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Standard 14 : Organization and Development of Living Organisms This document was generated on CPALMS - www.cpalms.org A. Cells have characteristic structures and functions that make them distinctive. B. Processes in a cell can be classified broadly as growth, maintenance, reproduction, and homeostasis. C. Life can be organized in a functional and structural hierarchy ranging from cells to the biosphere. D. Most multicellular organisms are composed of organ systems whose structures reflect their particular function. Number: SC.912.L.14 Title: Organization and Development of Living Organisms Type: Standard Subject: Science Grade: 912 Body of Knowledge: Life Science Related Benchmarks Code SC.912.L.14.1: Description Describe the scientific theory of cells (cell theory) and relate the history of its discovery to the process of science. Remarks/Examples: Describe how continuous investigations and/or new scientific information influenced the development of the cell theory. Recognize the contributions of scientists in the development of the cell theory. SC.912.L.14.2: SC.912.L.14.3: Relate structure to function for the components of plant and animal cells. Explain the role of cell membranes as a highly selective barrier (passive and active transport). Compare and contrast the general structures of plant and animal cells. Compare and contrast the general structures of prokaryotic and eukaryotic cells. Remarks/Examples: Annually Assessed on Biology EOC. Also assesses SC.912.L.14.2. SC.912.L.14.4: SC.912.L.14.5: SC.912.L.14.6: SC.912.L.14.7: Compare and contrast structure and function of various types of microscopes. Explain the evidence supporting the scientific theory of the origin of eukaryotic cells (endosymbiosis). Explain the significance of genetic factors, environmental factors, and pathogenic agents to health from the perspectives of both individual and public health. Relate the structure of each of the major plant organs and tissues to physiological processes. Remarks/Examples: Annually Assessed on Biology EOC. SC.912.L.14.8: SC.912.L.14.9: SC.912.L.14.10: SC.912.L.14.11: SC.912.L.14.12: SC.912.L.14.13: SC.912.L.14.14: SC.912.L.14.15: SC.912.L.14.16: SC.912.L.14.17: Explain alternation of generations in plants. Relate the major structure of fungi to their functions. Discuss the relationship between the evolution of land plants and their anatomy. Classify and state the defining characteristics of epithelial tissue, connective tissue, muscle tissue, and nervous tissue. Describe the anatomy and histology of bone tissue. Distinguish between bones of the axial skeleton and the appendicular skeleton. Identify the major bones of the axial and appendicular skeleton. Identify major markings (such as foramina, fossae, tubercles, etc.) on a skeleton. Explain why these markings are important. Describe the anatomy and histology, including ultrastructure, of muscle tissue. List the steps involved in the sliding filament of muscle contraction. SC.912.L.14.18: SC.912.L.14.19: SC.912.L.14.20: SC.912.L.14.21: SC.912.L.14.22: SC.912.L.14.23: SC.912.L.14.24: SC.912.L.14.25: Describe signal transmission across a myoneural junction. Explain the physiology of skeletal muscle. Identify the major muscles of the human on a model or diagram. Remarks/Examples: Refer to MAFS.K12.MP.4: Model with mathematics. Describe the anatomy, histology, and physiology of the central and peripheral nervous systems and name the major divisions of the nervous system. Describe the physiology of nerve conduction, including the generator potential, action potential, and the synapse. Identify the parts of a reflex arc. Identify the general parts of a synapse and describe the physiology of signal transmission across a synapse. Identify the major parts of a cross section through the spinal cord. Identify the major parts of the brain on diagrams or models. Remarks/Examples: SC.912.L.14.26: Annually Assessed on Biology EOC. Florida Standards Connections: MAFS.K12.MP.4: Model with mathematics. SC.912.L.14.27: SC.912.L.14.28: SC.912.L.14.29: SC.912.L.14.30: SC.912.L.14.31: SC.912.L.14.32: SC.912.L.14.33: SC.912.L.14.34: SC.912.L.14.35: SC.912.L.14.36: Identify the functions of the major parts of the brain, including the meninges, medulla, pons, midbrain, hypothalamus, thalamus, cerebellum and cerebrum. Identify the major functions of the spinal cord. Define the terms endocrine and exocrine. Compare endocrine and neural controls of physiology. Describe the physiology of hormones including the different types and the mechanisms of their action. Describe the anatomy and physiology of the endocrine system. Describe the basic anatomy and physiology of the reproductive system. Describe the composition and physiology of blood, including that of the plasma and the formed elements. Describe the steps in hemostasis, including the mechanism of coagulation. Include the basis for blood typing and transfusion reactions. Describe the factors affecting blood flow through the cardiovascular system. SC.912.L.14.37: SC.912.L.14.38: SC.912.L.14.39: SC.912.L.14.40: SC.912.L.14.41: SC.912.L.14.42: SC.912.L.14.43: SC.912.L.14.44: SC.912.L.14.45: SC.912.L.14.46: SC.912.L.14.47: SC.912.L.14.48: SC.912.L.14.49: SC.912.L.14.50: SC.912.L.14.51: SC.912.L.14.52: Explain the components of an electrocardiogram. Describe normal heart sounds and what they mean. Describe hypertension and some of the factors that produce it. Describe the histology of the major arteries and veins of systemic, pulmonary, hepatic portal, and coronary circulation. Describe fetal circulation and changes that occur to the circulatory system at birth. Describe the anatomy and the physiology of the lymph system. Describe the histology of the respiratory system. Describe the physiology of the respiratory system including the mechanisms of ventilation, gas exchange, gas transport and the mechanisms that control the rate of ventilation. Describe the histology of the alimentary canal and its associated accessory organs. Describe the physiology of the digestive system, including mechanical digestion, chemical digestion, absorption and the neural and hormonal mechanisms of control. Describe the physiology of urine formation by the kidney. Describe the anatomy, histology, and physiology of the ureters, the urinary bladder and the urethra. Identify the major functions associated with the sympathetic and parasympathetic nervous systems. Describe the structure of vertebrate sensory organs. Relate structure to function in vertebrate sensory systems. Describe the function of the vertebrate integumentary system. Explain the basic functions of the human immune system, including specific and nonspecific immune response, vaccines, and antibiotics. Remarks/Examples: Annually Assessed on Biology EOC. Also assesses SC.912.L.14.6 HE.912.C.1.7 and HE.912.C.1.5. SC.912.L.14.53: Related Access Points Independent Discuss basic classification and characteristics of plants. Identify bryophytes, pteridophytes, gymnosperms, and angiosperms. Access Point Number SC.912.L.14.In.1: SC.912.L.14.In.2: SC.912.L.14.In.3: SC.912.L.14.In.4: SC.912.L.14.In.5: Access Point Title Identify that all living things are made of cells and cells function in similar ways (cell theory). Identify the major parts of plant and animal cells, including the cell membrane, nucleus, and cytoplasm, and their basic functions. Identify that parts of cells (organelles) can combine to work together. Describe common human health issues. Describe the general processes of food production, support, water transport, and reproduction in the major parts of plants. Supported Access Point Number SC.912.L.14.Su.1: SC.912.L.14.Su.2: SC.912.L.14.Su.3: SC.912.L.14.Su.4: Access Point Title Identify that the cell is the smallest basic unit of life and that all living things are made of cells. Recognize that cells have different parts and each has a function. Recognize common human health issues. Relate parts of plants, such as leaf, stem, root, seed, and flower, to the functions of food production, support, water transport, and reproduction. Participatory Access Point Number SC.912.L.14.Pa.1: SC.912.L.14.Pa.2: SC.912.L.14.Pa.3: SC.912.L.14.Pa.4: Access Point Title Match parts of common living things to their functions. Recognize that small parts of a living thing can work together. Identify ways to prevent infection from bacteria and viruses, such as hand washing and first aid. Recognize major plant parts, such as root, stem, leaf, and flower. Related Resources Text Resource Name Description This informational text resource is intended to support reading in the content area. "Top Ten Things to Know About Stem Cell Treatments": A Plant Enemy's Enemy: The reading passage is a Top Ten list by the International Society for Stem Cell Research intended to educate the general public about the myths and realities of stem cell treatments. This informational text resource is intended to support reading in the content area. Did you know that plants call for help when insects attack them? Well...not really, but they do release a chemical odor which "calls for help" to the predators of plant-eating insects in order to fend off an attack. Scientists have developed strategies that utilize this mechanism to help protect agricultural plants from pests. This resource is intended to support reading in the content area. Scientists have discovered that animal cells can communicate by Animal Cells Can Communicate by Reaching Out and Touching, UCSF Team sending out thin Discovers: tubes of cytoplasm called cytonemes that extend across many cells to reach a cell that will receive the signal, much like neuron communication. This informational text resource is intended to support reading in the content area. This article describes the components of blood (red blood Blood Does a Body Good: cells, white blood cells, platelets, and plasma) including their functions and origins, along with a novel medical application for the rare blood- Blood Made Suitable For All: Body's Immune System Kills Mutant Cells Daily: producing stem cells. This informational text resource is intended to support reading in the content area. The text explains how blood is classified into types based on the presence of antigens. It describes a process whereby antigens can be removed by an enzyme to make all blood types the same as the universal donor. This informational text resource is intended to support reading in the content area. This article explores how scientists discovered that the immune system naturally suppresses cancer while they were researching how B cells change during the growth of lymphoma. The text explains how T cells work as an Born During a Drought: Bad News for Baboons: "immune surveillance" and can be a way of preventing blood cancers. Through experimentation, scientists discovered how vitally important those cells are to possibly suppressing other forms of cancer in the future. This informational text resource is designed to support reading in the content area. The article discusses how a drought affected the savanna ecosystem found in southern Kenya during 2009. It further addresses how baboons are affected later in life based on the conditions when they are born and the social status they are born into. Based on the research on baboons, the implications on human health are discussed in Cholera: Tracking the First Truly Global Disease: the latter portion of the article. This informational text resource is intended to support reading in the content area. The article describes London in the mid-19th century as a filthy, foul place for an everincreasing population as families relocated to the city hoping for work. Open reservoirs and use of the nearby Thames for raw sewage disposal was commonplace. Outbreaks of disease thrived in these environments but no causal association was made until Dr. John Snow hypothesized that cholera was transmitted by contaminated food or water. He mapped cholera deaths to sources of contaminated water, ultimately Cholera-Like Disease 'Piggybacking' on El Nino to Reach New Shores: Clue to How the Circulatory System is Wired: leading to improved sanitation and public health. This informational text resource is designed to support reading in the content area. The article discusses the research conducted by scientists showing the correlation between El Niño events and the spread of infectious disease. The article discusses how the scientists believe Vibrio bacteria are being transported across the ocean and the impact this can have on public health. This informational text resource is intended to support reading in the content area. The text describes the discovery of an enzyme’s role in blood vessel growth and development. Deploying the Body's Army: Ebola, Dengue Fever, Lyme Disease: The Growing Economic Cost of Infectious Diseases: The enzyme may be essential for advances in cancer research. This informational text resource is intended to support reading in the content area. Scientists have been making breakthroughs in immunotherapy: the use of infectious pathogens as a method for treating cancer. The infections heighten the response of the immune system and eradicate the cancer in the process. This informational text resource is designed to support reading in the content area. The article discusses the rise of pandemic disease outbreaks across the globe and how these outbreaks can affect world economies. The article further describes how economic Ecologists Identify Potential New Sources of Ebola and Other Filoviruses: Feeding Birds in Your Local Park? If They're White Ibises in Florida, Think Twice: models were used to assess different strategies on their effectiveness. The strategy of identifying the underlying cause of the emerging disease was considered to be most costeffective and beneficial longterm. This informational text resource is designed to support reading in the content area. The article discusses the research conducted by scientists who used machine learning methods to identify bats that were likely to be reservoirs for filoviruses. Scientists mapped out the geographical ranges of these bats and hope to be able to use this information to prevent future outbreaks. This informational Field Fever, Harvest Fever, Rat Catcher's Yellows: Leptospirosis by Any Name Is a Serious Disease: text resource is designed to support reading in the content area. The text describes the interactions between local wildlife (white ibises in Florida) and humans, and the impact that these interactions have on both species. The article presents both benefits as well as potential drawbacks to the close proximity of humans and white ibises. The article also describes how scientists are studying these interactions and their effects. This informational text resource is intended to support reading in the content area. The text describes current research into the factors that increase the rate of transmission of the bacterial disease Gut Reaction: Digestion Revealed in 3-D: Leptospirosis. Scientists are using research to provide tools to prevent future transmission. Scientists are studying three communities in Chile and determining what factors in each setting are contributing to the spread of the disease. This informational text resource is designed to support reading in the content area. The article describes how villi in the small intestine and muscle contraction work together to digest food and provide nutrients to the body, using the metaphor of coral working with an ocean current to circulate nutrients in the sea. A team of scientists plans to use technology to create 3-D imaging of digestion, and How Cells Take Out the Trash: How Plants Evolved to Cope with Cold: How the Ingenious Mushroom Creates Its Own Microclimate: their research is described in the article along with the specific physiology and function of the villi within the digestive tract. This informational text resource is designed to support reading in the content area. The text focuses on cellular waste and describes different ways a cell gets rid of waste. The text also briefly addresses how further study of the ways cells dispose of waste could lead to new approaches for preventing or treating disease. This informational text is intended to support reading in the content area. The article reports on recent research into the evolution of plants in cold climates. This informational Immune System: text resource is intended to support reading in the content area. The article explains the mushroom's ability to make its own microclimate. Through convection caused by the release of water vapor, mushrooms can efficiently disperse spores. This informational text resource is intended to support reading in the content area. The immune system's job is to defend against pathogens and keep our bodies healthy. There are a number of cell types, tissues, and organs that play a role in the immune process. The article discusses the three types of immunity: innate, adaptive, and passive. Finally, the article discusses various immune system disorders and diseases that are associated with each one. This informational text resource is intended to support reading in the content area. Metastasis Stem Cells in Blood of Breast Cancer Patients Discovered: New Problem Linked to 'Jet Lag': Science Daily posted a summary of a research study originally published in Germany about how metastasis stem cells were found in the blood of breast cancer patients. This resource is intended to support reading in the content area. Scientists have discovered that when they disrupt waking and sleeping times in mice, their immune systems responded in a harmful way causing disease, asthma, allergies and maybe even immune disorders. New Role Identified for Scars at the Site of Injured Spinal Cord: NIH Launches Early-stage Yellow Fever Vaccine Trial: Recent research funded by the National Institutes of Health points to scar tissue being beneficial to nerve regrowth in spinal injury. Previously it was believed scar tissue prevented nerve regrowth, but this new research shows that astrocyte scars may actually be required for repair and regrowth following spinal cord injury. This informational text resource is intended to support reading in the content area. The article discusses how yellow fever is becoming a health threat once again in parts of Africa and why it is necessary for a new vaccine for yellow fever to be developed. The article further discusses the process and experimental Nobel Goes for Studying "School Buses" in Cells: Phrenology-History of a Science and Pseudoscience: trials by which the vaccine is being tested for its effectiveness as well as its safety. This informational text resource is intended to support reading in the content area. The article describes the research of the three scientists sharing the 2013 Nobel Prize in physiology. The scientists studied how cells use vesicles to move materials like “school buses.” This informational text resource is intended to support reading in the content area. This article discusses phrenology, which is a pseudoscience that claims to be able to use bumps on human skulls to make inferences about personality traits. The article details why phrenology Plant Detectives Dig into How Cells Grow: Rabies Could Spread to Peru's Coast by 2020: is not a true science, and reviews the history of phrenology, the role of phrenology in the debate about the organization of the brain, how phrenology came under scientific criticism, and modern iterations of the technique. This informational text resource is intended to support reading in the content area. Moss is being used as a model system that may hold the key to understanding how all plant and animal cells grow. This article shows how a deeper understanding of cell growth is being established: specifically, how the cytoskeleton directs growth. This informational text resource is designed to Researchers Make a Key Discovery in How Malaria Evades the Immune System: support reading in the content area. The article discusses how the rabies virus is likely to spread to the coast of Peru by the year 2020. It further discusses the technology used to determine that the male vampire bat is most likely the carrier of the rabies virus to different areas in Peru. This informational text resource is designed to support reading in the content area. The article discusses the research conducted by scientists to determine how the malaria parasite evades the human immune system and enters into red blood cells. It was determined the parasite is able to use the complement system to its own advantage rather than Researchers Turn Brains Transparent By Sucking Out the Fat: Scientists Discover How Blue and Green Clays Kill Bacteria: being negatively affected by it. This informational text resource is intended to support reading in the content area. This brief (659 word) illustrated article describes the accomplishment at Stanford University of a pair of researchers who rendered a mouse brain transparent by removing the fat molecules in the cell membranes. This informational text resource is designed to support reading in the content area. This text describes how researchers unearthed a natural clay deposit with antibacterial characteristics. The text also discusses exactly how the two elements in the clay cause the destruction of the bacteria. The end of the article addresses how this discovery could provide possible solutions to bacteria that are antibioticresistant, like MRSA. This informational text is intended to support reading in the content area. The text Scientists Discover Important Mechanism in Plant Cells Which Regulates describes a Direction Plant Cells Grow: discovery scientists have made regarding a mechanism that regulates the direction in which plants grow. This informational text resource is designed to support reading in the content area. The text describes current research into the mosquitoes that Seeking Zika: Where and When Will Zika-Carrying Mosquitoes Strike Next?: carry the Zika virus, with the ultimate goal of using the research to predict and possibly prevent future outbreaks. Scientists are studying three Strange but True: The Largest Organism on Earth is a Fungus: towns in Ecuador by collecting data to help them discover the socioeconomic and environmental factors that put people most at risk for diseases carried by the Aedes aegypti mosquito, including the Zika virus. The scientists are also examining how virus transmission by these mosquitoes may be affected by climate change. This informational text resource is intended to support reading in the content area. This article details the discovery of the world's largest living organism, a humongous fungus in eastern Oregon. The text discusses the fungus itself, other sprawling fungi, and possible explanations for why such large Swine Flu Goes Global: The Human Immune System and Infectious Disease: sizes might be the norm for fungi. Also, the article describes the research methods scientists employed in order to determine that the fungus was in fact one single living organism. This informational text resource is intended to support reading in the content area. This article is about the swine flu. It explains where and how the virus originated, what countries it can be found in, facts about the virus, and whether a vaccine might be developed. This informational text resource is intended to support reading in the content area. The text explains the importance and function of the human immune system with a detailed The Microbiome: When Good Bugs Go Bad: discussion of non-specific versus specific immunity. The text features an embedded animated component showing how vaccines work. This informational text resource is intended to support reading in the content area. The text describes current research being conducted on microbiota and the immune system. The text describes how bacteria, or the lack of bacteria, play a role in the immune system and keep autoimmune diseases at bay. There is currently a spike in autoimmune diseases like Crohn's disease and psoriasis that occur primarily in developed countries. This research emphasizes how important our symbiotic The Mystery of Human Blood Types: relationship is with bacteria. This informational text resource is intended to support reading in the content area. Blood types such as the ABO group have been inherited for at least 20 million years. Despite how ancient blood groups are, scientists are still unclear as to their purpose. The ABO blood group, the most well-known of the blood groups, has enabled scientists to understand a link between blood groups and the immune system; discoveries over the last century suggest a link between blood groups and disease. Even with these findings, scientists are still unclear as to why such blood antigens The Real-Life Neuroscience Behind Zombies: Vaccines: Who Is at Risk for Heart Disease?: evolved in the first place. This informational text resource is intended to support reading in the content area. This text discusses the possible real-life brain disorders that could contribute to fictional zombie behavior. There is also a TED Talk video that explains these disorders further. This informational text resource is intended to support reading in the content area. This text explains how the immune system works and how vaccines, by mimicking natural infections, capitalize on the functions of the immune system. This informational text resource is designed to support reading in the content Wildlife Species Provide Clues to Spread of Antibiotic Resistance in Africa: area. The text, written by the National Institutes of Health, describes the many risk factors for heart disease. The text is broken into three areas: risk factors that can be controlled (like smoking, high blood pressure, and obesity), risk factors that cannot be controlled (like age and family history), and emerging risk factors. The informational text resource describes how researchers from Virginia Tech and the University of Sydney tested for resistance to 10 antibiotics among 18 wildlife species and cattle in Botswana. The results from the tests showed that antibiotic resistance is being transferred to mostly World Cup Raises Epidemic Questions: carnivores at the top of the food web. Animals that show multidrug resistance are crocodiles, leopards, hyenas, hippos, baboons, and warthogs. There also seems to be a correlation to drug resistance and aquatic life, but only certain species. Further research should be conducted in order to understand how the resistance moves across landscapes. This informational text resource is intended to support reading in the content area. Tropical areas such as Brazil can be hotspots for communicable diseases due to warm temperatures and crowded urban spaces. There is a concern that when Brazil hosts the World Cup, mosquitoborne dengue fever may Zika's Accidental Ally: Miami's Luxury High-Rises: spread to its visitors. The article explores methods of pathogen transfer in a variety of venues (pilgrimages, airplanes, cruise lines) and compares these to conditions at the World Cup. This informational text resource is designed to support reading in the content area. The article discusses the problems that are being encountered in Miami Beach as health officials try to execute a mosquito management program. Because of the high rise buildings, the pesticides being sprayed are not necessarily reaching the intended areas. Not only are mosquitoes staying alive, but they may become resistant to the firstchoice pesticides being used against them. Lesson Plan Name A New Vaccine for Yellow Fever?: An Activity on Factors Affecting Blood Flow: Animal vs. Plant & Prokaryotic vs. Eukaryotic Cells: Description This informational text resource from the National Institutes of Health is designed to support reading in the content area. The article discusses how yellow fever is becoming a health threat once again in parts of Africa and why it is necessary for a new vaccine against yellow fever to be developed. The article further discusses in detail the processes and experimental trials by which the vaccine will be tested for its effectiveness and its safety.  The lesson plan includes a note-taking guide, textdependent questions, a writing prompt, answer keys, and a writing rubric. This lesson is designed to explore the relationship between pressure and vessel diameter and to create a model that represents how high blood pressure may affect weakened vessels. A collaborative work of Melvin Flores, Larie Laudato and Glenn Soltes This lesson will develop students' ability to identify Antibiotic Resistant Wildlife?: Astrocytes Got Your Back: similarities and differences between animal and plant cells as well as prokaryotic and eukaryotic cells. In this lesson, students will analyze an informational text intended to support reading in the content area. The article addresses the possibility that antibiotic resistance is spreading through ecosystems in Botswana because resistance in humans has been shared with many other organisms. Researchers found that antibiotic resistance is significantly higher in water-associated species and carnivores. Scientists believe they can use this information to increase their understanding of why and how species are becoming antibioticresistant, with the end goal of stopping the spread of antibiotic resistance in humans. The lesson plan includes a note-taking guide, text-dependent questions, a writing prompt, answer keys, and a writing rubric. Numerous options to extend the lesson are also included. In this lesson, students will analyze an informational text intended to support reading in the content area.  The article presents exciting new research findings regarding axon generation in scar tissue formation following spinal cord injury.  Astrocytes were once thought to decrease the growth of new axon connections, but now these important cells have been shown to actually stimulate growth and connections in the neural network. The lesson plan includes a note-taking guide, text-dependent questions, a writing prompt, answer keys, and a writing rubric. Numerous options to extend the lesson are also included. The lesson was developed to broaden students' understanding of the immune system and its role in the human body. Students will do investigations and apply vocabulary terms to realworld scenarios. Back to the Basics: Immunity and Response: Blood Flow: Note that students will complete the 5E cycle twice over the course of two days; please see the attached "Lesson Overview" document for a chronological outline of each day.  The lesson is design to describe the factors affecting blood flow through the cardiovascular system. The lesson uses the 5E model as an approach for students to become engaged, analytical and inquisitive Blood Flow Learning Stations: Blood flow: A student-centered inquiry: Blood: The Stuff of Life: in learning about the mechanism of blood flow and the importance of this in our body. In addition, the lesson engages the student to test variables that may affect blood flow. Students will visit stations that demonstrate each of the factors that affect blood flow through the cardiovascular system. This is set of related lessons including direct instruction, games, readings, small group work and an inquiry activity to model factors affecting the human circulatory system. The purpose of this lesson is to teach students about blood and its components while instilling an appreciation of its importance for survival. The lesson takes a step-bystep approach to determining the "recipe" for blood while introducing students to important laboratory techniques like centrifugation and microscopy, as well as some diseases of cell types found in blood. It also highlights the importance of donating blood by explaining basic physiological concepts and the blood donation procedure. There are no formal prerequisites, but students should be Brain Power: Brain Regions In Action: comfortable with converting weight units. The only materials needed are a calculator and paper, and it would be helpful to print the downloadable color PDF files of blood smear images. During the breaks, students are asked to estimate and then calculate the amount of blood in their body, identify cell types in a blood smear, and discuss the composition of blood with their neighbor. The lesson can be completed within a 50-minute class session. Students will learn the different regions and lobes of the brain by making a 3D model. After a lecture, students will work in groups to create concept maps to describe the structure of the brain and give everyday examples of the function of each part. This resource is aligned with required Biology EOC benchmark SC.912.L.14.26. This lesson plan goes beyond the content and can be used to reinforce understanding of the brain functions, not just location of the main brain regions. It may also be aligned to the Anatomy and Physiology standard. Brain Storm: Brain Trauma: Cell Membrane Structure and Function: Cell Structure : Cells Are Alive!: Cells: Taking out the Trash: This lesson is a series of short activities centering on the brain benchmark for the Biology I EOC. Students investigate how bicycle helmets protect the brain from forces related to sudden changes in motion. This resource includes hands-on-activities to familiarize students with the fluid mosaic model of the cell membrane and its function. This lesson will cover the cell structures of both prokaryotic and eukaryotic cells. This lesson plan guides the student to examine the reasoning behind each of the tenets of the cell theory. Students will explore the formulation of cell theory and why this fundamental principle is important to biology by watching a video, conducting their own research, and discussing ideas with their peers. In this lesson, students will analyze an informational text that addresses cellular waste. The article students will read explains the different ways a cell gets rid of waste, including how proteasomes and lysosomes break down cell waste. The article covers another method of letting the waste “pile up.― This informational text is designed to support reading in the content area. The lesson plan includes a note-taking guide, textdependent questions, a writing prompt, answer keys, and a writing rubric. This lesson introduces the basic forms of pathogens and how our bodies prevent and fight infection from them. It goes more in depth on the differences between active and passive Cover Your Mouth! An overview of disease spread and the immune immunity as well as the system.: differences in non specific and specific defenses. The students will actively role play the events of specific immunity as well as evaluate methods of maintaining individual and public health. This lesson uses a lecture, a 3D model, and worksheets to help Crossing the Barrier: students master the concept of molecular transport across the cell membrane. In this lesson student will keep a scientific notebook to relate the major structure of fungi to their functions. Students will Deadly Decomposition-Fungi: review several resources on fungi as well as conduct an investigation using yeast to compare its decomposition properties. The students will discover how the movement of Diffusion of Starch and Potato Osmosis: material occurs through the selectively permeable Digestion...in 3-D!: Disease Transmission Lab: cell membrane, a highly selective barrier. They will observe the processes of diffusion and osmosis, first in two teacher-led demonstrations, and then through two lab activities: the diffusion of starch molecules through a plastic bag and potato cores immersed in isotonic, hypotonic, and hypertonic solutions. Finally, students will connect this knowledge to how water moves in and out of a cell in different solutions. This informational text resource is intended to support reading in the content area. In this lesson, students will analyze an informational text that addresses innovative research to aid in the understanding of how the digestive system works. The text describes how the villi in the small intestine work with the contraction of the muscle wall to aid digestion and how a team of researchers are working together to create a 3-D model this process. The lesson plan includes a note-taking guide, textdependent questions, a writing prompt, answer keys, and a writing rubric. Options to extend the lesson are also included. A lesson designed to model how an infectious disease can be transmitted. Don't have Issues, Learn the Tissues!: Economics and Epidemiology: By Melvin Flores, Larie Laudato and Glenn Soltes This project lesson is designed to allow students to make personal connections between abstract art, photography, and histology of human tissues. As a brief introduction, students explore current topics in regenerative medicine and cutting-edge technology in medical sciences associated with disease treatment and amputee treatment. Students will get the opportunity to survey Impressionist area art and histology slides of tissues. Student presentations will be comprehensive and involve multiple levels of cognitive abilities. This lesson provides a unique way for cross-curricular and interdisciplinary teaching and learning opportunities. In this lesson, students will read an article from the National Science Foundation. The article discusses the rise of pandemic disease outbreaks across the globe and how these outbreaks can affect world economies. The article further describes how economic models were used to assess different strategies on their effectiveness. The strategy of identifying the Edible Brain: El Niño Can Spread Disease: underlying cause of emerging diseases was considered to be most cost-effective and beneficial long-term. This lesson is designed to support reading in the content area. The lesson plan includes a note-taking guide, a vocabulary handout, text-dependent questions, a writing prompt, answer keys, and a writing rubric. This resource gives students the opportunity to inquire about the major components of the human brain, research the major components of the brain and then create a yummy model of the brain. The variety of strategies presented in this resource keeps students engaged while learning to identify parts of the brain. In this lesson plan, students analyze an informational text intended to support reading in the content area. The article discusses new research conducted by scientists showing the correlation between El Niño events and the spread of waterborne infectious diseases. The article discusses how the scientists believe Vibrio bacteria are being transported across the ocean during El Niño events, and it discusses the impact this can have on public health. The lesson plan includes a note-taking guide, textdependent questions, a writing prompt, answer keys, and a writing rubric. Numerous options to extend the lesson are also included. Finding the Sources of Ebola and other Filoviruses: Flower Poetry:  In this lesson, students will analyze an informational text from Science Daily that discusses the research conducted by scientists who used machine learning methods to identify bats that were likely to be reservoirs for Ebola and other filoviruses. Scientists mapped out the geographical ranges of these bats and hope to be able to use this information to prevent future outbreaks.This informational text resource is intended to support reading in the content area. The lesson plan includes a vocabulary guide, textdependent questions, a writing prompt, answer keys, and a writing rubric. In this lesson, students will dissect a flower to explore the flower’s structures and their functions. Students will also observe the flowers, fruit and cones to discover the similarities and differences in their functions. Four Major Plant Groups: Getting Comfortable in My Own Skin : Green with Envy: Heart Disease: Are You at Risk?: HEART HEALTH: Students will explore, identify, and collaborate to find and gain a better understanding of the four major plant groups. Students will investigate the integumentary system by predicting lesson topic in an engaging and creative manner, create a foldable of the 7 different layers of skin, and discuss the art of tattoos and which layer of skin is actually inked when going under the needle. Students will make recommendations for dealing with the effects of algal blooms with regard to public health. In this lesson, students will analyze an informational text by the National Institutes of Health that addresses the risk factors for heart disease. The text is broken into three areas: risk factors that can be controlled (like smoking, high blood pressure, and obesity), risk factors that cannot be controlled (like age and family history), and emerging risk factors. This lesson plan is designed to support reading in the content area. The lesson plan includes a note-taking guide, textdependent questions, a writing prompt, answer keys, and a writing rubric. This MEA is designed to educate students about the Heart Rate Activity: Body Positions and Physical Activity: Here's Your Sign! An Interactive Analogous View of the Cell: Hijacking the Immune System: relationship between fast food choices and heart health. It should give students dietary choices to assist in the prevention of high blood pressure and heart disease. This is a activity that should be used after a full introduction/lesson for the cardiovascular and circulatory system has been completed. Students should be able to determine how physical body changes affect the heart rate and blood flow. This two-part lesson will help students to be able to identify the major organelles of plant and animal cells, and enables them to understand correlations between the organelles' structure and how that aids in function. Students will be able to compare and contrast plant and animal cells. The first part of the lesson allows the class to interact together through a game of Jeopardy style questions regarding these two major types of cell types. The second portion of the lesson has students created an illustrated analogy of a cell to something that they are more familiar with, such as their school. In this lesson, students will analyze an informational text intended to support reading in the content area. Homeostasis in Motion: Houston, We Have A Brain Problem: Neurological Disorders and Where They Occur In the Brain: How are Prokaryotic and Eukaryotic Cells Alike and Different?: The article discusses new research conducted by Penn State scientists to determine how the malaria parasite is evading the human immune system and entering into red blood cells. The study revealed how the parasite is able to use the complement system to its own advantage rather than being negatively affected by it. This lesson plan includes a note-taking guide, text-dependent questions, a writing prompt, answer keys, and a writing rubric. Numerous options to extend the lesson are also included. Given dialysis tubing and glucose strips, students will be able to demonstrate how water molecules and other materials diffuse through the kidneys. Students learn about and diagram the major parts of the brain and where different neurological disorders occur. This lesson will help students to understand the structural differences between prokaryotic and eukaryotic cells. Students will independently read to gain background knowledge of the two types of cells. The class will be divided into groups to complete a poster that compares and contrasts Human Brain in 3D!: Immune System: Immune System Responses to Pathogens and Vaccines : Immune System-History of an Epidemic: Infectious Diseases and the Immune System: Introduction to Muscle Physiology: prokaryotes and eukaryotes. In this lesson, students will explore the major structural regions of the human brain and associate them with particular behaviors or functions. Students will identify the major parts of the immune system, including specific and nonspecific immune response, vaccines, and antibiotics. With this lesson students will explore immune responses to a pathogen attack and/or a vaccine with a didactic, kinesthetic model of the process. Students will learn about the immune system and how disease can affect personal and public health. The lesson is design to explain the basic functions of the human immune system, including specific and nonspecific immune response, vaccines, and antibiotics. Primarily, it focuses on infectious diseases and how the immune system defend the body against infectious diseases. The lesson uses the 5E model as an approach for students to become engage, analytical and inquisitive in learning about infectious diseases and the immune system. This is an introductory exercise for a section on muscle physiology. It Investigating Cell Theory through Observation, Testing, and Modeling: consists of a worksheet that can be used in any one of a number of teaching/learning styles. It is intended as a formative assessment and is the first in a series. Extra credit/extension questions are included at the end for advanced students. A PowerPoint show version is also included if the teacher chooses to use guided discussion with the entire class; some extra resources and background information are included in the PowerPoint. Teacher's versions of the worksheet and PowerPoint are included with answers (worksheet) and extra background information and commentary (PowerPoint). The author's intent is to have a series of activities related to all three standards on muscle physiology. Students will address the three main tenets of cell theory by investigating: (1) "How big is a cell?" (using virtual scaling and compound microscope skills); (2) "What do cells do?" (students will build a model of a cell using craft materials); and (3) "Where do new cells come from?" (interpreting evidence from graphs and making new predictions). This lesson would work well paired with a review on what constitutes a It's Just a Leaf: Journey into the Brain: Just Be Passive: scientific theory and student practice of using compound microscopes. Students will explore the role and function of the leaf and its microscopic structures by using a cross section of a lilac leaf microscope slide. In this lesson, students view and discuss video segments from the PBS program The Human Spark as they learn about the human brain, including information about brain regions, brain activity and technologies used to explore the brain. In this lesson, students will design their own controlled experiment. The teacher introduces osmosis through a short Prezi, checking their understanding along the way by means of comprehension questions included in the presentation. Immediately after the introduction, the teacher will place students into three or four groups and facilitate a brainstorming process in which students work together to develop questions, list materials and outline procedures. These will then be peer reviewed by their classmates in which they will give them recommendations and or offer suggestions. The Killer Clay!: Killer Microbe: Leptospirosis: A Serious Disease: teacher will make the final approval and experiments will commence the following class. Students will then report their results as a written lab report or using the same lab report format to create a gallery walk. This lesson is designed to support reading in the content area. In this lesson, students will analyze an informational text that addresses innovative research to aid in the understanding of how certain clays can be responsible for the killing of some bacterial pathogens. The lesson plan includes a note-taking guide, text-dependent questions, a writing prompt, answer keys, and a writing rubric. A lesson about the important topic of antibiotic-resistant bacteria with student activities and A/V resources. In this lesson, students will analyze an informational text intended to support reading in the content area. The NSF article describes current research into the transmission of the bacterial disease leptospirosis, with the ultimate goal of using the research to prevent future outbreaks. The article highlights the environmental conditions Let's Explore the Cell Theory!: Magnificent Microscope Tradeoffs MEA: Major Parts of the Brain: Marketing for the National Blood Pressure Association: that increase the transmission of the disease. The lesson plan includes text-dependent questions with an answer key, a writing prompt with a sample response, and a writing rubric. Students will explore the cell theory. Over the course of the lesson, students will examine the major parts of the cell theory and learn about the scientists who were involved in its development. Students will learn about the four types of microscopes (compound, dissection, transmission electron, and scanning electron) and compare them using the Model Eliciting Activity, or MEA, approach. Students act as a materials selection committee who will help a teacher decide which type(s) of microscopes are best suited for his classroom. This is a whole class internet lesson on the major parts and their functions of the brain. It includes the the lobe of the cerebrum, cerebellum, and the brainstem; midbrain, pons, and medulla oblongata. This MEA supports reading in the content area. Students create a model that the client can use to Mathematics of Microscopy: Microscope Basics: Modeling Kidney Dialysis: Mosquitoes in Miami: rank treatments for hypertension (high blood pressure) to choose the subject of their marketing campaign. After measuring the "field of view" of your microscope, your students can estimate the size of objects with this calculation. Students will learn microscope basics including parts of a compound light microscope, different types of microscopes, and how microscopes work. This lesson includes a 4-day plan that has students label the parts of a microscope with the teacher, in a group, and using a microscope. The students will also complete a presentation on a specific type of microscope. This activity will have you look at transport of molecules in and out of membranes in a different way by modeling kidney dialysis. Students should complete the Solution Problems Worksheet before beginning the Kidney Dialysis activity. In this lesson, students will analyze an informational text intended to support reading in the content area. The National Geographic article discusses the problems facing Miami Beach as health officials try to execute a mosquito management program to combat Zika. Because of the high rise buildings, the pesticides being sprayed are not reaching the intended areas. Another concern is that mosquitoes may become resistant to the first choice pesticides being used against them. This lesson is designed to support reading in the content area. The lesson plan includes a note-taking guide, text-dependent questions, a writing prompt, answer keys, and a writing rubric. Movement Across the Membrane: Red Rover: Non-specific and Specific Immune System explained:  Using the familiar children's game "Red Rover," students will simulate the selectively permeable cell membrane and model how various molecules can/can not cross with/without assistance. ResourceID: 28153 This lesson covers the information on the basic functions of the human non-specific and specific immune response. It does not cover the vaccines, health or antibiotics used as an approach to aid the immune system. There is vocabulary that goes as high as AP Biology. The lessons are editable so you can change Of Mice and Memory - Brain Anatomy Activity: Overview of the Nervous System : Pandemic Flu: Parts of the Brain: vocabulary if you would like to bring the lesson down to lower levels. However, higher level vocabulary is not too extraneous and I leave it for my 9th grade Honors classes. A PBS NOVA Classroom Activity with related video that models the brain and extends the learning to application of understanding how Alzheimers' disease impacts the brain. This lesson gives an overview of the structure and function of the central and peripheral nervous systems. Students participate in a ball toss exercise, during which they identify which division of the nervous system produces particular responses. After, students complete a worksheet on which they label the functions of each part of the nervous system. In this lesson, students will model an avian-human flu virus structure, replication, and spread. The accompanying PBS NOVA movie Pandemic Flu regarding H5N1 Avian and Swine Flu highlights interactions between the virus, humans, and birds. Students will learn about the parts of the brain by investigating digital resources. This lesson Pathogens in the Room: Pathogens, Diseases, and Vaccines: centers around the Glog Brain Parts. In this lesson, students will research pathogens to explain the significance of pathogenic agents for their health and the community. It aims to clear up common misconceptions about pathogens and the diseases they cause. Students will be assigned a pathogen and then conduct research to accurately describe the disease it causes. This lesson introduces different types of pathogens and how they cause disease in humans. It introduces and/or reinforces prior knowledge of active and passive immunity as well as the differences in non specific and specific defenses. Students will be introduced to how a vaccine works in the individual as well as the community to create immunity to a pathogen. The students will research different pathogens, the diseases they cause, the vaccines that have been developed for them, and how these vaccines protect individual as well as public health. The students will then compose a position paper on mandatory vaccinations for school children. Photomicrography of Wet Mounts of Hibiscus Plant Parts & pH Determination of Their Extracts: Plant Energy: Plant Similes: This structured inquiry lesson deals mainly on the preparation of crosssection wet-mounts of the Hibiscus stem, leaf and flower, and their photomicrography. Additionally, students will prepare the extracts of the Hibiscus stem, leaf, and flower, and determine their pH using the Hydrion (pH paper) and universal indicator. This lesson will allow the students to confirm the microscopic structures of the Hibiscus plant parts that could be observed through the photomicrographs, and infer on the chemical nature (acid, base, or neutral) of the plant extract depending on the determined pH values. In this lesson, students will explore the roles of roots and leaves in the process of photosynthesis with hands-on activity and a real world case of an exception in the plant kingdom. Students will compare and contrast the roles of roots and leaves in photosynthesis and relate it with the plant Rafflesia. Students will review the unit on the standard SC.912.L.14.7 (relate the structure of each of the major plant organs and tissues to physiological processes) by using Magical Squares. They then will create similes for plants, plaNTS, PLANTS: Plasmolysis in Plant Cells: Prokaryote and Eukaryote Microscope Activity: Seeking the Zika Virus: the major plant organs and tissues and their physiological processes. Students will explore the growth and development of plants by growing their own plants and documenting growth and development of major plant organs. Students will also create their own slides to observe and define the role meristematic tissue in the growth of plants. This a inquiry investigates plasmolysis in plant cells when exposed to NaCl solution. The ionic solution causes the water within the cell to move out and the cell membrane shrinks inward. Students will prepare wet mount slides, view, draw, record time data for plasmolysis, and analyze the data generated. This activity incorporates the use of microscopes to show actual cells that are examples of both eukaryotes and prokaryotes. In this lesson, students will read an informational text from the National Science Foundation. The text describes current research into the mosquitoes that carry the Zika virus, with the ultimate goal of using the research to predict and possibly prevent future outbreaks. Scientists are studying three towns in Small Cells verses Large Cells: Social Cells: Ecuador by collecting data to help them discover the socioeconomic and environmental factors that put people most at risk for diseases carried by the Aedes aegypti mosquito, including the Zika virus. The scientists are also examining how virus transmission by these mosquitoes may be affected by climate change. This lesson is designed to support reading in the content area. The lesson plan includes text-dependent questions with an answer key, a writing prompt with a sample response, and a writing rubric. The students will have an opportunity to discover that the size of cells (surface area and volume) has a major impact on the movement of nutrients and waste products in and out through the cell by diffusion across the semipermeable membrane. The movement of these molecules is essential for the health of the cell and to maintain homeostasis. This is an interactive activity for the students to learn about the different types of cells and which cell parts exist in them. It will develop the students' ability to identify similarities and differences between the various types of cells by engaging all Spirillum, Dandelions, and Koalas, OH MY!: T Rex Blood?: The Black Death Epidemic: three learning styles: visual, auditory, and tactile. This lesson allows students to create a science center display showing their knowledge of the general structures of prokaryotic and eukaryotic cells and the structures and functions for the components of plant and animal cells. At the end of this lesson, students will be assessed by participating in a gallery walk that displays their design for a local science center. This lesson is a STEM project-based learning opportunity. A PBS Nova Podcast/Video with accompanying activities that introduce and explore paleontology and the geologic timescale through analysis of fossil bones. Students will research the history of the Black Death and learn about the causative pathogen involved through a POGIL activity. There will be suggested web-links for the students to research what is currently known about the disease and questions for them to answer as a teaching method and evaluation. As a final assessment, the students will construct an epidemiological triangle in pairs and then share with the class. This video was conceived around the idea that students, particularly those not in AP-level classes, have a practical application for knowing about the major divisions between plants, particularly about the details of plant anatomy and reproduction. My objectives for this lesson are as follows: The Case of the Stolen Painting: A Forensic Mystery: Students will be able to identify the major evolutionary innovations that separate plant divisions, and classify plants as belonging to one of those divisions based on phenotypic differences in plants. Students will be able to classify plants by their pollen dispersal methods using pollen dispersal mapping, and justify the location of a "crime scene" using map analysis. Extension: Students will be able to analyze and present their analysis of banding patterns from DNA fingerprinting done using plants in a forensic context. The Cell Theory Lesson Plan: For the lesson, students will need to be familiar with the idea that living things are related, that these relationships are part of organisms' evolutionary history; that there are types of plants; and that DNA can be used to establish similarities and differences between individuals and species. It will also be helpful for them to know that increased genetic diversity will increase a species' likelihood of survival. The lesson will take approximately 135 minutes (one 90 period, one 45 minute period), with some material assigned as homework. Materials needed: Paper, writing utensils, color printing is ideal. The components that make up the Cell Theory will be discussed, and students will show understanding by writing a detailed paragraph in their own words explaining the three components. They will then work in small groups to research historical events leading to the development of the theory by numerous scientist, the dates of their contributions, and explain how each contribution increased the development of the Cell Theory. The Cell Theory Sharing Book: The Dangers of Sticky Blood: Students will then independently report their findings by constructing a colorful detailed timeline. The time line will show the historical events leading to the development of the cell theory in a chronology order. Using their timeline they will revisit the one-paragraph summary of the cell theory and rewrite the paper to explain how the sequence of events leading to the development of the cell theory in a Chronology order demonstrates the true nature of science as we know it today. In this lesson, students will create a picture book about the cell theory to be shared with middle school students who are learning about this topic and to demonstrate the relationship between the development and the process of science. Students will research the dangers of high blood cholesterol levels in humans. The prevention of high cholesterol and lowering of high cholesterol to improve health of individuals will be presented in an informative online newsletter. The newsletters The Drama of Glucose Regulation: The Importance of a Baboon's Birthday: will be utilized to raise community awareness of the issue within the school by printing out the final products and displaying them in the school hallway. The online tool Smore will be used for constructing the newsletter and can be shared on social media to reach those that are not in the school community. Students will act out glucose metabolism - from the blood stream to cells where they will be converted to ATP, with help from insulin. In this lesson, students will read an article from the National Science Foundation that discusses how a drought affected the savannas of southern Kenya during 2009. It further addresses how baboons are affected later in life based on when they are born and the social status they are born into. Based on the research on baboons, the implications on human health are also discussed in the latter portion of the article. This lesson is designed to support reading in the content area. The lesson plan includes a note-taking guide, text-dependent questions, a writing prompt, answer keys, and a writing rubric. The Lungs and Ventilation Activities: The Making of a Marvel: Part 2: The Nerve Cell: It's All About Connection: This is a series of activities designed to enable students to visualize the causes of air movement in and out of the lungs. This second lesson in human reproduction systems discusses our dependency on hormones for reproductive processes to occur. I will outline the production and release of eggs according to hormone levels and the production of sperm. Students will compare and contrast male and female gamete production. Students will also identify patterns of key female reproductive hormones in their association with the menstrual cycle. This lesson provides a description of the anatomy and physiology of the nerve cell/neuron. Vocabulary words, diagrams of the nerve cell, and the steps of nerve conduction are presented in this lesson. This lesson also includes a hands-on activity for making and edible nerve cell, group discussion, group activities, diagram worksheets, sentence completion worksheets, and assessments that require written responses from the students to describe how nerve cells transmit information from one cell to another. The Spread of Rabies in Peru: The Structures of the Respiratory System: The Three Lines of Defense!: In this lesson plan, students will analyze an informational text intended to support reading in the content area. The article explains how the rabies virus is likely to spread from the interior of Peru to its coast by the year 2020.  It further discusses the technology used to determine that the male vampire bat is most likely the carrier of the rabies virus to different areas in Peru.  The lesson plan includes a vocabulary guide, textdependent questions, a writing prompt, answer keys, and a writing rubric.  This lesson covers the basic anatomy of the human respiratory system. Through visualization and repetition, the students will learn and will understand the anatomy of the respiratory system. This lesson is a good introduction to the immune system. It will give students the chance to have discussions with the teacher and classmates as well. The teacher will also have a chance to quickly assess the students' knowledge by using checkpoint questions scattered throughout the PowerPoint presentation. After the lesson is complete, the students will This is not Heart to Learn: Three "M"s: Models, Microscopy, and Measurement!: have a clear understanding of the three lines of defense and nonspecific and specific immune responses. This lesson is about the heart and how it functions. The student will be able to diagram the flow of blood through the heart. The student will also be able to demonstrate how blood pressure is measured and how it can change under various physiological conditions. During this unit of discovery, teachers will encourage students in grades 9-10 to explore the world of microscopy. Throughout these 4-5 class periods, the student should discover the structures, functions, and usage of the various parts of the compound light microscope as well as how to measure specimens using a scientific model. If the extension is selected, the students will additionally discover the mathematical skills needed to compute specimen size, area of the field of view, and total magnification. Students will explore the importance of microscopy to promote their own understanding of microscopic life and cellular function. An additional homework extension allows students to create individual blogs Touring the Cell: Tracing the Development of the Cell Theory: Tracking a Virus: Transport Across a Membrane: Understanding the process of transpiration: Water, Water, Where Did You Go?: using key terms and review each other's blogs in a round-robin manner. In this lesson the students will provide detailed explanations of cell structures and their functions, produce an artifact that highlights how prokaryote and eukaryote cells differ, how plant and animal cells differ, and how structure relates to function. Students will also design and conduct a lab exploring cells and/or their structures. This lesson will help the students to understand the cell, the cell theory and the scientists who contributed to the development of the cell theory. Simulation of an outbreak of an infectious disease using colorimetric reagents to identify the source. In this activity students will investigate how and under what conditions molecules move across the cell membrane. This lesson is intended to provide student with an introduction to the process of transpiration. The goal is to help students understand the process of transpiration and the role that this process plays in plant physiology. This lesson plan explains the principle of osmosis in plant tissues. It is designed for three class periods, Water's Journey: What's so major about your brain?: What's Your Type?: each 50 minutes in length, and one take-home activity. Students will compare and contrast osmotic potential of different plant tissues given through an investigation. The teacher explains and presents the content and the procedures on the first day as a lesson walk through. The investigative lab attached help the students to explore and relate the concept of osmosis in real life. This lesson takes students through a series of observations that will allow students to explore waters path through hand grown plants, examine xylem in celery, and observe stomata from slides they create. Students will interact with a brain model and apply the major areas of the brain to the locations within their own head. In this lesson, students will analyze an informational text intended to support reading in the content area.The article explains the advancements that scientists have made in understanding blood types. By reading and synthesizing the text, students will explore a real-world example of how scientific knowledge becomes more robust and When Good Bugs Go Bad: Where in the Brain?: White Ibis: A Feathered Cujo: durable through investigations. This lesson includes a note-taking guide, text-dependent questions, a writing prompt, answer keys, and a writing rubric. In this lesson, students will analyze an informational text that addresses research into the fine balance between microbes and their hosts. The text explains how a human's microbiota or microbiome plays a very important role in the immune system. The text describes how bacteria, or the lack of bacteria, play a role in the immune system and keep autoimmune diseases at bay. This lesson is designed to support reading in the content area. The lesson plan includes a note-taking guide, textdependent questions, a writing prompt, answer keys, and a writing rubric. This lesson is focused on specific parts of the brain and their functions. Students will be able to look at specific parts of the brain and provide an example of a behavior it controls. In this lesson, students will analyze an informational text that describes the impact that local ibises have on their environment Who's your cell mate?: Why do plants eat bugs? An Investigation of Carnivorous Plant Structures: and the impact that humans have on the birds. The study examines how humans are changing the lifestyles of white ibises, which in turn causes the interactions between birds and humans to lead to a greater spread of disease. The author analyzes the positive and negative effects of interactions between organisms in an ecosystem. The lesson plan includes a text coding strategy, text-dependent questions, a writing prompt, sample answer keys, and a writing rubric. Numerous options to extend the lesson are also included. During the lesson students will review parts of the plant and animal cell and build upon that knowledge by studying organelle function more closely. This is a plant structure and function internet research based lesson. Carnivorous plant structure and function modifications are used compare to the structure and functions of the major organs and tissues of noncarnivorous plants. Internet and student computers are required for this lesson. A carnivorous plant specimen (pitcher plant preferred) and a noncarnivorous plant specimen in the classroom Your Brain, In Living Color: is highly recommended for increased student interest. This activity implements a web resource to teach students the major parts of the brain and a some functions. It is an interactive site and can be adapted to fit any classroom. Video/Audio/Animation Name A Tour of the Cell: AIDS: Evolution of an Epidemic: BioVisions - The Inner Life of a Cell: Description Paul Anderson takes you on a tour of the cell. He starts by explaining the difference between prokaryotic and eukaryotic cells. He also explains why cells are small but not infinitely small. He also explains how the organelles work together in a similar fashion. This Howard Hughes Medical Institute Holiday Lecture Series video includes 6, 60-minute lectures on the history of the AIDS epidemic. The talk covers AIDS/HIV history in the United States from the 1980's through 2007 (when the lecture was taped) and also some basics on the biology of HIV and AIDS, including transmission, viral replication and the human immune system. The video offers a useful perspective on an example of the evolution of scientific thinking and research, as researchers discuss the development of scientific theories about HIV/AIDS as well as treatments. Several related resources, such as animations and video clips, can be found on the main page. In this narrated animation, we get a look at the inner workings and signals within and around cells. Leukocytes are used as the example. Lipid bilayer membranes are shown from the perspectives of outside the cell and inside the cell. The Bozeman Science: A Tour of the Cell: Cheetah Anatomy for Running: Desert Biome: Endosymbiosis: Endosymbiosis: Cyanobacteria to Chloroplast : Kidney Function: dynamics and roles of signal transduction, cytoskeleton structures and functions, interactions between organelles and the cytoskeleton, centrioles, the nuclear envelope, mRNA translation, protein synthesis and transport, the endoplasmic reticulum, and the Golgi apparatus are all shown as leukocyte extravasation occurs in response to inflammation. This is a very clear, thorough, easy to understand video on cells. It includes the history of the microscope, types of microscopes, future microscope technology, and how they all work. The majority of the video is a comparison/contrast of prokaryotic and eukaryotic cells, including size, structure and function of the organelles in a eukaryotic cell. This video highlights cheetah adaptations that allow for successful hunting using speed. Includes commentary from cheetah researchers. This video segment from NOVA: "A Desert Place" details the behaviors and habitats of some of the Sonoran Desert's creatures, focusing on the adaptations they use to survive in one of the most extreme environments in the world. Paul Andersen explains how eukaryotic cells were formed through a process of endosymbiosis. He describes how aerobic bacteria became mitochondria and cyanobacteria became chloroplasts. He mentions an example of symbiosis that occurs today and mentions the importance of Dr. Lynn Margulis in the development of this modern theory. Video explaining endosymbiosis, using the evolution of the chloroplast. This video presentation is illustrating the amount of work the kidney performs each day to maintain proper levels of ions in the body. It will help in Lobe-Oratorium: increasing your understanding about the functions of kidney. This interactive game provides students with examples of the functions the different lobes of the brain are responsible for Students learn how the different parts of the brain work This Protein Purification video lesson is intended to give students some insight into the process and tools that scientists and engineers use to explore proteins. It is designed to extend the knowledge of students who are already somewhat sophisticated and who have a good understanding of basic biology. The question that motivates this lesson is, "what makes two cell types different?" and this question is posed in several ways. Such scientific reasoning raises the experimental question: how could you study just a subset of specialized proteins that distinguish one cell type from another? Two techniques useful in this regard are considered in the lesson. This video lesson will easily fit into a 50MIT BLOSSOMS - Methods for Protein Purification: minute class period, and prerequisites include a good understanding of cellular components (DNA vs. Protein vs. lipid) and some understanding of the physical features of proteins (charge, size etc). The simple cell model used here can be assembled in any kind of container and with any components of different solubility, density, charge etc. In-class activities during the video breaks include discussions, careful observations, and the use of a "very simple cell" model to explore two techniques of protein purification. Students and teachers can spend additional time discussing and exploring the question of "how we know what we know" since this lesson lends itself to the teaching of the process of science as well. Movement Through a Plant: Plant Structure: Test Your Science IQ: Cells: The Skeletal System Rap Song: Transport Across the Cell Membrane: Zebrafish Heart Regeneration: Tutorial The cohesion-tension theory describes how fluids move up the xylem to the leaves of a tree. With this tutorial learners will understand how water moves through a plant. Absorption and transpiration work together with cohesion and tension to move fluids from the soil, through the roots, and up through the tops of the tree. Paul Andersen explains the major plants structures. He starts with a brief discussion of monocot and dicot plants. He then describes the three main tissues in plants; dermal, ground and vascular. He also describes the plant cells within each of these tissues; epidermis, parenchyma, collenchyma, sclerencyma, xylem and phloem. A collection of questions that tests students' knowledge about cells Educational hip-hop video reviewing the human skeletal system. Paul Andersen describes how cells move materials across the cell membrane. All movement can be classified as passive or active. Passive transport, like diffusion, requires no energy as particles move along their gradient. Active transport requires additional energy as particles move against their gradient. This video presentation will help to understand the regeneration process in a zebrafish. When the zebrafish heart is damaged, the wound site is rapidly sealed with a fibrin clot that stems bleeding within seconds. Following clot formation, the tissue that surrounds the heart muscle, the epicardium, gradually covers the fibrin clot via migration and cell division. Over the next few months, new cardiac muscle is produced and replaces the clot. Name Action Potentials and Muscle Contraction: Active Transport and the Sodium-Potassium Exchange Pump: Allergy Immune Response: Description This tutorial will help you to visualize and understand how nerve impulses cause muscle contractions. The neurons and muscle tissue conduct electrical current by moving ions across cellular membranes. The signal will travel through the tissue and trigger the contraction of individual sarcomeres, the functional units of muscle. This tutorial explains the neuromuscular junction where the synapse occurs. This tutorial will help you to understand the process of active transport. Sodium and potassium ions are pumped in opposite directions across the membrane building up a chemical and electrical gradient for each. This tutorial will help you to understand how allergies develop. Allergies are exaggerated immune responses caused by B cells producing excess IgE antibodies. An allergen (food, dust) is a foreign substance, which binds to the antibodies and triggers a reaction that includes the production of histamine. Alveolar Pressure Changes During Inspiration and Expiration: Anatomy of a Muscle Cell: Anatomy of a Neuron: B Lymphocytes: This challenging tutorial addresses the concept at a very high level of complexity. This tutorial helps you to understand the factors involved in air flow into and out of the lungs. This challenging tutorial addresses the concept at a high level of complexity. This Khan Academy video describes the structure of muscle cells. The tutorial details the muscle cell from the macro skeletal muscle to the individual cell of the muscle, called the myofiber. The functions of actin and myosin and how they cause muscles to contract are also explained. This Khan Academy video describes the anatomical structure of a neuron. Each structure is explained in detail. This Khan Academy video describes B lymphocyte cells, and how they are activated Bacteria: Baroreceptor Reflex Control of Blood Pressure: Bone Growth : and produce antibodies within the immune system. This video from the Khan Academy introduces the symbiotic relationship between the many bacteria that live inside the human body. The basics of bacteria structure, reproduction, and bacterial infections are discussed. Blood pressure is determined by the force of the blood acting on the walls of the blood vessels. Two factors determine the size of this force. One is the volume of blood being pumped through the vessel. The other is the size of the vessels. Changes in blood pressure can be caused by either a change in the amount of blood being pumped or by a change in the size of the blood vessels. Feedback mechanisms, described in this animation, will alter heart rate and blood vessel dilation to maintain blood pressure at appropriate levels. This tutorial will help you to understand how bone growth is different from the Bone Strength: Cell Anatomy: growth of many other organs. Although bone may appear to be rigid and lifeless it is actually living tissue that is capable of growth. Unlike soft tissues, bone cannot simply grow by adding additional cells and removing cells that are no longer necessary. The calcium laid down in bone gives the skeleton the strength and rigidity needed to protect and support the body. This rigidity means that expansion requires addition of cells on the outside and, when necessary, the removal of calcium and other materials on the inside. This tutorial will help you to understand which factors determine the strength of bone. Bone strength is determined by the internal structure, shape, and size of the bone. As we age, bone mass is lost, leading to a common condition called osteoporosis. This tutorial compares normal bone tissue with osteoporotic bone tissue. This tutorial will help the learners to learn about the anatomy of Cell Membrane Function: Cell Membrane Proteins: Cell Structure and Function: the cell. As the learners move the cursor over each cell organelle, they are shown information about that organelle's structure and function. This tutorial will help you to understand how a molecule can be transported across a membrane against a concentration gradient. Cellular membranes function to keep the internal environment of the cell distinct from the external environment. Concentrations of many molecules differ across cellular membranes. This animation shows the function of the sodium potassium pump. Students will learn about the different types of proteins found in the cell membrane while viewing this Khan Academy tutorial video. This tutorial is a basic unit on cellular biology. The unit introduces the cell theory and its parts. It also discusses the importance of microscopes while studying cells. This presentation describes animal and plant cells in detail and discusses Cells Through Different Microscopes: Cells vs. Virus: A Battle for Health: Cellular Transport: the organelles found in each. This tutorial will help the learner visualize how a cell or single celled organism can differ in its view when looked at under different magnifications and different types of microscopes. This tutorial can be used by the teacher as an added resource for their lesson about different microscopes and how they work.. All living things are made of cells. In the human body, these highly efficient units are protected by layer upon layer of defense against icky invaders like the cold virus. Shannon Stiles takes a journey into the cell, introducing the microscopic arsenal of weapons and warriors that play a role in the battle for your health. Cellular transport refers to the movement of compounds across the outer wall or membrane of the cell. This tutorial will help the learners better understand the different types of transport that occur across a membrane barrier. Cerebral Blood Supply: Part 1: Cerebral Blood Supply: Part 2: Changes in Alveolar Pressure During Breathing: Changes in the Partial Pressure of Oxygen and Carbon Dioxide in Blood: Chemical Digestion: In this Khan Academy video tutorial, learn the main important arteries in the brain that bring necessary oxygen to all parts of the brain. In this Khan Academy tutorial video, learn about the arteries that serve your brain. This is a continuation from Cerebral Blood Supply: Part 1. This tutorial will help students understand how the difference in the alveloar pressure and the barometric air pressure allows the inspiration and expiration of air in the lungs. This tutorial will help you to understand how the exchange of gases between the alveoli and the blood occurs by simple diffusion due to the changes in the partial pressure of oxygen and carbon dioxide. This challenging tutorial addresses the concept at a high level of complexity. Tissues associated with the stomach produce not only digestive enzymes but also hydrochloric acid. The hydrochloric acid helps to chemically break down the food in the stomach. This tutorial will help you to understand how digestive tissue can produce a concentrated acid without damage to cells and molecules exposed to the acid. Chemical Synapse: Chemoreceptor Reflex Control of Blood Pressure: This challenging tutorial addresses the concept at a high level of complexity. This tutorial explains that electrical signals cannot travel from one neuron to the next directly. The signal crosses the synapse in chemical form. One neuron releases chemicals in response to an action potential and the chemicals travel across the synapse and stimulate an action potential in the next neuron. These chemicals are called neurotransmitters. This tutorial will help students to understand how concentrations of gases in the blood change during breathing. This animation shows high carbon dioxide concentrations and low oxygen concentrations indicating that gas exchage is occurring at a slower than ideal rate. Because of Complications After a Heart Attack (Myocardial Infarction): Conducting System of the Heart: Cytotoxic T Cells: Cytotoxic T-Cell Activity Against Target Cells: this, heart rate increases or decreases to compensate the exchange of gas. Learn about the complications that may occur after a heart attack (myocardial infarction). This tutorial will help you to understand how all of the components of the heart are able to work together without direct control from the central nervous system. This video shows that for proper function of the heartbeat, it is necessary that all of the muscle fibers in a region contract in unison. This Khan Academy video explains how cytotoxic t cells get activated by MHC-I antigen complexes and then proceed to kill infected cells. This video addresses the concept at a high level of complexity. One of the functions of the T-Cells in the immune system is to attack and destroy infected cells. Target cells are cells that have been attacked by a virus. When the target cells have been taken over by a virus and they do not have a good chance of surviving, they trigger their own death. This action reduces the chance that other nearby cells will become infected. Diagnosing Strokes by History and Physical Exam: Diffusion and Osmosis: Gas Exchange During Respiration: Gas Exchange During Respiration: Healing after a Heart Attack (Myocardial Infarction): Heart Anatomical Structure: This challenging tutorial addresses the concept at a high level of complexity. Learn how strokes are often diagnosed. This Khan Academy tutorial guides you through the processes of diffusion and osmosis while explaining the vocabulary and terminology involved in detail. This tutorial is helpful in understanding how the exchange of oxygen and carbon dioxide takes place during the process of respiration. This tutorial explains the exchange of oxygen and carbon dioxide within the respiratory system. Learn about the process your body goes through in healing after a heart attack (myocardial infarction). This tutorial will help the learners to understand the anatomical structure of Helper T Cells: Hemoglobin Breakdown: Hormonal Communication: the heart. Students will learn the function of the parts of the heart in order to attain better understanding of the heart's role in the human body. This Khan Academy video discusses helper t cells in the immune system. The role of helper t cells in activating b cells is detailed. This challenging tutorial addresses the concept at a high level of complexity. This tutorial will help you to understand the processing of hemoglobin and why it is different from the processing of many other macromolecules. Hemoglobin contains a heme group which contains iron. Iron is not common in other macromolecules therefore conservation of iron is important and is processed independently. Hormones are produced in the endocrine glands and are released in the blood stream. This tutorial will help the learners to understand how the hormones reach their target cells in order to Hormones and Gastric Secretion: How Do Hormones Interact with the Nervous System?: How do you know if someone is having a stroke? Think FAST!: How Does the Ear Detect Sound Waves?: How Osmosis Works: communicate the message. This tutorial will help you to understand why the secretion of gastric fluids is controlled both locally and through the central nervous system. This animation describes how gastric secretion is regulated by both the brain and digestive hormones. This tutorial will help you to understand how hormones interact with the nervous system. The central nervous system can directly release hormones or it can signal tissues throughtout the body to release hormones. Learn a system to quickly identify if a person is having/has had a stroke using the FAST components. This tutorial will help you to understand what determines the range of sound frequencies a person can hear. Sound travels through the air and through water as waves of changing pressure. The volume of sound is determined by the amplitude of the sound waves. This tutorial will help you to understand how the concentration of How the Heart Actually Pumps Blood: Hydrochloric Acid Production of the Stomach: molecules in solution in water can cause the movement of water across a membrane which is also known as osmosis. Preventing the loss or gain of too much water through osmosis is often an important challenge for cells. This TED ED original lesson takes a closer look at how the heart pumps blood. For most of history, scientists weren’t quite sure why our hearts were beating or even what purpose they served. Eventually, we realized that these thumping organs serve the vital task of pumping clean blood throughout the body. But how? Edmond Hui investigates how it all works by taking a closer look at the heart’s highly efficient ventricle system. This tutorial will help you to understand how digestive tissue can produce a concentrated acid without damage to cells and molecules that are exposed to the acid. Hydrochloric acid production is described in this animation. This challenging tutorial addresses the concept at a high level of complexity. Hypersensitivity Type 2 and Blood Types: Infectious Evidence: Introduction to the Cell Membrane: Hypersensitivity refers to excessive, undesirable reactions produced by the normal immune system. Type 2 hypersensitivity is also known as cytotoxic hypersensitivity and may affect a variety of organs and tissues. This animation relates hypersensitivity and blood types together. Click "View Site" to open a full-screen version. This tutorial is designed to help secondary science teachers learn how to integrate literacy skills within their science curriculum. This tutorial focuses on using specific textual evidence to support students’ responses as they analyze science texts. The focus on literacy across content areas is designed to help students independently build knowledge in different disciplines through reading and writing. This Khan Academy tutorial addresses the importance of the phospholipid bilayer in the structure of the cell membrane. The types Introduction to the Endocrine System: Mechanism of Steroid Hormone Action: Metabolic Process Location: Mineral Transport in Plants: of molecules that can diffuse through the cell membrane are also discussed. This Khan Academy video tutorial describes the basics of the endocrine system and the role of hormones as the communicators of the body. The major endocrine glands and the hormones that they produce are explained. This tutorial will help you to understand how hormones influence the growth and development of organisms. This tutorial will help the learners to understand the functions and metabolic processes carried out by various organs involved in metabolism. Metabolic processes are not evenly shared between the different organs and tissues in the body. In fact, the cells of these different organs and tissues often specialize in aspects of catabolism, biosynthesis, and regulation. This tutorial will help you to understand how minerals are absorbed by the root hair in plants. Movement of Oxygen and Carbon Dioxide: This tutorial will help you to understand how the movement of oxygen and carbon dioxide takes place between the alveoli and the blood by taking partial pressure into consideration. Oxygen diffuses from the air through the alveoli into the blood and carbon dioxide diffuses from the blood into the alveoli. This occurs due to differences in partial pressures. This challenging tutorial addresses the concept at a high level of complexity. Muscle Contraction: This tutorial will help students understand the process of muscle contraction. A muscle contains many muscle fibers and each fiber contains a bundle of 420 myofibrils. Each fibril is striated and these striations are produced by the arrangement of thick and thin filaments, called actin and myosin. The contraction and relaxation of these actin and myosin filaments help muscles move. Myosin and Actin: Nerve Impulse Transmission: Nutrional Value of Food Using a Bomb Calorimeter: Organs of Digestion: This Khan Academy video describes how the proteins myosin and actin interact to produce a mechanical force on muscles, allowing them to move. The transmission of a nerve impulse along a neuron from one end to the other occurs as a result of electrical changes across the membrane of the neuron. This tutorial will help students to visualize and understand the transmission of a nerve impulse. This tutorial will help you to understand how the nutritional value of food can be measured on many different scales. The most basic measurement scale is the free energy content in the food, i.e., how much energy is released when chemical bonds within the food are broken. This tutorial explores the steps that food takes on its journey through the digestive system. All major digestive organs and the process of nutrient absorption are explained. Parts of the Cell: Phagocytosis: Post Stroke Inflammation: Prokaryotes, Eukaryotes, & Viruses Tutorial: Proton Pump: This Khan Academy tutorial describes the differences between prokaryotic and eukaryotic cells. It then goes on to discuss in detail the structures and their functions found in the eukaryotic cell. This tutorial will help you to understand the function of phagocytes. Phagocytes are specialized cells that ingest and break down foreign material including bacteria and viruses. This challenging tutorial addresses the concept at a high level of complexity. Learn about poststroke inflammation. This a mostly text resource that provides accurate, straightforward descriptions of prokaryotes, eukaryotes, and viruses. It could be a great tool to help students compare and contrast organisms with each other and viruses, or a good review passage. This tutorial will help you to understand how a concentration gradient across a membrane is used. When a molecule or an ion is moved across a membrane from an area of low concentration to an area of high concentration then a gradient is generated. This gradient can be chemical or it can also create a difference in electrical charge across the membrane if ions are involved. The proton pump generates an electrical and chemical gradient that can be used to create ATP which can drive a large number of different biochemical reactions. Reflex Arc: Regulated Secretion: This tutorial will help students to understand the process of reflex arc. A reflex arc is the nerve pathway which makes a fast, automatic response possible.When the safety of an organism demands a very quick response, the signals may be passed directly from a sensory neuron, via a relay neuron, to a motor neuron for instant, unthinking action. This is a reflex action. This online tutorial will help you to understand the process of regulated secretion. Risk Factors for Coronary Artery Disease: Risk Factors for Stroke: Role of Phagocytosis in Nonspecific Immunity: Secondary Active Transport in the Nephron: In regulated secretion, proteins are secreted from a cell in large amounts when a specific signal is detected by the cell. The specific example used in this tutorial is the release of insulin after a glucose signal enters a pancreatic beta cell. Learn about the risk factors for coronary artery disease including modifiable and non-modifiable risk factors. In this Khan Academy video you will learn some of the modifiable and non-modifiable risk factors that can lead to a stroke. This Khan Academy video describes non specific immunity, and the specific role of phagocytes. The tutorial explains how phagocytes engulf pathogens that enter the body as a line of defense. This Khan Academy video discusses which ions are allowed to be actively transported out of the filtrate of urine. The process of secondary active transport in the nephron is described in detail. Sensory Systems in Plants: Signal Molecules of the Endocrine System: This tutorial will help you to understand phytochromes in plants and how they affect plant growth. Phytochromes are pigment containing proteins that play an important role in plant regulation, including the germination of seeds. This tutorial demonstrates how the structure of a signal molecule determines its function. Signal molecules can interact with either intracellular or extracellular receptors. For a signal molecule to bind with an intracellular receptor it must be able to pass through the cellular membrane. Generally signal molecules that enter the cell are nonpolar and fat soluble. These signal molecules can pass through the lipid bilayer of the cell membrane. Signals that bind with extracellular receptors are proteins or other types of molecules that cannot readily pass through the membrane. This challenging tutorial addresses the Signal Transduction: Sodium Potassium Exchange Pump: Sound: T-Cell Dependent Antigens: concept at a high level of complexity. The human body consists of a wide variety of cell types that must work together to sustain the life of an organism. They must respond to their environment and communicate with each other in a process called signal transduction. This tutorial will help the learners understand the process of signal transduction. This tutorial will help you to understand how sodium and potassium ions are pumped in opposite directions across a membrane building up a chemical and electrical gradient for each. These gradients can be used to drive other transport processes. This tutorial provides information about the sound and how it travels. It also includes information on the anatomy and physiology of the human ear for the learners to understand how sound passes through the ear. T-cells perform a wide variety of functions in the immune system. In this tutorial you will The Cardiac Cycle: The Circulatory System and the Heart: The Immune Response: The Lungs and Pulmonary System: The Nerve Impulse: understand the structure and function of the T-cells. The cardiac cycle is defined as the complete heartbeat from generation to the beginning of the next beat, and includes the diastole, the systole, and the intervening pause. This tutorial will help you to understand the cardiac cycle. This Khan Academy video explains the major vessels involved in the flow of blood and follows the steps that blood takes as it travels through the heart. This tutorial will help students understand how the immune system of vertebrates is characterized by acquired responses that are highly specific to particular antigens. This system has the advantage of having a cellular memory for previous infections. This Khan Academy video discusses form and function in the respiratory system. All of the respiratory organs are discussed. This tutorial explains that the source of the impulse The Role of Vitamins in Human Nutrition: Three Phases of Gastric Secretion: in a neuron is a rapid change in the polarity of the cell membrane in a restricted area. The direction of the electrical gradient is rapidly reversed and then returns to normal. The change in charge stimulates the process to happen in adjacent parts of the cell and the change in the polarity travels down the neuron. This tutorial will help you to understand the role that vitamins play in human nutrition. Vitamins interact with enzymes to allow them to function more effectively. Though vitamins are not consumed in metabolism, they are vital for the process of metabolism to occur. This challenging tutorial addresses the concept at a high level of complexity. This tutorial will help students understand how food is digested with the help of different gastric secretions. Gastric juice from glands renders food particles soluble, initiates digestion, and converts the gastric contents to a semiliquid mass called chyme, thus Treatment of Stroke with Interventions: Tropomyosin and Troponin and Their Role in Muscle Contraction: Types of Immune Responses: Vaccine and Active Immunity: preparing it for futher disgestion in the small intestine. In this Khan academy video tutorial, learn about the possible treatments and interventions of different types of strokes. This Khan Academy video explains the role that tropomyosin and tropinin play in muscle contraction. The role of the calcium ion concentrations are also explained. This challenging tutorial addresses the concept at a high level of complexity. This Khan Academy video contains an overview of the types of immune responses in the body. The differences between humoral adaptive immunity and cell mediated immunity are discussed in detail. A vaccine allows a person to develop acquired immunity against an illness without actually getting the disease. This interactive tutorial will help the learners to understand the process by which vaccines work in the human body. Virus: Voltage-Gated Channels and the Action Potential: Water Transport in Plants: What Causes Antibiotic Resistance?: This tutorial will help the student understand about viruses which are small infectious agents that replicate only inside the living cells of other organisms. This tutorial explains how a charge is generated across a membrane. The function and role of the voltage-gated sodium ion channel and voltage-gated potassium ion channel are explained in detail. This tutorial will help you to understand how plant cells intake water. This animation shows how water is transported from the root systems of plants upwards to the leaves. This short video describes the process of antibiotic resistance. Right now, you are inhabited by trillions of micro organisms. Many of these bacteria are harmless (or even helpful!), but there are a few strains of ‘super bacteria’ that are pretty nasty -- and they’re growing resistant to our antibiotics. Why is this happening? Kevin Wu details the What Causes Zombies?: What is a Stroke?: evolution of this problem that presents a big challenge for the future of medicine. This tutorial is designed to help secondary science teachers learn how to integrate literacy skills within their curriculum. This tutorial focuses on evaluating the reasoning and evidence of an argumentative claim. The focus on literacy across content areas is designed to help students independently build knowledge in different disciplines through reading and writing. Learn the conditions present in your brain that cause a stroke. Original Tutorial Name Alternation of Generations in Plants: Brain Basics: Description Explore the alternation of generations in plants to see how sporophytes and gametophytes relate to each other during the life cycle of mosses and lilies. The brain isn’t just one big blob sitting in your head, it’s actually divided into many distinct parts. By the end of this tutorial you should be able to name the Cell Types: Cells, Cells Everywhere!: Cellular Transport: The Role of the Cell Membrane: Challenges to Public Health : major regions of the brain and identify them on a diagram. Cell Types Learn how to identify explicit evidence and understand implicit meaning in the basic principles of the cell theory. The cell theory states that all organisms are made of cells. These cells are the smallest and basic unit of life. And finally, cells can only come from other cells. In this tutorial, you will learn about the function of the cell membrane as a selective barrier that moves material into and out of the cell to maintain homeostasis. Learn to distinguish between public health issues and individual health issues in this interactive tutorial. Microscope Mathematics: This is part 1 of 4 in a series of tutorials addressing this standard. Learn how you can use a microscope as a tool to measure objects. Learn how to identify explicit evidence and understand implicit meaning in a text. Plant Organs: This tutorial is designed to help you learn the concepts and skills from Grades 9-12 Biology to relate the structure of each of the major plant organs and tissues to physiological processes. You will enhance your familiarity with the structure, function, and evolutionary origins of plant tissues and organs. By the end of this tutorial you should be able to identify the basic functions of the immune system. You will also be able The Immune System: Your Body’s Private Defense System: to distinguish between nonspecific and specific immune responses. Types of Microscopes: What Makes Your Blood Flow?: By the end of this tutorial, you should be able to determine differences and similarities of the structure and function of compound light microscopes, dissecting microscopes, scanning electron microscopes and transmitting electron microscopes. Learn about factors that affect the blood flow in your body in this interactive tutorial. Perspectives Video: Expert Name Birdsong Series: Statistical Analysis of Birdsong: Birdsong Series: Mathematically Modeling Birdsong: Blood Types Don't Mix: Bone Histology and Anatomy: Description Wei Wu discusses his statistical contributions to the Birdsong project which help to quantify the differences in the changes of the zebra finch's song. Richard Bertram discusses his mathematical modeling contribution to the Birdsong project that helps the progress of neuron and ion channel research. Learn how carbohydrates in our cells' membrane determine our blood types. Dr. Gregory Erickson explains bone histology and anatomy with special remarks on bones of a juvenile Tyrannosaurus rex. If you watch this video, your brain will be learning more about itself! Think about it. Dr. Tom Miller discusses the anatomy Carnivorous Plant Anatomy and Morphology: and morphology of carnivorous plants. Lots of issues causes disease Causes of Disease: genetics, lifestyle, pathogens - let's practice prevention when we can. Florida State researcher Jens Foell Chronic Pain and the Brain: discusses the use of fMRI and statistics in chronic pain. Dr. Erinn Muller explains research related to discovering coral genotypes Coral Genotype Assessment for Reef Restoration: capable of thriving despite environmental health challenges. Dr. Erinn Muller explains how coral health research at Mote Marine Coral Research Driving Florida Reef Restoration Policy: Laboratory is driving policy decisions regarding coral reef restoration in Florida. Jens Foell discusses how statistical noise reduction is used in fMRI brain imaging to be able to determine which fMRI, Phantom Limb Pain and Statistical Noise: specifics parts of the brain are related to certain activities and how this relates to patients that suffer from phantom limb pain. When you cut yourself, your body Homeostasis and Hemostasis: goes to work to prevent blood loss. A bio-mathematician discusses the Mathematical Patterns and Folds in the Brain: folds and the structure of the brain and how they relate to math. Scientists use microscopes to see what Modern Microscopy: is invisible to the naked eye. Strengthen your understanding of how Moving Muscle Filaments: muscle filaments function as this physiologist flexes his knowledge. Get mentally fit as this physiologist Muscle Fibers and Motor Units: explains muscle structure! Jens Foell discusses the link between PTSD: Correlation vs Causation: correlation and causation in PTSD patients. Brain Structures and their Functions: Rapid Genetic Testing of Seafood: Sensory Systems of Robots: Skeletal Muscle Physiology: Sorting Cells: Teaching About Blood Types Using Forensics: The Brain and Behaviors: The Brain and our 5 Senses: The Criminal Brain and Correlation vs. Causation: The Lymph System: The neurobiology of hearing, learning, and speaking: Understanding EKG: What's in Blood?: Who Are You Calling Birdbrain?: Dr. Mahmood Shivji explains how information contained in the DNA of seafood species is used for identification in the marketplace. Robots use "eyes" and "ears" to sense their surroundings, just like you and me. Get moving and learn how muscles move you! Flow Cytometry is a cool technology that can count and sort cells. CSI in the Classroom: Blood at a crime scene points to a suspect. Jens Foell discusses brain function as it relates to brain imaging technology such as fMRI. Our brains process all sensory information and tell the body what to do next. Florida State Researcher, Jens Foell, discusses the importance of understanding correlation versus causation when researching personality traits and criminal behavior. The lymph system gets some respect. Frank Johnson discusses the science behind hearing, learning, and speaking. Tanganyika Wilder explains EKG. The importance of being a red blood cell. Rick Hyson discusses the neuroscience contribution to the Birdsong project. Perspectives Video: Professional/Enthusiast Name Blood Sucking Vampires: Description Dr. Michael Thornton discusses the nutritive value of blood - for vampires! Fitness and Cardiovascular Health: Fitness and the Brain: Growing Healthy Babies: Ins and Outs of Kidney Dialysis: What you need to know about exercising for your heart and lungs. Fire up those brains with exercise! Feeding your baby, inside and outside your body. When your kidneys fail you, there's help with kidney dialysis. Understanding human physiology will allow you to stand under your own power at the end of a long rowing trip. KROS Pacific Ocean Kayak Journey: Muscle Physiology: Related Resources: KROS Pacific Ocean Kayak Journey: GPS Data Set[.XLSX] KROS Pacific Ocean Kayak Journey: Path Visualization for Google Earth[.KML] Your kidneys work hard - show Love your kidneys!: them some respect! Dr. George Cohen discusses a variety of skin treatments that utilize Skin Radiation Technologies for Medical Therapy: electromagnetic radiation, including lasers, UV light, and x-rays. Virtual Manipulative Name Blood Typing: Cellular Transport: Description This virtual manipulative will provide the students with the opportunity to choose a correct blood type for the patients and administer blood transfusion. The students will have the chance to check the blood type before starting the transfusion. The knowledge and understanding of blood groups will also be tested during the activity. This activity will help the students to learn about the cellular transport which is referred as the movement of compounds across the outer wall or membrane of the cell. Students will recognize that the purpose of cell transport is to maintain homeostasis. While navigating this activity, students will gain a better understanding of the different types of transport that occurs across a membrane barrier, such as diffusion, osmosis, active and passive transports. The diabetic dog educational game is based on the discovery of the hormone insulin, which made it possible to treat the patients with diabetics. This activity will help the students to recognize some important facts about diabetes such as: Diabetic Dog Game: Electrocardiogram: what is the diabetes? what happens to the blood sugar level when some one has diabetes? what is insulin? what shall someone suffering form diabetes do if they have high blood sugar level? what shall someone suffering form diabetes do if they have low blood sugar levels? This educational game is based on the discovery of the electrocardiogram,(ECG). ECG is used for recording the small electric waves being generated during heart activity, a simple way of diagnosing heart conditions. This game lets the students explore the key elements of the electrocardiogram for measuring the heart beats and analyze the mountains and valleys in the ECG curve. Some of the sample learning goals can be: For what do we use ECG? Illustrating the process of diffusion : Interactive Animations: Cellular Transport: Interactive Cell Animations: Mapping the Brain: Megacell - The Cell and its Organelles Game: What does the mountains and valleys of the ECG curves stand for? What can you find out about the heart with an ECG? This virtual manipulative will help the students to understand that osmosis is the movement of water molecules from an area of high concentration across a semipermeable membrane to an area of low concentration. This illustration of the diffusion process will help the students to understand the concept of osmotic pressure which is created by the movement of the water based on their concentration gradient and thus resulting in the difference of the solute concentration. This animation offers an overview of membrane structure and demonstrates how the membrane acts as a highly selective barrier. Opportunities are provided to observe diffusion/osmosis, passive transport, and active transport in action. This is an online resource that uses interactive models for students to click on to learn about the cell. The visual representation will have students distinguish between animal and plant cells and also learn about the permeability of the cell membrane. This PBS virtual interaction allows students to map the brain using six different realistic virtual imaging techniques. Students are able to view color-coded regions of the brain and explanations of the functions of major brain parts are available as well. The Cell and its Organelles educational game is based on the 1974 Nobel Prize in Physiology or Medicine, which was awarded for discoveries concerning the structure and organization of the vital components of a cell. Students playing the game will learn what an ultracentrifuge is used for; what the names of the compartments of the cell are; and what functions the various organelles have in the cell. This interactive cell membrane simulation allows students to see how different types of channels allow particles to move through the membrane. Sample learning goals: Membrane Channel Simulations: Molecular Expressions: Introduction to microscopy: Nerve Signaling Game: Neuron: Predict when particles will move through the membrane and when they will not. Identify which particle type will diffuse depending on which type of channels are present. Predict the rate of diffusion based on the number and type of channels present. This site provides an introduction to microscopy and microscopes including history, images, and interactives. This game is based on several Novel Prizes in Physiology or Medicine from 1906 until today that have been awarded for discoveries related to nerve signaling. Student playing the game will learn... -How are nerve cells composed? -How do nerve cells carry the signals that coordinate all the activities in our body? -How has the research into neuroscience developed through the 20th century? In this simulation, you will explore how neurons conduct electrical impulses by using the action potential. This phenomenon is generated through the flow of positively charged ions across the neuronal membrane. Stimulate a neuron and monitor what happens. You can pause, rewind, and move forward in time in order to observe the ions as they move across the neuron membrane. Other ways to explore: Plant, Animal and Bacteria Cell Models: Signal Transduction: The Blood Typing Game: Describe why ions can or cannot move across neuron membranes. Identify leakage and gated channels, and describe the function of each. Describe how membrane permeability changes in terms of different types of channels in a neuron. Describe the sequence of events that generates an action potential. Living cells are divided into two types procaryotic and eucaryotic. This division is based on internal complexity. This website provides interactive graphic roadmaps to the organization of both of these cell types. It also shows distinctions between plant and animal cells. This interactive virtual manipulative will help the students in understanding how the wide variety of cell types work together to sustain the life of an organism. In this animation students will observe the complex biochemical process of how cells respond to their environment and communicate with each other in a process called signal transduction. This educational game is about blood types, blood typing, and blood transfusions. Your challenge is to save patients in urgent need of blood transfusions. Your job is to decide what blood type these patients belong to in order to administer safe blood transfusions. At the end you will be evaluated: if you make no mistakes at all you will get all five blood drops. In this game, you are a trainee soldier of the Immune System Defense Forces, defending a human against bacterial infection. You have two missions to complete. In this first, you must command a team of white blood cells The Immune System Game: called granulocytes to fight against bacteria invading the blood system through a finger wound. In the second mission, you must commond an army of macrophages and dendritic cells to fight the invading bacteria. This game explores the 1905 Nobel prize in Physiology or Medicine, which was awarded for investigations and discoveries concerning the disease tuberculosis or "TB." The game is a sort The Tuberculosis Experiments and Discoveries Game: of old fashioned laboratory simulation and allows students to discover and experience some of the classic methods used to detect whether a specific bacterium causes a disease. Vitamin B1: Chicken Farm Game: This fast-paced game relies on a keen knowledge of food containing vitamin B1. This game will help the students recognize the importance of vitamin B1, which food contains vitamin B1 and what is the disease beriberi. Perspectives Video: Teaching Idea Name Categorizing Plant Specimens: Easing into Evolution with Minimal Controversy!: Description Get outside and interact with nature after you watch this idea for teaching about the different parts of plants! This teacher has an approach to teaching evolution that may help to keep skeptical students engaged: start by teaching about plants, and then make small changes to the discussion over time. Get a tip for modeling the cell Learning Stations for Cell Transport: membrane in this lesson idea. Let this semipermiable Semipermiable Cell Membrane Inquiry: membrane teaching idea sink in. Your mind will swell with knowledge after submerging in Studying Cell Membranes and Osmosis with Hard-Boiled Eggs: this idea to demonstrate osmosis. Educational Game Name Description This cell structure crossword puzzle uses vocabulary from CELLS alive! If you have Cell Structure Crossword Puzzle: trouble and need a hint, use the "Search this Site" engine in the lefthand menu. Good Luck! This is a hands on experiment where simulates the way that an infection Some Similarities between the Spread of Infections and Growth Population: disease spread in a population and the similarities with growth population. Teaching Idea Name Egg Osmosis Lab: Description This lab is a hands on activity where students can explore the concepts of osmotic solutions and diffusion. It demonstrates all 3 osmotic solution types: isotonic, hypertonic, and hypotonic. It takes a duration of 4 days, but each day is approximately 15 minutes of a specific daily task. Osmosis Demonstration Lab: Students will use potato cores to demonstrate osmosis in salt solutions. Presentation/Slideshow Name Description A PowerPoint with speaker notes covering infectious Introduction to Infectious Diseases: diseases, causes, transmission, and control. Unit/Lesson Sequence Name Microscope Mania: Description A unit that can be used as a whole or in parts. Teaches the parts of a microscope as well as the concept of magnification through lab stations. Includes slideshow, worksheets, links and activities, review and quizzes. Problem-Solving Task Name Osmosis in Potatoes: Description In this lab exercise, students will demonstrate diffusion in potatoes by placing them into solutions of water and salt water. 3D Modeling Name Sickle Cell Hemoglobin: Description Sickle cell disease results from a single nucleotide mutation in a hemoglobin gene leading to an altered protein sequence and a different three dimensional shape. In this activity, students will assemble normal and sickle cell hemoglobin molecules and investigate what leads to an abnormal red blood cell in patients with the mutation. Worksheet Name The Biology Corner: Description This resource for biology teachers includes a lesson plan section which contains classroom activities, labs and worksheets. The activity sheets are categorized by Science and Literacy, Anatomy, Scientific Method, Cells, Phyla, Evolution and Taxonomy, Genetics, Ecology, and Plants. Project Name Transpirational Design Lab: Description This is an inquiry design lab for students to understand transpirational pull of plants. Like all inquiry labs, it is open for more designs than the one presented in the PowerPoint example. The example in the PowerPoint is the easiest to implement in the classroom. It requires a growlite (a bulb that produces the UV light plants need to grow), a fan, a light source with a 100 Watt bulb, Ziplock bags, rope, and plants that are the same (I use petunias). Student Resources Title Action Potentials and Muscle Contraction: Active Transport and the Sodium-Potassium Exchange Pump: Description This tutorial will help you to visualize and understand how nerve impulses cause muscle contractions. The neurons and muscle tissue conduct electrical current by moving ions across cellular membranes. The signal will travel through the tissue and trigger the contraction of individual sarcomeres, the functional units of muscle. This tutorial explains the neuromuscular junction where the synapse occurs. This tutorial will help you to understand the process of active transport. Sodium and potassium ions are pumped in opposite directions across the membrane building up a Allergy Immune Response: Alternation of Generations in Plants: Alveolar Pressure Changes During Inspiration and Expiration: Anatomy of a Muscle Cell: chemical and electrical gradient for each. This tutorial will help you to understand how allergies develop. Allergies are exaggerated immune responses caused by B cells producing excess IgE antibodies. An allergen (food, dust) is a foreign substance, which binds to the antibodies and triggers a reaction that includes the production of histamine. This challenging tutorial addresses the concept at a very high level of complexity. Explore the alternation of generations in plants to see how sporophytes and gametophytes relate to each other during the life cycle of mosses and lilies. This tutorial helps you to understand the factors involved in air flow into and out of the lungs. This challenging tutorial addresses the concept at a high level of complexity. This Khan Academy video describes the structure of muscle cells. The tutorial details the muscle cell from the macro skeletal muscle to the individual cell of the muscle, called the myofiber. The functions of actin and myosin and Anatomy of a Neuron: B Lymphocytes: Bacteria: Baroreceptor Reflex Control of Blood Pressure: how they cause muscles to contract are also explained. This Khan Academy video describes the anatomical structure of a neuron. Each structure is explained in detail. This Khan Academy video describes B lymphocyte cells, and how they are activated and produce antibodies within the immune system. This video from the Khan Academy introduces the symbiotic relationship between the many bacteria that live inside the human body. The basics of bacteria structure, reproduction, and bacterial infections are discussed. Blood pressure is determined by the force of the blood acting on the walls of the blood vessels. Two factors determine the size of this force. One is the volume of blood being pumped through the vessel. The other is the size of the vessels. Changes in blood pressure can be caused by either a change in the amount of blood being pumped or by a change in the size of the blood vessels. Feedback mechanisms, described in this animation, will alter heart rate and blood BioVisions - The Inner Life of a Cell: Blood Typing: vessel dilation to maintain blood pressure at appropriate levels. In this narrated animation, we get a look at the inner workings and signals within and around cells. Leukocytes are used as the example. Lipid bilayer membranes are shown from the perspectives of outside the cell and inside the cell. The dynamics and roles of signal transduction, cytoskeleton structures and functions, interactions between organelles and the cytoskeleton, centrioles, the nuclear envelope, mRNA translation, protein synthesis and transport, the endoplasmic reticulum, and the Golgi apparatus are all shown as leukocyte extravasation occurs in response to inflammation. This virtual manipulative will provide the students with the opportunity to choose a correct blood type for the patients and administer blood transfusion. The students will have the chance to check the blood type before starting the transfusion. The knowledge and understanding of blood Bone Growth : Bone Strength: Brain Basics: groups will also be tested during the activity. This tutorial will help you to understand how bone growth is different from the growth of many other organs. Although bone may appear to be rigid and lifeless it is actually living tissue that is capable of growth. Unlike soft tissues, bone cannot simply grow by adding additional cells and removing cells that are no longer necessary. The calcium laid down in bone gives the skeleton the strength and rigidity needed to protect and support the body. This rigidity means that expansion requires addition of cells on the outside and, when necessary, the removal of calcium and other materials on the inside. This tutorial will help you to understand which factors determine the strength of bone. Bone strength is determined by the internal structure, shape, and size of the bone. As we age, bone mass is lost, leading to a common condition called osteoporosis. This tutorial compares normal bone tissue with osteoporotic bone tissue. The brain isn’t just one big blob sitting in your head, it’s actually divided into many distinct parts. Cell Anatomy: Cell Membrane Function: Cell Membrane Proteins: Cell Structure and Function: By the end of this tutorial you should be able to name the major regions of the brain and identify them on a diagram. This tutorial will help the learners to learn about the anatomy of the cell. As the learners move the cursor over each cell organelle, they are shown information about that organelle's structure and function. This tutorial will help you to understand how a molecule can be transported across a membrane against a concentration gradient. Cellular membranes function to keep the internal environment of the cell distinct from the external environment. Concentrations of many molecules differ across cellular membranes. This animation shows the function of the sodium potassium pump. Students will learn about the different types of proteins found in the cell membrane while viewing this Khan Academy tutorial video. This tutorial is a basic unit on cellular biology. The unit introduces the cell theory and its parts. It also discusses the Cell Structure Crossword Puzzle: Cell Types: Cells Through Different Microscopes: Cells vs. Virus: A Battle for Health: importance of microscopes while studying cells. This presentation describes animal and plant cells in detail and discusses the organelles found in each. This cell structure crossword puzzle uses vocabulary from CELLS alive! If you have trouble and need a hint, use the "Search this Site" engine in the lefthand menu. Good Luck! Cell Types This tutorial will help the learner visualize how a cell or single celled organism can differ in its view when looked at under different magnifications and different types of microscopes. This tutorial can be used by the teacher as an added resource for their lesson about different microscopes and how they work.. All living things are made of cells. In the human body, these highly efficient units are protected by layer upon layer of defense against icky invaders like the cold virus. Shannon Stiles takes a journey into the cell, introducing the microscopic arsenal of weapons and warriors that play a role in the battle for your health. Cells, Cells Everywhere!: Cellular Transport: Cellular Transport: Learn how to identify explicit evidence and understand implicit meaning in the basic principles of the cell theory. The cell theory states that all organisms are made of cells. These cells are the smallest and basic unit of life. And finally, cells can only come from other cells. Cellular transport refers to the movement of compounds across the outer wall or membrane of the cell. This tutorial will help the learners better understand the different types of transport that occur across a membrane barrier. This activity will help the students to learn about the cellular transport which is referred as the movement of compounds across the outer wall or membrane of the cell. Students will recognize that the purpose of cell transport is to maintain homeostasis. While navigating this activity, students will gain a better understanding of the different types of transport that occurs across a membrane barrier, such as diffusion, osmosis, active and passive transports. Cellular Transport: The Role of the Cell Membrane: Cerebral Blood Supply: Part 1: Cerebral Blood Supply: Part 2: Challenges to Public Health : Changes in Alveolar Pressure During Breathing: Changes in the Partial Pressure of Oxygen and Carbon Dioxide in Blood: In this tutorial, you will learn about the function of the cell membrane as a selective barrier that moves material into and out of the cell to maintain homeostasis. In this Khan Academy video tutorial, learn the main important arteries in the brain that bring necessary oxygen to all parts of the brain. In this Khan Academy tutorial video, learn about the arteries that serve your brain. This is a continuation from Cerebral Blood Supply: Part 1. Learn to distinguish between public health issues and individual health issues in this interactive tutorial. This is part 1 of 4 in a series of tutorials addressing this standard. This tutorial will help students understand how the difference in the alveloar pressure and the barometric air pressure allows the inspiration and expiration of air in the lungs. This tutorial will help you to understand how the exchange of gases between the alveoli and the blood occurs by simple diffusion due to the changes in the partial pressure of oxygen and carbon dioxide. Cheetah Anatomy for Running: Chemical Digestion: Chemical Synapse: This challenging tutorial addresses the concept at a high level of complexity. This video highlights cheetah adaptations that allow for successful hunting using speed. Includes commentary from cheetah researchers. Tissues associated with the stomach produce not only digestive enzymes but also hydrochloric acid. The hydrochloric acid helps to chemically break down the food in the stomach. This tutorial will help you to understand how digestive tissue can produce a concentrated acid without damage to cells and molecules exposed to the acid. This challenging tutorial addresses the concept at a high level of complexity. This tutorial explains that electrical signals cannot travel from one neuron to the next directly. The signal crosses the synapse in chemical form. One neuron releases chemicals in response to an action potential and the chemicals travel across the synapse and stimulate an action potential in the next neuron. These Chemoreceptor Reflex Control of Blood Pressure: Complications After a Heart Attack (Myocardial Infarction): Conducting System of the Heart: Cytotoxic T Cells: chemicals are called neurotransmitters. This tutorial will help students to understand how concentrations of gases in the blood change during breathing. This animation shows high carbon dioxide concentrations and low oxygen concentrations indicating that gas exchage is occurring at a slower than ideal rate. Because of this, heart rate increases or decreases to compensate the exchange of gas. Learn about the complications that may occur after a heart attack (myocardial infarction). This tutorial will help you to understand how all of the components of the heart are able to work together without direct control from the central nervous system. This video shows that for proper function of the heartbeat, it is necessary that all of the muscle fibers in a region contract in unison. This Khan Academy video explains how cytotoxic t cells get activated by MHC-I antigen complexes and then proceed to kill infected cells. This video addresses the concept at a high level of complexity. Cytotoxic T-Cell Activity Against Target Cells: Desert Biome: Diabetic Dog Game: One of the functions of the T-Cells in the immune system is to attack and destroy infected cells. Target cells are cells that have been attacked by a virus. When the target cells have been taken over by a virus and they do not have a good chance of surviving, they trigger their own death. This action reduces the chance that other nearby cells will become infected. This challenging tutorial addresses the concept at a high level of complexity. This video segment from NOVA: "A Desert Place" details the behaviors and habitats of some of the Sonoran Desert's creatures, focusing on the adaptations they use to survive in one of the most extreme environments in the world. The diabetic dog educational game is based on the discovery of the hormone insulin, which made it possible to treat the patients with diabetics. This activity will help the students to recognize some important facts about diabetes such as: what is the diabetes? Diagnosing Strokes by History and Physical Exam: Diffusion and Osmosis: Electrocardiogram: what happens to the blood sugar level when some one has diabetes? what is insulin? what shall someone suffering form diabetes do if they have high blood sugar level? what shall someone suffering form diabetes do if they have low blood sugar levels? Learn how strokes are often diagnosed. This Khan Academy tutorial guides you through the processes of diffusion and osmosis while explaining the vocabulary and terminology involved in detail. This educational game is based on the discovery of the electrocardiogram,(ECG). ECG is used for recording the small electric waves being generated during heart activity, a simple way of diagnosing heart conditions. This game lets the students explore the key elements of the electrocardiogram for measuring the heart beats and analyze the mountains and valleys in the ECG curve. Some of the sample learning goals can be: Gas Exchange During Respiration: Gas Exchange During Respiration: Healing after a Heart Attack (Myocardial Infarction): Heart Anatomical Structure: Helper T Cells: For what do we use ECG? What does the mountains and valleys of the ECG curves stand for? What can you find out about the heart with an ECG? This tutorial is helpful in understanding how the exchange of oxygen and carbon dioxide takes place during the process of respiration. This tutorial explains the exchange of oxygen and carbon dioxide within the respiratory system. Learn about the process your body goes through in healing after a heart attack (myocardial infarction). This tutorial will help the learners to understand the anatomical structure of the heart. Students will learn the function of the parts of the heart in order to attain better understanding of the heart's role in the human body. This Khan Academy video discusses helper t cells in the immune system. The role of Hemoglobin Breakdown: Hormonal Communication: Hormones and Gastric Secretion: How Do Hormones Interact with the Nervous System?: helper t cells in activating b cells is detailed. This challenging tutorial addresses the concept at a high level of complexity. This tutorial will help you to understand the processing of hemoglobin and why it is different from the processing of many other macromolecules. Hemoglobin contains a heme group which contains iron. Iron is not common in other macromolecules therefore conservation of iron is important and is processed independently. Hormones are produced in the endocrine glands and are released in the blood stream. This tutorial will help the learners to understand how the hormones reach their target cells in order to communicate the message. This tutorial will help you to understand why the secretion of gastric fluids is controlled both locally and through the central nervous system. This animation describes how gastric secretion is regulated by both the brain and digestive hormones. This tutorial will help you to understand how hormones interact with the nervous system. The How do you know if someone is having a stroke? Think FAST!: How Does the Ear Detect Sound Waves?: How Osmosis Works: How the Heart Actually Pumps Blood: central nervous system can directly release hormones or it can signal tissues throughtout the body to release hormones. Learn a system to quickly identify if a person is having/has had a stroke using the FAST components. This tutorial will help you to understand what determines the range of sound frequencies a person can hear. Sound travels through the air and through water as waves of changing pressure. The volume of sound is determined by the amplitude of the sound waves. This tutorial will help you to understand how the concentration of molecules in solution in water can cause the movement of water across a membrane which is also known as osmosis. Preventing the loss or gain of too much water through osmosis is often an important challenge for cells. This TED ED original lesson takes a closer look at how the heart pumps blood. For most of history, scientists weren’t quite sure why our hearts were beating or even what purpose they served. Eventually, we realized Hydrochloric Acid Production of the Stomach: that these thumping organs serve the vital task of pumping clean blood throughout the body. But how? Edmond Hui investigates how it all works by taking a closer look at the heart’s highly efficient ventricle system. This tutorial will help you to understand how digestive tissue can produce a concentrated acid without damage to cells and molecules that are exposed to the acid. Hydrochloric acid production is described in this animation. This challenging tutorial addresses the concept at a high level of complexity. Hypersensitivity Type 2 and Blood Types: Illustrating the process of diffusion : Hypersensitivity refers to excessive, undesirable reactions produced by the normal immune system. Type 2 hypersensitivity is also known as cytotoxic hypersensitivity and may affect a variety of organs and tissues. This animation relates hypersensitivity and blood types together. This virtual manipulative will help the students to understand that osmosis is the movement of water molecules from an area of high concentration across a semipermeable membrane to an area of Interactive Animations: Cellular Transport: Interactive Cell Animations: Introduction to Infectious Diseases: Introduction to the Cell Membrane: low concentration. This illustration of the diffusion process will help the students to understand the concept of osmotic pressure which is created by the movement of the water based on their concentration gradient and thus resulting in the difference of the solute concentration. This animation offers an overview of membrane structure and demonstrates how the membrane acts as a highly selective barrier. Opportunities are provided to observe diffusion/osmosis, passive transport, and active transport in action. This is an online resource that uses interactive models for students to click on to learn about the cell. The visual representation will have students distinguish between animal and plant cells and also learn about the permeability of the cell membrane. A PowerPoint with speaker notes covering infectious diseases, causes, transmission, and control. This Khan Academy tutorial addresses the importance of the phospholipid bilayer in the structure of the cell Introduction to the Endocrine System: Kidney Function: Lobe-Oratorium: Mechanism of Steroid Hormone Action: Megacell - The Cell and its Organelles Game: membrane. The types of molecules that can diffuse through the cell membrane are also discussed. This Khan Academy video tutorial describes the basics of the endocrine system and the role of hormones as the communicators of the body. The major endocrine glands and the hormones that they produce are explained. This video presentation is illustrating the amount of work the kidney performs each day to maintain proper levels of ions in the body. It will help in increasing your understanding about the functions of kidney. This interactive game provides students with examples of the functions the different lobes of the brain are responsible for Students learn how the different parts of the brain work This tutorial will help you to understand how hormones influence the growth and development of organisms. The Cell and its Organelles educational game is based on the 1974 Nobel Prize in Physiology or Medicine, which was awarded for discoveries concerning the structure and organization of the vital components of a cell. Students playing the game will learn what an ultracentrifuge is used for; what the names of the compartments of the cell are; and what functions the various organelles have in the cell. This interactive cell membrane simulation allows students to see how different types of channels allow particles to move through the membrane. Sample learning goals: Membrane Channel Simulations: Metabolic Process Location: Predict when particles will move through the membrane and when they will not. Identify which particle type will diffuse depending on which type of channels are present. Predict the rate of diffusion based on the number and type of channels present. This tutorial will help the learners to understand the Microscope Mathematics: Mineral Transport in Plants: Molecular Expressions: Introduction to microscopy: Movement of Oxygen and Carbon Dioxide: functions and metabolic processes carried out by various organs involved in metabolism. Metabolic processes are not evenly shared between the different organs and tissues in the body. In fact, the cells of these different organs and tissues often specialize in aspects of catabolism, biosynthesis, and regulation. Learn how you can use a microscope as a tool to measure objects. This tutorial will help you to understand how minerals are absorbed by the root hair in plants. This site provides an introduction to microscopy and microscopes including history, images, and interactives. This tutorial will help you to understand how the movement of oxygen and carbon dioxide takes place between the alveoli and the blood by taking partial pressure into consideration. Oxygen diffuses from the air through the alveoli into the blood and carbon dioxide diffuses from the blood into the alveoli. This occurs due to differences in partial pressures. Movement Through a Plant: Moving Muscle Filaments: Muscle Contraction: Muscle Fibers and Motor Units: This challenging tutorial addresses the concept at a high level of complexity. The cohesion-tension theory describes how fluids move up the xylem to the leaves of a tree. With this tutorial learners will understand how water moves through a plant. Absorption and transpiration work together with cohesion and tension to move fluids from the soil, through the roots, and up through the tops of the tree. Strengthen your understanding of how muscle filaments function as this physiologist flexes his knowledge. This tutorial will help students understand the process of muscle contraction. A muscle contains many muscle fibers and each fiber contains a bundle of 4-20 myofibrils. Each fibril is striated and these striations are produced by the arrangement of thick and thin filaments, called actin and myosin. The contraction and relaxation of these actin and myosin filaments help muscles move. Get mentally fit as this physiologist explains muscle structure! Myosin and Actin: Nerve Impulse Transmission: Nerve Signaling Game: Neuron: This Khan Academy video describes how the proteins myosin and actin interact to produce a mechanical force on muscles, allowing them to move. The transmission of a nerve impulse along a neuron from one end to the other occurs as a result of electrical changes across the membrane of the neuron. This tutorial will help students to visualize and understand the transmission of a nerve impulse. This game is based on several Novel Prizes in Physiology or Medicine from 1906 until today that have been awarded for discoveries related to nerve signaling. Student playing the game will learn... -How are nerve cells composed? -How do nerve cells carry the signals that coordinate all the activities in our body? -How has the research into neuroscience developed through the 20th century? In this simulation, you will explore how neurons conduct electrical impulses by using the action potential. This phenomenon is generated through the flow of positively charged ions across the neuronal membrane. Stimulate a neuron and monitor what happens. You can pause, rewind, and move forward in time in order to observe the ions as they move across the neuron membrane. Other ways to explore: Nutrional Value of Food Using a Bomb Calorimeter: Describe why ions can or cannot move across neuron membranes. Identify leakage and gated channels, and describe the function of each. Describe how membrane permeability changes in terms of different types of channels in a neuron. Describe the sequence of events that generates an action potential. This tutorial will help you to understand how the nutritional value of food can be measured on many different scales. The most basic measurement scale is the free energy content in the food, i.e., how much energy is released when Organs of Digestion: Parts of the Cell: Phagocytosis: chemical bonds within the food are broken. This tutorial explores the steps that food takes on its journey through the digestive system. All major digestive organs and the process of nutrient absorption are explained. This Khan Academy tutorial describes the differences between prokaryotic and eukaryotic cells. It then goes on to discuss in detail the structures and their functions found in the eukaryotic cell. This tutorial will help you to understand the function of phagocytes. Phagocytes are specialized cells that ingest and break down foreign material including bacteria and viruses. This challenging tutorial addresses the concept at a high level of complexity. Learn how to identify explicit evidence and understand implicit meaning in a text. Plant Organs: This tutorial is designed to help you learn the concepts and skills from Grades 9-12 Biology to relate the structure of each of the major plant organs and tissues to physiological processes. Post Stroke Inflammation: Prokaryotes, Eukaryotes, & Viruses Tutorial: Proton Pump: Reflex Arc: You will enhance your familiarity with the structure, function, and evolutionary origins of plant tissues and organs. Learn about post-stroke inflammation. This a mostly text resource that provides accurate, straight-forward descriptions of prokaryotes, eukaryotes, and viruses. It could be a great tool to help students compare and contrast organisms with each other and viruses, or a good review passage. This tutorial will help you to understand how a concentration gradient across a membrane is used. When a molecule or an ion is moved across a membrane from an area of low concentration to an area of high concentration then a gradient is generated. This gradient can be chemical or it can also create a difference in electrical charge across the membrane if ions are involved. The proton pump generates an electrical and chemical gradient that can be used to create ATP which can drive a large number of different biochemical reactions. This tutorial will help students to understand the Regulated Secretion: Risk Factors for Coronary Artery Disease: Risk Factors for Stroke: Role of Phagocytosis in Nonspecific Immunity: process of reflex arc. A reflex arc is the nerve pathway which makes a fast, automatic response possible.When the safety of an organism demands a very quick response, the signals may be passed directly from a sensory neuron, via a relay neuron, to a motor neuron for instant, unthinking action. This is a reflex action. This online tutorial will help you to understand the process of regulated secretion. In regulated secretion, proteins are secreted from a cell in large amounts when a specific signal is detected by the cell. The specific example used in this tutorial is the release of insulin after a glucose signal enters a pancreatic beta cell. Learn about the risk factors for coronary artery disease including modifiable and nonmodifiable risk factors. In this Khan Academy video you will learn some of the modifiable and non-modifiable risk factors that can lead to a stroke. This Khan Academy video describes non specific immunity, and the specific role of phagocytes. The tutorial explains how phagocytes Secondary Active Transport in the Nephron: Sensory Systems in Plants: Signal Molecules of the Endocrine System: engulf pathogens that enter the body as a line of defense. This Khan Academy video discusses which ions are allowed to be actively transported out of the filtrate of urine. The process of secondary active transport in the nephron is described in detail. This tutorial will help you to understand phytochromes in plants and how they affect plant growth. Phytochromes are pigment containing proteins that play an important role in plant regulation, including the germination of seeds. This tutorial demonstrates how the structure of a signal molecule determines its function. Signal molecules can interact with either intracellular or extracellular receptors. For a signal molecule to bind with an intracellular receptor it must be able to pass through the cellular membrane. Generally signal molecules that enter the cell are nonpolar and fat soluble. These signal molecules can pass through the lipid bilayer of the cell membrane. Signals that bind with extracellular receptors are proteins or other types of molecules that cannot readily pass through the membrane. Signal Transduction: Signal Transduction: Skeletal Muscle Physiology: Sodium Potassium Exchange Pump: This challenging tutorial addresses the concept at a high level of complexity. The human body consists of a wide variety of cell types that must work together to sustain the life of an organism. They must respond to their environment and communicate with each other in a process called signal transduction. This tutorial will help the learners understand the process of signal transduction. This interactive virtual manipulative will help the students in understanding how the wide variety of cell types work together to sustain the life of an organism. In this animation students will observe the complex biochemical process of how cells respond to their environment and communicate with each other in a process called signal transduction. Get moving and learn how muscles move you! This tutorial will help you to understand how sodium and potassium ions are pumped in opposite directions across a membrane building up a Sound: T-Cell Dependent Antigens: Test Your Science IQ: Cells: The Blood Typing Game: The Cardiac Cycle: chemical and electrical gradient for each. These gradients can be used to drive other transport processes. This tutorial provides information about the sound and how it travels. It also includes information on the anatomy and physiology of the human ear for the learners to understand how sound passes through the ear. T-cells perform a wide variety of functions in the immune system. In this tutorial you will understand the structure and function of the Tcells. A collection of questions that tests students' knowledge about cells This educational game is about blood types, blood typing, and blood transfusions. Your challenge is to save patients in urgent need of blood transfusions. Your job is to decide what blood type these patients belong to in order to administer safe blood transfusions. At the end you will be evaluated: if you make no mistakes at all you will get all five blood drops. The cardiac cycle is defined as the complete heartbeat from generation to the beginning of the The Circulatory System and the Heart: The Immune Response: The Immune System Game: The Immune System: Your Body’s Private Defense System: next beat, and includes the diastole, the systole, and the intervening pause. This tutorial will help you to understand the cardiac cycle. This Khan Academy video explains the major vessels involved in the flow of blood and follows the steps that blood takes as it travels through the heart. This tutorial will help students understand how the immune system of vertebrates is characterized by acquired responses that are highly specific to particular antigens. This system has the advantage of having a cellular memory for previous infections. In this game, you are a trainee soldier of the Immune System Defense Forces, defending a human against bacterial infection. You have two missions to complete. In this first, you must command a team of white blood cells called granulocytes to fight against bacteria invading the blood system through a finger wound. In the second mission, you must commond an army of macrophages and dendritic cells to fight the invading bacteria. By the end of this tutorial you should be able to identify the basic functions of the immune system. You will also be able to distinguish between nonspecific and specific immune responses. The Lungs and Pulmonary System: The Nerve Impulse: The Role of Vitamins in Human Nutrition: This Khan Academy video discusses form and function in the respiratory system. All of the respiratory organs are discussed. This tutorial explains that the source of the impulse in a neuron is a rapid change in the polarity of the cell membrane in a restricted area. The direction of the electrical gradient is rapidly reversed and then returns to normal. The change in charge stimulates the process to happen in adjacent parts of the cell and the change in the polarity travels down the neuron. This tutorial will help you to understand the role that vitamins play in human nutrition. Vitamins interact with enzymes to allow them to function more effectively. Though vitamins are not consumed in metabolism, they are vital for the process of metabolism to occur. The Tuberculosis Experiments and Discoveries Game: Three Phases of Gastric Secretion: Treatment of Stroke with Interventions: Tropomyosin and Troponin and Their Role in Muscle Contraction: This challenging tutorial addresses the concept at a high level of complexity. This game explores the 1905 Nobel prize in Physiology or Medicine, which was awarded for investigations and discoveries concerning the disease tuberculosis or "TB." The game is a sort of old fashioned laboratory simulation and allows students to discover and experience some of the classic methods used to detect whether a specific bacterium causes a disease. This tutorial will help students understand how food is digested with the help of different gastric secretions. Gastric juice from glands renders food particles soluble, initiates digestion, and converts the gastric contents to a semiliquid mass called chyme, thus preparing it for futher disgestion in the small intestine. In this Khan academy video tutorial, learn about the possible treatments and interventions of different types of strokes. This Khan Academy video explains the role that tropomyosin and tropinin play in muscle contraction. The role of the calcium ion concentrations are also explained. Types of Immune Responses: Types of Microscopes: Vaccine and Active Immunity: Virus: This challenging tutorial addresses the concept at a high level of complexity. This Khan Academy video contains an overview of the types of immune responses in the body. The differences between humoral adaptive immunity and cell mediated immunity are discussed in detail. By the end of this tutorial, you should be able to determine differences and similarities of the structure and function of compound light microscopes, dissecting microscopes, scanning electron microscopes and transmitting electron microscopes. A vaccine allows a person to develop acquired immunity against an illness without actually getting the disease. This interactive tutorial will help the learners to understand the process by which vaccines work in the human body. This tutorial will help the student understand about viruses which are small infectious agents that Voltage-Gated Channels and the Action Potential: Water Transport in Plants: What Causes Antibiotic Resistance?: What is a Stroke?: What Makes Your Blood Flow?: replicate only inside the living cells of other organisms. This tutorial explains how a charge is generated across a membrane. The function and role of the voltagegated sodium ion channel and voltage-gated potassium ion channel are explained in detail. This tutorial will help you to understand how plant cells intake water. This animation shows how water is transported from the root systems of plants upwards to the leaves. This short video describes the process of antibiotic resistance. Right now, you are inhabited by trillions of micro organisms. Many of these bacteria are harmless (or even helpful!), but there are a few strains of ‘super bacteria’ that are pretty nasty -- and they’re growing resistant to our antibiotics. Why is this happening? Kevin Wu details the evolution of this problem that presents a big challenge for the future of medicine. Learn the conditions present in your brain that cause a stroke. Learn about factors that affect the blood flow in your body in this interactive tutorial. This video presentation will help to understand the regeneration process in a zebrafish. When the zebrafish heart is damaged, the wound site is rapidly sealed with a fibrin clot that stems bleeding within seconds. Following clot formation, the tissue that surrounds the heart muscle, the epicardium, gradually covers the fibrin clot via migration and cell division. Over the next few months, new cardiac muscle is produced and replaces the clot. Zebrafish Heart Regeneration: Parent Resources Title Blood Typing: Cell Anatomy: Cellular Transport: Description This virtual manipulative will provide the students with the opportunity to choose a correct blood type for the patients and administer blood transfusion. The students will have the chance to check the blood type before starting the transfusion. The knowledge and understanding of blood groups will also be tested during the activity. This tutorial will help the learners to learn about the anatomy of the cell. As the learners move the cursor over each cell organelle, they are shown information about that organelle's structure and function. This activity will help the students to learn about the cellular transport which is referred as the movement of compounds across the outer wall or membrane of the cell. Students will recognize that the purpose of cell transport is to maintain homeostasis. While navigating this activity, students will gain a better understanding of the different types of transport that occurs across a membrane barrier, such as diffusion, osmosis, active and passive transports. The diabetic dog educational game is based on the discovery of the hormone insulin, which made it possible to treat the patients with diabetics. This activity will help the students to recognize some important facts about diabetes such as: Diabetic Dog Game: Electrocardiogram: what is the diabetes? what happens to the blood sugar level when some one has diabetes? what is insulin? what shall someone suffering form diabetes do if they have high blood sugar level? what shall someone suffering form diabetes do if they have low blood sugar levels? This educational game is based on the discovery of the electrocardiogram,(ECG). ECG is used for recording the small electric waves being generated during heart activity, a simple way of diagnosing heart conditions. This game lets the students explore the key elements of the electrocardiogram for measuring the heart beats and analyze the mountains and valleys in the ECG curve. Some of the sample learning goals can be: Illustrating the process of diffusion : Interactive Cell Animations: Mapping the Brain: Megacell - The Cell and its Organelles Game: For what do we use ECG? What does the mountains and valleys of the ECG curves stand for? What can you find out about the heart with an ECG? This virtual manipulative will help the students to understand that osmosis is the movement of water molecules from an area of high concentration across a semipermeable membrane to an area of low concentration. This illustration of the diffusion process will help the students to understand the concept of osmotic pressure which is created by the movement of the water based on their concentration gradient and thus resulting in the difference of the solute concentration. This is an online resource that uses interactive models for students to click on to learn about the cell. The visual representation will have students distinguish between animal and plant cells and also learn about the permeability of the cell membrane. This PBS virtual interaction allows students to map the brain using six different realistic virtual imaging techniques. Students are able to view color-coded regions of the brain and explanations of the functions of major brain parts are available as well. The Cell and its Organelles educational game is based on the 1974 Nobel Prize in Physiology or Medicine, which was awarded for discoveries concerning the structure and organization of the vital components of a cell. Students playing the game will learn what an ultracentrifuge is used for; what the names of the compartments of the cell Movement Through a Plant: Moving Muscle Filaments: Muscle Fibers and Motor Units: Nerve Signaling Game: Neuron: are; and what functions the various organelles have in the cell. The cohesion-tension theory describes how fluids move up the xylem to the leaves of a tree. With this tutorial learners will understand how water moves through a plant. Absorption and transpiration work together with cohesion and tension to move fluids from the soil, through the roots, and up through the tops of the tree. Strengthen your understanding of how muscle filaments function as this physiologist flexes his knowledge. Get mentally fit as this physiologist explains muscle structure! This game is based on several Novel Prizes in Physiology or Medicine from 1906 until today that have been awarded for discoveries related to nerve signaling. Student playing the game will learn... -How are nerve cells composed? -How do nerve cells carry the signals that coordinate all the activities in our body? -How has the research into neuroscience developed through the 20th century? In this simulation, you will explore how neurons conduct electrical impulses by using the action potential. This phenomenon is generated through the flow of positively charged ions across the neuronal membrane. Stimulate a neuron and monitor what happens. You can pause, rewind, and move forward in time in order to observe the ions as they move across the neuron membrane. Other ways to explore: Describe why ions can or cannot move across neuron membranes. Identify leakage and gated channels, and describe the function of each. Signal Transduction: Skeletal Muscle Physiology: Sound: The Blood Typing Game: The Immune System Game: Describe how membrane permeability changes in terms of different types of channels in a neuron. Describe the sequence of events that generates an action potential. This interactive virtual manipulative will help the students in understanding how the wide variety of cell types work together to sustain the life of an organism. In this animation students will observe the complex biochemical process of how cells respond to their environment and communicate with each other in a process called signal transduction. Get moving and learn how muscles move you! This tutorial provides information about the sound and how it travels. It also includes information on the anatomy and physiology of the human ear for the learners to understand how sound passes through the ear. This educational game is about blood types, blood typing, and blood transfusions. Your challenge is to save patients in urgent need of blood transfusions. Your job is to decide what blood type these patients belong to in order to administer safe blood transfusions. At the end you will be evaluated: if you make no mistakes at all you will get all five blood drops. In this game, you are a trainee soldier of the Immune System Defense Forces, defending a human against bacterial infection. You have two missions to complete. In this first, you must command a team of white blood cells called granulocytes to fight against bacteria invading the blood system through a finger wound. In the second mission, you must commond an army of macrophages and dendritic cells to fight the invading bacteria. This game explores the 1905 Nobel prize in Physiology or Medicine, which was awarded for investigations and discoveries concerning the disease tuberculosis or "TB." The game is a sort The Tuberculosis Experiments and Discoveries Game: of old fashioned laboratory simulation and allows students to discover and experience some of the classic methods used to detect whether a specific bacterium causes a disease.