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Transcript
LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – BIO TECHNOLOGY
FIRST SEMESTER – NOVEMBER 2007
AE 16
BT 1814 - BIOMOLECULES
Date : 27/10/2007
Time : 1:00 - 4:00
Dept. No.
Max. : 100 Marks
PART - A
Answer all the Questions
I.
Choose the best answer :
1.
All the following sugar are interconvertible except
a) Glucose
b) galactose c) Mannose d) fructose
2.
Purine metabolise to form
a) urea b) ammonia c) uric acid
(20 Marks)
(5 x 1 = 5)
d) all the above
3.
Depot fat in mammalian cells principally comprises
a) cholesterol
b) cholesterol ester c) cerebroside d) Triacyl glycerol
4.
Non protein part of any enzyme is called
a) apoenzyme
b) epienzyme
c) coenzyme
5.
Hemoglobin is a
a) dimeric protein
protein
b) tetrameric protein
d) holoenzyme
c) trimeric protein d) monomeric
II.
State True or False, if False, state the reason
6.
7.
8.
9.
10.
Xanthine oxidase oxidizes, hypoxanthine to xanthine.
FAD is a nucleotide coenzyme
Multiple forms of enzymes catalyzing the same reaction are isoenzymes.
Glycogen is composed of β glycosidic bonds.
Plasmalogens contain an enol ether linkage at C2 position.
III.
Complete the following
11.
12.
13.
14.
15.
(5 x 1 = 5)
(5 x 1 = 5)
The α and β cyclic forms of D glucose are referred to as__________
The charged amino acid, which is electrically neutral, is called _________.
_________ is the specific region on the enzyme at which substrate binds.
_________ is the ring system present in cholesterol.
Nitrogenous bases are conjugated to pentose sugars by_________ linkage.
1
IV. Answer the following, each within 50 words
16.
17.
18.
19.
20.
(5 x 1 = 5)
Why is sucrose called non-reducing sugar?
Define Turnover number of an enzyme.
Write the structure of d GTP
What are essential fatty acids ?
What are non protein amino acids ?
PART - B
Answer any 5 questions each within in 350 words only
21.
22.
23.
24.
25.
26.
27.
28.
(5 x 8 = 40)
Derive Michalis Menten equation and mention the significance of Km value.
Explain the properties of fatty acids.
Discuss the syntheis and degradation of triacylglycerol
Discuss the biosynthesis of pyrimidine bases
Explain the classification of amino acid with the structure.
Write the structure for
i) NAD+
ii) Lactose
iii) Cholesterol
Give an account on Mucopolysaccharides
Write an account on Phospholipids
PART - C
Answer each of the following, within 1500 words
29.
Discuss the secondary structure of proteins ? Mention the forces responsible for
the maintenance of structure of protein
OR
Explain in detail the properties of monosaccharides
30.
Write elaborately the denovo synthesis of fatty acid
OR
Describe the IUB system of classification of enzymes.
(2 x 20 = 40)
*******************
2