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Answer Key for Module # 7 Care of the Individual with Diabetes Match these terms with the appropriate description. 1. h 2. g 3. j 4. c 5. d 6. a 7. e 8. b 9. f 10. k 11. i 12. l Fill in the blanks using the terms provided. 1. Somogyi Phenomena 2. Diabetic Ketoacidosis 3. Diabetes Mellitus 4. Hyperosmolar Hyperglycemic State 5. Macroangiopathy 6. Microangiopathy 7. Diabetic Retinopathy 8. Diabetic Nephropathy 9. Diabetic Neuropathy 10. Infection 11. Peripheral Vascular Disease 12. Lipodystrophy Complete the following comparing Type 1 and Type 2 Diabetes. FACTOR Etiology Risk Factors TYPE 1 Absolute insulin deficiency with glucagon excess causing hyperglycemia Idiopathic in some cases Destruction of beta cells by islet cell and insulin autoantibodies Surgical removal of the pancreas due to trauma, cancer, etc Destruction of the beta cells as in chronic pancreatitis Genetic predisposition TYPE 2 Impaired insulin production (Pooped Pancreas) and (Leaky Liver) from increased glucose production from action of glucagon in the liver. Severe peripheral resistance to available insulin Obesity in abdomen esp. upper Viral illness as mumps, rubella, or coxsackievirus B4 Exposure to chemical toxins Often occurs in childhood or adolescence but can occur at any age Exposure to steroids as at onset of puberty, pregnancy, or in extreme stress situations Common in pts. of African or Asian descent Symptoms at onset Sudden onset of symptoms Polyuria & glucosuria Osmotic diuresis Bed wetting in children or the elderly Polydipsia Polyphagia Marked weight loss Weakness and fatigue Irritability Treatment Require insulin Meal planning to meet caloric demand and offset calories needed for activities Exercise Blood glucose monitoring Education Ketoacidosis Characteristic Danger by Type of Diabetes body & at least 20% over desired wt. Sedentary lifestyle Family history of Type 2 diabetes Often occurs at middle-age or older but can occur at any age. Common in pts. of African, Hispanic/Latin American, & Native American descent Women with gestational diabetes, Delivery of a baby weighing > 9 lb., polycystic ovary syndrome. Hypertension = or > 130/85 HDL = or > 35 Triglyceride level = or > 250 mg/dl Gradual onset of symptoms Polyurea Polydipsia Fatigue Blurred vision Slow wound healing Numbness, tingling in hands & feet Dry itchy skin Frequent infections as of skin Diagnosed when treated for complications Usually enough insulin to prevent ketone formation Meal Planning & Exercise Oral mediations Insulin in times of stress & if not responsive to oral meds Blood glucose monitoring Education Hyperosmolar Hyperglycemic State Complete this table comparing key facts related to common types of insulin. Type of Insulin Key Information Onset of Action Peak of Action Duration of Action Aspart Novolog Lispro Humalog Rapid Acting (Shoot & Eat) Rapid acting (Shoot & Eat.) Can take 15 min. before eating or after eating. Is good for people with an unpredictable eating schedule. Short acting. Give 20 to 30 minutes ac. Only insulin that is given IV or IM in emergencies. Intermediate Acting. Given alone or mixed with shorter acting insulin such as Regular or Lispro/Humalog. Long acting. Rarely used. Cannot be mixed with any other type of insulin. Commonly used. Give 30 minutes before breakfast & supper if using Humulin or Novolin 15 minutes 1 to 3 hours 3 to 5 hours 15 minutes 1 to 1.5 hours 3 to 4 hours 30 min. to 1 hour 2 to 3 hours 4 to 6 hours 2 hours 6 to 8 hours 12 to 16 hours 2 hours 16 to 20 hours 24 + hours 1 to 2 hours No peak 24 + hours 30 minutes 4 to 8 hours 24 hours Regular NPH and Lente Ultralente Glargine Lantus 70/30 Each ml. contains 70 units of NPH & 30 units of Regular insulin. (Commonly used type is Humulin.) Caution: 70/30 is also made with Novolin insulin or Novolog insulin. Any Novolog product is shoot and eat! Read the label carefully. 50/50 each ml. contains 50 units of NPH & 50 units of Regular insulin 75/25 each ml. contains 75 units of Lispro protamine & 25 units of Lispro. types. Give just before or just after eating if using the Novolog type. Commonly used due to ease in preparation if the proportions are appropriate for the patient. If using Humulin 70/30 with an additional Humalog sliding scale, give Humalog in a separate syringe immediately before the meal. Used less often than 70/30 insulin. 30 minutes Give just before 15 minutes breakfast & just before supper. (Contains shoot & eat insulin.) Use is increasing in popularity. 3 hours 22 to 24 hours About 4 to 8 About 24 hours hours * Some sources state that peaking begins at about 2 hrs. Review key concepts about oral agents by filling in the blanks using information provided in the preceding chart. 1. Prandin & Starlix 2. Amaryl, DiaBeta, & Glucotrol – stimulation of Beta cells to release insulin 3. slowing the breakdown of carbohydrates and decreasing absorption of glucose in the small intestine 4. milk 5. Glucophage or metformin 6. Avandia and Actos 7. Precose and Glyset 8. Glucophage or metformin 9. Actos & Avandia 10. Amaryl, DiaBeta, Glucotrol, Prandin, & Starlix 11. Prandin & Starlix which provide insulin and Precose & Glyset which block breakdown & absorption of carbohydrates 12. Amaryl, DiaBeta, & Glucotrol 13. decreasing release of glucose from the liver Mark the item(s) that correctly address the statements provided. 1. a. destruction of Beta cells not alpha cells b&c d. Beta cells are the ones attacked by the autoimmune response 2. a, c, & d b. breast milk is considered a deterrent to stimulation of the autoimmune response that attacks the beta cells and Diabetic mothers have no known bad impact on this protective process. 3. c, d, & f a. most Type 1 diabetics are children or adolescents at the time of diagnosis b. most have rapid weight loss e. dehydration occurs rather than fluid retention 4. a, b, d, & e c. sedentary and/or high stress lifestyles are common and contribute to Type 2 diabetes 5. b, c, f, & g a. ketones are rarely produced in Type 2 diabetics because they produce enough insulin to prevent the breakdown of fats d. numbness & tingling are present in the extremities and there is general dryness of the skin 6. b, c, & d a. complex carbohydrates are an acceptable part of a diabetic’s diet and a small amount of sugar is permitted within the diet plan. e. high fiber foods are encouraged and appropriate quantities of carbohydrates are part of the diet 7. b & c a. Random Plasma Glucose equal or greater than 200 mg/dl d. Hemoglobin A1c is not usually used to diagnose diabetes 8. a & b c. 100 to 140 mg/dl at bedtime d. There is no average blood sugar value used as a goal and 250 is a high reading. Instead, a Hemoglobin A1c of 6.5% is an indicator of blood sugar control over the preceding 2 to 3 month period. Returning to ones diet and taking ones medications just before Hemoglobin A1c testing will not improve the findings. 9. b, c, d, & e a. too little food and too much insulin contribute to hypoglycemia 10. a, c, e, & g b. give 15 grams of simple sugar not protein every 15 minutes if blood sugar finding reveals the need for it. d. use 1 cup skim or low fat milk and avoid chocolate because high fat content in foods will delay absorption and may result in additional temporary even dangerous drop in the person’s blood sugar level. f. avoid adding sugar to the 4 oz. of juice or regular soda to avoid swinging the patient into a hyperglycemic state. 11. a, b, c, d, & e f. the patient with normal kidney function would usually have an increased urine output. 12. a, b, d, & e c. Type 1 diabetics should NOT exercise if blood sugar is > 250 mg/dl and ketones are present in the urine. 13. b & d a. avoid washing in hot water to prevent burns. Test water with a sensitive body part or a bath thermometer. c. apply lotion or creams to all parts of the feet except between the toes if skin is dry to help avoid fungal infections. e. avoid application of strong chemicals to the feet because they are likely to delay healing and may cause additional damage to the skin. Assess all extremity lesions carefully at least once a day and see the physician for wounds that do not heal within a few days or if they worsen. 14. b, d, f, g, & h a. buy shoes in the afternoon when feet are a little swollen to avoid getting shoes that are too tight. c. buy shoes that are a good fit and do not need to be “broken in.” e. avoid wearing sandals and open backed shoes as well as high heeled shoes because of the increased danger of injury. 15. a, d, & e b. use socks for increased warmth for cold feet and avoid heating pads which may cause burns because of loss of sensation. c. ice may cause tissue damage because of loss of sensation and may further compromise already bad circulation to the foot. Indicate whether the following items are true or false. 1. 2. 3. 4. 5. 6. T T False, Type 1 Diabetics should test their blood sugar 4 times a day. T T False Wash hands in warm water and milk the finger prior to sticking it to avoid diluting the sample with serous fluid also remember to let alcohol dry prior to sticking the finger for the same reason. 7. T 8. False Glucose meters should be checked frequently because the insulin or oral medication dose depends on accurate measurement. Wrong data could result in hyperglycemia or hypoglycemia. 9. T 10. False Lantus (Glargine) insulin has no identified peak and is known for its constant effect. 11. T 12. T 13. T 14. T 15. False Prior to surgery, the oral medications are usually held but the nurse should discuss with and obtain an order from the surgeon addressing administration of insulin. Often the patient’s sugar is tested during surgery and treated appropriately in combination with the IV fluids being administered. 16. False Type 2 diabetics often require subcutaneous insulin during stressful illnesses or surgery. Most of the time they are able to return to their usual manner of treatment once their condition improves. 17. False Cloudy insulins such as NPH or Lente should NOT contain floating particles or deposits that will not disperse with gentle rolling. If this occurs the vial should be discarded and a new one opened. 18. T 19. T 20. Diabetics with signs and symptoms of a systemic allergic reaction should seek immediate medical attention as per EMS rather than delaying to discus this with their physician.