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VCE Biology Unit 1: Digestion Getting the 'Goodness' to our Cells An overview of the Digestive system of humans 1. INGESTION: Food must be taken into our body. Humans and many other organisms take food into their body through their mouth. We call this eating. 2. MASTICATION: Food is chewed to break large pieces into small ones*. Food is mixed with saliva 3. DIGESTION: large organic molecules must be chemically broken down into its simplest components; amino acid (units that make up proteins), monosaccharides eg. glucose (units that make up carbohydrates), glycerol and fatty acids(units that make up lipids), nucleotides (units that make up nucleic acids), so that they can be absorbed. Some substances do not need to be chemically broken down into smaller components e.g. water, vitamins, and minerals The efficient digestion of food relies on two main forms of breakdown: Mechanical breakdown: physical breaking up of large pieces into smaller pieces. (In humans assisted mostly by teeth (chewing action) and to a lesser extent by churning of food in stomach) Chemical breakdown: breaking of chemical bonds so that larger molecules are broken into smaller building blocks(molecules) 3. ABSORPTION: nutrients and water must pass across the wall of the stomach (minor role) and intestine (major role), into the surrounding tissue fluid, and then into the circulatory system (amino acids, monosaccharides, micronutrients water) or lymphatic system (products of lipid digestion). Nutrients are then transported, primarily via the circulatory system of the organism, to body cells where they are utilized. 4. EGESTION: material that is not absorbed as it passes through the alimentary canal are stored temporarily in the rectum before being eliminated via the anus. Introducing the Digestive SYSTEM: A summary Complete the table below: Use sheets, text book, SRAM and video to assist Under each component are some key words in italics that you must include in your comments about structure and function. You can use dot points and short hand to complete the table. Name of Digestive system component Mouth Role: What is the function of this component mechanical breakdown of food How is it suited it to its function. chemical digestion of cooked starch in food Salivary glands: secrete saliva containing liquids and a type of amylase called ptyalin. Saliva also lubricates food to enable it to easily move through this alimentary canal. break moisten lubricate nose trachea stop saliva enzyme starch 1 Teeth: cut tear and grind food to break it into smaller pieces. This makes swallowing easier but also importantly increase the surface area exposed to enzymes. This enables a faster rate of chemical digestion than if the food was not chewed by the teeth. VCE Biology Unit 1: Digestion mixing of foods with saliva Tongue: moves food around the mouth, forming it into a bolus and pushing it to the back of the mouth for swallowing soft palate: stops food from moving from the mouth up into the nose during swallowing epiglottis: flap that covered the tachea during swallowing- stops food moving into the trachea during swallowing thus ensuring that it moves down the oesophagus and into the stomach oesophagus peristalsis bolus cardiac Sphincter ring stomach Muscular layers pepsin hydrochloric acid, chyme glandular layer mucus pH Transports food from the mouth to the stomach. Thin tube with a muscular lining Wave like contractions of the muscular wall of the oesophagus, known as peristalsis, move the bolus of food from the mouth to the stomach Stops or reduces reflux of gastric juices into the oesophagus. short term storage while digestion is taking place muscular ring that stops gastric juices rising some mechanical breakdown Stomach wall consist of several muscular layers. This muscle churns stomach contents and mixes the food with gastric juices to form a soupy mixture called chyme mixing of food with gastric juices Chemical breakdown to proteins to peptides absorption of some substances: those simple enough to be absorbed without needed digestion (e.g. water, alcohol, glucose, aspirin) it has folds(rugae) that allow for expansion of stomach as it fills Glandular layer: goblet cells in lining of the stomach produce and secrete mucus. This mucus provides a protective coating that reduces the chance of HCl and proteases damaging or digesting the stomach lining glandular cells that secrete HCl. This creates a very acidic environment (pH 1-2) in the stomach which is required for the function of pepsin. pyloric sphincter ring controls controls the release of chyme from the stomach into the duodenum 2 glandular cells that secrete the enzyme pepsin in its inactive form pepsinogen. If the acidic medium of the stomach pepsinogen is converted to pepsin. Pepsin is the enzyme that catalyses the chemical breakdown of protein. ring of muscle at the base of the stomach VCE Biology Unit 1: Digestion chemical breakdown of proteins, lipids and carbohydrates duodenum Secretions enzymes chemical breakdown glandular layer that is responsible for secretion of enzymes that chemically digest proteins(proteases), lipids(lipases) and carbohydrates(amylases) secretions from liver and gall bladder Liver & Gall bladder emulsify lipids surface area Pancreas Bicarbonate ions pancreatic enzymes pH liver produces and secretes bile which emulsifies lipids, giving them a larger surface area on which lipases can act. This enable an increased rate of chemical digestion of lipids. Produce and secrete digestive enzymes and bicarbonate. The enzymes enable chemical digestion of some molecules. The bicarbonate neutralizes the chyme and creates a slightly basic pH(6~8) which is the optimum pH for the enzymes of the small intestine and pancreas to function in. Large intestine colon Absorption water Bacteria rectum Anus Pancreatic duct: carries enzymes and bicarbonate to the duodenum. some chemical digestion villi line the intestinal wall. In the centre of each villus is a lacteal and a capillary. much absorption of nutrients(amino acids, monosaccarides, fatty acids etc), vitamins, minerals and water (most water is absorbed here) Villi and microvilli create a very large surface area over which absorption of nutrients can take place. This enables fast rate of absorption Ileum Villi absorption capillary lacteal fats amino acids monosaccharides Bile duct: bile enters the duodenum from the gall bladder, via the bile duct further absorption of water Amino acids and monosaccharides pass across the villus and into the capillary. fats pass across the villus and into the lacteal glandular lining that secretes mucus bacteria within colon synthesise some vitamins storage of faecal matter prior to egestion control the release of faeces from the rectum muscle ring 3 The anus is a ring of muscle at the base of the rectum. It expands and contracts to control the release of faeces VCE Biology Unit 1: Digestion Secretions of the digestive system Name of secretion (~ ph of secretion) Saliva (slightly alkaline) Gastric juice (pH 1-1.5) Site of production Site of action Chemical components of secretion (*= an enzyme) Action salivary glands stomach lining mouth salivary amylase* a.k.a. ptyalin Hydrochloric acid Begins digestion of cooked starch creates the acidic pH (1.52) that pepsin need to function optimally stomach (lumen) pepsin* Bile (pH 7.5) Pancreatic juice (pH 7.1-8.2) Intestinal juice (pH 7.6) liver pancreas intestines chemical digestion of proteins rennin* coagulates milk bile salts emulsify lipids duodenum duodenum intestines Bicarbonate ions neutralize chyme and make ph slightly basic (~8) Amylase* chemical digestion of starch to maltose trypsin* chemical digestion of protein polypeptides peptidase* chemical digestion of peptides into amino acids lipase* chemical digestion of lipids to fatty acids and glycerol digestion of carbohydrates various amylases* peptidase* chemical digestion of peptides into amino acids 4