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BIOCHEMISTRY WEBQUEST Name: Date: Period: BASIC CHEMISTRY Link to find answers to #1 – 4, below: https://b51ab7d9e5e1e7063dcb70cee5c33cf7f4b7bad8.googledrive.com/host/0Bx6hk6AUBHxDc2d4 TDJZTFIyMGs/files/Bio%20101/Bio%20101%20Lectures/Organic%20and%20Biochemistry/Organic%2 0and%20Biochemistry-%20BIO%20101.htm 1. (a) Draw 2 separate carbon atoms both with four single bonds connected to hydrogen atoms (methane, CH4). (b) Next take away two hydrogens from each and draw the carbons connected together with a double bond. 2pts 2. What is the similarity between ionized and polar molecules? 2pts 3. What is the difference between hydrophilic and hydrophobic molecules? 2pts 4. Compare Macromolecules (polymers) to Monomers; complete the chart below 4pts Example of a Macromolecule Corresponding Monomer polysaccharide glycerol, fatty acid protein nucleic acid 1 BIOCHEMISTRY WEBQUEST Name: CARBOHYDRATES Date: Period: Link to find answers to #1 – 3, below: http://www2.nl.edu/jste/carbohyd.htm#dehydration%20synthesis 1. 6pts List the three main groups of carbohydrates and give a specific example of each type. 2. 3pts Play the animation of dehydration synthesis (the yellow box under “Disaccharides” heading). (a) What two monosaccharides did you start with? (b) What disaccharide was produced? (c) What molecule was released as a byproduct? 3. 6pts Four specific examples of polysaccharides are mentioned on this page. (a) Name them. (b) Which two are found in animals but not in plants? 2 BIOCHEMISTRY WEBQUEST Name: Date: Period: LIPIDS Link to find answers to #1 – 3, below: htt://www2.nl.edu/jste/lipids.htm Neutral Fats: 1. Based on what you can see in their structure, why do you suppose these molecules are known as “triglycerides”? (hint: what does “tri-“ mean? What do they have three of?) 1 pt 2. Play the animation (yellow box) of 3 fatty acids being attached to a glycerol backbone by dehydration synthesis. 2pts (a) What is the name of the functional group on the ends of fatty acids that lose their “–OH” in order to bond to the glycerol? (b) When making one triglyceride, how many molecules of water are formed? 2. (a) What is the (chemical/structural) difference between saturated and unsaturated fatty acids? 2pts (b) Which one has double bonds between carbon atoms? 1 pt 3. Phospholipids are similar to triglycerides in structure with one important difference. Instead of glycerol being attached to three fatty acids (as in triglycerides), in phospholipids there are ____ fatty acids and one ________ group. 2pts 3 BIOCHEMISTRY WEBQUEST Name: Date: Period: Phospholipids and the Cell Membrane: Link to answer questions (a) thru (d) below: http://www.uic.edu/classes/bios/bios100/lectures/membranes01.htm 1. You will need your headphones or ear buds to listen to the narration of this animation. Play the animation of phospholipids being immersed in water, and answer the following questions. 4 pts (a) What does “amphipathic” mean? (b) Why do the fatty acid “tails” always point away from water? (c) Why do the phosphate “heads” touch the water? (d) What is a “bilayer”? Link to answer the question below: http://www.susanahalpine.com/anim/Life/memb.htm 1. Click through the animation of cell membrane structure. In addition to phospholipids, what are three other materials also found in the cell membrane? 3pts Steroids. Cholesterol example Link to find answers to #1 – 3, below: http://www.wiley.com/legacy/college/boyer/0470003790/animations/cholesterol/cholesterol.htm 1. 3 pts View the “overview” button on this link. List three foods in which cholesterol is found. 2. 1 pt Click “Next”. SKETCH the diagram of a steroid here: 4 BIOCHEMISTRY WEBQUEST Name: Date: Period: 3. 4 pts Click “Next”. Besides its role in the cause of heart disease, list four vital roles of cholesterol in the body. 4. View the “Heart Injury” button on this page. Work through the links at the bottom to answer parts (a) thru (d) below. 8 pts (a) List two reasons why bad cholesterol (LDL) can elevate in a person. (b) Hypercholesterolemia. Why can’t a person remove LDL from the blood when they are genetically predisposed? (c) Briefly describe how high LDL cholesterol can lead to heart injury. (d) Name one drug that lowers blood cholesterol levels. Lipids: Fats, Oils and Waxes Link to find answers to #1 – 3, below: http://biology.clc.uc.edu/courses/bio104/lipids.htm 1. Read the story of the monarch butterfly. Why are lipids vital to it? 2pts 2. What do all lipids have in common? 1 pt 5 BIOCHEMISTRY WEBQUEST Name: Date: Period: 3. Saturated –v-s Unsaturated fats. Choose between these to answer (a) thru (c) below. 3 pts (a) Which type has double bonds between the carbon atoms, and fewer hydrogens bonded? (b) Which type is found mainly in animals/animal products? (c) Which type is liquid at room temperature? PROTEINS Link to find answers to #1 – 4, below: http://www2.nl.edu/jste/proteins.htm 1. Proteins are polymers of linked monomers called ___________ ___________. 1pt 2. Click on the “play” button (yellow box) to link the 2 amino acids in the diagram. (a) What kind of a bond is formed? 1 pt (b) What kind of chemical reaction creates this bond? 1 pt 3. List seven functions of proteins given on the page. 7pts 4. Proteins can be small or large. Larger proteins are folded into intricate shapes. (a) List their four levels of structure. 4pts (b) What level of folding determines the final shape of a molecule of hemoglobin? 1 pt 6 BIOCHEMISTRY WEBQUEST Name: Date: Period: 5. Proteins are held in their intricately folded shape by hydrogen bonds. These bonds can be disrupted when heated or treated with acids or salts. This is called “denaturation” and results in proteins losing their form. Go to this link http://www.sumanasinc.com/webcontent/anisamples/nonmajorsbiology/proteinstructure.html and work your way through the animation. What food/protein is being denatured in thus example? 1 pt NUCLEIC ACIDS Link to find answers to #1 – 6, below: http://science.howstuffworks.com/life/cellular-microscopic/dna1.htm 1. DNA (and RNA) are both polymers (large molecules) made up of what smaller monomers (building blocks)? 1 pt 2. Name the three parts of a nucleotide. 3pts 3. Where (in the cell) is DNA located? 1pt 4. Complete this statement: “DNA guides the cell (along with RNA) in making new _______________ that determine all of our biological traits.” 1 pt 4. What does “DNA” stand for (Google it if you have to)? 1pt 5. What are the names of the four different DNA bases? 4pts 6. DNA molecules are made of two connected strands of nucleotides that are twisted together like a spiral staircase, called a ____________________ ____________________. 1 pt 7