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Name: __________________________ Lesson 3 & 4 Genetics Lesson 3: How dochildren get traits that their parents do not have? And how do traits skip a generation? 1. Do you know children who have traits that their biological parents do not have? Have you ever heard of a trait that “skips a generation”? In this lesson, we will explore these questions and find a model that can explain how this happens. 2. Your teacher will show you a powerpoint to help you. 3. In the last lesson, you decided that the best model was the strong gene model. In this lesson, your teacher will introduce you to two different “strong allele” models, and you will try out the two models and see how they work. One Allele Model – Each parent contributes one allele, and the “strongest” allele is the one that determines what trait the children have. Two Allele Model – Each parent has two alleles of their own, and each gives one to the child. The strongest allele in the pair determines what trait the child will have. 4. Your teacher will walk you through a simulation using genetic boxes to help explain the two models. 6. Below are four pieces of evidence. In pairs, read each piece of evidence. 7. Individually, complete the arrows diagram for Evidence 1 through 4. Discuss your arrows with your partner. Give clear reasons to each other for your ideas, and discuss carefully any arrows you disagree about. Evidence Evidence 1: Cats Evidence 2: Skip a generation Evidence 3: Shondra, Dan and Derrick Evidence 4: Kumar Family One Allele Model Two Allele Model 8. Individually, answer this question: How is Evidence #2 related to the Two Allele Model (supports, contradicts, etc.). Give reasons for your answer using details from the evidence. ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ 9. Individually, answer this question: How is Evidence #2 related to the One Allele Model (supports, contradicts, etc.)? Give reasons for your answer using details from the evidence. ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ 10A. Discuss in your groups: Which model is better, based on the evidence so far. Give detailed reasons for your ideas during your discussion (use model evaluation stems). 10B. Then answer the following questions. Which evidence is the best evidence? Which evidence supports or contradicts both models MOST STRONGLY? Which evidence helps you the most to decide which model is better? What is the best argument for the Two Gene Model? What is the best argument for the One Gene Model? 11. Individually, answer this question. Which is the best “strong” allele model? Give 2 reasons with detailed explanations using the evidence provided. ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ ______________________________________________________________________________ LESSON 4 - DNA YARN ACTIVITY Next we will use a physical model made of yarn on a popsicle stick to show how the two-gene model works. You will also learn these important terms in genetics: DNA, gene, allele, and chromosome. Our goal is to learn how to use these terms when talking about adults and their children. Step 1: Tie together the different length pieces of the colored yarn. The strings will be different lengths, this is o.k. Tie them together in this order: Brown – Purple – Green – Yellow – Red – Blue Step 2: After you have tied the pieces of yarn together, tape one end of the piece of yarn to one end of the Popsicle stick. Step 3: Wrap the yarn around the Popsicle stick. Step 4: Tape the other end of yarn to the popsicle stick. Step 5: Repeat steps 1 – 4 for the other popsicle stick. Below is the table of traits showing the color of the wool and whether it is dominant or recessive. Wool Color Trait Dominant Dark brown Dimples Light brown No Dimples Dark purple Unattached Earlobes Light purple Attached Earlobes Dark green Widow's Peak Light green Straight Hairline Dark yellow Straight Thumb Light yellow Curved Thumb Dark red Can Roll Tongue Light red Can't Roll Tongue Dark blue Can Taste PTC Light blue Can't Taste PTC Recessive X X X X X X X X X X X X 1. Humans have 46 chromosomes. These come in pairs of 2, so there are 23 pairs of chromosomes. The information for each trait can be found on a pair of chromosomes. Now that we have 2 chromosomes with multiple alleles (different shades of yarn) we can figure out the traits for this adult. Fill in the table below for your traits. Your teacher will put an example on the board to help you fill in the table. Wool Color on Chromosomes - write whether it is light or dark Individuals Genotype write whether it is dominant or recessive Brown / / Purple / / Green / / Yellow / / Red / / Blue / / Individuals Phenotype - write in their trait 2. With your partner, each person should randomly pick one chromosome from the pair that they made. Set the other chromosome off to the side, it will not be used. Now pair your remaining chromosome with your partner. Make sure it is not the one you set off to the side. This new pair of chromosomes is one possible child who gets half their DNA from one parent and half their DNA from the other parent. 3. For this new individual fill in the table below for your traits. Wool Color on Chromosomes - write whether it is light or dark Individuals Genotype write whether it is dominant or recessive Brown / / Purple / / Green / / Yellow / / Red / / Blue / / Individuals Phenotype - write in their trait Just in case you need it we have included the trait below to help you out. Wool Color Trait Dark brown Dimples Light brown No Dimples Dark purple Unattached Earlobes Light purple Attached Earlobes Dark green Widow's Peak Light green Straight Hairline Dark yellow Straight Thumb Light yellow Curved Thumb Dark red Can Roll Tongue Light red Can't Roll Tongue Dark blue Can Taste PTC Light blue Can't Taste PTC Dominant Recessive X X X X X X X X X X X X