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BIO 12 - Name: ________________________ Date: March 30, 2017 DUE: April 3/17 Section 10-3 Regulating the Cell Cycle (pages 250-252) – Value 24 Controls on Cell Division (page 250) 1. What happens to the cells at the edges of an injury when a cut in the skin or a break in a bone occurs? (2 pts) ____________________________________________________________________________ ________________________________________________________________________________________ 2. What happens to the rapidly dividing cells when the healing process nears completion? (2 pts) _____________________________________________________________________________________ _____________________________________________________________________________________ Cell Cycle Regulators (page 251) 3. What do cyclins regulate? (2 pts) _____________________________________________________________________________________ _____________________________________________________________________________________ 4. What are internal regulators? (2 pts) _______________________________________________________________________________________ _______________________________________________________________________________________ 5. Circle the letter(s) of each sentence that is true about external regulators. (3 pts) a. They direct cells to speed up or slow down the cell cycle. b. They prevent the cell from entering anaphase until all its chromosomes are attached to the mitotic spindle. c. They include growth factors. d. They prevent excessive cell growth and keep the tissues of the body from disrupting one another. Uncontrolled Cell Growth (page 252) 6. What is cancer? (2 pts) 7. Complete the flowchart about cancer. (3 pts) Cancer cells don’t respond to signals that regulate Cancer cells form masses of cells called Cancer cells break loose and spread throughout the Reviewing Key Skills – Section 10-3 8. Applying Concepts Do all cells in the body have the same growth rate? Why or why not? (2 pts) ________________________________________________________________________________ ________________________________________________________________________________ 9. Posing Questions - Cyclins seems to regulate the cell cycle. What questions might scientists have asked following the discovery of cyclins? (2 pts) _______________________________________________________________________________ _______________________________________________________________________________ 10. Comparing and Contrasting - What are the similarities and the differences between internal and external cell cycle regulators? (2 pts) Similarities: _________________________________________________________________________________________ _____________________________________________________________________________________ _____________________________________________________________________________________ Differences: _____________________________________________________________________________________ _____________________________________________________________________________________ _____________________________________________________________________________________ 11. Inferring - Describe a situation in the human body that would cause an increase in the rate of cell division of certain cells, followed by a return to the normal rate of division. (2 pts) _____________________________________________________________________________________ _____________________________________________________________________________________ _____________________________________________________________________________________ _____________________________________________________________________________________ _____________________________________________________________________________________ _____________________________________________________________________________________ TOTAL VALUE 24