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BHARATESH HOMOEOPATHIC MEDICAL COLLEGE & HOSPITAL, POST GRADUATE RESEARCH CENTRE BELGAUM-590016, KARNATAKA Recognised by CENTRAL COUNCIL OF HOMOEOPATHY, NEW DELHI Affiliated to RAJIV GANDHI UNIVERSITY OF HEAITH SCIENCES, BANGALORE SYNOPSIS M.D. (HOMOEOPATHY) “A STUDY OF TINEA CORPORIS &ITS CONSTITUTIONAL APPROACH” By DR.TAIMIMKOUSAR.M.KHADAKWALE Under the Guidance of DR.M.N.SHAIKH MD (HOM) Professor, HOD & P. G. Guide, DEPARTMENT OF HOMOEOPATHIC MATERIA MEDICA BHARATESH HOMOEOPATHIC MADICAL COLLEGE & HOSPITAL From, Dr. TAIMIMKOUSAR To, DR. M.N.SHAIKH M.D (HOM) Professor, H.O.D & P.G. Guide, Department of Organon Of Medicine & Homeopathic Philosophy Bharatesh Homoeopathic Medical College & Hospital, Belgaum. Sub: Application to my synopsis for the dissertation Respected Sir, I Dr. TAIMIMKOUSAR, would like to forward my application for the approval of my synopsis under your Guidance for the following topics, “A STUDY OF TINEA CORPORIS & ITS CONSTITUTIONAL APPROACH ” Hope you will approve the same Thanking you. Date: Place: Belgaum. Yours Sincerely Dr.TAIMIM KOUSAR Department of Organon of Medicine &Homoeopathic Philosophy Bharatesh Homoeopathic medical College and hospital From, DR. M.N.SHAIKH M.D (HOM) Professor, H.O.D & P.G. Guide, Department of Organon Of Medicine & Homeopathic Philosophy Bharatesh Homoeopathic Medical College & Hospital, Belgaum. To, Dr. TAIMIM KOUSAR Sub: Acceptance of synopsis for the dissertation Dear Doctor, I have accepted your topic, “A STUDY OF TINEA CORPORIS & ITS CONSTITUTIONAL APPROACH ”For the dissertation. Your synopsis will forward to RGUHS. Date: Place: Belgaum DR. M.N.SHAIKH M.D (HOM) Professor, H.O.D & P.G. Guide, Department of Organon Of Medicine & Homeopathic Philosophy Bharatesh Homoeopathic Medical College & Hospital, Belgaum. RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES, KARNATAKA, BANGALORE ANNEXURE II APPLICATION FOR THE REGISTRATION OF SUBJECT FOR DISSERTATION 1. NAME OF THE CANDIDATE & ADDRESS DR.TAIMIMKOUSAR.M.KHADAKWALE POST GRADUATE STUDENT , BHARATESH HOMOEOPATHIC MEDICAL COLLEGE AND HOSPITAL, BELGUAM PERMANENT ADDRESS DR.TAIMIMKOUSAR.M.KHADAKWALE c/o AFZAL HUSSAINS.A.SHAIKH. PLOT NO:53 SECTOR NO:2 SHIVABASAVANAGAR BELGAUM-590016 2. NAME OF INSTITUTION BHARATESH HOMOEOPATHIC MEDICAL COLLEGE AND HOSPITAL, DHARWAD ROAD BELGUAM (KARNATAKA). 3. COURSE OF STUDY AND SUBJECT DOCTOR OF MEDICINE (HOMOEOPATHY) ORGANON OF MEDICINE &HOMEOPATHYIC PHILOSOPHY 4. DATE OF ADMISSION 31-10-2011 TO COURSE 5. TITLE OF THE TOPIC “A STUDY OF TINEA CORPORIS & ITS CONSTITUTIONAL APPROACH ” 6. BRIEF RESUME OF THE INTENDED WORK 6.1 NEED FOR THE STUDY Tinea Corporis is seen world wide is the most common in the tropical region, any dermatophyte can potentially cause tinea corporis but T Rabrum is the most common pathogen world wide follow by T Mentagrophyte. Sites of predilection are the neck upper and lower extremities and trunk it can be caused by any dermatophytes. This form of ringworm is characterized by one or more circular, sharply circum scribed slightly erythematous, dry scaly usually hypopigmented Patches. The modern system of medicines makes the usage of external application like ointments, fungicides etc, which leads to suppression or palliation. So the disease tends to recur often and becomes a chronic disease. The disease is usually chronic and the course extends over months to years eczematisation and lichenification may become the complicating features of chronic cases half hearted treatment is demoralizing and results in chronicity. As Homeopathy is a system of medicine which work on inspiration the humoral or the immune mechanism of the body from its latent or overt reaction ,it is there by the best form of medicine to treat skin diseases here the cure is obtained by constitutional treatment . The sum total of the individual characteristics in the three planes –emotional, intellectual & physical-depicts the constitution. This some total is the resultant of the environmental factor, right from the time of conception, acting on the hereditary plan of organization as determined genes. Therefore individual illness cured if only we can clearly understand the constitution. A systemic study on scientific line is needed to conclude on the effect of homoeopathy medicine in the treatment of tinea corporis hence study is under taken. Hypothesis: Constitutional approach to Tinea Corporis may be effective. 6.2 REVIEW OF LITERATURE Tinea corporis is the commonest clinical variety of dermatophyte infection in India. It is distributed world wide.(1) It is most common in tropical regions. Tinea corporis manifests itself as Marked itching, vesicles pustules or scaling; these vary from case to case depending upon the virulence of the fungus and sensitivity of the individual.(2) The disease is usually chronic and the extent over month to year eczematisation and linchenification may become complication features of chronic cases.(3) Hugein his manual of Therapeutic say that Herpss circinnatus (ring worm of the surface) is usually treated and with fair success by sepia, but that when the proving of Tellurium produced so similar an eruption, he (Dr. Hunges) followed Dr.Metcalf in prescribing it instead of sepia for this disorder and has never failed to cure in speedily there by. Hence, it appear that there is a wide scope for proper management and treatment of tinea corporis in homoeopathy. The modern system of medicine adopts the usage of antifungal or fungicides, externally or internally. But the side effects of this treatment out weight benefits and is only a palliation.(6) PREDISPOSING FACTOR 1. Tinea corposis may be transmitted by direct contact with other infected individuals or by infected animals1. Transmission of infection by clothing furniture or any other sites in the same patients.(2) 2. Risk factors for infection include exposure to infected animals persons soil, athlete, veterinarians, animal handlers .(3) 3. In addition certain systemic disease may predispose to infection including cashing’s syndrome, D.M.atropy and most immuno deficiency syndromes .(4) PATHOGENESIS : Dermatophytes grow only on the keratinised layers of the skin and its appendages and do not ordinarily penetrate the living tissues. Fungal products may be responsible for inciting local inflammation. Hypersensitivity to fungus antigens may play a role in pathogenesis and is probably responsible for the sterile vesicular lesions some times seen in distant from the ring worm.(2) The organism responsible for tinea corporis invades the stratum corneum, possible aided by warm moist occlusive conditions and resides in it. After about 1-3 weeks of incubation it starts spreading centrifugally.(4) Serum inhibitory factor may be responsible for limiting this infection. Chronicity and further spread of infection. Dermatophytes unlike most other fungi produce keratinases (Enzymes that break down Keratin) which allow for invasion of the fungi into kerotinized tissue. Mannans in the cell walls of dermatophytes have immuno inhibitory effects. The severity of clinical disease is affected by several host factors, sebum has an inhibitory effect on dermatophytes, and the level of disease activity may be related to the number and activity of sebaceous glands, and increased susceptibility may be inherited or related to the competency of the immune system.(3) COMPLICATION: Half hearted treatment is demoralizing and results in chronicity: (3,4) 1) eczematisation 2) lichenification. DIAGNOSIS: Laboratory findings for the correct diagnosis tinea corporis the spreading ringworm with active erythumotous border-specimens for KOH examination should be obtained from the actively spreading border of the lesion.(1) Microscopic examination of skin scrapings for fungi is essential in dermatologic. Fungal eruptions may closely resemble dermatitis. Microscopy of potassium hydroxide-cleared skin scrapings called a KOh exam takes only a few minutes and is simple principle doing it.(3,4) Thus in homeopathy, constitutional is defined as physical and mental makeup of individual. Constitution is a phenomenon i.e. I has antecedents; it evolves over period of times and unfold in itself by constant interaction with the environment. Constitutional presiding is a holistic approach of homoeopathic treatment where prescription is not based on isolated systems, but on the characteristics , unearthed by proper, in depth case taking ;this information is then matched to a single remedy.(5) J.Compton Burnett Quotes: I seek to show that the so called diseases of the skin are for the most part diseases of the constitutions of the persons, and not diseases of theirs. Many cutaneous manifestations be taken in a certain sense, constitutional power organism has the power to determine its diseases to the periphery to its outside. It is a smaller evil to have it outside on the skin than to have it inside in a given organ. The trichophyton is not the disease itself but its organic scavenger cure the internal disease, and this scavenger dies.(6) Chatterji.TP: Defines constitution as “It is the inherited qualities cum environment, having genetic background.(7) Constitutions types according to Dr. Hahnemann : After years of patient observation Hahnemann saw that a superficial symptom resemblance between drugsymptoms and disease-symptoms was sometimes insufficient to show the true specific correspondence eventually he tracked down the underlying constitutional dyscrasiae to the 3 miasms” and he named them, syphilis, sycosis and psora.(8) Thomas. P. Paschero, tells us: “Homoeopathy views the constitution as a pathogenic dynamism which the individual inherits and modifies during his life, in three distinct directions. Inflammation, destruction of tissue, or its proliferation. These dynamic morbid tendencies were called by Hahnemann ‘miasms’ a term comparable to ‘diathesis’ dyscrasia terrain; or constitution and he gave them the names, psora, syphilis, and sycosis.(9) J.H. Allen say: Sycosis as well as pseudo psora we see them in the vegetable parasitical pest as seen in tinea. We see the animal parasite in the psoric and pseudopsoric; probably no skin disease show such a special form of sycotic expression as we find in Tinea barbae, Tinea tonsuraus, Tinea vesicular and similar diseases of the face, scalp and other part of the body, when they are suppressed, they develop for their sycotic difficulties of a sycotic nature.(10) Some of the constitutional remedies used for Tinea Corporalis are:(11) SULPHUR: skin dry scaly unhealthy; every little injury suppurate, Itching ,burning ; worse scratching and washing .pimple eruption ;worse scratching and watching pimple eruption pustules. rhagades, hang nail, excoriation especially in folds .feeling of bands around bone skin affection after local medication pruritus especially from warmth in evening often recur in spring time in dame weather. SEPIA : Ringworm like eruption every spring. Urticaria on going in open air; better in warm room hyperidrosis and bromidrosis. sweat on feet ,worse on toes ; intolerable odor lentigo in young women. ichthyosis with offensive odor of skin. itching is not relive by scratching worse in bends of elbow and knee. TELLURIUM : Itching of hands and feet herpetic spots ring shape lesion of offensive odour from affected part barber itch stinging in skin fetid exhalation offensive foot sweat eczema back of ear and occiput, circular patch of eczema worse at night ,cold whether, from friction. 6.3 AIMS AND OBJECTIVE OF THE STUDY : To study the clinical presentation of tinea corporis. To study the efficacy of Homoeopathic medicines in treatment of tinea corporis. To study the miasmatic interpretation of tinea corporis to assess the predominant miasm. 7. MATERIAL & METHODS : 7.1 SOURCES OF DATA : The cases of the study will be collected from OPD. Rural and Regular camp visits of Bharatesh Homoeopathic Medical College & Hospital Road, Belgaum. 7.2 METHODS OF COLLECTION OG DATA (INCLUDING SAMPLE PROCEDURE, IF ANY) Patients will be considered on including and exclusion criteria. Patients are considered on the basis of clinical presentations. Minimum sample size will be 30. Sample random sampling will be adopted. All cases will be taken as per the Performa for the study. > All patients registered between periods of November 2011 to July 2013 will be selected. No new cases will be taken for study after July 2013. All cases shall be followed up for period of 2-6 months. Follow up will be seen weekly or fortnightly as per requirement. Physical, radiological & laboratory examinations done periodically whenever needed. Prognosis: Assessment will be based on the general and local improvement of the Patients. Recovered. Improved. Not improved. Inclusion criteria: Patient suffering from TINEA CORPORALIS on the basis of clinical history and finding. Patients of all age groups and both the sexes will be considered. Exclusion criteria: Cases with complication of TINEA CORPOLIS. Complication-LICEANIFICATION &ECZEMITIZATION. Patient secondary should be excluded. to DM; HTN; complication of DM (Gangrene) 7.3 DOES THE STUDY REQUIRE ANY INVESTIGATION OR INTERVENTION TO BE CONDUCTED ON THE PATIENTS OR OTHER HUMAN OR ANIMALS? IF SO DESCRIEB BRIEFLY. The diagnosis of the cases will be done on eliciting cases history and clinical findings, other required investigation is, 1) Microscopic- fungus under the microscopic in skin scraping. 2) Culture- skin scarping can be cultured on a suitable medium. 7.4 ETHICAL CLEARANCE BEEN OBTAINED FROM YOUR INSTITUTION IN CASE OF 7.3? Yes, Ethical clearance has been obtained from the institution. 8. LIST OF REFERENCES: 1. Ananth Narayan R. Jayaram Paniker C.K., Textbook of Microbiology. 7th Edition. Chennai: orient Longman Pvt Ltd; 2005. Pg no 606. 2. Jean Bolognia, Joseph L. Jari 220, Ronald. P. Roipini. Dermatology volume 1, 1st ed. London: Mos by ; 2003.pg no 1174-1185. 3. Thomas .B. Fitzpatrick, Arthur z. Eisen, Irwin M. Freed burg, F. Frank austen Dermatology in General 2nd. Vol, 4th ed. New York : Mc Graw Hill ; 1993.pg no 2212-2217. 4. Aggarwal BN. Govind Srivastava. Practice of Dermatology 10th ed. New Delhi: Satish Kumar Jain For C.B.S;2005 pg no 167. 5. Kent JT. Lectures on Homoeopathy philosophy.NewDelhi-1005. B.Jain publisher(p)Ltd;1999. Pg no 120 6. Burnett JC. Ringworm. New Delhi : Indian Books and periodicals ; .pg no 129. 7. Chatterji TP. Fundamentals of Homoeopathy and valuable Hints for practice. 4th ed. New Delhi : New Delhi : B.Jain publishers (P) Ltd ; 1993.pg no 77-79. 8. Hahnemann S. Organon of Medicine. Reprinted : New Delhi : B.Jain publishers (P) Ltd ; 1997.pg no35. 9. Ortega PS. Notes on the miasms. Ist English ed. New Delhi National Homoeopathic pharmacy ; 1980.pg no 44. 10. Allen JH. The chronic miasms psora pseudo psora and sycosis Reprinted ed. New Delhi : Mayur Jain Indian Book and periodicals ; 2004. Pg no 267. 11. Boericke W. Pocket book manual of homoeopathic materia medica and repertory. Reprinted New Delhi: B.Jain Publisher(p)Ltd;1980.pg no520,580,635. 12. http//WWW.aocd.org/skin/dermatological disease/dermatitis. 9 SIGNATURE OF THE CANDIDATE 10 REMARKS OF THE GUIDE 11 NAME OF THE DESIGNATION OF (IN BLOCK LETTERS) 11.1 GUIDE DR. M.N.SHAIKH.M.D.(HOM) PROFESSOR, H.O.D & P.G.GUIDE DEPARTMENT OF ORGANON OF MEDICINE AND HOMOEOPTHY PHILOSOPHY, BHARATESH HOMOEOPATHIC MEDICAL COLLEGE, BELGAUM- 16 11.2 SIGNATURE 11.3 CO-GUIDE (IF ANY) 11.4 SIGNATURE 11.5 HEAD OF THE DEPARTMENT 12. SIGNATURE 12.1 REMARKS OF THE CHAIRMAN AND PRINCIPAL 12.2 SIGNATURE DR. M.N.SHAIKH. M.D.(HOM) PROFESSOR, H.O.D, GUIDE DEPARTMENT OF ORGANON OF MEDICINE AND HOMOEOPTHY PHILOSOPHY, BHARATESH HOMOEOPATHIC MEDICAL COLLEGE, BELGAUM- 16