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ABO Blood Types The most well-known and medically important blood types are in the ABO group. They were discovered in 1900 and 1901 at the University of Vienna by Karl Landsteiner in the process of trying to learn why blood transfusions sometimes cause death and at other times save a patient. In 1930, he belatedly received the Nobel Prize for his discovery of blood types. All humans and many other primates can be typed for the ABO blood group. There are four principal types: A, B, AB, and O. There are two antigens and two antibodies that are mostly responsible for the ABO types. Blood Types Multiple Alleles – more than the usual two alleles for a trait Codominance – Both alleles will be present A = dominant to O B = dominant to O O = recessive AB = codominant Genotypes A = AA, AO B = BB, BO AB = AB O = OO The specific combination of these four components determines an individual's type in most cases. The table below shows the antigens and antibodies with the corresponding ABO type "THE RAREST BLOOD TYPE IS THE TYPE THAT'S NOT AVAILABLE WHEN YOU NEED IT!" Blood Type & Rh How Many Have It Frequency O Rh Positive 1 person in 3 37.4% O Rh Negative 1 person in 15 6.6% A Rh Positive 1 person in 3 35.7% A Rh Negative 1 person in 16 6.3% B Rh Positive 1 person in 12 8.5% B Rh Negative 1 person in 67 1.5% AB Rh Positive 1 person in 29 3.4% AB Rh Negative 1 person in 167 .6% Universal Donor = O Universal Acceptor = AB Mrs. Smith and Mrs. Jones shared a room in the maternity ward. Mrs. Smith is certain the baby she brought home is not hers. Can you help her???? Mrs. Smith = AB Mr. Smith = O Baby at Smiths = O Mrs. Jones = A Mr. Jones = A Baby at Jones = A