Episodic memory, amnesia, and the hippocampal–anterior thalamic
... Markowitsch 1994), and biases can be introduced by the reliance on one particular research method. For these reasons we have tried, wherever possible, to present complementary data from an array of techniques and from more than one species. 2. Main features of the proposed model 1. The anatomical fo ...
... Markowitsch 1994), and biases can be introduced by the reliance on one particular research method. For these reasons we have tried, wherever possible, to present complementary data from an array of techniques and from more than one species. 2. Main features of the proposed model 1. The anatomical fo ...
Essentials in the neuronal organization of the CNS
... central nervous system. It is important to see clearly, however, that this handout does not substitute for the textbooks, but it can be used best in combination with the texts and the illustrations found in them. It will be important to read the Glossary on the first few pages to become familiar wit ...
... central nervous system. It is important to see clearly, however, that this handout does not substitute for the textbooks, but it can be used best in combination with the texts and the illustrations found in them. It will be important to read the Glossary on the first few pages to become familiar wit ...
Laminar Selectivity of the Cholinergic Suppression of Synaptic
... the strength of each synapse in stratum lacunosum-moleculare from neuron j in entorhinal cortex to neuron i in region CAl, as shown in Figure 2. R,, represents the strength of each synapse in stratum radiatum from neuron k in region CA3 to neuron i in region CAl. For clarity in the examples showing ...
... the strength of each synapse in stratum lacunosum-moleculare from neuron j in entorhinal cortex to neuron i in region CAl, as shown in Figure 2. R,, represents the strength of each synapse in stratum radiatum from neuron k in region CA3 to neuron i in region CAl. For clarity in the examples showing ...
The Matrix Protein Hikaru genki Localizes to Cholinergic Synaptic
... al., 2010). In most microglomeruli, a discrete pattern of Hig staining was observed in the surrounding regions of ChATpositive projection neuron axon terminals (Fig. 1I). These immunohistochemical data from antennal lobe, MB, and other brain regions, including the optic lobes (see Fig. 3 A, B), indi ...
... al., 2010). In most microglomeruli, a discrete pattern of Hig staining was observed in the surrounding regions of ChATpositive projection neuron axon terminals (Fig. 1I). These immunohistochemical data from antennal lobe, MB, and other brain regions, including the optic lobes (see Fig. 3 A, B), indi ...
Contrasting Effects of Reward Expectation on Sensory and Motor
... Irwin, 1999). Patients with damage to the LPFC show a tendency to neglect goals even though the task requirement is understood and remembered (Duncan et al., 1996; Manes et al., 2002). Recent human imaging studies show that the LPFC appears to be an important region for integrating motivation with c ...
... Irwin, 1999). Patients with damage to the LPFC show a tendency to neglect goals even though the task requirement is understood and remembered (Duncan et al., 1996; Manes et al., 2002). Recent human imaging studies show that the LPFC appears to be an important region for integrating motivation with c ...
Magel2 Is Required for Leptin-Mediated Depolarization of POMC
... Prader-Willi Syndrome is the most common syndromic form of human obesity and is caused by the loss of function of several genes, including MAGEL2. Mice lacking Magel2 display increased weight gain with excess adiposity and other defects suggestive of hypothalamic deficiency. We demonstrate Magel2-nu ...
... Prader-Willi Syndrome is the most common syndromic form of human obesity and is caused by the loss of function of several genes, including MAGEL2. Mice lacking Magel2 display increased weight gain with excess adiposity and other defects suggestive of hypothalamic deficiency. We demonstrate Magel2-nu ...
Protracted Synaptogenesis after Activity
... activated synapses, LTP induction was shown to lead to a transient increase in perforated synapses followed by a persistent increase in the frequency of boutons forming synapses with more than one spine, suggesting that LTP is associated with the formation of new synapses (Toni et al., 1999). Althou ...
... activated synapses, LTP induction was shown to lead to a transient increase in perforated synapses followed by a persistent increase in the frequency of boutons forming synapses with more than one spine, suggesting that LTP is associated with the formation of new synapses (Toni et al., 1999). Althou ...
Apparent Loss and Hypertrophy of Interneurons in a Mouse Model
... In contrast, even in aged mutant mice, many hippocampal interneurons retained staining for glutamic acid decarboxylase. Treatment with insulin-like growth factor-1 partially restored interneuronal number and reduced hypertrophy in some subregions. These results provide the first evidence for the inv ...
... In contrast, even in aged mutant mice, many hippocampal interneurons retained staining for glutamic acid decarboxylase. Treatment with insulin-like growth factor-1 partially restored interneuronal number and reduced hypertrophy in some subregions. These results provide the first evidence for the inv ...
Involvement of GABAergic and cholinergic medial septal neurons in
... various phenomena, including attention and acquisition of sensory information. Two types of HPC (types I and II) exist based on pharmacological, behavioral, and electrophysiological characteristics. Both types occur during locomotion, whereas only type II (atropine-sensitive) is present under ureth ...
... various phenomena, including attention and acquisition of sensory information. Two types of HPC (types I and II) exist based on pharmacological, behavioral, and electrophysiological characteristics. Both types occur during locomotion, whereas only type II (atropine-sensitive) is present under ureth ...
Program
and
Abstracts
from
the
Fifth
Annual
Canadian
Neuroscience
Meeting
May
29
–
June
1
2011
Quebec
City
Convention
Center
... synapses (P26‐40) due to the synaptic incorporation of the α5 subunit of the GABAA receptor (a5‐ GABAARs). Moreover, this age‐dependent synaptic expression of a5‐GABAARs was directly associated with the emergence of long‐term potentiation at IN inhibitory synapses. Finally, the slower time course ...
... synapses (P26‐40) due to the synaptic incorporation of the α5 subunit of the GABAA receptor (a5‐ GABAARs). Moreover, this age‐dependent synaptic expression of a5‐GABAARs was directly associated with the emergence of long‐term potentiation at IN inhibitory synapses. Finally, the slower time course ...
Cross-modal Circuitry Between Auditory and
... somatosensory receptive field. During combined sensory presentations, the onsets of the stimuli were adjusted to compensate for the differences in the average latency of auditory and somatosensory responses in AES cortex [somatosensory evoked responses ∼15 ms later than auditory (Wallace et al., 199 ...
... somatosensory receptive field. During combined sensory presentations, the onsets of the stimuli were adjusted to compensate for the differences in the average latency of auditory and somatosensory responses in AES cortex [somatosensory evoked responses ∼15 ms later than auditory (Wallace et al., 199 ...
Glia-Derived D-Serine Controls NMDA Receptor Activity and
... acid D-serine (Mothet et al., 2000), which serves as a ligand at the strychnine-insensitive glycine site of NMDA receptors (NMDARs; Johnson and Ascher, 1987). D-serine is synthesized in astrocytes (Stevens et al., 2003; Wolosker et al., 1999) and is released by glutamate receptor stimulation through ...
... acid D-serine (Mothet et al., 2000), which serves as a ligand at the strychnine-insensitive glycine site of NMDA receptors (NMDARs; Johnson and Ascher, 1987). D-serine is synthesized in astrocytes (Stevens et al., 2003; Wolosker et al., 1999) and is released by glutamate receptor stimulation through ...
Document
... If this is true, then one possible means to achieve at least some Cognitive Bias Mitigation is to mimic, as much as possible, Paleolithic/Holocene social, political and economic scenarios when one is performing a reasoning task that could attract negative cognitive bias effects. https://store.theart ...
... If this is true, then one possible means to achieve at least some Cognitive Bias Mitigation is to mimic, as much as possible, Paleolithic/Holocene social, political and economic scenarios when one is performing a reasoning task that could attract negative cognitive bias effects. https://store.theart ...
View PDF - MRC Brain Network Dynamics Unit
... Activity was recorded, first, during slow-wave activity (SWA), which accompanies deep anesthesia and is similar to activity observed during natural sleep, and second, during episodes of sensory-evoked “global activation,” which contain patterns of activity that are more analogous to those observed d ...
... Activity was recorded, first, during slow-wave activity (SWA), which accompanies deep anesthesia and is similar to activity observed during natural sleep, and second, during episodes of sensory-evoked “global activation,” which contain patterns of activity that are more analogous to those observed d ...
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... the subjects are actively attending a visual task (Watanabe et al., 2001; Seitz and Watanabe, 2003). These results suggest that the directed attention facilitates the learning of associated sensory features. ...
... the subjects are actively attending a visual task (Watanabe et al., 2001; Seitz and Watanabe, 2003). These results suggest that the directed attention facilitates the learning of associated sensory features. ...
Research in Mammalian Mastication1
... Carl Gans. As Dr. Gans points out, a major difficulty in attempting any comparison is how one separates and then measures masticatory structure, function, and their development (ontogeny). The problem is made more difficult due to the mosaic nature of biologic systems: Different systems within an or ...
... Carl Gans. As Dr. Gans points out, a major difficulty in attempting any comparison is how one separates and then measures masticatory structure, function, and their development (ontogeny). The problem is made more difficult due to the mosaic nature of biologic systems: Different systems within an or ...
PDF version - Richard Andersen
... from 50 to 270 ms, with median 110 ms. In area 7a, although the and S. These basic phases are common to neurons of both areas range was similar to that of LIP, typically the LS latencies were LIP and 7a. In each phase (LS, M, and S), individual neurons may or may not be active. Most LIP neurons, how ...
... from 50 to 270 ms, with median 110 ms. In area 7a, although the and S. These basic phases are common to neurons of both areas range was similar to that of LIP, typically the LS latencies were LIP and 7a. In each phase (LS, M, and S), individual neurons may or may not be active. Most LIP neurons, how ...
Scrapie in the central nervous system
... 10 y4 units at 98 days p.i., then increased gradually by about 10-fold between 119 and 224 days p.i. Infectivityin optic nerves also increased rapidly between 98 and 140 days p.i., although there was evidence of a low level of infectivity in optic nerve from 21 days p.i. Between one and five of the ...
... 10 y4 units at 98 days p.i., then increased gradually by about 10-fold between 119 and 224 days p.i. Infectivityin optic nerves also increased rapidly between 98 and 140 days p.i., although there was evidence of a low level of infectivity in optic nerve from 21 days p.i. Between one and five of the ...
Selectivity for the Shape, Size, and Orientation of Objects for
... by subtracting the discharge rate during the “reference” period from that during the task period to examine if there were any differences in the mean net activity between the different task conditions (Mann-Whitney U ...
... by subtracting the discharge rate during the “reference” period from that during the task period to examine if there were any differences in the mean net activity between the different task conditions (Mann-Whitney U ...
Hemispheric asymmetries of cortical volume in the human brain
... functional differences between the hemispheres often triggers interest in their morphological differences and vice versa. Indeed, gross morphological differences between the hemispheres are particularly interesting if they can be related to functional differences. The degree to which such relationsh ...
... functional differences between the hemispheres often triggers interest in their morphological differences and vice versa. Indeed, gross morphological differences between the hemispheres are particularly interesting if they can be related to functional differences. The degree to which such relationsh ...
Selectivity for the Shape, Size, and Orientation of Objects for
... orientation of objects for grasping in neurons of monkey parietal area AIP. J. Neurophysiol. 83: 2580 –2601, 2000. In this study, we mainly investigated the visual selectivity of hand-manipulation-related neurons in the anterior intraparietal area (area AIP) while the animal was grasping or fixating ...
... orientation of objects for grasping in neurons of monkey parietal area AIP. J. Neurophysiol. 83: 2580 –2601, 2000. In this study, we mainly investigated the visual selectivity of hand-manipulation-related neurons in the anterior intraparietal area (area AIP) while the animal was grasping or fixating ...
Wild type human TDP-43 potentiates ALS-linked mutant TDP
... while post-natal knockout results in metabolic defects, leading to rapid death [29]. In contrast, heterozygous knockdown results only in a mild impairment in grip strength, with no overt evidence of neurodegeneration [27], while motor neuron specific knockdown results in age dependent progressive mo ...
... while post-natal knockout results in metabolic defects, leading to rapid death [29]. In contrast, heterozygous knockdown results only in a mild impairment in grip strength, with no overt evidence of neurodegeneration [27], while motor neuron specific knockdown results in age dependent progressive mo ...
Please Highlight this Area and Add your Main Title
... The Wistar-Kyoto (WKY) rat is an animal model of clinical depression. Previous research in the laboratory suggests that WKY rats are less responsive to the rewarding and locomotor effects of nicotine compared to Wistar rats. Such strain differences may be due to general, non-specific strain differen ...
... The Wistar-Kyoto (WKY) rat is an animal model of clinical depression. Previous research in the laboratory suggests that WKY rats are less responsive to the rewarding and locomotor effects of nicotine compared to Wistar rats. Such strain differences may be due to general, non-specific strain differen ...
Supplementary Motor Area and Presupplementary Motor Area
... cerebellar projections to two cortical areas on the medial wall of the hemisphere, the supplementary motor area (SMA) and the pre-SMA. We found that both of these cortical areas are the targets of disynaptic projections from the dentate nucleus of the cerebellum and from the internal segment of the ...
... cerebellar projections to two cortical areas on the medial wall of the hemisphere, the supplementary motor area (SMA) and the pre-SMA. We found that both of these cortical areas are the targets of disynaptic projections from the dentate nucleus of the cerebellum and from the internal segment of the ...
Impact of prefrontal cortex in nicotine
... Mansvelder and McGehee, 2000; Mansvelder et al., 2002). Because the interaction between the VTA and other brain regions is interrupted in brain slices, studies in a more intact in vivo system are needed. Emerging evidence demonstrates that the mPFC plays an important role in controlling VTA DA neuro ...
... Mansvelder and McGehee, 2000; Mansvelder et al., 2002). Because the interaction between the VTA and other brain regions is interrupted in brain slices, studies in a more intact in vivo system are needed. Emerging evidence demonstrates that the mPFC plays an important role in controlling VTA DA neuro ...