bonding involved are covalent bonds such as peptide bonds, which are made during
the process of protein biosynthesis or translation.
b) α-helix and β-pleated sheet structure
c) Disulphide bridges, weak van der Waal’s forces, relatively weak hydrogen bonds, ionic
bonds
Help Lines:
For any assistance, please contact
Chemistry Teacher:
Jobaida Akther, [email protected]
Principal Head of School: G.M.Nizam Uddin, +88-01622181818, [email protected]