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Transcript
7th Grade Science Assessment
Name______________________
RIO Unit 15- Human Genetic Disorders
1. Anemia is a blood disorder affecting the
quantity of red blood cells and/or hemoglobin.
Anemia can be inherited or influenced by
environmental factors or lifestyle choices. Which
of the following cases is an example of an
inherited form of anemia?
A. A person chooses to not eat red meat,
spinach, or other foods high in iron.
B. A lack of oxygen causes red blood cells
to change into a sickle shape.
C. A car accident causes the loss of a large
quantity of blood.
D. A person’s friend has anemia
2. Hemophilia is caused by a (n)
A. Recessive allele on the X chromosome
B. Extra chromosome
C. Dominant allele
D. Co dominant allele
3. What makes Down Syndrome occur most
often?
A. A person inherits a recessive allele
B. Chromosomes fail to separate properly
C. Sickle-shaped cells become stuck in the
blood vessels
D. Blood fails to clot properly
4.What genetic disorder results in abnormally
shaped blood cells?
A. Hemophilia
B. Down Syndrome
C. Cystic fibrosis
D. Sickle-cell disease
5. What are genetic disorders caused by?
A. Changes in chromosomes
B. Dominant alleles only
C. Recessive alleles only
D. Pedigrees
6. Which genetic disorder causes the body to
produce unusually thick mucus in the lungs and
intestines?
A. Hemophilia
B. Down syndrome
C. Cystic fibrosis
D. Sickle-cell disease
7. What would be the best way to predict the
probability of a baby having cystic fibrosis?
A. By studying the parent’s karyotypes
B. By studying the family’s pedigree chart
C. By exploring genetic engineering
D. Determining if parents have co
dominant alleles
8. What is a mutation?
A. Any change that is harmful to an
organism
B. Any change in a gene or chromosome
C. Any change that is helpful to an
organism
D. Any change in the phenotype of a cell
9. What makes a mutation harmful to an
organism?
A. Changes the DNA of the organism
B. Changes the phenotype of the organism
C. Reduces the organism’s chances for
survival and reproduction
D. Makes the organism better able to avoid
predators
Use the below pedigree to help answer questions 10-13. The pedigree below shows the inheritance of
sickle-cell anemia, a genetic disease, in a particular family. The shaded symbols represent individuals with
sickle-cell anemia. The unshaded symbols represent individuals who do not have sickle cell anemia but
may be carriers.
1
1
2
3
4
2
5
3
6
7
10. The father in generation 2 has sickle-cell
anemia. How many of his children have sicklecell anemia?
A.
B.
C.
D.
1
2
3
4
11. According to the pedigree, how many
daughters do the parents in generation I have?
A.
B.
C.
D.
0
1
2
3
12. Which family members are carriers of sickle
cell disease?
A. 1, 2, 3, 6, 7, 8
B. 2, 3, 4, 5, 6, 7
C. 4, 5, 6, 7, 8, 9
D. none of them are carriers
13. Sickle-cell anemia is a genetic disorder of
the blood in which the shape of red blood cells is
distorted, resulting in a variety of health
problems. The allele for normal blood cell
production (H) is dominant to the allele for
sickle cell production (h). Which of the
following is true about the parents in generation
1?
8
9
A. The father is homozygous dominant
(HH) and the mother is homozygous
recessive (hh).
B. Each parent is heterozygous (Hh) for
sickle-cell anemia.
C. Each parent is homozygous dominant
(HH) for sickle-cell anemia.
D. Each parent is homozygous recessive
(hh) for sickle-cell anemia.
14. What has genetic counseling allowed people
to do?
A. Purchase disease resistant crops
B. Create babies with the color hair that
the parents want
C. Let parents know about genetic diseases
that their children might have
D. Genetic counseling is science fiction
and does not now exist.